IT8322648A0 - Derivati dell'acido 4-fenil4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali. - Google Patents

Derivati dell'acido 4-fenil4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali.

Info

Publication number
IT8322648A0
IT8322648A0 IT8322648A IT2264883A IT8322648A0 IT 8322648 A0 IT8322648 A0 IT 8322648A0 IT 8322648 A IT8322648 A IT 8322648A IT 2264883 A IT2264883 A IT 2264883A IT 8322648 A0 IT8322648 A0 IT 8322648A0
Authority
IT
Italy
Prior art keywords
phenyl4
buten
oxo
derivatives
application
Prior art date
Application number
IT8322648A
Other languages
English (en)
Other versions
IT1169783B (it
Inventor
Fernando Barzaghi
Mario Bianchi
Original Assignee
Roussel Maestretti Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Maestretti Spa filed Critical Roussel Maestretti Spa
Publication of IT8322648A0 publication Critical patent/IT8322648A0/it
Priority to IT22648/83A priority Critical patent/IT1169783B/it
Priority to PT78942A priority patent/PT78942B/pt
Priority to ZA846107A priority patent/ZA846107B/xx
Priority to IL72682A priority patent/IL72682A/xx
Priority to US06/642,249 priority patent/US4594443A/en
Priority to SU843783011A priority patent/SU1333233A3/ru
Priority to HU843173A priority patent/HU191714B/hu
Priority to GR80172A priority patent/GR80172B/el
Priority to MA20434A priority patent/MA20210A1/fr
Priority to NZ209330A priority patent/NZ209330A/en
Priority to ES535411A priority patent/ES8505922A1/es
Priority to AT84401718T priority patent/ATE37533T1/de
Priority to AU32353/84A priority patent/AU565492B2/en
Priority to EP84401718A priority patent/EP0134179B1/fr
Priority to DE8484401718T priority patent/DE3474298D1/de
Priority to CA000461789A priority patent/CA1216859A/fr
Priority to JP59175301A priority patent/JPS6072843A/ja
Priority to FI843354A priority patent/FI79524C/fi
Priority to KR1019840005167A priority patent/KR850001724A/ko
Priority to MX801684A priority patent/MX158001A/es
Application granted granted Critical
Publication of IT1169783B publication Critical patent/IT1169783B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/08—Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
IT22648/83A 1983-08-25 1983-08-25 Derivati dell' acido 4-fenil 4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali IT1169783B (it)

Priority Applications (20)

Application Number Priority Date Filing Date Title
IT22648/83A IT1169783B (it) 1983-08-25 1983-08-25 Derivati dell' acido 4-fenil 4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali
PT78942A PT78942B (fr) 1983-08-25 1984-07-19 Procede de preparation de nouveaux derives de l'acide 4-phenyl 4-oxo buten-2-oique
ZA846107A ZA846107B (en) 1983-08-25 1984-08-07 Derivatives of 4-phenyl-4-oxo-buten-2-oic acid,the process for preparing them,their application as medicaments and the compositions containing them
IL72682A IL72682A (en) 1983-08-25 1984-08-14 Derivatives of 4-alkanoyloxy-phenyl-4-oxo-buten-2-oic acid,the process for preparing them and pharmaceutical compositions containing them
US06/642,249 US4594443A (en) 1983-08-25 1984-08-20 Derivatives of 4-phenyl-4-oxo-buten-2-oic acid and therapeutic use thereof
SU843783011A SU1333233A3 (ru) 1983-08-25 1984-08-21 Способ получени (Е)-4-(4-ацилоксифенил)-4-оксо-2-бутеновой кислоты
HU843173A HU191714B (en) 1983-08-25 1984-08-23 Process for the production of new 4-phenyl-4-oxo-2-butene carboxylic acid-derivatives
GR80172A GR80172B (en) 1983-08-25 1984-08-23 Process for the preparation of novel 4-phenyl 4-oxo buten-2-oic acid derivatives
MA20434A MA20210A1 (fr) 1983-08-25 1984-08-23 Procede de preparation de nouveaux derives de l'acide 4 - phenyl 4-oxo buten-2-oique.
ES535411A ES8505922A1 (es) 1983-08-25 1984-08-24 Procedimiento para preparar nuevos derivados del acido 4-fenil-4-oxo-buten-2-oico
NZ209330A NZ209330A (en) 1983-08-25 1984-08-24 Oxybenzene derivatives and pharmaceutical compositions
AT84401718T ATE37533T1 (de) 1983-08-25 1984-08-24 Derivate der 4-phenyl-4-oxo-buten-2-saeure, verfahren zu ihrer herstellung, medikamente und mischungen mit diesen derivaten.
AU32353/84A AU565492B2 (en) 1983-08-25 1984-08-24 4-phenyl-4-oxo-buten-2-oic acids
EP84401718A EP0134179B1 (fr) 1983-08-25 1984-08-24 Nouveaux dérivés de l'acide 4-phényl 4-oxo-buten 2-oique, leur procédé de préparation, des médicaments et des compositions les renfermant
DE8484401718T DE3474298D1 (en) 1983-08-25 1984-08-24 Derivatives of 4-phenyl-4-oxo-buten-2-oic acid, their preparation, medicaments and compositions containing them
CA000461789A CA1216859A (fr) 1983-08-25 1984-08-24 Procede de preparation de nouveaux derives de l'acide 4-phenyl 4-oxo buten-2-oique
JP59175301A JPS6072843A (ja) 1983-08-25 1984-08-24 ４−フエニル−４−オキソ−２−ブテン酸の新誘導体、それらの製造法、薬剤としての使用及びそれらを含む組成物
FI843354A FI79524C (fi) 1983-08-25 1984-08-24 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 4-fenyl-4-oxo-2-ensmoersyraderivat.
KR1019840005167A KR850001724A (ko) 1983-08-25 1984-08-25 4-페닐-4-옥소-부텐-2-오인산유도체의 제조방법
MX801684A MX158001A (es) 1983-08-25 1984-08-27 Procedimiento para preparar derivados del acido 4-fenil-4oxo-buten-2-oico

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22648/83A IT1169783B (it) 1983-08-25 1983-08-25 Derivati dell' acido 4-fenil 4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali

Publications (2)

Publication Number Publication Date
IT8322648A0 true IT8322648A0 (it) 1983-08-25
IT1169783B IT1169783B (it) 1987-06-03

Family

ID=11198831

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22648/83A IT1169783B (it) 1983-08-25 1983-08-25 Derivati dell' acido 4-fenil 4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali

Country Status (19)

Country Link
US (1) US4594443A (it)
EP (1) EP0134179B1 (it)
JP (1) JPS6072843A (it)
KR (1) KR850001724A (it)
AT (1) ATE37533T1 (it)
AU (1) AU565492B2 (it)
CA (1) CA1216859A (it)
DE (1) DE3474298D1 (it)
ES (1) ES8505922A1 (it)
FI (1) FI79524C (it)
GR (1) GR80172B (it)
HU (1) HU191714B (it)
IL (1) IL72682A (it)
IT (1) IT1169783B (it)
MA (1) MA20210A1 (it)
NZ (1) NZ209330A (it)
PT (1) PT78942B (it)
SU (1) SU1333233A3 (it)
ZA (1) ZA846107B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190340B (it) * 1986-06-06 1988-02-16 Roussel Maestretti Spa Derivati dell'acido 4-fenil 4-osso 2-butenoico,loro procedimento di preparazione e loro impiego come prodotti medicinali
DK49688A (da) * 1987-03-20 1988-09-21 Hoffmann La Roche Propiolophenonderivater
HU198292B (en) * 1987-09-25 1989-09-28 Richter Gedeon Vegyeszet Process for producing salicilates and pharmaceutical compositions comprising such active ingredient
HU211731B (en) * 1992-12-29 1996-02-28 Richter Gedeon Vegyeszet Process to prepare novel salicylic acid derivs. and pharmaceutical compns. contg. them
KR960703901A (ko) * 1993-08-19 1996-08-31 로즈 암스트롱 치환된 2(5H)푸라논, 2(5H)티오페논 및 2(5H)피롤론 유도체, 그의 제조 방법 및 엔도텔린 길항제로서의 그의 용도(Substituted 2(5H)Furanone, 2(5H)Thiophenone and 2(5H)Pyrrolone Derivatives, Their Preparation and Their Use as Endothelin antagonists)
US5922759A (en) * 1996-06-21 1999-07-13 Warner-Lambert Company Butenolide endothelin antagonists
WO1997008169A1 (en) * 1995-08-24 1997-03-06 Warner-Lambert Company Furanone endothelin antagonists
US5891892A (en) * 1996-10-29 1999-04-06 Warner-Lambert Company Small molecule biaryl compounds as inhibitors of endothelin converting enzyme
US20110067969A1 (en) * 2009-09-22 2011-03-24 Gm Global Technology Operations, Inc. Non-rotating clutch
PL3393530T3 (pl) * 2015-12-23 2022-12-05 Henkel Ag & Co. Kgaa Płyn do obróbki metali

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB588108A (en) * 1944-10-23 1947-05-14 Roche Products Ltd Manufacture of bacteriostatic substances
US2532579A (en) * 1946-08-06 1950-12-05 Du Pont Pest control compositions containing beta-acyl acrylates
US2562208A (en) * 1947-04-14 1951-07-31 Schering Corp Fungistatic composition
DE1282644B (de) * 1962-09-08 1968-11-14 Hoechst Ag Verfahren zur Herstellung von ungesaettigten ª€-Ketocarbonsaeureestern
DE2047806A1 (en) * 1970-09-29 1972-04-06 Dr Karl Thomae GmbH, 7950 Biberach 3-aroyl-acrylic acids - pharmaceutical intermediates prepd from acetophenones and glyoxylic acid derivs
DE2103749A1 (en) * 1971-01-27 1972-08-10 Dr. Karl Thomae GmbH, 7951 Biberach 3-acyl-acrylic acids prepn - from a ketone and glyoxylic acid (deriv)
DE2116293A1 (de) * 1971-04-02 1972-10-19 Cassella Farbwerke Mainkur Ag, 6000 Frankfurt Ketonderivate und Verfahren zu ihrer Herstellung
US3753997A (en) * 1971-06-07 1973-08-21 A Ash Trifluoromethly substituted-2,6-diphenyl-4-pyridyl carbinolamine antimalarials
US4017517A (en) * 1971-09-13 1977-04-12 Takeda Chemical Industries, Ltd. 2-(Trisubstituted benzoyl)-propionic acid and a method for the production thereof
BE788749A (fr) * 1971-09-13 1973-03-13 Takeda Chemical Industries Ltd Acide 3-(benzoyl trisubstitue)-propionique et son procede de preparation
BE795893A (fr) * 1972-02-28 1973-06-18 Unicler Derives de (methylene dioxy-3,4 phenyl)-1 dimethyl-4,4 pentene-1, leur preparation et leur application en therrapeutique
GB1392100A (en) * 1972-09-13 1975-04-23 Beecham Group Ltd Insecticides
FR2270856B1 (it) * 1974-01-17 1978-07-21 Screen
US3940404A (en) * 1974-03-06 1976-02-24 The United States Of America As Represented By The Secretary Of The Army 2-Substituted phenyl-6-trifluoromethyl-4-pyridyl-carbinolamines
US3953463A (en) * 1974-03-06 1976-04-27 The United States Of America As Represented By The Secretary Of The Army 2-Aryl-6-trifluoromethyl-4-pyridyl-carbinolamine antimalarials
IT1210582B (it) * 1981-10-22 1989-09-14 Roussel Maestretti Spa Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta'farmacologiche e composizioni farmaceutiche che li contengono
DE3228842A1 (de) * 1982-08-02 1984-02-02 Henkel Kgaa Sebosuppressive kosmetische mittel, enthaltend aryloxobutensaeurederivate sowie neue aryloxobutensaeurederivate

Also Published As

Publication number Publication date
EP0134179A3 (en) 1986-03-26
US4594443A (en) 1986-06-10
HUT34946A (en) 1985-05-28
ZA846107B (en) 1986-03-26
EP0134179A2 (fr) 1985-03-13
FI843354A0 (fi) 1984-08-24
JPS6072843A (ja) 1985-04-24
FI843354A (fi) 1985-02-26
FI79524B (fi) 1989-09-29
AU3235384A (en) 1985-02-28
AU565492B2 (en) 1987-09-17
IL72682A (en) 1987-10-20
HU191714B (en) 1987-03-30
KR850001724A (ko) 1985-04-01
FI79524C (fi) 1990-01-10
IL72682A0 (en) 1984-11-30
DE3474298D1 (en) 1988-11-03
EP0134179B1 (fr) 1988-09-28
SU1333233A3 (ru) 1987-08-23
CA1216859A (fr) 1987-01-20
PT78942A (fr) 1984-08-01
ES535411A0 (es) 1985-06-16
IT1169783B (it) 1987-06-03
MA20210A1 (fr) 1985-04-01
NZ209330A (en) 1987-09-30
ATE37533T1 (de) 1988-10-15
ES8505922A1 (es) 1985-06-16
PT78942B (fr) 1986-10-21
GR80172B (en) 1985-01-02

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