GR80172B - Process for the preparation of novel 4-phenyl 4-oxo buten-2-oic acid derivatives - Google Patents

Process for the preparation of novel 4-phenyl 4-oxo buten-2-oic acid derivatives

Info

Publication number
GR80172B
GR80172B GR80172A GR840180172A GR80172B GR 80172 B GR80172 B GR 80172B GR 80172 A GR80172 A GR 80172A GR 840180172 A GR840180172 A GR 840180172A GR 80172 B GR80172 B GR 80172B
Authority
GR
Greece
Prior art keywords
phenyl
novel
preparation
acid derivatives
oic acid
Prior art date
Application number
GR80172A
Other languages
English (en)
Inventor
Bianchi Maria
Bqrzachi Fernando
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of GR80172B publication Critical patent/GR80172B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/08Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738Esters of keto-carboxylic acids or aldehydo-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Detergent Compositions (AREA)
GR80172A 1983-08-25 1984-08-23 Process for the preparation of novel 4-phenyl 4-oxo buten-2-oic acid derivatives GR80172B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22648/83A IT1169783B (it) 1983-08-25 1983-08-25 Derivati dell' acido 4-fenil 4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali

Publications (1)

Publication Number Publication Date
GR80172B true GR80172B (en) 1985-01-02

Family

ID=11198831

Family Applications (1)

Application Number Title Priority Date Filing Date
GR80172A GR80172B (en) 1983-08-25 1984-08-23 Process for the preparation of novel 4-phenyl 4-oxo buten-2-oic acid derivatives

Country Status (19)

Country Link
US (1) US4594443A (el)
EP (1) EP0134179B1 (el)
JP (1) JPS6072843A (el)
KR (1) KR850001724A (el)
AT (1) ATE37533T1 (el)
AU (1) AU565492B2 (el)
CA (1) CA1216859A (el)
DE (1) DE3474298D1 (el)
ES (1) ES535411A0 (el)
FI (1) FI79524C (el)
GR (1) GR80172B (el)
HU (1) HU191714B (el)
IL (1) IL72682A (el)
IT (1) IT1169783B (el)
MA (1) MA20210A1 (el)
NZ (1) NZ209330A (el)
PT (1) PT78942B (el)
SU (1) SU1333233A3 (el)
ZA (1) ZA846107B (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190340B (it) * 1986-06-06 1988-02-16 Roussel Maestretti Spa Derivati dell'acido 4-fenil 4-osso 2-butenoico,loro procedimento di preparazione e loro impiego come prodotti medicinali
DK49688A (da) * 1987-03-20 1988-09-21 Hoffmann La Roche Propiolophenonderivater
HU198292B (en) * 1987-09-25 1989-09-28 Richter Gedeon Vegyeszet Process for producing salicilates and pharmaceutical compositions comprising such active ingredient
HU211731B (en) * 1992-12-29 1996-02-28 Richter Gedeon Vegyeszet Process to prepare novel salicylic acid derivs. and pharmaceutical compns. contg. them
KR960703901A (ko) * 1993-08-19 1996-08-31 로즈 암스트롱 치환된 2(5H)푸라논, 2(5H)티오페논 및 2(5H)피롤론 유도체, 그의 제조 방법 및 엔도텔린 길항제로서의 그의 용도(Substituted 2(5H)Furanone, 2(5H)Thiophenone and 2(5H)Pyrrolone Derivatives, Their Preparation and Their Use as Endothelin antagonists)
US5922759A (en) * 1996-06-21 1999-07-13 Warner-Lambert Company Butenolide endothelin antagonists
AU6603996A (en) * 1995-08-24 1997-03-19 Warner-Lambert Company Furanone endothelin antagonists
US5891892A (en) * 1996-10-29 1999-04-06 Warner-Lambert Company Small molecule biaryl compounds as inhibitors of endothelin converting enzyme
US20110067969A1 (en) * 2009-09-22 2011-03-24 Gm Global Technology Operations, Inc. Non-rotating clutch
PL3393530T3 (pl) * 2015-12-23 2022-12-05 Henkel Ag & Co. Kgaa Płyn do obróbki metali

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB588108A (en) * 1944-10-23 1947-05-14 Roche Products Ltd Manufacture of bacteriostatic substances
US2532579A (en) * 1946-08-06 1950-12-05 Du Pont Pest control compositions containing beta-acyl acrylates
US2562208A (en) * 1947-04-14 1951-07-31 Schering Corp Fungistatic composition
DE1282644B (de) * 1962-09-08 1968-11-14 Hoechst Ag Verfahren zur Herstellung von ungesaettigten ª€-Ketocarbonsaeureestern
DE2047806A1 (en) * 1970-09-29 1972-04-06 Dr Karl Thomae GmbH, 7950 Biberach 3-aroyl-acrylic acids - pharmaceutical intermediates prepd from acetophenones and glyoxylic acid derivs
DE2103749A1 (en) * 1971-01-27 1972-08-10 Dr. Karl Thomae GmbH, 7951 Biberach 3-acyl-acrylic acids prepn - from a ketone and glyoxylic acid (deriv)
DE2116293A1 (de) * 1971-04-02 1972-10-19 Cassella Farbwerke Mainkur Ag, 6000 Frankfurt Ketonderivate und Verfahren zu ihrer Herstellung
US3753997A (en) * 1971-06-07 1973-08-21 A Ash Trifluoromethly substituted-2,6-diphenyl-4-pyridyl carbinolamine antimalarials
US4017517A (en) * 1971-09-13 1977-04-12 Takeda Chemical Industries, Ltd. 2-(Trisubstituted benzoyl)-propionic acid and a method for the production thereof
BE788749A (fr) * 1971-09-13 1973-03-13 Takeda Chemical Industries Ltd Acide 3-(benzoyl trisubstitue)-propionique et son procede de preparation
BE795893A (fr) * 1972-02-28 1973-06-18 Unicler Derives de (methylene dioxy-3,4 phenyl)-1 dimethyl-4,4 pentene-1, leur preparation et leur application en therrapeutique
GB1392100A (en) * 1972-09-13 1975-04-23 Beecham Group Ltd Insecticides
FR2270856B1 (el) * 1974-01-17 1978-07-21 Screen
US3953463A (en) * 1974-03-06 1976-04-27 The United States Of America As Represented By The Secretary Of The Army 2-Aryl-6-trifluoromethyl-4-pyridyl-carbinolamine antimalarials
US3940404A (en) * 1974-03-06 1976-02-24 The United States Of America As Represented By The Secretary Of The Army 2-Substituted phenyl-6-trifluoromethyl-4-pyridyl-carbinolamines
IT1210582B (it) * 1981-10-22 1989-09-14 Roussel Maestretti Spa Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta'farmacologiche e composizioni farmaceutiche che li contengono
DE3228842A1 (de) * 1982-08-02 1984-02-02 Henkel Kgaa Sebosuppressive kosmetische mittel, enthaltend aryloxobutensaeurederivate sowie neue aryloxobutensaeurederivate

Also Published As

Publication number Publication date
PT78942B (fr) 1986-10-21
KR850001724A (ko) 1985-04-01
EP0134179A3 (en) 1986-03-26
NZ209330A (en) 1987-09-30
PT78942A (fr) 1984-08-01
EP0134179A2 (fr) 1985-03-13
FI79524B (fi) 1989-09-29
ES8505922A1 (es) 1985-06-16
HU191714B (en) 1987-03-30
JPS6072843A (ja) 1985-04-24
EP0134179B1 (fr) 1988-09-28
IT8322648A0 (it) 1983-08-25
DE3474298D1 (en) 1988-11-03
AU565492B2 (en) 1987-09-17
AU3235384A (en) 1985-02-28
FI843354A (fi) 1985-02-26
IT1169783B (it) 1987-06-03
US4594443A (en) 1986-06-10
IL72682A (en) 1987-10-20
IL72682A0 (en) 1984-11-30
ZA846107B (en) 1986-03-26
SU1333233A3 (ru) 1987-08-23
ATE37533T1 (de) 1988-10-15
FI843354A0 (fi) 1984-08-24
HUT34946A (en) 1985-05-28
ES535411A0 (es) 1985-06-16
MA20210A1 (fr) 1985-04-01
CA1216859A (fr) 1987-01-20
FI79524C (fi) 1990-01-10

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