ZA818240B - Substituted imidazolylphenyl amidines,processes for their preparation,and pharmaceutical compositions containing these - Google Patents

Substituted imidazolylphenyl amidines,processes for their preparation,and pharmaceutical compositions containing these

Info

Publication number
ZA818240B
ZA818240B ZA818240A ZA818240A ZA818240B ZA 818240 B ZA818240 B ZA 818240B ZA 818240 A ZA818240 A ZA 818240A ZA 818240 A ZA818240 A ZA 818240A ZA 818240 B ZA818240 B ZA 818240B
Authority
ZA
South Africa
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
substituted
Prior art date
Application number
ZA818240A
Other languages
English (en)
Inventor
Enzo Cereda
Arturo Donetti
Piero Del Soldato
Mario Bergamaschi
Original Assignee
Angeli Inst Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeli Inst Spa filed Critical Angeli Inst Spa
Publication of ZA818240B publication Critical patent/ZA818240B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA818240A 1980-11-28 1981-11-27 Substituted imidazolylphenyl amidines,processes for their preparation,and pharmaceutical compositions containing these ZA818240B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8026323A IT1209431B (it) 1980-11-28 1980-11-28 Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione.

Publications (1)

Publication Number Publication Date
ZA818240B true ZA818240B (en) 1983-07-27

Family

ID=11219229

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA818240A ZA818240B (en) 1980-11-28 1981-11-27 Substituted imidazolylphenyl amidines,processes for their preparation,and pharmaceutical compositions containing these

Country Status (30)

Country Link
US (2) US4386099A (cs)
EP (1) EP0053407B1 (cs)
JP (1) JPS57120575A (cs)
KR (1) KR880001317B1 (cs)
AR (1) AR228468A1 (cs)
AT (1) ATE24495T1 (cs)
AU (1) AU554592B2 (cs)
CA (1) CA1171092A (cs)
CS (2) CS249544B2 (cs)
DD (1) DD201893A5 (cs)
DE (2) DE3175754D1 (cs)
DK (1) DK157862C (cs)
ES (6) ES8207151A1 (cs)
FI (1) FI73209C (cs)
GB (1) GB2088375B (cs)
GR (1) GR77310B (cs)
HK (1) HK88186A (cs)
HU (1) HU187478B (cs)
IE (1) IE51946B1 (cs)
IL (1) IL64388A (cs)
IT (1) IT1209431B (cs)
MY (1) MY8700146A (cs)
NO (1) NO158183C (cs)
NZ (1) NZ199093A (cs)
PH (2) PH17390A (cs)
PL (2) PL135749B1 (cs)
PT (1) PT74048B (cs)
SU (2) SU1110381A3 (cs)
YU (2) YU42447B (cs)
ZA (1) ZA818240B (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1200371B (it) * 1982-03-24 1989-01-18 Angeli Inst Spa Guanidino eterociclifenilamidine,processi per la loro preparazione e loro impiego farmaceutico
IT1201523B (it) * 1982-05-18 1989-02-02 Angeli Inst Spa Eterociclilfenilfomramidine,processi per la loro preparazione e loro uso farmaceutico
IT1210914B (it) * 1982-07-29 1989-09-29 Angeli Inst Spa Eterociclilfenilsolfonil e fosfonilamidine sostituite, procedimento per la loro preparazione e loro uso farmaceutico.
IT1206498B (it) * 1983-07-18 1989-04-27 Angeli Inst Spa Derivati amidinici del4-fenilmidazolo 2-sostituto processi per la loro preparazione e loro uso farmaceutico.
IT1204910B (it) * 1987-01-28 1989-03-10 Angeli Inst Spa Composizioni farmaceutiche ad azione sinergica antisecretoria per la cicatrizzazione dell'ulcera gastroduodenale
KR920004935B1 (ko) * 1990-07-12 1992-06-22 일양약품공업 주식회사 N-디메톡시 페닐알킬-n'-이미다졸릴페닐 아미딘 유도체 및 그의 제조방법
US5294433A (en) * 1992-04-15 1994-03-15 The Procter & Gamble Company Use of H-2 antagonists for treatment of gingivitis
TW460460B (en) 1997-11-04 2001-10-21 Chugai Pharmaceutical Co Ltd Heterocyclic compounds having NOS inhibitory activities
CN1250209C (zh) * 1999-11-01 2006-04-12 大正制药株式会社 20-羟基二十碳四烯酸合成酶抑制剂
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1579862A1 (en) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
US20080045575A1 (en) * 2004-12-29 2008-02-21 Van Dyke Thomas E Delivery of H2 Antagonists
WO2007031513A1 (en) * 2005-09-13 2007-03-22 Bayer Cropscience Ag Pesticide thiazolyloxy substituted phenylamidine derivatives
EP1920785A1 (en) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
EP2825159B1 (en) 2012-03-15 2022-06-22 Boehringer Ingelheim Vetmedica GmbH Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof
MX2016000727A (es) 2013-07-19 2016-04-13 Boehringer Ingelheim Vetmed Composicion farmaceutica acuosa liquida que contiene derivados de ciclodextrina eterificada con conservante.
HUE056143T2 (hu) 2013-12-04 2024-01-28 Boehringer Ingelheim Vetmedica Gmbh Pimobendán javított gyógyászati készítményei
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069340A (en) * 1976-01-30 1978-01-17 Hooker Chemicals & Plastics Corporation Immonium salts and derivatives thereof
DE2645477C2 (de) * 1976-10-08 1982-03-04 Dynamit Nobel Ag, 5210 Troisdorf Verfahren zur Herstellung von Orthoessigsäurealkylestern
US4225724A (en) * 1977-01-07 1980-09-30 Westwood Pharmaceuticals, Inc. 1-(2-Phenylureylene)imidazoles
US4236015A (en) * 1977-01-07 1980-11-25 Westwood Pharmaceuticals, Inc. 1-(2-Acylaminophenyl)imidazoles
US4160097A (en) * 1977-01-07 1979-07-03 Westwind Pharmaceuticals, Inc. 1-(2-Phenylureylene)imidazoles

Also Published As

Publication number Publication date
ATE24495T1 (de) 1987-01-15
GB2088375B (en) 1985-01-09
JPH0233031B2 (cs) 1990-07-25
PL234007A1 (en) 1983-03-14
MY8700146A (en) 1987-12-31
SU1110382A3 (ru) 1984-08-23
ES507508A0 (es) 1982-09-01
ES507509A0 (es) 1982-09-01
IE812790L (en) 1982-05-28
ES507501A0 (es) 1982-09-01
IL64388A (en) 1985-04-30
GB2088375A (en) 1982-06-09
CS249544B2 (en) 1987-03-12
AU7794781A (en) 1982-06-03
NZ199093A (en) 1985-05-31
IT1209431B (it) 1989-07-16
AR228468A1 (es) 1983-03-15
EP0053407A3 (en) 1983-07-27
PT74048B (en) 1983-12-07
EP0053407A2 (en) 1982-06-09
ES8207148A1 (es) 1982-09-01
FI73209B (fi) 1987-05-29
YU175983A (en) 1984-06-30
US4465841A (en) 1984-08-14
YU278081A (en) 1984-06-30
ES8207150A1 (es) 1982-09-01
YU42878B (en) 1988-12-31
DD201893A5 (de) 1983-08-17
IE51946B1 (en) 1987-04-29
PL136015B1 (en) 1986-01-31
KR880001317B1 (ko) 1988-07-23
ES8207151A1 (es) 1982-09-01
GR77310B (cs) 1984-09-11
DE53407T1 (de) 1983-01-20
PT74048A (en) 1981-12-01
US4386099A (en) 1983-05-31
DK157862B (da) 1990-02-26
YU42447B (en) 1988-08-31
IT8026323A0 (it) 1980-11-28
ES8207152A1 (es) 1982-09-01
DK525581A (da) 1982-05-29
ES8207149A1 (es) 1982-09-01
PH17390A (en) 1984-08-08
NO158183C (no) 1988-07-27
PL238422A1 (en) 1983-06-06
PH19032A (en) 1985-12-06
KR830007575A (ko) 1983-11-04
FI73209C (fi) 1987-09-10
CA1171092A (en) 1984-07-17
ES8207147A1 (es) 1982-09-01
NO814065L (no) 1982-06-01
AU554592B2 (en) 1986-08-28
IL64388A0 (en) 1982-02-28
JPS57120575A (en) 1982-07-27
NO158183B (no) 1988-04-18
DE3175754D1 (en) 1987-02-05
HU187478B (en) 1986-01-28
EP0053407B1 (en) 1986-12-30
HK88186A (en) 1986-11-28
PL135749B1 (en) 1985-12-31
ES507506A0 (es) 1982-09-01
DK157862C (da) 1990-08-06
ES507505A0 (es) 1982-09-01
SU1110381A3 (ru) 1984-08-23
FI813794L (fi) 1982-05-29
ES507507A0 (es) 1982-09-01
CS249115B2 (en) 1987-03-12

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