ZA80523B - Crystalline 3-hydroxycephalosporin solvates - Google Patents

Crystalline 3-hydroxycephalosporin solvates

Info

Publication number
ZA80523B
ZA80523B ZA00800523A ZA80523A ZA80523B ZA 80523 B ZA80523 B ZA 80523B ZA 00800523 A ZA00800523 A ZA 00800523A ZA 80523 A ZA80523 A ZA 80523A ZA 80523 B ZA80523 B ZA 80523B
Authority
ZA
South Africa
Prior art keywords
hydroxycephalosporin
solvates
crystalline
hydroxycephalosporin solvates
Prior art date
Application number
ZA00800523A
Other languages
English (en)
Inventor
J Fisher
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA80523B publication Critical patent/ZA80523B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/30—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino-radical acylated by an araliphatic carboxylic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA00800523A 1979-02-01 1980-01-29 Crystalline 3-hydroxycephalosporin solvates ZA80523B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US846879A 1979-02-01 1979-02-01

Publications (1)

Publication Number Publication Date
ZA80523B true ZA80523B (en) 1981-09-30

Family

ID=21731772

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00800523A ZA80523B (en) 1979-02-01 1980-01-29 Crystalline 3-hydroxycephalosporin solvates

Country Status (32)

Country Link
EP (1) EP0014565B1 (bs)
JP (1) JPS55104288A (bs)
KR (1) KR830001890B1 (bs)
AR (1) AR228342A1 (bs)
AT (1) AT366052B (bs)
AU (1) AU532573B2 (bs)
BE (1) BE881423A (bs)
BG (1) BG32857A3 (bs)
CA (1) CA1142173A (bs)
CH (1) CH647525A5 (bs)
CS (1) CS214694B2 (bs)
DD (1) DD148953A5 (bs)
DE (1) DE3062095D1 (bs)
DK (1) DK159157C (bs)
ES (1) ES488229A0 (bs)
FI (1) FI68239C (bs)
FR (1) FR2447925A1 (bs)
GB (1) GB2041934B (bs)
GR (1) GR72785B (bs)
HU (2) HU181761B (bs)
IE (1) IE49374B1 (bs)
IL (1) IL59265A (bs)
IT (1) IT1130239B (bs)
LU (1) LU82118A1 (bs)
NZ (1) NZ192750A (bs)
PH (1) PH15152A (bs)
PL (1) PL122609B1 (bs)
PT (1) PT70742A (bs)
RO (2) RO83702B (bs)
SU (2) SU897109A3 (bs)
YU (1) YU22480A (bs)
ZA (1) ZA80523B (bs)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4548894A (en) * 1981-07-22 1985-10-22 Basf Aktiengesellschaft Photosensitive recording materials for the production of abrasion-resistant and scratch-resistant gravure printing plates comprising particles

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6011491A (ja) * 1983-03-04 1985-01-21 Shionogi & Co Ltd セフアロチンナトリウムの結晶性凍結乾燥粉末の製造法
US4782144A (en) * 1987-09-14 1988-11-01 Eli Lilly And Company 1-carba(dethia)-3-hydroxy-3-cephem ester crystalline and crystalline solvate thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985747A (en) * 1974-05-24 1976-10-12 Bristol-Myers Company Crystalline sesquihydrate of 7-[D-α-amino-α-(p-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
US4044002A (en) * 1976-06-09 1977-08-23 Eli Lilly And Company Reduction process for cephalosporin sulfoxides

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4548894A (en) * 1981-07-22 1985-10-22 Basf Aktiengesellschaft Photosensitive recording materials for the production of abrasion-resistant and scratch-resistant gravure printing plates comprising particles

Also Published As

Publication number Publication date
AR228342A1 (es) 1983-02-28
DK159157B (da) 1990-09-10
ES8103098A1 (es) 1981-02-16
JPS55104288A (en) 1980-08-09
HU182095B (en) 1983-12-28
SU897109A3 (ru) 1982-01-07
KR830001951A (ko) 1983-05-21
IT1130239B (it) 1986-06-11
DK159157C (da) 1991-02-11
ATA49980A (de) 1981-07-15
EP0014565B1 (en) 1983-02-23
RO83702B (ro) 1984-03-30
IL59265A0 (en) 1980-05-30
FR2447925A1 (fr) 1980-08-29
SU938740A3 (ru) 1982-06-23
NZ192750A (en) 1982-05-25
AT366052B (de) 1982-03-10
AU5502680A (en) 1980-08-07
DD148953A5 (de) 1981-06-17
PT70742A (en) 1980-02-01
CS214694B2 (en) 1982-05-28
FI68239C (fi) 1985-08-12
IL59265A (en) 1983-05-15
FI800300A (fi) 1980-08-02
IT8019607A0 (it) 1980-01-31
EP0014565A1 (en) 1980-08-20
LU82118A1 (fr) 1980-04-23
DK41180A (da) 1980-08-02
RO79181A (ro) 1982-06-25
FI68239B (fi) 1985-04-30
IE49374B1 (en) 1985-09-18
IE800191L (en) 1980-08-01
ES488229A0 (es) 1981-02-16
GR72785B (bs) 1983-12-05
YU22480A (en) 1983-02-28
BG32857A3 (en) 1982-10-15
GB2041934B (en) 1983-03-23
FR2447925B1 (bs) 1984-02-03
GB2041934A (en) 1980-09-17
HU181761B (en) 1983-11-28
PL221748A1 (bs) 1980-12-15
PH15152A (en) 1982-08-24
PL122609B1 (en) 1982-08-31
AU532573B2 (en) 1983-10-06
BE881423A (fr) 1980-07-30
KR830001890B1 (ko) 1983-09-17
CH647525A5 (fr) 1985-01-31
RO83702A (ro) 1984-03-15
DE3062095D1 (en) 1983-03-31
JPH0128035B2 (bs) 1989-05-31
CA1142173A (en) 1983-03-01

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