ZA803867B - Halogenated derivative of the 16a-methyl pregnane series, its preparation, its application as a medicament and the compositions containing it - Google Patents

Halogenated derivative of the 16a-methyl pregnane series, its preparation, its application as a medicament and the compositions containing it

Info

Publication number
ZA803867B
ZA803867B ZA00803867A ZA803867A ZA803867B ZA 803867 B ZA803867 B ZA 803867B ZA 00803867 A ZA00803867 A ZA 00803867A ZA 803867 A ZA803867 A ZA 803867A ZA 803867 B ZA803867 B ZA 803867B
Authority
ZA
South Africa
Prior art keywords
medicament
preparation
application
compositions containing
halogenated derivative
Prior art date
Application number
ZA00803867A
Other languages
English (en)
Inventor
J Teutsch
R Deraedt
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA803867B publication Critical patent/ZA803867B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA00803867A 1979-07-26 1980-06-26 Halogenated derivative of the 16a-methyl pregnane series, its preparation, its application as a medicament and the compositions containing it ZA803867B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7919296A FR2462443A1 (fr) 1979-07-26 1979-07-26 Nouveau derive halogene de la serie du 16a-methyl pregnane, son procede de preparation et son application comme medicament

Publications (1)

Publication Number Publication Date
ZA803867B true ZA803867B (en) 1981-06-24

Family

ID=9228325

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00803867A ZA803867B (en) 1979-07-26 1980-06-26 Halogenated derivative of the 16a-methyl pregnane series, its preparation, its application as a medicament and the compositions containing it

Country Status (20)

Country Link
US (1) US4353899A (zh)
JP (1) JPS5622798A (zh)
AT (1) AT371483B (zh)
AU (1) AU528292B2 (zh)
BE (1) BE884494A (zh)
CA (1) CA1141751A (zh)
CH (1) CH645389A5 (zh)
DE (1) DE3028255C2 (zh)
DK (1) DK146690C (zh)
FI (1) FI66880C (zh)
FR (1) FR2462443A1 (zh)
GB (1) GB2054600B (zh)
HU (1) HU180364B (zh)
IE (1) IE50031B1 (zh)
IT (1) IT1145302B (zh)
MX (1) MX6649E (zh)
NL (1) NL8004282A (zh)
NO (1) NO153102C (zh)
SE (1) SE447387B (zh)
ZA (1) ZA803867B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2533928A1 (fr) * 1982-10-05 1984-04-06 Roussel Uclaf Nouveaux derives dichlores de la serie du 16a-methyl pregnane, leur procede de preparation et leur application comme medicaments
FR2561919B1 (fr) * 1984-04-03 1986-12-19 Roussel Uclaf Composition pharmaceutique constituee d'une part, a titre de principe actif, par la 9a,11b-dichloro 16a-methyl 21-oxycarbonyldicyclohexyl methyloxy pregna-1,4-diene 3,20-dione et d'autre part, par un excipient pharmaceutique inerte apte a permettre l'action du produit dans le rectum ou le colon
DE19932511A1 (de) * 1999-07-12 2001-01-18 Helmig Hans Gmbh Schaltvorrichtung für eine Kettengangschaltung zur Betätigung der Kettenradgruppe an der Tretkurbel eines Fahrrades

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL122815C (zh) * 1963-12-19
FR2342738A1 (fr) * 1976-03-02 1977-09-30 Roussel Uclaf Nouveaux derives halogenes de la serie du 16a-methyl pregnane
FR2381065A2 (fr) * 1977-02-22 1978-09-15 Roussel Uclaf Nouveaux derives halogenes de la serie du 16 a-methyl pregnane

Also Published As

Publication number Publication date
AT371483B (de) 1983-06-27
US4353899A (en) 1982-10-12
SE8004428L (sv) 1981-01-27
IE50031B1 (en) 1986-02-05
BE884494A (fr) 1981-01-26
FR2462443B1 (zh) 1982-12-31
FI802092A (fi) 1981-01-27
DK146690B (da) 1983-12-05
SE447387B (sv) 1986-11-10
IT1145302B (it) 1986-11-05
DE3028255C2 (de) 1985-12-19
FI66880C (fi) 1984-12-10
CH645389A5 (fr) 1984-09-28
CA1141751A (fr) 1983-02-22
NO802256L (no) 1981-01-27
IT8049248A0 (it) 1980-07-15
IE801561L (en) 1981-01-26
DK321180A (da) 1981-01-27
AU6081180A (en) 1981-01-29
MX6649E (es) 1985-10-01
NO153102B (no) 1985-10-07
JPS5622798A (en) 1981-03-03
GB2054600A (en) 1981-02-18
FR2462443A1 (fr) 1981-02-13
ATA391380A (de) 1982-11-15
HU180364B (en) 1983-02-28
DE3028255A1 (de) 1981-02-19
NO153102C (no) 1986-01-15
NL8004282A (nl) 1981-01-28
DK146690C (da) 1984-05-21
GB2054600B (en) 1983-02-02
FI66880B (fi) 1984-08-31
AU528292B2 (en) 1983-04-21
JPS6254438B2 (zh) 1987-11-14

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