ZA794379B - Novel spiro-oxazolidindiones - Google Patents

Novel spiro-oxazolidindiones

Info

Publication number
ZA794379B
ZA794379B ZA00794379A ZA794379A ZA794379B ZA 794379 B ZA794379 B ZA 794379B ZA 00794379 A ZA00794379 A ZA 00794379A ZA 794379 A ZA794379 A ZA 794379A ZA 794379 B ZA794379 B ZA 794379B
Authority
ZA
South Africa
Prior art keywords
oxazolidindiones
novel spiro
spiro
novel
Prior art date
Application number
ZA00794379A
Other languages
English (en)
Inventor
R Schnur
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA794379B publication Critical patent/ZA794379B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Photosensitive Polymer And Photoresist Processing (AREA)
  • Moulding By Coating Moulds (AREA)
  • Dental Preparations (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA00794379A 1978-08-21 1979-08-20 Novel spiro-oxazolidindiones ZA794379B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/935,199 US4200642A (en) 1978-08-21 1978-08-21 Spiro-oxazolidindiones

Publications (1)

Publication Number Publication Date
ZA794379B true ZA794379B (en) 1980-08-27

Family

ID=25466700

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00794379A ZA794379B (en) 1978-08-21 1979-08-20 Novel spiro-oxazolidindiones

Country Status (34)

Country Link
US (1) US4200642A (cg-RX-API-DMAC7.html)
JP (4) JPS6011914B2 (cg-RX-API-DMAC7.html)
AR (1) AR225614A1 (cg-RX-API-DMAC7.html)
AT (1) AT366689B (cg-RX-API-DMAC7.html)
AU (1) AU535170B2 (cg-RX-API-DMAC7.html)
BE (1) BE878311A (cg-RX-API-DMAC7.html)
CA (1) CA1121361A (cg-RX-API-DMAC7.html)
CH (1) CH639974A5 (cg-RX-API-DMAC7.html)
CS (1) CS208129B2 (cg-RX-API-DMAC7.html)
DD (1) DD146602A5 (cg-RX-API-DMAC7.html)
DE (2) DE2933441C2 (cg-RX-API-DMAC7.html)
DK (1) DK258479A (cg-RX-API-DMAC7.html)
EG (1) EG14639A (cg-RX-API-DMAC7.html)
ES (1) ES483511A1 (cg-RX-API-DMAC7.html)
FI (1) FI65255C (cg-RX-API-DMAC7.html)
FR (3) FR2442851A1 (cg-RX-API-DMAC7.html)
GB (2) GB2028318B (cg-RX-API-DMAC7.html)
GR (1) GR71913B (cg-RX-API-DMAC7.html)
HU (1) HU179746B (cg-RX-API-DMAC7.html)
IE (1) IE48932B1 (cg-RX-API-DMAC7.html)
IL (1) IL58076A (cg-RX-API-DMAC7.html)
IN (1) IN152416B (cg-RX-API-DMAC7.html)
IT (1) IT1123536B (cg-RX-API-DMAC7.html)
LU (1) LU81613A1 (cg-RX-API-DMAC7.html)
NL (1) NL7906318A (cg-RX-API-DMAC7.html)
NO (1) NO792699L (cg-RX-API-DMAC7.html)
NZ (1) NZ191350A (cg-RX-API-DMAC7.html)
PH (1) PH18091A (cg-RX-API-DMAC7.html)
PL (1) PL130686B1 (cg-RX-API-DMAC7.html)
PT (1) PT70086A (cg-RX-API-DMAC7.html)
SE (1) SE447116B (cg-RX-API-DMAC7.html)
SU (1) SU942597A3 (cg-RX-API-DMAC7.html)
YU (1) YU41488B (cg-RX-API-DMAC7.html)
ZA (1) ZA794379B (cg-RX-API-DMAC7.html)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329459A (en) * 1980-05-05 1982-05-11 The Upjohn Company Tetrahydrobenzopyran derivatives
GB2080803B (en) * 1980-07-28 1984-01-18 Pfizer Hypoglycemic 5-substituted oxazolidine-2,4-diones
US4367234A (en) * 1980-07-28 1983-01-04 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones
ES515751A0 (es) * 1981-10-13 1983-10-16 Pfizer "un procedimiento por analogia para la preparacion de derivados de espiro-oxindol-oxazolidindiona".
US4464385A (en) * 1982-04-15 1984-08-07 Alcon Laboratories, Inc. Treatment of diabetic complications with hydantoins
US4436745A (en) 1982-04-15 1984-03-13 Alcon Laboratories, Inc. Method of inhibiting aldose reductase activity
US4438272A (en) 1982-04-15 1984-03-20 Alcon Laboratories, Inc. Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones
US4540700A (en) * 1982-04-15 1985-09-10 Alcon Laboratories, Inc. Treatment of diabetic complications with certain spiro-imidazolidine-diones
ZA832679B (en) * 1982-05-07 1983-12-28 Ici Plc Indoline derivatives
US4430337A (en) * 1982-06-23 1984-02-07 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
US4556670A (en) * 1982-12-06 1985-12-03 Pfizer Inc. Spiro-3-hetero-azolones for treatment of diabetic complications
US4533667A (en) * 1983-05-25 1985-08-06 Pfizer Inc. Imidazolidinedione derivatives
US4464380A (en) * 1983-05-25 1984-08-07 Pfizer Inc. Imidazolidinedione derivatives
DK277484A (da) * 1983-06-23 1984-12-24 Hoffmann La Roche Thiazolidinderivater
JPS61200991A (ja) * 1985-03-04 1986-09-05 Sanwa Kagaku Kenkyusho:Kk スピロ―３―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤
DE3522791C1 (en) * 1985-06-26 1987-01-02 Ferroplast Gmbh Positioning wall for lagging a cavity to be filled with a hardenable material in mining or tunnelling
WO1987004344A1 (en) * 1986-01-17 1987-07-30 Pfizer Inc. Hydroxyacetic acid derivatives for the treatment of diabetic complications
US5039672A (en) * 1990-04-05 1991-08-13 Pfizer Inc. Heterocyclic compounds as aldose reductase inhibitors
US5068332A (en) * 1990-10-12 1991-11-26 American Home Products Corporation Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
US5102886A (en) * 1990-10-12 1992-04-07 American Home Products Corporation 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones and analogs thereof useful as aldose reductase inhibitors
FR2707981B1 (fr) * 1993-07-20 1995-09-01 Adir Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2725206B1 (fr) * 1994-09-29 1996-12-06 Roussel Uclaf Nouvelles imidazolidines substituees par un heterocycle, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
JP2003502369A (ja) 1999-06-18 2003-01-21 メルク エンド カムパニー インコーポレーテッド アリールチアゾリジンジオン誘導体およびアリールオキサゾリジンジオン誘導体
US6380191B1 (en) 1999-06-18 2002-04-30 Merck & Co. Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
ITPI20060083A1 (it) * 2006-07-11 2008-01-12 Univ Pisa Derivati 2,2-dimetilcromanici 4-spiro-eterocicilici azotati (a 5 e 6 termini) n-sostituiti quali cardio-protettori nei confronti dell'insulto ischemico
USD775790S1 (en) * 2015-11-18 2017-01-10 Ginger Damon Motorcycle jacket
CN111465377A (zh) 2017-12-21 2020-07-28 易希提卫生与保健公司 包括强壮的通道密封结合的吸收性物品
MY196715A (en) 2017-12-21 2023-05-02 Essity Hygiene & Health Ab Absorbent article and method for manufacturing an absorbent article
AU2022265392B2 (en) * 2021-04-30 2025-09-04 Grand Pharma (China) Co., Ltd. Method and pharmaceutical composition for treating myopia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1204232B (de) * 1959-07-16 1965-11-04 Ncr Co Verfahren zur Herstellung von Derivaten von 3-Alkyl-3'-methyl-spiro[benzoxazolin-2, 2'-(2'H-1'-benzopyran)]
US3532744A (en) * 1967-07-28 1970-10-06 American Home Prod 1- and 2-amino substituted indane and tetralene carboxylic acids
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
CA1088945A (en) * 1976-10-18 1980-11-04 Pfizer Limited Hydantoin derivatives as therapeutic agents

Also Published As

Publication number Publication date
ES483511A1 (es) 1980-09-01
IL58076A0 (en) 1979-12-30
NO792699L (no) 1980-02-22
JPS5946517B2 (ja) 1984-11-13
FR2440949A1 (fr) 1980-06-06
ATA560579A (de) 1981-09-15
IL58076A (en) 1982-07-30
IN152416B (cg-RX-API-DMAC7.html) 1984-01-07
JPS6011914B2 (ja) 1985-03-28
PH18091A (en) 1985-03-20
FR2442851A1 (fr) 1980-06-27
GR71913B (cg-RX-API-DMAC7.html) 1983-08-16
DE2953954A1 (cg-RX-API-DMAC7.html) 1982-09-02
CS208129B2 (en) 1981-08-31
PL217881A1 (cg-RX-API-DMAC7.html) 1981-01-02
JPS55129280A (en) 1980-10-06
FI65255C (fi) 1984-04-10
IT1123536B (it) 1986-04-30
JPS55129279A (en) 1980-10-06
DD146602A5 (de) 1981-02-18
CH639974A5 (fr) 1983-12-15
SE7906949L (sv) 1980-02-22
IE791592L (en) 1980-02-21
BE878311A (fr) 1980-02-20
FR2440950B1 (cg-RX-API-DMAC7.html) 1981-06-12
FR2442851B1 (cg-RX-API-DMAC7.html) 1983-06-17
SE447116B (sv) 1986-10-27
DE2933441A1 (de) 1980-02-28
AU535170B2 (en) 1984-03-08
FR2440950A1 (fr) 1980-06-06
CA1121361A (en) 1982-04-06
DE2953954C2 (cg-RX-API-DMAC7.html) 1987-12-03
JPS5528996A (en) 1980-02-29
GB2028318A (en) 1980-03-05
GB2033904B (en) 1982-08-04
HU179746B (en) 1982-12-28
EG14639A (en) 1985-03-31
YU41488B (en) 1987-08-31
IE48932B1 (en) 1985-06-26
PT70086A (en) 1979-09-01
JPS55129288A (en) 1980-10-06
NZ191350A (en) 1984-04-27
FR2440949B1 (cg-RX-API-DMAC7.html) 1981-06-12
AT366689B (de) 1982-04-26
IT7925182A0 (it) 1979-08-20
GB2033904A (en) 1980-05-29
DK258479A (da) 1980-02-22
JPS6011915B2 (ja) 1985-03-28
LU81613A1 (fr) 1980-04-21
AU5009279A (en) 1980-02-28
AR225614A1 (es) 1982-04-15
FI792567A7 (fi) 1980-02-22
NL7906318A (nl) 1980-02-25
PL130686B1 (en) 1984-08-31
US4200642A (en) 1980-04-29
SU942597A3 (ru) 1982-07-07
DE2933441C2 (de) 1987-04-23
FI65255B (fi) 1983-12-30
YU199979A (en) 1983-06-30
JPS5943954B2 (ja) 1984-10-25
GB2028318B (en) 1982-08-04

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