ZA794379B - Novel spiro-oxazolidindiones - Google Patents

Novel spiro-oxazolidindiones

Info

Publication number
ZA794379B
ZA794379B ZA00794379A ZA794379A ZA794379B ZA 794379 B ZA794379 B ZA 794379B ZA 00794379 A ZA00794379 A ZA 00794379A ZA 794379 A ZA794379 A ZA 794379A ZA 794379 B ZA794379 B ZA 794379B
Authority
ZA
South Africa
Prior art keywords
oxazolidindiones
novel spiro
spiro
novel
Prior art date
Application number
ZA00794379A
Other languages
English (en)
Inventor
R Schnur
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA794379B publication Critical patent/ZA794379B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Photosensitive Polymer And Photoresist Processing (AREA)
  • Moulding By Coating Moulds (AREA)
  • Dental Preparations (AREA)
ZA00794379A 1978-08-21 1979-08-20 Novel spiro-oxazolidindiones ZA794379B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/935,199 US4200642A (en) 1978-08-21 1978-08-21 Spiro-oxazolidindiones

Publications (1)

Publication Number Publication Date
ZA794379B true ZA794379B (en) 1980-08-27

Family

ID=25466700

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00794379A ZA794379B (en) 1978-08-21 1979-08-20 Novel spiro-oxazolidindiones

Country Status (34)

Country Link
US (1) US4200642A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (4) JPS6011914B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR225614A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT366689B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU535170B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE878311A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1121361A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH639974A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS208129B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD146602A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE2933441C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK258479A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EG (1) EG14639A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES483511A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI65255C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (3) FR2442851A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (2) GB2028318B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR71913B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU179746B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE48932B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL58076A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN152416B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1123536B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (1) LU81613A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7906318A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO792699L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ191350A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH18091A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL130686B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT70086A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE447116B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU942597A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU41488B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA794379B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329459A (en) * 1980-05-05 1982-05-11 The Upjohn Company Tetrahydrobenzopyran derivatives
SG56656G (en) * 1980-07-28 1987-03-27 Pfizer Hypoglycemic 5-substituted oxazolidine-2, 4-diones
US4367234A (en) * 1980-07-28 1983-01-04 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones
ES8400116A1 (es) * 1981-10-13 1983-10-16 Pfizer "un procedimiento por analogia para la preparacion de derivados de espiro-oxindol-oxazolidindiona".
US4436745A (en) 1982-04-15 1984-03-13 Alcon Laboratories, Inc. Method of inhibiting aldose reductase activity
US4540700A (en) * 1982-04-15 1985-09-10 Alcon Laboratories, Inc. Treatment of diabetic complications with certain spiro-imidazolidine-diones
US4464385A (en) * 1982-04-15 1984-08-07 Alcon Laboratories, Inc. Treatment of diabetic complications with hydantoins
US4438272A (en) 1982-04-15 1984-03-20 Alcon Laboratories, Inc. Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones
ZA832679B (en) * 1982-05-07 1983-12-28 Ici Plc Indoline derivatives
US4430337A (en) 1982-06-23 1984-02-07 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
US4556670A (en) * 1982-12-06 1985-12-03 Pfizer Inc. Spiro-3-hetero-azolones for treatment of diabetic complications
US4533667A (en) * 1983-05-25 1985-08-06 Pfizer Inc. Imidazolidinedione derivatives
US4464380A (en) * 1983-05-25 1984-08-07 Pfizer Inc. Imidazolidinedione derivatives
DK277484A (da) * 1983-06-23 1984-12-24 Hoffmann La Roche Thiazolidinderivater
JPS61200991A (ja) * 1985-03-04 1986-09-05 Sanwa Kagaku Kenkyusho:Kk スピロ―3―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤
DE3522791C1 (en) * 1985-06-26 1987-01-02 Ferroplast Gmbh Positioning wall for lagging a cavity to be filled with a hardenable material in mining or tunnelling
US4853410A (en) * 1986-01-17 1989-08-01 Pfizer Inc. Hydroxyacetic acid derivatives for the treatment of diabetic complications
US5039672A (en) * 1990-04-05 1991-08-13 Pfizer Inc. Heterocyclic compounds as aldose reductase inhibitors
US5068332A (en) * 1990-10-12 1991-11-26 American Home Products Corporation Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
US5102886A (en) * 1990-10-12 1992-04-07 American Home Products Corporation 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones and analogs thereof useful as aldose reductase inhibitors
FR2707981B1 (fr) * 1993-07-20 1995-09-01 Adir Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2725206B1 (fr) * 1994-09-29 1996-12-06 Roussel Uclaf Nouvelles imidazolidines substituees par un heterocycle, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
CA2376919C (en) 1999-06-18 2008-11-04 Merck & Co., Inc. Arylthiazolidinedione and aryloxazolidinedione derivatives
JP2003502370A (ja) 1999-06-18 2003-01-21 メルク エンド カムパニー インコーポレーテッド アリールチアゾリジンジオン誘導体およびアリールオキサゾリジンジオン誘導体
ITPI20060083A1 (it) * 2006-07-11 2008-01-12 Univ Pisa Derivati 2,2-dimetilcromanici 4-spiro-eterocicilici azotati (a 5 e 6 termini) n-sostituiti quali cardio-protettori nei confronti dell'insulto ischemico
USD775790S1 (en) * 2015-11-18 2017-01-10 Ginger Damon Motorcycle jacket
BR112020008382A2 (pt) 2017-12-21 2020-11-03 Essity Hygiene And Health Aktiebolag artigo absorvente com vedações de canal e método para a fabricação do artigo absorvente
RU2020123382A (ru) 2017-12-21 2022-01-21 Эссити Хайджин Энд Хелт Актиеболаг Впитывающее изделие и способ изготовления впитывающего изделия
JP2024517782A (ja) * 2021-04-30 2024-04-23 ▲遠▼大医▲薬▼(中国)有限公司 近視を治療するための方法及び薬物組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1204232B (de) * 1959-07-16 1965-11-04 Ncr Co Verfahren zur Herstellung von Derivaten von 3-Alkyl-3'-methyl-spiro[benzoxazolin-2, 2'-(2'H-1'-benzopyran)]
US3532744A (en) * 1967-07-28 1970-10-06 American Home Prod 1- and 2-amino substituted indane and tetralene carboxylic acids
US3821383A (en) * 1972-07-10 1974-06-28 Ayerst Mckenna & Harrison Compositions for and a method of treating diabetic complications
CA1088945A (en) * 1976-10-18 1980-11-04 Pfizer Limited Hydantoin derivatives as therapeutic agents

Also Published As

Publication number Publication date
HU179746B (en) 1982-12-28
IE791592L (en) 1980-02-21
JPS6011915B2 (ja) 1985-03-28
DD146602A5 (de) 1981-02-18
JPS6011914B2 (ja) 1985-03-28
US4200642A (en) 1980-04-29
GB2028318A (en) 1980-03-05
DE2933441C2 (de) 1987-04-23
YU41488B (en) 1987-08-31
NO792699L (no) 1980-02-22
FR2442851B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-06-17
PL130686B1 (en) 1984-08-31
FI792567A7 (fi) 1980-02-22
PL217881A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-01-02
JPS5943954B2 (ja) 1984-10-25
IL58076A0 (en) 1979-12-30
NZ191350A (en) 1984-04-27
IL58076A (en) 1982-07-30
CH639974A5 (fr) 1983-12-15
BE878311A (fr) 1980-02-20
SE7906949L (sv) 1980-02-22
DE2953954C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-12-03
LU81613A1 (fr) 1980-04-21
GB2033904A (en) 1980-05-29
IT1123536B (it) 1986-04-30
FR2440950A1 (fr) 1980-06-06
NL7906318A (nl) 1980-02-25
JPS55129280A (en) 1980-10-06
YU199979A (en) 1983-06-30
ES483511A1 (es) 1980-09-01
EG14639A (en) 1985-03-31
CA1121361A (en) 1982-04-06
AU5009279A (en) 1980-02-28
AU535170B2 (en) 1984-03-08
AR225614A1 (es) 1982-04-15
CS208129B2 (en) 1981-08-31
JPS5528996A (en) 1980-02-29
FR2442851A1 (fr) 1980-06-27
DK258479A (da) 1980-02-22
GB2033904B (en) 1982-08-04
SU942597A3 (ru) 1982-07-07
GR71913B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1983-08-16
SE447116B (sv) 1986-10-27
AT366689B (de) 1982-04-26
FI65255C (fi) 1984-04-10
FR2440949B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-06-12
JPS55129279A (en) 1980-10-06
IT7925182A0 (it) 1979-08-20
IE48932B1 (en) 1985-06-26
ATA560579A (de) 1981-09-15
PH18091A (en) 1985-03-20
DE2953954A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1982-09-02
PT70086A (en) 1979-09-01
IN152416B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-01-07
DE2933441A1 (de) 1980-02-28
FR2440949A1 (fr) 1980-06-06
GB2028318B (en) 1982-08-04
FI65255B (fi) 1983-12-30
FR2440950B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-06-12
JPS55129288A (en) 1980-10-06
JPS5946517B2 (ja) 1984-11-13

Similar Documents

Publication Publication Date Title
EG13913A (en) Novel n-heterocyclyl-4-piperidinamines
GB2033894B (en) 4-anilinoquinayolines
GB2038167B (en) Windscrren wopers
GB2028318B (en) Spiro-oxazolidindiones
GB2025958B (en) Meta-phenylene-diamines
JPS54160373A (en) Arylhydantoin
GB2025734B (en) Electro-acoustictransducer
GB2020654A (en) Azolopyrimidinones
HK44082A (en) X-ray-film-cassette
GB2013938B (en) Servocontrollers
GB2015365B (en) Hydro-extractors
JPS54154730A (en) Novel dialkoxybenzamides
GB2035311B (en) Dibenzothiepins
GB2024403B (en) Flame-holder
GB2034070B (en) Episcope
GB2029189B (en) Haymaker
PH17031A (en) Novel phenoxyalkyloxazolines
GB2029263B (en) Rollermills
JPS54149917A (en) Atmizer
GB2039475B (en) Tetrahydrox-anthones
GB2022469B (en) Fibre-feeder
GB2015512B (en) Arylacetamidocephalosporins
CS686179A2 (en) Zpusob vyroby fenylchinolizidinu
JPS54111917A (en) Rpinter
GB2021431B (en) Fuelinstallation