ZA708590B - Isoquinoline derivatives - Google Patents
Isoquinoline derivativesInfo
- Publication number
- ZA708590B ZA708590B ZA708590A ZA708590A ZA708590B ZA 708590 B ZA708590 B ZA 708590B ZA 708590 A ZA708590 A ZA 708590A ZA 708590 A ZA708590 A ZA 708590A ZA 708590 B ZA708590 B ZA 708590B
- Authority
- ZA
- South Africa
- Prior art keywords
- isoquinoline derivatives
- isoquinoline
- derivatives
- Prior art date
Links
- 125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH10370A CH527194A (de) | 1970-01-06 | 1970-01-06 | Verfahren zur Herstellung von Isochinolin-Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA708590B true ZA708590B (en) | 1971-09-29 |
Family
ID=4179328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA708590A ZA708590B (en) | 1970-01-06 | 1970-12-21 | Isoquinoline derivatives |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS5515476B1 (enExample) |
| AT (1) | AT303041B (enExample) |
| BE (1) | BE761219A (enExample) |
| CA (1) | CA999866A (enExample) |
| CH (2) | CH527194A (enExample) |
| DE (1) | DE2062001C2 (enExample) |
| DK (1) | DK125021B (enExample) |
| ES (1) | ES387016A1 (enExample) |
| FI (1) | FI49503C (enExample) |
| FR (1) | FR2081412B1 (enExample) |
| GB (1) | GB1335261A (enExample) |
| IE (1) | IE34859B1 (enExample) |
| IL (1) | IL35916A (enExample) |
| NL (1) | NL171444C (enExample) |
| NO (1) | NO135315C (enExample) |
| PH (1) | PH9682A (enExample) |
| SE (3) | SE368401B (enExample) |
| YU (1) | YU33660B (enExample) |
| ZA (1) | ZA708590B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA844402B (en) * | 1983-06-23 | 1986-01-29 | Mcneil Pharmaceutical | Hexahydropyrrolo(2,1-a)isoquinoline derivatives |
| US4719216A (en) * | 1983-06-23 | 1988-01-12 | Mcneilab, Inc. | Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants |
| US4595688A (en) * | 1983-06-23 | 1986-06-17 | Mcneilab, Inc. | Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof |
| GB2271566A (en) * | 1992-10-14 | 1994-04-20 | Merck & Co Inc | HIV integrase inhibitors |
| US7163949B1 (en) * | 1999-11-03 | 2007-01-16 | Amr Technology, Inc. | 4-phenyl substituted tetrahydroisoquinolines and use thereof |
| KR100885986B1 (ko) | 1999-11-03 | 2009-03-03 | 에이엠알 테크놀로지, 인크. | 노르에피네프린, 도파민 및 세로토닌의 재흡수를 방지하기위한 아릴 및 헤테로아릴 치환된테트라하이드로이소퀴놀린 및 이들의 용도 |
| KR20080065707A (ko) * | 1999-11-03 | 2008-07-14 | 에이엠알 테크놀로지, 인크. | 4-페닐-치환 테트라히드로이소퀴놀린, 및 노르에피네프린과도파민과 세로토닌의 재흡수를 차단하기 위한 이의 용도 |
| EP1113007A1 (en) | 1999-12-24 | 2001-07-04 | Pfizer Inc. | Tetrahydroisoquinoline compounds as estrogen agonists/antagonists |
| CA2415532C (en) | 2000-07-11 | 2010-05-11 | Albany Molecular Research, Inc. | Novel 4-phenyl substituted tetrahydroisoquinolines therapeutic use thereof |
| KR101389246B1 (ko) | 2004-07-15 | 2014-04-24 | 브리스톨-마이어스스퀴브컴파니 | 아릴- 및 헤테로아릴-치환된 테트라히드로이소퀴놀린, 및 이것의 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도 |
| WO2006138714A2 (en) * | 2005-06-17 | 2006-12-28 | Janssen Pharmaceutica N.V. | Naphthyridine compounds |
| ZA200800440B (en) | 2005-07-15 | 2009-12-30 | Amr Technology Inc | Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
| AR071997A1 (es) | 2008-06-04 | 2010-07-28 | Bristol Myers Squibb Co | Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina |
| US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
| CN102638982B (zh) | 2009-05-12 | 2015-07-08 | 百时美施贵宝公司 | (S)-7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉的晶型及其用途 |
| KR101830447B1 (ko) | 2009-05-12 | 2018-02-20 | 알바니 몰레큘라 리써치, 인크. | 7-(［1,2,4］트리아졸로［1,5-α］피리딘-6-일)-4-(3,4-디클로로페닐)-1,2,3,4-테트라하이드로이소퀴놀린 및 이의 용도 |
| EP2429295B1 (en) | 2009-05-12 | 2013-12-25 | Albany Molecular Research, Inc. | Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1670694B2 (de) * | 1966-05-05 | 1976-07-22 | Hoechst Ag, 6000 Frankfurt | Verfahren zur herstellung von tetrahydroisochinolinen |
-
1970
- 1970-01-06 CH CH10370A patent/CH527194A/de not_active IP Right Cessation
- 1970-01-06 CH CH1011872A patent/CH538477A/de not_active IP Right Cessation
- 1970-12-16 SE SE17063/70A patent/SE368401B/xx unknown
- 1970-12-16 DE DE2062001A patent/DE2062001C2/de not_active Expired
- 1970-12-16 SE SE7313623A patent/SE386672B/xx unknown
- 1970-12-21 ZA ZA708590A patent/ZA708590B/xx unknown
- 1970-12-28 IL IL35916A patent/IL35916A/xx unknown
- 1970-12-29 NL NLAANVRAGE7018956,A patent/NL171444C/xx not_active IP Right Cessation
- 1970-12-31 FI FI703519A patent/FI49503C/fi active
-
1971
- 1971-01-04 IE IE6/71A patent/IE34859B1/xx unknown
- 1971-01-05 BE BE761219A patent/BE761219A/xx not_active IP Right Cessation
- 1971-01-05 NO NO7121A patent/NO135315C/no unknown
- 1971-01-05 AT AT4571A patent/AT303041B/de not_active IP Right Cessation
- 1971-01-05 ES ES387016A patent/ES387016A1/es not_active Expired
- 1971-01-05 DK DK2571AA patent/DK125021B/da not_active IP Right Cessation
- 1971-01-05 FR FR7100097A patent/FR2081412B1/fr not_active Expired
- 1971-01-05 GB GB45471A patent/GB1335261A/en not_active Expired
- 1971-01-06 CA CA102,060A patent/CA999866A/en not_active Expired
- 1971-01-06 JP JP7194A patent/JPS5515476B1/ja active Pending
- 1971-01-06 YU YU19/71A patent/YU33660B/xx unknown
- 1971-01-07 PH PH12087*UA patent/PH9682A/en unknown
-
1973
- 1973-10-05 SE SE7313622A patent/SE399879B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE386672B (sv) | 1976-08-16 |
| IL35916A (en) | 1973-11-28 |
| GB1335261A (en) | 1973-10-24 |
| YU33660B (en) | 1977-12-31 |
| NO135315B (enExample) | 1976-12-13 |
| CH527194A (de) | 1972-08-31 |
| NL7018956A (enExample) | 1971-07-08 |
| CA999866A (en) | 1976-11-16 |
| FI49503B (enExample) | 1975-04-01 |
| FR2081412A1 (enExample) | 1971-12-03 |
| CH538477A (de) | 1973-06-30 |
| DK125021B (da) | 1972-12-18 |
| SE399879B (sv) | 1978-03-06 |
| NO135315C (enExample) | 1977-03-23 |
| ES387016A1 (es) | 1976-05-01 |
| FI49503C (fi) | 1975-07-10 |
| DE2062001A1 (de) | 1971-07-15 |
| JPS5515476B1 (enExample) | 1980-04-23 |
| YU1971A (en) | 1977-06-30 |
| NL171444B (nl) | 1982-11-01 |
| AT303041B (de) | 1972-11-10 |
| IE34859B1 (en) | 1975-09-03 |
| SE368401B (enExample) | 1974-07-01 |
| PH9682A (en) | 1976-02-10 |
| IE34859L (en) | 1971-07-06 |
| DE2062001C2 (de) | 1986-10-16 |
| BE761219A (fr) | 1971-07-05 |
| NL171444C (nl) | 1983-04-05 |
| IL35916A0 (en) | 1971-02-25 |
| FR2081412B1 (enExample) | 1974-04-12 |
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