ZA708590B - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number
ZA708590B
ZA708590B ZA708590A ZA708590A ZA708590B ZA 708590 B ZA708590 B ZA 708590B ZA 708590 A ZA708590 A ZA 708590A ZA 708590 A ZA708590 A ZA 708590A ZA 708590 B ZA708590 B ZA 708590B
Authority
ZA
South Africa
Prior art keywords
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Application number
ZA708590A
Other languages
English (en)
Inventor
A Rheiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA708590B publication Critical patent/ZA708590B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA708590A 1970-01-06 1970-12-21 Isoquinoline derivatives ZA708590B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
ZA708590B true ZA708590B (en) 1971-09-29

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA708590A ZA708590B (en) 1970-01-06 1970-12-21 Isoquinoline derivatives

Country Status (19)

Country Link
JP (1) JPS5515476B1 (enrdf_load_stackoverflow)
AT (1) AT303041B (enrdf_load_stackoverflow)
BE (1) BE761219A (enrdf_load_stackoverflow)
CA (1) CA999866A (enrdf_load_stackoverflow)
CH (2) CH527194A (enrdf_load_stackoverflow)
DE (1) DE2062001C2 (enrdf_load_stackoverflow)
DK (1) DK125021B (enrdf_load_stackoverflow)
ES (1) ES387016A1 (enrdf_load_stackoverflow)
FI (1) FI49503C (enrdf_load_stackoverflow)
FR (1) FR2081412B1 (enrdf_load_stackoverflow)
GB (1) GB1335261A (enrdf_load_stackoverflow)
IE (1) IE34859B1 (enrdf_load_stackoverflow)
IL (1) IL35916A (enrdf_load_stackoverflow)
NL (1) NL171444C (enrdf_load_stackoverflow)
NO (1) NO135315C (enrdf_load_stackoverflow)
PH (1) PH9682A (enrdf_load_stackoverflow)
SE (3) SE368401B (enrdf_load_stackoverflow)
YU (1) YU33660B (enrdf_load_stackoverflow)
ZA (1) ZA708590B (enrdf_load_stackoverflow)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
WO2001032624A1 (en) * 1999-11-03 2001-05-10 Du Pont Pharmaceuticals Company 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
PT1246806E (pt) 1999-11-03 2008-04-03 Amr Technology Inc Tetra-hidroisoquinolinas aril- e heteroaril-substituídas e sua utilização no bloqueio da recaptação de norepinefrina, dopamina e serotonina.
EP1113007A1 (en) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
EP1299393A2 (en) 2000-07-11 2003-04-09 Bristol-Myers Squibb Pharma Company 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
GEP20094640B (en) 2004-07-15 2009-03-10 Bristol Myers Squibb Co Aryl-and heteroaryl-substituted tetrahydro isoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
ATE409188T1 (de) * 2005-06-17 2008-10-15 Janssen Pharmaceutica Nv Naphthyridinverbindungen
MX2008000717A (es) 2005-07-15 2008-03-18 Amr Technology Inc Tetrahidrobenzazepinas substituidas con arilo y heteroarilo y uso de las mismas para bloquear la reabsorcion de norepinefrina, dopamina, y serotonina.
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
ES2446971T3 (es) 2009-05-12 2014-03-11 Albany Molecular Research, Inc. Tetrahidroisoquinolinas sustituidas con arilo, heteroarilo, y heterociclo y su uso
MX2011011900A (es) 2009-05-12 2012-01-20 Squibb Bristol Myers Co Formas cristalinas de (s)-7-([1,2,4]triazolo[1,5-a]piridin-6-il)-4 -(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina y usos de las misma.
AU2010247763B2 (en) 2009-05-12 2015-12-24 Albany Molecular Research, Inc. 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
IE34859B1 (en) 1975-09-03
DE2062001C2 (de) 1986-10-16
CH538477A (de) 1973-06-30
NL171444C (nl) 1983-04-05
NL171444B (nl) 1982-11-01
FR2081412B1 (enrdf_load_stackoverflow) 1974-04-12
IE34859L (en) 1971-07-06
NL7018956A (enrdf_load_stackoverflow) 1971-07-08
BE761219A (fr) 1971-07-05
CA999866A (en) 1976-11-16
SE399879B (sv) 1978-03-06
DK125021B (da) 1972-12-18
NO135315B (enrdf_load_stackoverflow) 1976-12-13
SE368401B (enrdf_load_stackoverflow) 1974-07-01
YU1971A (en) 1977-06-30
IL35916A0 (en) 1971-02-25
YU33660B (en) 1977-12-31
IL35916A (en) 1973-11-28
ES387016A1 (es) 1976-05-01
NO135315C (enrdf_load_stackoverflow) 1977-03-23
DE2062001A1 (de) 1971-07-15
CH527194A (de) 1972-08-31
GB1335261A (en) 1973-10-24
FI49503B (enrdf_load_stackoverflow) 1975-04-01
FR2081412A1 (enrdf_load_stackoverflow) 1971-12-03
PH9682A (en) 1976-02-10
SE386672B (sv) 1976-08-16
AT303041B (de) 1972-11-10
FI49503C (fi) 1975-07-10
JPS5515476B1 (enrdf_load_stackoverflow) 1980-04-23

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