ZA202002923B - Cd47 antibodies and uses thereof for treating cancer - Google Patents
Cd47 antibodies and uses thereof for treating cancerInfo
- Publication number
- ZA202002923B ZA202002923B ZA2020/02923A ZA202002923A ZA202002923B ZA 202002923 B ZA202002923 B ZA 202002923B ZA 2020/02923 A ZA2020/02923 A ZA 2020/02923A ZA 202002923 A ZA202002923 A ZA 202002923A ZA 202002923 B ZA202002923 B ZA 202002923B
- Authority
- ZA
- South Africa
- Prior art keywords
- antibodies
- treating cancer
- cancer
- treating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762593712P | 2017-12-01 | 2017-12-01 | |
| PCT/US2018/062961 WO2019108733A2 (en) | 2017-12-01 | 2018-11-29 | Cd47 antibodies and uses thereof for treating cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA202002923B true ZA202002923B (en) | 2022-12-21 |
Family
ID=64665131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2020/02923A ZA202002923B (en) | 2017-12-01 | 2020-05-19 | Cd47 antibodies and uses thereof for treating cancer |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11180552B2 (https=) |
| EP (1) | EP3717515A2 (https=) |
| JP (2) | JP7391845B2 (https=) |
| KR (1) | KR20200091901A (https=) |
| CN (1) | CN111448213A (https=) |
| AR (1) | AR113862A1 (https=) |
| AU (1) | AU2018375375A1 (https=) |
| BR (1) | BR112020009805A2 (https=) |
| CA (1) | CA3083946A1 (https=) |
| EA (1) | EA202091339A1 (https=) |
| IL (1) | IL274519A (https=) |
| MA (1) | MA51208A (https=) |
| MX (1) | MX2020005463A (https=) |
| SG (1) | SG11202004864TA (https=) |
| TW (1) | TWI831759B (https=) |
| WO (1) | WO2019108733A2 (https=) |
| ZA (1) | ZA202002923B (https=) |
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2018
- 2018-11-29 SG SG11202004864TA patent/SG11202004864TA/en unknown
- 2018-11-29 CN CN201880077186.7A patent/CN111448213A/zh active Pending
- 2018-11-29 AR ARP180103511A patent/AR113862A1/es not_active Application Discontinuation
- 2018-11-29 EA EA202091339A patent/EA202091339A1/ru unknown
- 2018-11-29 AU AU2018375375A patent/AU2018375375A1/en not_active Abandoned
- 2018-11-29 CA CA3083946A patent/CA3083946A1/en active Pending
- 2018-11-29 WO PCT/US2018/062961 patent/WO2019108733A2/en not_active Ceased
- 2018-11-29 TW TW107142777A patent/TWI831759B/zh not_active IP Right Cessation
- 2018-11-29 JP JP2020529364A patent/JP7391845B2/ja active Active
- 2018-11-29 KR KR1020207018697A patent/KR20200091901A/ko not_active Withdrawn
- 2018-11-29 MX MX2020005463A patent/MX2020005463A/es unknown
- 2018-11-29 MA MA051208A patent/MA51208A/fr unknown
- 2018-11-29 US US16/203,809 patent/US11180552B2/en active Active
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- 2018-11-29 BR BR112020009805-1A patent/BR112020009805A2/pt not_active IP Right Cessation
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2020
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| US11180552B2 (en) | 2021-11-23 |
| CA3083946A1 (en) | 2019-06-06 |
| TW201925227A (zh) | 2019-07-01 |
| SG11202004864TA (en) | 2020-06-29 |
| JP2021503927A (ja) | 2021-02-15 |
| US20220135674A1 (en) | 2022-05-05 |
| AU2018375375A1 (en) | 2020-05-28 |
| MA51208A (fr) | 2020-10-07 |
| JP2024026144A (ja) | 2024-02-28 |
| EP3717515A2 (en) | 2020-10-07 |
| TWI831759B (zh) | 2024-02-11 |
| US20190185561A1 (en) | 2019-06-20 |
| BR112020009805A2 (pt) | 2020-10-13 |
| AR113862A1 (es) | 2020-06-17 |
| KR20200091901A (ko) | 2020-07-31 |
| WO2019108733A2 (en) | 2019-06-06 |
| US12071480B2 (en) | 2024-08-27 |
| EA202091339A1 (ru) | 2020-10-21 |
| JP7391845B2 (ja) | 2023-12-05 |
| CN111448213A (zh) | 2020-07-24 |
| IL274519A (en) | 2020-06-30 |
| WO2019108733A3 (en) | 2019-08-15 |
| MX2020005463A (es) | 2020-09-07 |
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