SG11202004864TA - Cd47 antibodies and uses thereof for treating cancer - Google Patents

Cd47 antibodies and uses thereof for treating cancer

Info

Publication number
SG11202004864TA
SG11202004864TA SG11202004864TA SG11202004864TA SG11202004864TA SG 11202004864T A SG11202004864T A SG 11202004864TA SG 11202004864T A SG11202004864T A SG 11202004864TA SG 11202004864T A SG11202004864T A SG 11202004864TA SG 11202004864T A SG11202004864T A SG 11202004864TA
Authority
SG
Singapore
Prior art keywords
antibodies
treating cancer
cancer
treating
Prior art date
Application number
SG11202004864TA
Inventor
Shyra Gardai
Matthew Levengood
Vivian Trang
Lori Westendorf
Christopher Carosino
Michael Feldhaus
Che-Leung Law
Original Assignee
Seattle Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seattle Genetics Inc filed Critical Seattle Genetics Inc
Publication of SG11202004864TA publication Critical patent/SG11202004864TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
SG11202004864TA 2017-12-01 2018-11-29 Cd47 antibodies and uses thereof for treating cancer SG11202004864TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762593712P 2017-12-01 2017-12-01
PCT/US2018/062961 WO2019108733A2 (en) 2017-12-01 2018-11-29 Cd47 antibodies and uses thereof for treating cancer

Publications (1)

Publication Number Publication Date
SG11202004864TA true SG11202004864TA (en) 2020-06-29

Family

ID=64665131

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202004864TA SG11202004864TA (en) 2017-12-01 2018-11-29 Cd47 antibodies and uses thereof for treating cancer

Country Status (16)

Country Link
US (2) US11180552B2 (en)
EP (1) EP3717515A2 (en)
JP (2) JP7391845B2 (en)
KR (1) KR20200091901A (en)
CN (1) CN111448213A (en)
AR (1) AR113862A1 (en)
AU (1) AU2018375375A1 (en)
BR (1) BR112020009805A2 (en)
CA (1) CA3083946A1 (en)
EA (1) EA202091339A1 (en)
IL (1) IL274519A (en)
MA (1) MA51208A (en)
MX (1) MX2020005463A (en)
SG (1) SG11202004864TA (en)
WO (1) WO2019108733A2 (en)
ZA (1) ZA202002923B (en)

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