ZA201607415B - Antibody-drug-conjugate and its use for the treatment of cancer - Google Patents

Antibody-drug-conjugate and its use for the treatment of cancer

Info

Publication number
ZA201607415B
ZA201607415B ZA2016/07415A ZA201607415A ZA201607415B ZA 201607415 B ZA201607415 B ZA 201607415B ZA 2016/07415 A ZA2016/07415 A ZA 2016/07415A ZA 201607415 A ZA201607415 A ZA 201607415A ZA 201607415 B ZA201607415 B ZA 201607415B
Authority
ZA
South Africa
Prior art keywords
conjugate
antibody
cancer
drug
treatment
Prior art date
Application number
ZA2016/07415A
Other languages
English (en)
Inventor
Ian Rilatt
Michel Perez
Liliane Goetsch
Matthieu Broussas
Charlotte Beau-Larvor
Jean-François Haeuw
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of ZA201607415B publication Critical patent/ZA201607415B/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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