CA2946796C - Antibody-drug-conjugate and its use for the treatment of cancer - Google Patents

Antibody-drug-conjugate and its use for the treatment of cancer Download PDF

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Publication number
CA2946796C
CA2946796C CA2946796A CA2946796A CA2946796C CA 2946796 C CA2946796 C CA 2946796C CA 2946796 A CA2946796 A CA 2946796A CA 2946796 A CA2946796 A CA 2946796A CA 2946796 C CA2946796 C CA 2946796C
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Prior art keywords
antibody
drug
igf
binding
target
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CA2946796A
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English (en)
French (fr)
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CA2946796A1 (en
Inventor
Ian RILATT
Michel Perez
Liliane Goetsch
Matthieu BROUSSAS
Charlotte Beau-Larvor
Jean-Francois Haeuw
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Pierre Fabre Medicament SA
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Pierre Fabre Medicament SA
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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