ZA200806266B - Immunomodulatory compounds and treatment of diseases related to an overproduction of inflammatory cytokines - Google Patents
Immunomodulatory compounds and treatment of diseases related to an overproduction of inflammatory cytokinesInfo
- Publication number
- ZA200806266B ZA200806266B ZA200806266A ZA200806266A ZA200806266B ZA 200806266 B ZA200806266 B ZA 200806266B ZA 200806266 A ZA200806266 A ZA 200806266A ZA 200806266 A ZA200806266 A ZA 200806266A ZA 200806266 B ZA200806266 B ZA 200806266B
- Authority
- ZA
- South Africa
- Prior art keywords
- overproduction
- treatment
- inflammatory cytokines
- diseases related
- immunomodulatory compounds
- Prior art date
Links
- 102000004127 Cytokines Human genes 0.000 title 1
- 108090000695 Cytokines Proteins 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000002519 immonomodulatory effect Effects 0.000 title 1
- 230000002757 inflammatory effect Effects 0.000 title 1
- 238000012261 overproduction Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
- A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IBPCT/IB2006/050748 | 2006-03-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200806266B true ZA200806266B (en) | 2010-05-26 |
Family
ID=38475231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200806266A ZA200806266B (en) | 2006-03-09 | 2007-03-09 | Immunomodulatory compounds and treatment of diseases related to an overproduction of inflammatory cytokines |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US7915240B2 (https=) |
| EP (1) | EP2051728A4 (https=) |
| JP (1) | JP5341526B2 (https=) |
| KR (1) | KR20080105048A (https=) |
| CN (1) | CN101511379A (https=) |
| AU (1) | AU2007222135B2 (https=) |
| BR (1) | BRPI0708363A2 (https=) |
| CA (1) | CA2645053A1 (https=) |
| IL (1) | IL192837A (https=) |
| MX (1) | MX2008011360A (https=) |
| NO (1) | NO20084195L (https=) |
| RU (1) | RU2498813C2 (https=) |
| WO (1) | WO2007102081A2 (https=) |
| ZA (1) | ZA200806266B (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007102081A2 (en) | 2006-03-09 | 2007-09-13 | Om Pharma | Immunomodulatory compounds and treatment of diseases related to an overproduction of inflammatory cytokines |
| KR101108161B1 (ko) | 2009-12-24 | 2012-01-31 | 삼성모바일디스플레이주식회사 | 유기 발광 표시 장치 및 그 제조방법 |
| US10065978B2 (en) * | 2015-11-24 | 2018-09-04 | University Of South Carolina | Cysteine-modifying substrate analogue inhibitors of ribose 5-phosphate isomerase for parasitic diseases, along with methods of their formation and use |
| US10682359B2 (en) | 2017-03-31 | 2020-06-16 | University Of South Carolina | Inhibitors of glucose kinases, along with methods of their formation and use |
| US11059842B2 (en) | 2019-04-29 | 2021-07-13 | University Of South Carolina | Monosaccharide amine and 3-nitro-2-phenyl-2H-chromene based inhibitors of glucose kinases |
| US11555047B2 (en) | 2019-10-31 | 2023-01-17 | University Of South Carolina | One-step synthesis of phosphate-based inhibitors and applications thereof |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL187439B1 (pl) * | 1996-01-23 | 2004-07-30 | Icn Pharmaceuticals | Zastosowanie rybawiryny |
| JP4305662B2 (ja) * | 1996-09-30 | 2009-07-29 | 大塚製薬株式会社 | サイトカイン産生抑制剤及び接着抑制剤 |
| ATE238328T1 (de) * | 1996-10-16 | 2003-05-15 | Ribapharm Inc | Monozyklische l-nukleoside, analoga und ihre anwendungen |
| KR20010021789A (ko) | 1997-08-04 | 2001-03-15 | 야스이 쇼사꾸 | 촉매 및 방향족 카보네이트의 제조방법 |
| IT1296985B1 (it) * | 1997-12-19 | 1999-08-03 | Zambon Spa | Derivati benzazinici inibitori della fosfodiesterasi 4 |
| WO1999061412A1 (en) * | 1998-05-22 | 1999-12-02 | Welfide Corporation | Hydroxamic acid derivatives and medicinal utilization thereof |
| CN1168702C (zh) * | 1998-06-30 | 2004-09-29 | Om药业 | 酰基-二肽类化合物,其制备方法以及含有前述化合物的药物组合物 |
| US6831069B2 (en) | 1999-08-27 | 2004-12-14 | Ribapharm Inc. | Pyrrolo[2,3-d]pyrimidine nucleoside analogs |
| WO2001046127A1 (fr) * | 1999-12-22 | 2001-06-28 | Om Pharma | Pseudodipeptides acyles porteurs d'un bras auxiliaire fonctionnalise |
| EP1261736A4 (en) * | 2000-01-25 | 2004-12-29 | Nuvelo Inc | PROCESS, POLYPEPTIDES AND POLYNUCLEOTIDES, ASSOCIATED WITH "PREADIPOCYTE FACTOR-1" (PREF-1) |
| JP2001316260A (ja) * | 2000-02-29 | 2001-11-13 | Meiji Milk Prod Co Ltd | カバラクトン類を有効成分とするＴＮＦ−α産生抑制剤 |
| DE20220947U1 (de) * | 2001-02-28 | 2004-09-30 | Ribapharm, Inc., Costa Mesa | Pyrrolo2,3-dpyrimidin-Nucleosidanaloga |
| RU2190422C1 (ru) * | 2001-04-25 | 2002-10-10 | Кожемякин Леонид Андреевич | Аэрозоль для ингаляций фармацевтической композиции глутовент и способ лечения с его использованием |
| JP4902913B2 (ja) * | 2001-07-11 | 2012-03-21 | 森下仁丹株式会社 | ＴＮＦ−α産生抑制剤 |
| JP2004107220A (ja) * | 2002-09-13 | 2004-04-08 | Mitsubishi Pharma Corp | ＴＮＦ−α産生抑制剤 |
| JP2004256403A (ja) * | 2003-02-25 | 2004-09-16 | Kyowa Hakko Kogyo Co Ltd | ＴＮＦ−α産生抑制剤 |
| BRPI0407519A (pt) * | 2003-03-07 | 2006-02-14 | Kowa Co | derivados de benzofurano |
| WO2007102081A2 (en) | 2006-03-09 | 2007-09-13 | Om Pharma | Immunomodulatory compounds and treatment of diseases related to an overproduction of inflammatory cytokines |
-
2007
- 2007-03-09 WO PCT/IB2007/000567 patent/WO2007102081A2/en not_active Ceased
- 2007-03-09 CA CA002645053A patent/CA2645053A1/en not_active Abandoned
- 2007-03-09 CN CNA2007800075716A patent/CN101511379A/zh active Pending
- 2007-03-09 KR KR1020087020919A patent/KR20080105048A/ko not_active Ceased
- 2007-03-09 BR BRPI0708363-7A patent/BRPI0708363A2/pt not_active IP Right Cessation
- 2007-03-09 RU RU2008139985/15A patent/RU2498813C2/ru not_active IP Right Cessation
- 2007-03-09 JP JP2008557846A patent/JP5341526B2/ja not_active Expired - Fee Related
- 2007-03-09 MX MX2008011360A patent/MX2008011360A/es active IP Right Grant
- 2007-03-09 AU AU2007222135A patent/AU2007222135B2/en not_active Ceased
- 2007-03-09 EP EP07733936A patent/EP2051728A4/en not_active Withdrawn
- 2007-03-09 US US12/279,845 patent/US7915240B2/en not_active Expired - Fee Related
- 2007-03-09 ZA ZA200806266A patent/ZA200806266B/xx unknown
-
2008
- 2008-07-16 IL IL192837A patent/IL192837A/en not_active IP Right Cessation
- 2008-10-07 NO NO20084195A patent/NO20084195L/no not_active Application Discontinuation
-
2011
- 2011-03-28 US US13/073,737 patent/US8618080B2/en not_active Expired - Fee Related
-
2013
- 2013-11-27 US US14/092,589 patent/US20140086960A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NO20084195L (no) | 2008-10-07 |
| WO2007102081A3 (en) | 2009-04-23 |
| US20090054378A1 (en) | 2009-02-26 |
| WO2007102081A2 (en) | 2007-09-13 |
| JP2009529523A (ja) | 2009-08-20 |
| KR20080105048A (ko) | 2008-12-03 |
| RU2008139985A (ru) | 2010-04-20 |
| AU2007222135A1 (en) | 2007-09-13 |
| US8618080B2 (en) | 2013-12-31 |
| EP2051728A4 (en) | 2010-03-31 |
| MX2008011360A (es) | 2009-03-03 |
| US20120178721A1 (en) | 2012-07-12 |
| CA2645053A1 (en) | 2007-09-13 |
| EP2051728A2 (en) | 2009-04-29 |
| JP5341526B2 (ja) | 2013-11-13 |
| CN101511379A (zh) | 2009-08-19 |
| AU2007222135B2 (en) | 2012-02-02 |
| RU2498813C2 (ru) | 2013-11-20 |
| IL192837A (en) | 2013-12-31 |
| US20140086960A1 (en) | 2014-03-27 |
| US7915240B2 (en) | 2011-03-29 |
| BRPI0708363A2 (pt) | 2011-05-24 |
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