ZA200805918B - Nanoclusters for delivery of therapeutics - Google Patents

Nanoclusters for delivery of therapeutics

Info

Publication number
ZA200805918B
ZA200805918B ZA200805918A ZA200805918A ZA200805918B ZA 200805918 B ZA200805918 B ZA 200805918B ZA 200805918 A ZA200805918 A ZA 200805918A ZA 200805918 A ZA200805918 A ZA 200805918A ZA 200805918 B ZA200805918 B ZA 200805918B
Authority
ZA
South Africa
Prior art keywords
nanoclusters
therapeutics
delivery
Prior art date
Application number
ZA200805918A
Other languages
English (en)
Inventor
Cory J Berkland
Shi Lianjun
Original Assignee
Univ Kansas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kansas filed Critical Univ Kansas
Publication of ZA200805918B publication Critical patent/ZA200805918B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/5115Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1688Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991Coated
    • Y10T428/2998Coated including synthetic resin or polymer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nanotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Dermatology (AREA)
  • Composite Materials (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ZA200805918A 2005-12-16 2008-07-07 Nanoclusters for delivery of therapeutics ZA200805918B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75117205P 2005-12-16 2005-12-16

Publications (1)

Publication Number Publication Date
ZA200805918B true ZA200805918B (en) 2009-05-27

Family

ID=37808148

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200805918A ZA200805918B (en) 2005-12-16 2008-07-07 Nanoclusters for delivery of therapeutics

Country Status (11)

Country Link
US (3) US7651770B2 (https=)
EP (1) EP1968550A2 (https=)
JP (1) JP2009519975A (https=)
CN (1) CN101370479A (https=)
AU (1) AU2006330627A1 (https=)
BR (1) BRPI0619938A2 (https=)
CA (1) CA2633380A1 (https=)
IL (1) IL192159A0 (https=)
MX (1) MX2008007697A (https=)
WO (1) WO2007076295A2 (https=)
ZA (1) ZA200805918B (https=)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040096515A1 (en) * 2001-12-07 2004-05-20 Bausch Andreas R. Methods and compositions for encapsulating active agents
EP2248578B1 (en) 2005-03-04 2012-06-06 President and Fellows of Harvard College Method for forming multiple emulsions
WO2010009146A1 (en) * 2008-07-15 2010-01-21 University Of Kansas Nanoclusters for delivery of poorly water soluble drug nanoparticles
US8906392B2 (en) * 2005-12-16 2014-12-09 University Of Kansas Nanocluster compositions and methods
US7993749B2 (en) * 2005-12-16 2011-08-09 University Of Kansas Nanoparticles comprising a nanoparticle template and a polymer shell having an amide side chain, and method of making thereof
US8445018B2 (en) 2006-09-15 2013-05-21 Cima Labs Inc. Abuse resistant drug formulation
ES2425969T3 (es) * 2007-04-27 2013-10-18 Kyushu University, National University Corporation Agente para el tratamiento de enfermedades pulmonares
EP2170283B1 (en) 2007-06-22 2019-01-09 Board of Regents, The University of Texas System Formation of stable submicron peptide or protein particles by thin film freezing
US20090047318A1 (en) * 2007-08-16 2009-02-19 Abbott Cardiovascular Systems Inc. Nanoparticle-coated medical devices and formulations for treating vascular disease
US20090123509A1 (en) * 2007-11-08 2009-05-14 Cory Berkland Biodegradable Colloidal Gels as Moldable Tissue Engineering Scaffolds
US20090169639A1 (en) * 2007-12-28 2009-07-02 Boston Scientific Scimed, Inc. Particles for injection and processes for forming the same
US9182391B2 (en) * 2008-05-09 2015-11-10 Arkray, Inc. Method of producing insoluble carrier particles, insoluble carrier particles, measurement reagent, specimen analyzing tool, and immunoturbidimetric assay
JP5841708B2 (ja) * 2008-07-01 2016-01-13 日東電工株式会社 表面被覆微粒子の医薬組成物
EP2376522A4 (en) 2008-11-16 2013-12-25 Univ Texas LOW VISCOSIS HIGHLY CONCENTRATED SUSPENSIONS
US8053744B2 (en) * 2009-04-13 2011-11-08 Src, Inc. Location analysis using nucleic acid-labeled tags
US10952965B2 (en) * 2009-05-15 2021-03-23 Baxter International Inc. Compositions and methods for drug delivery
US20120211084A1 (en) 2009-09-02 2012-08-23 President And Fellows Of Harvard College Multiple emulsions created using jetting and other techniques
US12419839B2 (en) 2009-10-09 2025-09-23 Signablok, Inc. Methods and compositions for targeted delivery of protein fragments
US10525152B2 (en) 2009-10-09 2020-01-07 Signablok, Inc. Methods and compositions for targeted imaging
KR101878749B1 (ko) * 2010-03-05 2018-07-17 삼성전자주식회사 표적 세포의 분리 방법 및 키트
CN102971069A (zh) * 2010-03-17 2013-03-13 哈佛学院院长等 熔体乳化
HUP1000299A2 (hu) 2010-06-08 2012-02-28 Nanoform Cardiovascular Therapeutics Ltd Nanostrukturált Atorvastatint, gyógyszerészetileg elfogadott sóit és kokristályait tartalmazó készítmény és eljárás elõállításukra
US8703493B2 (en) 2010-06-15 2014-04-22 Src, Inc. Location analysis using fire retardant-protected nucleic acid-labeled tags
US20120016217A1 (en) * 2010-07-15 2012-01-19 Indian Institute Of Technology Bombay Biosensor for health monitoring and uses thereof
WO2012018628A1 (en) 2010-07-26 2012-02-09 Board Of Regents, The University Of Texas System Methods for inducing an immune response via buccal and/or sublingual administration of a vaccine
US8716027B2 (en) 2010-08-03 2014-05-06 Src, Inc. Nucleic acid-labeled tags associated with odorant
CN103221070B (zh) * 2010-08-30 2019-07-12 哈佛大学校长及研究员协会 用于狭窄病变和溶解血栓疗法的切变控制释放
JP2014514275A (ja) * 2011-03-10 2014-06-19 ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム タンパク質ナノ粒子分散系
EP2714254B1 (en) 2011-05-23 2017-09-06 President and Fellows of Harvard College Control of emulsions, including multiple emulsions
WO2012162555A2 (en) * 2011-05-24 2012-11-29 The Regents Of The University Of California Heparin nanoclusters
PT2714419E (pt) * 2011-06-02 2015-11-20 Fábrica Nac De Moneda Y Timbre Real Casa De La Moneda Utilização de marcadores de raman para autenticar documentos de segurança
BR112014000141A2 (pt) 2011-07-06 2017-06-13 Harvard College emulsões múltiplas e técnicas para a formação de emulsões múltiplas
RU2666963C2 (ru) 2012-04-13 2018-09-13 Глаксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Агрегированные частицы
JP2015520194A (ja) * 2012-06-07 2015-07-16 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 薬物標的指向化のためのナノ療法
US9757529B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
US9757395B2 (en) 2012-12-20 2017-09-12 Otitopic Inc. Dry powder inhaler and methods of use
US9974850B2 (en) * 2013-01-25 2018-05-22 Board Of Regents, The University Of Texas System Immunogenic compositions and uses thereof
HK1218720A1 (zh) 2013-04-30 2017-03-10 欧缇托匹克公司 干粉制剂及使用方法
IL292567B2 (en) 2013-08-13 2025-06-01 Univ Northwestern Peptide conjugated particles
MX2016006275A (es) * 2013-11-13 2017-01-05 Tillotts Pharma Ag Sistema multiparticulado para administrar drogas.
CN104550936B (zh) * 2014-12-31 2017-05-31 中国科学院合肥物质科学研究院 纳米颗粒组装的胶状体材料及其制备方法
JP6910029B2 (ja) * 2015-08-17 2021-07-28 国立研究開発法人科学技術振興機構 ナノクラスター分散液、ナノクラスター膜、ナノクラスター分散体、ナノクラスター分散液の製造方法およびナノクラスター分散液の製造装置
US20170128424A1 (en) * 2015-11-11 2017-05-11 Qrono, Inc. Sustained release pharmaceutical compositions and methods of use
KR101803283B1 (ko) * 2016-12-30 2017-12-01 (주)아모레퍼시픽 항노화용 또는 주름개선용 화장료 조성물
WO2019010329A1 (en) * 2017-07-06 2019-01-10 The Trustees Of The University Of Pennsylvania AGOREGATES OF INORGANIC NANOPARTICLES COATED WITH AMPHIPHILIC COLOR
US10786456B2 (en) 2017-09-22 2020-09-29 Otitopic Inc. Inhaled aspirin and magnesium to treat inflammation
KR102681843B1 (ko) 2017-09-22 2024-07-05 벡추라 인코포레이티드 스테아르산마그네슘을 갖는 건조 분말 조성물
US11819488B2 (en) 2018-02-23 2023-11-21 Rhnanopharma Nanosuspensions of salsalate and methods of using the same
US12533319B2 (en) 2019-04-02 2026-01-27 Seawagen Research Institute Zhengzhou Dynamic clusters of atom particles activated in extracellular fluid
US20230355540A1 (en) 2020-09-29 2023-11-09 Oxford University Innovation Limited Stroke treatment

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09913A (ja) * 1995-06-14 1997-01-07 Res Dev Corp Of Japan コロイド粒子クラスターとその形成方法
US5814370A (en) * 1996-06-11 1998-09-29 Sandia Corporation Encapsulation of nanoclusters in dried gel materials via an inverse micelle/sol gel synthesis
US7521068B2 (en) * 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
US6656568B1 (en) * 1999-05-28 2003-12-02 The Regents Of The University Of Colorado Ordered arrays of nanoclusters
GB9929919D0 (en) * 1999-12-17 2000-02-09 Hannah Research Inst The Calcium phosphate nanoclusters and their applications
JP2003535063A (ja) 2000-06-01 2003-11-25 ザ・ボード・オブ・リージェンツ・フォー・オクラホマ・ステート・ユニバーシティー 放射線医薬としてのナノ粒子のバイオコンジュゲート
DE60140625D1 (de) 2000-08-15 2010-01-07 Univ Illinois Verfahren zur herstellung von mikropartikeln
US20030138490A1 (en) 2001-09-08 2003-07-24 Zhibing Hu Synthesis and uses of polymer gel nanoparticle networks
US20030062372A1 (en) * 2001-10-02 2003-04-03 Metso Minerals (Trelleborg) Ab Wear-resistant lining element and wear lining made thereof
US7563457B2 (en) 2001-10-02 2009-07-21 The Regents Of The University Of California Nanoparticle assembled hollow spheres
US6562403B2 (en) * 2001-10-15 2003-05-13 Kansas State University Research Foundation Synthesis of substantially monodispersed colloids
CN1643629A (zh) * 2002-01-25 2005-07-20 科纳卡科技有限公司 光电池结构和材料
EP1480691A4 (en) * 2002-03-05 2007-11-28 Univ State Cleveland AGGLOMERATED PARTICLES FOR THE DISPOSAL OF A MEDICINAL PRODUCT IN AEROSOL FORM
WO2003100034A2 (en) 2002-03-18 2003-12-04 Sciperio, Inc. Dentritic cell nodes
JP4142318B2 (ja) * 2002-03-20 2008-09-03 株式会社ホソカワ粉体技術研究所 薬物含有複合粒子の製造方法
KR20050037992A (ko) * 2002-06-05 2005-04-25 유니버시티 오브 플로리다 안약 전달 장치
EP1543841A4 (en) * 2002-08-15 2011-03-16 Yunqing Liu SOLID PHARMACEUTICAL NANO FORMULATION AND MANUFACTURING METHOD THEREFOR
US7811605B2 (en) * 2002-11-06 2010-10-12 Uluru Inc. Method of formation of shape-retentive aggregates of gel particles and their uses
US6928201B2 (en) * 2002-11-15 2005-08-09 Sunrise Telecom Incorporated Method and apparatus for providing controllable second-order polarization mode dispersion
WO2004096140A2 (en) * 2003-04-25 2004-11-11 The Penn State Research Foundation Method and system for systemic delivery of growth arresting, lipid-derived bioactive compounds
CA2531032A1 (en) 2003-07-09 2005-02-17 Vaxdesign Corporation Programmed immune responses using a vaccination node
CA2435632A1 (en) 2003-07-21 2005-01-21 Warren Hugh Finlay Formulation of powder containing nanoparticles for aerosol delivery to the lung
CA2550518C (en) * 2003-12-19 2010-02-09 Scf Technologies A/S Systems for preparing fine particles and other substances
JP2007515471A (ja) * 2003-12-22 2007-06-14 ブラッコ・リサーチ・ソシエテ・アノニム 造影イメージング用の活性成分を有する気体封入マイクロベシクルのアセンブリー
US7610074B2 (en) * 2004-01-08 2009-10-27 The Board Of Trustees Of The University Of Illinois Multi-functional plasmon-resonant contrast agents for optical coherence tomography

Also Published As

Publication number Publication date
BRPI0619938A2 (pt) 2011-10-25
US7651770B2 (en) 2010-01-26
EP1968550A2 (en) 2008-09-17
AU2006330627A1 (en) 2007-07-05
MX2008007697A (es) 2008-09-26
WO2007076295A2 (en) 2007-07-05
CA2633380A1 (en) 2007-07-05
JP2009519975A (ja) 2009-05-21
US20090081295A1 (en) 2009-03-26
US20070172653A1 (en) 2007-07-26
WO2007076295A3 (en) 2007-11-29
IL192159A0 (en) 2008-12-29
CN101370479A (zh) 2009-02-18
US20090053316A1 (en) 2009-02-26

Similar Documents

Publication Publication Date Title
ZA200805918B (en) Nanoclusters for delivery of therapeutics
EP1896996A4 (en) TARGETED DELIVERY OF CONTENT
GB0602562D0 (en) Content Delivery
EP1934731A4 (en) CONTENT DELIVERY COMPATIBLE WITH THE DEVICE
SI2101740T1 (sl) Nov nezlorabljiv farmacevtski sestavek, obsegajoč opiode
IL195247A0 (en) Inhaler
PL2007457T3 (pl) Inhalator
IL198651A0 (en) COMPOSITION COMPRISING (-)-Ôêå9-TRANS-TETRAHYDROCANNABIONOL
GB0821019D0 (en) Nanostructures suitable for delivery of agents
GB2434754B (en) Inhaler
GB0605553D0 (en) Casting composition
IL195817A0 (en) Use of 2-benzoyl-imidazopyridines in therapeutics
GB2435420B (en) Delivery means
AP2006000208S (en) Inhaler
GB0709390D0 (en) Delivery means
EP2059135A4 (en) NOVEL COMPOSITION
HK1124542A (en) Nanoclusters for delivery of therapeutics
AU311491S (en) Inhaler
GB0616952D0 (en) Delivery
GB0609094D0 (en) Steel set chair
GB0509642D0 (en) Therapeutics agents
GB0613428D0 (en) In situ delivery of probotic formulations
TWM299704U (en) Improved structure for postcard
ZA200607041B (en) Intramammary formulations
GB0605454D0 (en) Cue factor