ZA200805918B - Nanoclusters for delivery of therapeutics - Google Patents
Nanoclusters for delivery of therapeuticsInfo
- Publication number
- ZA200805918B ZA200805918B ZA200805918A ZA200805918A ZA200805918B ZA 200805918 B ZA200805918 B ZA 200805918B ZA 200805918 A ZA200805918 A ZA 200805918A ZA 200805918 A ZA200805918 A ZA 200805918A ZA 200805918 B ZA200805918 B ZA 200805918B
- Authority
- ZA
- South Africa
- Prior art keywords
- nanoclusters
- therapeutics
- delivery
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5115—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
- A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5192—Processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y10T428/2998—Coated including synthetic resin or polymer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nanotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Biomedical Technology (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Inorganic Chemistry (AREA)
- Composite Materials (AREA)
- Dermatology (AREA)
- General Physics & Mathematics (AREA)
- Materials Engineering (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75117205P | 2005-12-16 | 2005-12-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200805918B true ZA200805918B (en) | 2009-05-27 |
Family
ID=37808148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200805918A ZA200805918B (en) | 2005-12-16 | 2008-07-07 | Nanoclusters for delivery of therapeutics |
Country Status (11)
Country | Link |
---|---|
US (3) | US7651770B2 (xx) |
EP (1) | EP1968550A2 (xx) |
JP (1) | JP2009519975A (xx) |
CN (1) | CN101370479A (xx) |
AU (1) | AU2006330627A1 (xx) |
BR (1) | BRPI0619938A2 (xx) |
CA (1) | CA2633380A1 (xx) |
IL (1) | IL192159A0 (xx) |
MX (1) | MX2008007697A (xx) |
WO (1) | WO2007076295A2 (xx) |
ZA (1) | ZA200805918B (xx) |
Families Citing this family (48)
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US20040096515A1 (en) * | 2001-12-07 | 2004-05-20 | Bausch Andreas R. | Methods and compositions for encapsulating active agents |
WO2006096571A2 (en) | 2005-03-04 | 2006-09-14 | President And Fellows Of Harvard College | Method and apparatus for forming multiple emulsions |
US8906392B2 (en) * | 2005-12-16 | 2014-12-09 | University Of Kansas | Nanocluster compositions and methods |
US7993749B2 (en) * | 2005-12-16 | 2011-08-09 | University Of Kansas | Nanoparticles comprising a nanoparticle template and a polymer shell having an amide side chain, and method of making thereof |
WO2010009146A1 (en) * | 2008-07-15 | 2010-01-21 | University Of Kansas | Nanoclusters for delivery of poorly water soluble drug nanoparticles |
US8445018B2 (en) | 2006-09-15 | 2013-05-21 | Cima Labs Inc. | Abuse resistant drug formulation |
ES2425969T3 (es) * | 2007-04-27 | 2013-10-18 | Kyushu University, National University Corporation | Agente para el tratamiento de enfermedades pulmonares |
CA2691531C (en) | 2007-06-22 | 2016-11-01 | Board Of Regents,The University Of Texas System | Formation of stable submicron peptide or protein particles by thin film freezing |
US20090047318A1 (en) * | 2007-08-16 | 2009-02-19 | Abbott Cardiovascular Systems Inc. | Nanoparticle-coated medical devices and formulations for treating vascular disease |
US20090123509A1 (en) * | 2007-11-08 | 2009-05-14 | Cory Berkland | Biodegradable Colloidal Gels as Moldable Tissue Engineering Scaffolds |
US20090169639A1 (en) * | 2007-12-28 | 2009-07-02 | Boston Scientific Scimed, Inc. | Particles for injection and processes for forming the same |
JP5351054B2 (ja) * | 2008-05-09 | 2013-11-27 | アークレイ株式会社 | 不溶性担体粒子の製造方法、不溶性担体粒子、測定試薬、検体分析用具および免疫比濁法 |
JP5841708B2 (ja) * | 2008-07-01 | 2016-01-13 | 日東電工株式会社 | 表面被覆微粒子の医薬組成物 |
EP2376522A4 (en) | 2008-11-16 | 2013-12-25 | Univ Texas | LOW VISCOSIS HIGHLY CONCENTRATED SUSPENSIONS |
US8053744B2 (en) * | 2009-04-13 | 2011-11-08 | Src, Inc. | Location analysis using nucleic acid-labeled tags |
US10952965B2 (en) * | 2009-05-15 | 2021-03-23 | Baxter International Inc. | Compositions and methods for drug delivery |
CN102574078B (zh) | 2009-09-02 | 2016-05-18 | 哈佛学院院长等 | 使用喷射和其它技术产生的多重乳液 |
WO2011044545A2 (en) | 2009-10-09 | 2011-04-14 | Sigalov Alexander B | Methods and compositions for targeted imaging |
KR101878749B1 (ko) * | 2010-03-05 | 2018-07-17 | 삼성전자주식회사 | 표적 세포의 분리 방법 및 키트 |
US20110229545A1 (en) * | 2010-03-17 | 2011-09-22 | President And Fellows Of Harvard College | Melt emulsification |
HUP1000299A2 (hu) | 2010-06-08 | 2012-02-28 | Nanoform Cardiovascular Therapeutics Ltd | Nanostrukturált Atorvastatint, gyógyszerészetileg elfogadott sóit és kokristályait tartalmazó készítmény és eljárás elõállításukra |
US8703493B2 (en) | 2010-06-15 | 2014-04-22 | Src, Inc. | Location analysis using fire retardant-protected nucleic acid-labeled tags |
US20120016217A1 (en) * | 2010-07-15 | 2012-01-19 | Indian Institute Of Technology Bombay | Biosensor for health monitoring and uses thereof |
US8716027B2 (en) | 2010-08-03 | 2014-05-06 | Src, Inc. | Nucleic acid-labeled tags associated with odorant |
US20130295012A1 (en) * | 2010-08-30 | 2013-11-07 | President And Fellows Of Harvard College | Shear controlled release for stenotic lesions and thrombolytic therapies |
JP2014514275A (ja) * | 2011-03-10 | 2014-06-19 | ボード・オブ・リージエンツ,ザ・ユニバーシテイ・オブ・テキサス・システム | タンパク質ナノ粒子分散系 |
BR112013029729A2 (pt) | 2011-05-23 | 2017-01-24 | Basf Se | controle de emulsões, incluindo emulsões múltiplas |
WO2012162555A2 (en) * | 2011-05-24 | 2012-11-29 | The Regents Of The University Of California | Heparin nanoclusters |
JP6009549B2 (ja) * | 2011-06-02 | 2016-10-19 | ファブリカ、ナシオナル、デ、モネダ、イ、ティンブレ−レアル、カサ、デ、ラ、モネダFabrica Nacional De Moneda Y Timbre−Real Casa De La Moneda | セキュリティ文書の真正性を認証するためのラマンマーカーの使用 |
US20140220350A1 (en) | 2011-07-06 | 2014-08-07 | President And Fellows Of Harvard College | Multiple emulsions and techniques for the formation of multiple emulsions |
BR112014025518B1 (pt) | 2012-04-13 | 2022-05-24 | Glaxosmithkline Intellectual Property Development Limited | Partículas agregadas de umeclidinium, vilanterol e fluticasona, composição em pó, inalador, processo para a preparação de partículas agregadas, e, uso de estearato de magnésio em partículas agregadas |
US20150147276A1 (en) * | 2012-06-07 | 2015-05-28 | President And Fellows Of Harvard College | Nanotherapeutics for drug targeting |
US9757529B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
US9757395B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
US9974850B2 (en) | 2013-01-25 | 2018-05-22 | Board Of Regents, The University Of Texas System | Immunogenic compositions and uses thereof |
EP2991634A1 (en) | 2013-04-30 | 2016-03-09 | Otitopic Inc. | Dry powder formulations and methods of use |
RS59801B2 (sr) | 2013-08-13 | 2024-03-29 | Univ Northwestern | Čestice konjugovane peptidom |
US20160287521A1 (en) * | 2013-11-13 | 2016-10-06 | Tillotts Pharma Ag | Multi-particulate drug delivery system |
CN104550936B (zh) * | 2014-12-31 | 2017-05-31 | 中国科学院合肥物质科学研究院 | 纳米颗粒组装的胶状体材料及其制备方法 |
EP3351298B1 (en) * | 2015-08-17 | 2022-04-13 | Japan Science and Technology Agency | Method for producing liquid nanocluster dispersion, and device for producing liquid nanocluster dispersion |
WO2017083717A1 (en) * | 2015-11-11 | 2017-05-18 | Qrono, Inc. | Sustained release pharmaceutical compositions and methods of use |
KR101803283B1 (ko) * | 2016-12-30 | 2017-12-01 | (주)아모레퍼시픽 | 항노화용 또는 주름개선용 화장료 조성물 |
US11446391B2 (en) | 2017-07-06 | 2022-09-20 | The Trustees Of The University Of Pennsylvania | Amphiphilic dye-coated inorganic nanoparticle clusters |
KR102507987B1 (ko) | 2017-09-22 | 2023-03-21 | 벡추라 인코포레이티드 | 스테아르산마그네슘을 갖는 건조 분말 조성물 |
US10786456B2 (en) | 2017-09-22 | 2020-09-29 | Otitopic Inc. | Inhaled aspirin and magnesium to treat inflammation |
WO2019165240A1 (en) * | 2018-02-23 | 2019-08-29 | Rhnanopharma | Nanosuspensions of salsalate and methods of using the same |
EP3934626A4 (en) * | 2019-04-02 | 2022-11-02 | Xichuan Seawagen Company Limited | DYNAMIC AGGREGATES OF ACTIVATED ATOM PARTICLES IN AN EXTRACELLULAR FLUID |
AU2021353913A1 (en) | 2020-09-29 | 2023-06-01 | Oxford University Innovation Limited | Stroke treatment |
Family Cites Families (25)
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JPH09913A (ja) * | 1995-06-14 | 1997-01-07 | Res Dev Corp Of Japan | コロイド粒子クラスターとその形成方法 |
US5814370A (en) * | 1996-06-11 | 1998-09-29 | Sandia Corporation | Encapsulation of nanoclusters in dried gel materials via an inverse micelle/sol gel synthesis |
US7521068B2 (en) * | 1998-11-12 | 2009-04-21 | Elan Pharma International Ltd. | Dry powder aerosols of nanoparticulate drugs |
US6656568B1 (en) * | 1999-05-28 | 2003-12-02 | The Regents Of The University Of Colorado | Ordered arrays of nanoclusters |
GB9929919D0 (en) * | 1999-12-17 | 2000-02-09 | Hannah Research Inst The | Calcium phosphate nanoclusters and their applications |
JP2003535063A (ja) * | 2000-06-01 | 2003-11-25 | ザ・ボード・オブ・リージェンツ・フォー・オクラホマ・ステート・ユニバーシティー | 放射線医薬としてのナノ粒子のバイオコンジュゲート |
KR100902625B1 (ko) * | 2000-08-15 | 2009-06-15 | 더 보드 오브 트러스티즈 오브 더 유니버시티 오브 일리노이 | 마이크로입자 |
US20030138490A1 (en) * | 2001-09-08 | 2003-07-24 | Zhibing Hu | Synthesis and uses of polymer gel nanoparticle networks |
US20030062372A1 (en) * | 2001-10-02 | 2003-04-03 | Metso Minerals (Trelleborg) Ab | Wear-resistant lining element and wear lining made thereof |
WO2003062372A2 (en) | 2001-10-02 | 2003-07-31 | The Regents Of The University Of California | Nanoparticle assembled hollow spheres |
US6562403B2 (en) * | 2001-10-15 | 2003-05-13 | Kansas State University Research Foundation | Synthesis of substantially monodispersed colloids |
CA2474494A1 (en) * | 2002-01-25 | 2003-08-07 | Savvas E. Hadjikyriacou | Photovoltaic cell components and materials |
US7138136B2 (en) * | 2002-03-05 | 2006-11-21 | Cleveland State University | Agglomerated particles for aerosol drug delivery |
US20060078540A1 (en) | 2002-03-18 | 2006-04-13 | Warren William L | Dendritic cell nodes |
JP4142318B2 (ja) * | 2002-03-20 | 2008-09-03 | 株式会社ホソカワ粉体技術研究所 | 薬物含有複合粒子の製造方法 |
EP1534202B1 (en) * | 2002-06-05 | 2009-03-11 | University Of Florida Research Foundation, Inc. | Ophthalmic drug delivery system |
US20050255164A1 (en) * | 2002-08-15 | 2005-11-17 | Yunging Liu | Solid nano pharmaceutical formulation and preparation method thereof |
US7811605B2 (en) * | 2002-11-06 | 2010-10-12 | Uluru Inc. | Method of formation of shape-retentive aggregates of gel particles and their uses |
US6928201B2 (en) * | 2002-11-15 | 2005-08-09 | Sunrise Telecom Incorporated | Method and apparatus for providing controllable second-order polarization mode dispersion |
BRPI0409663A (pt) | 2003-04-25 | 2006-04-18 | Penn State Res Found | método e sistema para o envio sistêmico de compostos bioativos derivados de lipìdeo de detenção de crescimento |
EP1641424A4 (en) * | 2003-07-09 | 2007-05-02 | Vaxdesign Corp | PROGRAMMED IMMUNE RESPONSES IMPLEMENTING A VACCINATION NODE |
CA2435632A1 (en) * | 2003-07-21 | 2005-01-21 | Warren Hugh Finlay | Formulation of powder containing nanoparticles for aerosol delivery to the lung |
EP1699549A2 (en) * | 2003-12-19 | 2006-09-13 | SCF Technologies A/S | Systems for preparing fine particles and other substances |
AU2004308757B2 (en) * | 2003-12-22 | 2010-06-17 | Bracco Suisse S.A. | Assembly of gas-filled microvesicle with active component for contrast imaging |
US7610074B2 (en) * | 2004-01-08 | 2009-10-27 | The Board Of Trustees Of The University Of Illinois | Multi-functional plasmon-resonant contrast agents for optical coherence tomography |
-
2006
- 2006-12-14 AU AU2006330627A patent/AU2006330627A1/en not_active Abandoned
- 2006-12-14 EP EP06846628A patent/EP1968550A2/en not_active Withdrawn
- 2006-12-14 MX MX2008007697A patent/MX2008007697A/es active IP Right Grant
- 2006-12-14 WO PCT/US2006/062118 patent/WO2007076295A2/en active Application Filing
- 2006-12-14 CN CN200680051564.1A patent/CN101370479A/zh active Pending
- 2006-12-14 BR BRPI0619938-0A patent/BRPI0619938A2/pt not_active Application Discontinuation
- 2006-12-14 JP JP2008545982A patent/JP2009519975A/ja active Pending
- 2006-12-14 CA CA002633380A patent/CA2633380A1/en not_active Abandoned
- 2006-12-14 US US11/610,986 patent/US7651770B2/en active Active
-
2008
- 2008-06-15 IL IL192159A patent/IL192159A0/en unknown
- 2008-07-07 ZA ZA200805918A patent/ZA200805918B/xx unknown
- 2008-10-30 US US12/261,873 patent/US20090081295A1/en not_active Abandoned
- 2008-10-30 US US12/261,907 patent/US20090053316A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN101370479A (zh) | 2009-02-18 |
IL192159A0 (en) | 2008-12-29 |
AU2006330627A1 (en) | 2007-07-05 |
JP2009519975A (ja) | 2009-05-21 |
CA2633380A1 (en) | 2007-07-05 |
WO2007076295A3 (en) | 2007-11-29 |
WO2007076295A2 (en) | 2007-07-05 |
EP1968550A2 (en) | 2008-09-17 |
MX2008007697A (es) | 2008-09-26 |
US20070172653A1 (en) | 2007-07-26 |
US7651770B2 (en) | 2010-01-26 |
US20090081295A1 (en) | 2009-03-26 |
US20090053316A1 (en) | 2009-02-26 |
BRPI0619938A2 (pt) | 2011-10-25 |
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