ZA200802184B - Use of peptides that bind to TPO receptor - Google Patents

Use of peptides that bind to TPO receptor

Info

Publication number
ZA200802184B
ZA200802184B ZA200802184A ZA200802184A ZA200802184B ZA 200802184 B ZA200802184 B ZA 200802184B ZA 200802184 A ZA200802184 A ZA 200802184A ZA 200802184 A ZA200802184 A ZA 200802184A ZA 200802184 B ZA200802184 B ZA 200802184B
Authority
ZA
South Africa
Prior art keywords
peptides
bind
tpo receptor
tpo
receptor
Prior art date
Application number
ZA200802184A
Other languages
English (en)
Inventor
Brian R Macdonald
Yurkow Edward John
Weis Jeffrey Kenneth
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37734435&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200802184(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of ZA200802184B publication Critical patent/ZA200802184B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
ZA200802184A 2005-08-09 2008-03-07 Use of peptides that bind to TPO receptor ZA200802184B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/200,416 US7723295B2 (en) 2003-08-28 2005-08-09 Peptides and compounds that bind to a receptor

Publications (1)

Publication Number Publication Date
ZA200802184B true ZA200802184B (en) 2009-08-26

Family

ID=37734435

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200802184A ZA200802184B (en) 2005-08-09 2008-03-07 Use of peptides that bind to TPO receptor

Country Status (34)

Country Link
US (1) US7723295B2 (cg-RX-API-DMAC7.html)
EP (1) EP1957517B1 (cg-RX-API-DMAC7.html)
JP (1) JP2009504650A (cg-RX-API-DMAC7.html)
KR (1) KR20080048026A (cg-RX-API-DMAC7.html)
CN (1) CN101287749A (cg-RX-API-DMAC7.html)
AR (1) AR055114A1 (cg-RX-API-DMAC7.html)
AU (1) AU2006280230B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0614647A2 (cg-RX-API-DMAC7.html)
CA (1) CA2618958A1 (cg-RX-API-DMAC7.html)
CR (1) CR9798A (cg-RX-API-DMAC7.html)
CY (1) CY1114032T1 (cg-RX-API-DMAC7.html)
DK (1) DK1957517T3 (cg-RX-API-DMAC7.html)
EA (1) EA200800535A1 (cg-RX-API-DMAC7.html)
EC (1) ECSP088169A (cg-RX-API-DMAC7.html)
ES (1) ES2419005T3 (cg-RX-API-DMAC7.html)
GT (1) GT200600361A (cg-RX-API-DMAC7.html)
HR (1) HRP20130518T1 (cg-RX-API-DMAC7.html)
IL (1) IL189361A (cg-RX-API-DMAC7.html)
JO (1) JO2859B1 (cg-RX-API-DMAC7.html)
MY (1) MY152177A (cg-RX-API-DMAC7.html)
NI (1) NI200800040A (cg-RX-API-DMAC7.html)
NO (1) NO344405B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ565497A (cg-RX-API-DMAC7.html)
PE (1) PE20070416A1 (cg-RX-API-DMAC7.html)
PL (1) PL1957517T3 (cg-RX-API-DMAC7.html)
PT (1) PT1957517E (cg-RX-API-DMAC7.html)
RS (1) RS52802B (cg-RX-API-DMAC7.html)
SI (1) SI1957517T1 (cg-RX-API-DMAC7.html)
SV (1) SV2008002648A (cg-RX-API-DMAC7.html)
TW (1) TWI400081B (cg-RX-API-DMAC7.html)
UA (1) UA96418C2 (cg-RX-API-DMAC7.html)
UY (1) UY29736A1 (cg-RX-API-DMAC7.html)
WO (1) WO2007021572A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200802184B (cg-RX-API-DMAC7.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
NZ566812A (en) 2002-09-18 2009-07-31 Ortho Mcneil Pharm Inc Methods of increasing platelet and hematopoietic stem cell production
US20040149235A1 (en) * 2002-10-04 2004-08-05 Pogue Albert S. Apparatus and method for removal of waste from animal production facilities
US7615533B2 (en) * 2004-08-16 2009-11-10 Janssen Pharmaceutica N.V. TPO peptide compounds for treatment of anemia
WO2007087428A2 (en) * 2006-01-25 2007-08-02 Amgen Inc. Thrombopoietic compounds
KR20110015448A (ko) * 2008-06-03 2011-02-15 얀센 파마슈티카 엔.브이. 암 치료와 관련된 혈액 질환을 예방하기 위한 ｔｐｏ 모방 펩티드
CN103635514B (zh) 2011-06-23 2016-01-20 株式会社岛津制作所 支链型两亲性嵌段聚合物、使用其的分子聚集体及药物输送系统
US12251424B2 (en) 2017-07-26 2025-03-18 Janssen Pharmaceutica Nv Methods of protecting vascular integrity induced by targeted radiation therapy
EP3914272B1 (en) 2019-01-25 2024-03-06 Janssen Pharmaceutica NV Thrombopoietin mimetics for mitigating liver injury and promoting liver hypertrophy, regeneration and cell engraftment in conjunction with radiation and/or radiomimetic treatments
WO2020209920A2 (en) 2019-01-25 2020-10-15 Janssen Pharmaceutica Nv Methods of mitigating toxic effects of vesicants and caustic gas
US20200237872A1 (en) 2019-01-25 2020-07-30 Janssen Pharmaceutica Nv Methods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure
US20240156973A1 (en) * 2021-02-24 2024-05-16 Purdue Research Foundation Osteotropic compositions and uses thereof
EP4408984A1 (en) 2021-10-01 2024-08-07 Janssen Pharmaceutica NV Methods of increasing progenitor cell production
WO2024095178A1 (en) 2022-11-01 2024-05-10 Janssen Pharmaceutica Nv Thrombopoietin mimetic for use in the treatment of acute liver failure

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5326558A (en) * 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
IL96477A0 (en) 1989-12-01 1991-08-16 Amgen Inc Megakaryocyte production
DK167813B1 (da) * 1989-12-07 1993-12-20 Carlbiotech Ltd As Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
US5571508A (en) 1989-12-18 1996-11-05 Amrad Corporation Limited Method for the treatment of thrombocytopenia and pharmaceutical compositions useful therefor
IT1241395B (it) 1990-04-02 1994-01-10 Eniricerche Spa Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria
US5141851A (en) * 1990-04-18 1992-08-25 Board Of Regents, The University Of Texas System Isolated farnesyl protein transferase enzyme
US5250732A (en) * 1991-07-18 1993-10-05 Genentech, Inc. Ketamine analogues for treatment of thrombocytopenia
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
PT644771E (pt) 1992-06-11 2002-12-31 Alkermes Inc Sistema de entrega da droga eritropoietina
EP0673387B1 (en) * 1992-12-11 1999-09-22 University Of Florida Materials and methods for control of pests
AU8124694A (en) 1993-10-29 1995-05-22 Affymax Technologies N.V. In vitro peptide and antibody display libraries
GB2285446B (en) 1994-01-03 1999-07-28 Genentech Inc Thrombopoietin
WO1995021920A1 (en) 1994-02-14 1995-08-17 Zymogenetics, Inc. Hematopoietic protein and materials and methods for making it
WO1995021919A2 (en) 1994-02-14 1995-08-17 Kirin Brewery Company, Limited Protein having tpo activity
EP0723456A1 (en) 1994-02-14 1996-07-31 The University Of Washington Methods for stimulating erythropoiesis using thrombopoietin
SG79882A1 (en) 1994-02-14 2001-04-17 Kirin Brewery Protein having tpo activity
DE69503849T2 (de) 1994-03-31 1999-04-01 Amgen Inc., Thousand Oaks, Calif. Zusammensetzungen und Verfahren zur Anregung des Wachstums und der Differenzierung von Megakaryozyten
US5571686A (en) 1994-04-14 1996-11-05 Massachusetts Institute Of Technology Method of using megapoietin for prolonging the survival & viability of platlets
AU4163196A (en) 1994-11-30 1996-06-19 Zymogenetics Inc. Low molecular weight thrombopoietin
JP3763846B2 (ja) 1995-04-26 2006-04-05 協和醗酵工業株式会社 新規ポリペプチド
US6251864B1 (en) * 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
EP1961760A3 (en) * 1995-06-07 2008-09-03 Glaxo Group Limited Peptides and compounds that bind to a thrombopoietin receptor
US5869451A (en) * 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6060052A (en) * 1995-10-30 2000-05-09 Systemix, Inc. Methods for use of Mpl ligands with primitive human hematopoietic stem cells
US5932546A (en) * 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
EP1223944B1 (en) 1999-09-24 2007-01-03 SmithKline Beecham Corporation Thrombopoietin mimetics
WO2002078612A2 (en) 2001-04-02 2002-10-10 Euro-Celtique S.A. Thrombopoietin (tpo) synthebody for stimulation of platelet production
NZ566812A (en) * 2002-09-18 2009-07-31 Ortho Mcneil Pharm Inc Methods of increasing platelet and hematopoietic stem cell production
EA009286B1 (ru) 2003-08-28 2007-12-28 Орто-Макнейл Фармасьютикал, Инк. Пептиды и соединения, которые связываются с рецептором

Also Published As

Publication number Publication date
CR9798A (es) 2008-09-09
GT200600361A (es) 2007-03-14
EP1957517A2 (en) 2008-08-20
EP1957517B1 (en) 2013-03-20
WO2007021572A2 (en) 2007-02-22
NI200800040A (es) 2010-11-25
US7723295B2 (en) 2010-05-25
RS52802B (sr) 2013-10-31
AR055114A1 (es) 2007-08-08
JO2859B1 (en) 2015-03-15
CY1114032T1 (el) 2016-07-27
MY152177A (en) 2014-08-15
PE20070416A1 (es) 2007-06-13
TWI400081B (zh) 2013-07-01
UY29736A1 (es) 2006-12-29
BRPI0614647A2 (pt) 2011-04-12
HRP20130518T1 (hr) 2013-07-31
US20060040866A1 (en) 2006-02-23
WO2007021572A3 (en) 2007-06-07
AU2006280230A1 (en) 2007-02-22
UA96418C2 (ru) 2011-11-10
IL189361A (en) 2015-11-30
ECSP088169A (es) 2008-03-26
PL1957517T3 (pl) 2013-08-30
NZ565497A (en) 2011-10-28
ES2419005T3 (es) 2013-08-19
NO20081298L (no) 2008-04-23
CN101287749A (zh) 2008-10-15
KR20080048026A (ko) 2008-05-30
PT1957517E (pt) 2013-05-28
SV2008002648A (es) 2008-11-28
AU2006280230B2 (en) 2012-11-08
IL189361A0 (en) 2008-06-05
CA2618958A1 (en) 2007-02-22
EA200800535A1 (ru) 2008-08-29
SI1957517T1 (sl) 2013-07-31
TW200744626A (en) 2007-12-16
DK1957517T3 (da) 2013-04-08
JP2009504650A (ja) 2009-02-05
HK1123811A1 (en) 2009-06-26
NO344405B1 (no) 2019-12-02

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