IL189361A - Doses of compounds that bind to the receptor for use in the treatment of thrombocytopenia - Google Patents

Doses of compounds that bind to the receptor for use in the treatment of thrombocytopenia

Info

Publication number
IL189361A
IL189361A IL189361A IL18936108A IL189361A IL 189361 A IL189361 A IL 189361A IL 189361 A IL189361 A IL 189361A IL 18936108 A IL18936108 A IL 18936108A IL 189361 A IL189361 A IL 189361A
Authority
IL
Israel
Prior art keywords
doses
bind
receptor
compounds
treating thrombocytopenia
Prior art date
Application number
IL189361A
Other languages
English (en)
Hebrew (he)
Other versions
IL189361A0 (en
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37734435&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL189361(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of IL189361A0 publication Critical patent/IL189361A0/en
Publication of IL189361A publication Critical patent/IL189361A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
IL189361A 2005-08-09 2008-02-07 Doses of compounds that bind to the receptor for use in the treatment of thrombocytopenia IL189361A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/200,416 US7723295B2 (en) 2003-08-28 2005-08-09 Peptides and compounds that bind to a receptor
PCT/US2006/030359 WO2007021572A2 (en) 2005-08-09 2006-08-03 Use of peptides that bind to tpo receptor

Publications (2)

Publication Number Publication Date
IL189361A0 IL189361A0 (en) 2008-06-05
IL189361A true IL189361A (en) 2015-11-30

Family

ID=37734435

Family Applications (1)

Application Number Title Priority Date Filing Date
IL189361A IL189361A (en) 2005-08-09 2008-02-07 Doses of compounds that bind to the receptor for use in the treatment of thrombocytopenia

Country Status (34)

Country Link
US (1) US7723295B2 (cg-RX-API-DMAC7.html)
EP (1) EP1957517B1 (cg-RX-API-DMAC7.html)
JP (1) JP2009504650A (cg-RX-API-DMAC7.html)
KR (1) KR20080048026A (cg-RX-API-DMAC7.html)
CN (1) CN101287749A (cg-RX-API-DMAC7.html)
AR (1) AR055114A1 (cg-RX-API-DMAC7.html)
AU (1) AU2006280230B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0614647A2 (cg-RX-API-DMAC7.html)
CA (1) CA2618958A1 (cg-RX-API-DMAC7.html)
CR (1) CR9798A (cg-RX-API-DMAC7.html)
CY (1) CY1114032T1 (cg-RX-API-DMAC7.html)
DK (1) DK1957517T3 (cg-RX-API-DMAC7.html)
EA (1) EA200800535A1 (cg-RX-API-DMAC7.html)
EC (1) ECSP088169A (cg-RX-API-DMAC7.html)
ES (1) ES2419005T3 (cg-RX-API-DMAC7.html)
GT (1) GT200600361A (cg-RX-API-DMAC7.html)
HR (1) HRP20130518T1 (cg-RX-API-DMAC7.html)
IL (1) IL189361A (cg-RX-API-DMAC7.html)
JO (1) JO2859B1 (cg-RX-API-DMAC7.html)
MY (1) MY152177A (cg-RX-API-DMAC7.html)
NI (1) NI200800040A (cg-RX-API-DMAC7.html)
NO (1) NO344405B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ565497A (cg-RX-API-DMAC7.html)
PE (1) PE20070416A1 (cg-RX-API-DMAC7.html)
PL (1) PL1957517T3 (cg-RX-API-DMAC7.html)
PT (1) PT1957517E (cg-RX-API-DMAC7.html)
RS (1) RS52802B (cg-RX-API-DMAC7.html)
SI (1) SI1957517T1 (cg-RX-API-DMAC7.html)
SV (1) SV2008002648A (cg-RX-API-DMAC7.html)
TW (1) TWI400081B (cg-RX-API-DMAC7.html)
UA (1) UA96418C2 (cg-RX-API-DMAC7.html)
UY (1) UY29736A1 (cg-RX-API-DMAC7.html)
WO (1) WO2007021572A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200802184B (cg-RX-API-DMAC7.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091311B2 (en) * 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
NZ566812A (en) 2002-09-18 2009-07-31 Ortho Mcneil Pharm Inc Methods of increasing platelet and hematopoietic stem cell production
US20040149235A1 (en) * 2002-10-04 2004-08-05 Pogue Albert S. Apparatus and method for removal of waste from animal production facilities
US7615533B2 (en) * 2004-08-16 2009-11-10 Janssen Pharmaceutica N.V. TPO peptide compounds for treatment of anemia
WO2007087428A2 (en) * 2006-01-25 2007-08-02 Amgen Inc. Thrombopoietic compounds
KR20110015448A (ko) * 2008-06-03 2011-02-15 얀센 파마슈티카 엔.브이. 암 치료와 관련된 혈액 질환을 예방하기 위한 ｔｐｏ 모방 펩티드
CN103635514B (zh) 2011-06-23 2016-01-20 株式会社岛津制作所 支链型两亲性嵌段聚合物、使用其的分子聚集体及药物输送系统
US12251424B2 (en) 2017-07-26 2025-03-18 Janssen Pharmaceutica Nv Methods of protecting vascular integrity induced by targeted radiation therapy
EP3914272B1 (en) 2019-01-25 2024-03-06 Janssen Pharmaceutica NV Thrombopoietin mimetics for mitigating liver injury and promoting liver hypertrophy, regeneration and cell engraftment in conjunction with radiation and/or radiomimetic treatments
WO2020209920A2 (en) 2019-01-25 2020-10-15 Janssen Pharmaceutica Nv Methods of mitigating toxic effects of vesicants and caustic gas
US20200237872A1 (en) 2019-01-25 2020-07-30 Janssen Pharmaceutica Nv Methods of enhancing protection against organ and vascular injury, hematopoietic recovery and survival in response to total body radiation/chemical exposure
US20240156973A1 (en) * 2021-02-24 2024-05-16 Purdue Research Foundation Osteotropic compositions and uses thereof
EP4408984A1 (en) 2021-10-01 2024-08-07 Janssen Pharmaceutica NV Methods of increasing progenitor cell production
WO2024095178A1 (en) 2022-11-01 2024-05-10 Janssen Pharmaceutica Nv Thrombopoietin mimetic for use in the treatment of acute liver failure

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) * 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5326558A (en) * 1989-08-08 1994-07-05 Genetics Institute, Inc. Megakaryocytopoietic factor
IL96477A0 (en) 1989-12-01 1991-08-16 Amgen Inc Megakaryocyte production
DK167813B1 (da) * 1989-12-07 1993-12-20 Carlbiotech Ltd As Pentapeptidderivat, farmaceutisk acceptable salte heraf, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
US5571508A (en) 1989-12-18 1996-11-05 Amrad Corporation Limited Method for the treatment of thrombocytopenia and pharmaceutical compositions useful therefor
IT1241395B (it) 1990-04-02 1994-01-10 Eniricerche Spa Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria
US5141851A (en) * 1990-04-18 1992-08-25 Board Of Regents, The University Of Texas System Isolated farnesyl protein transferase enzyme
US5250732A (en) * 1991-07-18 1993-10-05 Genentech, Inc. Ketamine analogues for treatment of thrombocytopenia
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
PT644771E (pt) 1992-06-11 2002-12-31 Alkermes Inc Sistema de entrega da droga eritropoietina
EP0673387B1 (en) * 1992-12-11 1999-09-22 University Of Florida Materials and methods for control of pests
AU8124694A (en) 1993-10-29 1995-05-22 Affymax Technologies N.V. In vitro peptide and antibody display libraries
GB2285446B (en) 1994-01-03 1999-07-28 Genentech Inc Thrombopoietin
WO1995021920A1 (en) 1994-02-14 1995-08-17 Zymogenetics, Inc. Hematopoietic protein and materials and methods for making it
WO1995021919A2 (en) 1994-02-14 1995-08-17 Kirin Brewery Company, Limited Protein having tpo activity
EP0723456A1 (en) 1994-02-14 1996-07-31 The University Of Washington Methods for stimulating erythropoiesis using thrombopoietin
SG79882A1 (en) 1994-02-14 2001-04-17 Kirin Brewery Protein having tpo activity
DE69503849T2 (de) 1994-03-31 1999-04-01 Amgen Inc., Thousand Oaks, Calif. Zusammensetzungen und Verfahren zur Anregung des Wachstums und der Differenzierung von Megakaryozyten
US5571686A (en) 1994-04-14 1996-11-05 Massachusetts Institute Of Technology Method of using megapoietin for prolonging the survival & viability of platlets
AU4163196A (en) 1994-11-30 1996-06-19 Zymogenetics Inc. Low molecular weight thrombopoietin
JP3763846B2 (ja) 1995-04-26 2006-04-05 協和醗酵工業株式会社 新規ポリペプチド
US6251864B1 (en) * 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
EP1961760A3 (en) * 1995-06-07 2008-09-03 Glaxo Group Limited Peptides and compounds that bind to a thrombopoietin receptor
US5869451A (en) * 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6060052A (en) * 1995-10-30 2000-05-09 Systemix, Inc. Methods for use of Mpl ligands with primitive human hematopoietic stem cells
US5932546A (en) * 1996-10-04 1999-08-03 Glaxo Wellcome Inc. Peptides and compounds that bind to the thrombopoietin receptor
EP1223944B1 (en) 1999-09-24 2007-01-03 SmithKline Beecham Corporation Thrombopoietin mimetics
WO2002078612A2 (en) 2001-04-02 2002-10-10 Euro-Celtique S.A. Thrombopoietin (tpo) synthebody for stimulation of platelet production
NZ566812A (en) * 2002-09-18 2009-07-31 Ortho Mcneil Pharm Inc Methods of increasing platelet and hematopoietic stem cell production
EA009286B1 (ru) 2003-08-28 2007-12-28 Орто-Макнейл Фармасьютикал, Инк. Пептиды и соединения, которые связываются с рецептором

Also Published As

Publication number Publication date
CR9798A (es) 2008-09-09
GT200600361A (es) 2007-03-14
EP1957517A2 (en) 2008-08-20
EP1957517B1 (en) 2013-03-20
WO2007021572A2 (en) 2007-02-22
NI200800040A (es) 2010-11-25
US7723295B2 (en) 2010-05-25
RS52802B (sr) 2013-10-31
ZA200802184B (en) 2009-08-26
AR055114A1 (es) 2007-08-08
JO2859B1 (en) 2015-03-15
CY1114032T1 (el) 2016-07-27
MY152177A (en) 2014-08-15
PE20070416A1 (es) 2007-06-13
TWI400081B (zh) 2013-07-01
UY29736A1 (es) 2006-12-29
BRPI0614647A2 (pt) 2011-04-12
HRP20130518T1 (hr) 2013-07-31
US20060040866A1 (en) 2006-02-23
WO2007021572A3 (en) 2007-06-07
AU2006280230A1 (en) 2007-02-22
UA96418C2 (ru) 2011-11-10
ECSP088169A (es) 2008-03-26
PL1957517T3 (pl) 2013-08-30
NZ565497A (en) 2011-10-28
ES2419005T3 (es) 2013-08-19
NO20081298L (no) 2008-04-23
CN101287749A (zh) 2008-10-15
KR20080048026A (ko) 2008-05-30
PT1957517E (pt) 2013-05-28
SV2008002648A (es) 2008-11-28
AU2006280230B2 (en) 2012-11-08
IL189361A0 (en) 2008-06-05
CA2618958A1 (en) 2007-02-22
EA200800535A1 (ru) 2008-08-29
SI1957517T1 (sl) 2013-07-31
TW200744626A (en) 2007-12-16
DK1957517T3 (da) 2013-04-08
JP2009504650A (ja) 2009-02-05
HK1123811A1 (en) 2009-06-26
NO344405B1 (no) 2019-12-02

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