ZA200707678B - Amino acid derivatives - Google Patents

Amino acid derivatives

Info

Publication number
ZA200707678B
ZA200707678B ZA200707678A ZA200707678A ZA200707678B ZA 200707678 B ZA200707678 B ZA 200707678B ZA 200707678 A ZA200707678 A ZA 200707678A ZA 200707678 A ZA200707678 A ZA 200707678A ZA 200707678 B ZA200707678 B ZA 200707678B
Authority
ZA
South Africa
Prior art keywords
amino acid
acid derivatives
derivatives
amino
acid
Prior art date
Application number
ZA200707678A
Other languages
English (en)
Inventor
Graham Shelley Rene
Mantell Simon John
Rawson David James
Schwarz Jacob Bradley
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36677128&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200707678(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of ZA200707678B publication Critical patent/ZA200707678B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401Proline; Derivatives thereof, e.g. captopril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/4172Imidazole-alkanecarboxylic acids, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
ZA200707678A 2005-04-28 2007-09-06 Amino acid derivatives ZA200707678B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67602505P 2005-04-28 2005-04-28

Publications (1)

Publication Number Publication Date
ZA200707678B true ZA200707678B (en) 2009-08-26

Family

ID=36677128

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200707678A ZA200707678B (en) 2005-04-28 2007-09-06 Amino acid derivatives

Country Status (27)

Country Link
US (1) US7612226B2 (es)
EP (1) EP1879567A1 (es)
JP (2) JP4173909B1 (es)
KR (1) KR100925900B1 (es)
CN (1) CN101166524B (es)
AP (1) AP2007004161A0 (es)
AR (1) AR054441A1 (es)
AU (1) AU2006238933B2 (es)
BR (1) BRPI0609879A2 (es)
CA (1) CA2606353C (es)
CR (1) CR9472A (es)
DO (1) DOP2006000095A (es)
EA (1) EA200701852A1 (es)
GT (1) GT200600178A (es)
HK (1) HK1116417A1 (es)
IL (1) IL185790A0 (es)
MA (1) MA29408B1 (es)
MX (1) MX2007010978A (es)
NL (1) NL1031705C2 (es)
NO (1) NO20076000L (es)
PE (1) PE20061435A1 (es)
SV (1) SV2008002512A (es)
TN (1) TNSN07400A1 (es)
TW (1) TW200719889A (es)
UY (1) UY29498A1 (es)
WO (1) WO2006114707A1 (es)
ZA (1) ZA200707678B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1094757C (zh) 1996-07-24 2002-11-27 沃尼尔·朗伯公司 用于治疗疼痛的异丁基γ-氨基丁酸及其衍生物
AP2007004161A0 (en) * 2005-04-28 2007-10-31 Pfizer Ltd Amino acid derivatives
EP1951655A2 (en) * 2005-11-17 2008-08-06 Pfizer Limited Amino acid derivatives
US8278355B2 (en) 2006-09-12 2012-10-02 Therexcell Pharma Inc. Isovaline for treatment of pain
CN101195583B (zh) * 2006-12-04 2012-07-04 四川抗菌素工业研究所有限公司 一种光学纯米那普仑及其盐的制备方法
ES2706875T3 (es) * 2008-09-09 2019-04-01 Hoffmann La Roche Polimorfos de acilsulfonamidas
JP2012176902A (ja) * 2011-02-25 2012-09-13 Tosoh F-Tech Inc 新規な光学活性含フッ素化合物、その製造方法及びそれを用いた光学活性3,3,3−トリフルオロアラニンの製造方法
AT514349B1 (de) * 2013-06-12 2018-05-15 Red Bull Gmbh Alpha-alkylierte Aminosäuren (AAAAs)

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB504209A (en) 1937-12-14 1939-04-21 Pirelli General Cable Works Improvements in or relating to electric cables
BR6239521D0 (pt) * 1961-08-09 1973-06-14 Merck & Co Inc Processo de preparacao de novos amino acidos
FR2586562B1 (fr) 1985-09-02 1989-03-10 Inst Nat Sante Rech Med Composition pharmaceutique contenant de l'a-methylhistamine
DE3811256A1 (de) 1988-04-02 1989-10-19 Hoechst Ag (alpha)-trifluormethylaminosaeure-derivate, verfahren zur herstellung von (alpha)-trifluormethylaminosaeure-derivaten und ihre verwendung als arzneimittel
WO1991001724A1 (en) 1989-07-27 1991-02-21 G.D. Searle & Co. Renal-selective prodrugs for the treatment of hypertension
FR2681067B1 (fr) * 1991-09-10 1993-12-17 Elf Sanofi Derives heterocycliques n-substitues, leur preparation, les compositions pharmaceutiques en contenant.
JPH042899A (ja) 1990-04-16 1992-01-07 Arakawa Chem Ind Co Ltd 紙用サイズ剤および該サイズ剤を用いる紙サイジング方法
FR2661909B1 (fr) 1990-05-09 1997-08-14 Inst Nat Sante Rech Med Nouveaux composes agonistes du recepteur h3 de l'histamine a usage therapeutique, compositions pharmaceutiques agissant comme agonistes dudit recepteur et procede de preparation.
JPH051002A (ja) 1991-02-15 1993-01-08 Nikko Kyodo Co Ltd α−アミノ酸の製造方法
CA2068038A1 (en) 1991-05-08 1992-11-09 Christopher Yee Enzymatic resolution of .alpha.-tertiary carboxylic acid esters
US5993775A (en) 1991-11-27 1999-11-30 Diatide, Inc. Radioactively labeled peptides comprising a single thiol moiety
GB9200210D0 (en) 1992-01-07 1992-02-26 British Bio Technology Compounds
AU674553B2 (en) 1992-10-14 1997-01-02 Merck & Co., Inc. Fibrinogen receptor antagonists
US5362747A (en) 1992-11-25 1994-11-08 Abbott Laboratories 2-nitroaryl and 2-cyanoaryl compounds as regulators of nitric oxide synthase
GB9325360D0 (en) 1993-12-10 1994-02-16 Univ Bristol Organic compounds
GB9325368D0 (en) 1993-12-10 1994-02-16 Univ Bristol Organic compounds
IS4261A (is) 1994-02-21 1995-08-22 Astra Aktiebolag Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra
DE19533617A1 (de) 1995-09-11 1997-03-13 Degussa Neues Verfahren zur Herstellung von optisch aktiven alpha-Aminosäuren und alpha-Aminosäure-Derivaten
ATE225343T1 (de) 1995-12-20 2002-10-15 Hoffmann La Roche Matrix-metalloprotease inhibitoren
WO1998014208A1 (en) 1996-09-30 1998-04-09 President And Fellows Of Harvard College Reactive ligands and covalent ligand-protein complexes
US5962523A (en) 1996-10-25 1999-10-05 Discovery Laboratories, Inc. Methods of using butyric acid derivatives to protect against hair loss
JPH10333511A (ja) 1997-05-30 1998-12-18 Ricoh Co Ltd 画像除去促進液、該画像除去促進液を用いた被記録材の再生方法及び再生装置
JP4205191B2 (ja) 1997-12-26 2009-01-07 ダイセル化学工業株式会社 α−アミノニトリル誘導体及びα−アミノ酸の製造方法
CN1235559C (zh) 1998-03-11 2006-01-11 株式会社创研 皮肤水分保持能力的改善剂
EP1071655A1 (en) * 1998-04-17 2001-01-31 Kenneth Curry Cubane derivatives as metabotropic glutamate receptor antagonists and process for their preparation
HUP0104646A3 (en) 1998-12-18 2004-05-28 Novo Nordisk As Fused 1,2,4-thiadiazine derivatives, their preparation and use
JP2002533318A (ja) 1998-12-22 2002-10-08 ニューロサーチ、アクティーゼルスカブ イオンチャネル調節剤
FR2788271B1 (fr) 1999-01-07 2001-02-09 Rhone Poulenc Agrochimie Nouveau procede de preparation d'aminoacides chiraux
EP1144360B1 (en) 1999-01-22 2005-04-27 PharmaCore, Inc, A method for the synthesis of compounds of formula 1 and derivatives thereof
EP1149843A4 (en) 1999-01-28 2012-06-06 Chugai Pharmaceutical Co Ltd SUBSTITUTED PHENETHYLAMINE DERIVATIVES
FR2791982B1 (fr) 1999-04-06 2002-12-27 Inst Nat Sante Rech Med Inhibiteurs de lta4 hydrolase et leurs applications therapeutiques.
WO2001009117A1 (en) 1999-07-29 2001-02-08 Allellix Neuroscience Inc. Tricyclic compounds as glycine transport inhibitors
FR2796943A1 (fr) 1999-07-30 2001-02-02 Aventis Pharma Sa Derives de benzoxazinnes, leur procede de preparation et leur utilisation en therapeutique
WO2001017944A1 (fr) 1999-09-07 2001-03-15 Mitsubishi Rayon Co., Ltd. Procede relatif a l'elaboration d'aminoalcool optiquement actif
EP1210933A4 (en) 1999-09-07 2003-01-22 Soken Kk SKIN CARE AGENTS
JP2001081013A (ja) 1999-09-10 2001-03-27 Soken Kk 毛髪健全化剤
US7300775B2 (en) 1999-12-29 2007-11-27 Verenium Corporation Methods for producing α-substituted carboxylic acids using nitrilases and strecker reagents
US6656958B2 (en) 2000-02-02 2003-12-02 Abbott Laboratories Substituted pyridine compounds useful for controlling chemical synaptic transmission
DE10121026A1 (de) 2000-05-05 2002-02-07 Basf Ag Verfahren zur Herstellung von Aldehyden
DE10121028A1 (de) 2000-05-05 2002-01-31 Basf Ag Verfahren zur Herstellung von Aldehyden
US6949658B2 (en) 2000-05-18 2005-09-27 Mitsubishi Rayon Co., Ltd. Process for producing optically active α-amino acid and optically active α-amino acid amide
WO2003011799A1 (en) 2000-07-31 2003-02-13 Brandeis University Kinetic resolutions of chirat 3- and 3-substituted carboxylic acids
DE10048715A1 (de) 2000-09-30 2004-05-19 Grünenthal GmbH Verwendung von Aminosäure zur Behandlung von Schmerz
AUPR406901A0 (en) 2001-03-29 2001-04-26 La Trobe University Insecticide and method of controlling insects
JP4715058B2 (ja) 2001-08-02 2011-07-06 Jsr株式会社 感放射性樹脂組成物
JP2003221328A (ja) 2002-01-29 2003-08-05 Soken Kk 皮膚健全化剤
US6875883B2 (en) 2002-05-15 2005-04-05 Genzyme Corporation Synthesis of benzonitriles from substituted benzaldehyde
AU2003252536A1 (en) 2002-08-01 2004-02-23 Basf Aktiengesellschaft Pesticidal fluoroalkene derivatives
US20060025471A1 (en) * 2002-09-13 2006-02-02 Kenneth Curry Xanthenyl cubane analogs with activity at the metabotropic glutamate receptors
EP1584690A1 (en) 2003-01-10 2005-10-12 Kaneka Corporation PROCESS FOR PRODUCING OPTICALLY ACTIVE a-METHYLCYSTEINE DERIVATIVE
JP2005060311A (ja) 2003-08-13 2005-03-10 Mochida Pharmaceut Co Ltd N−(ベンゾイル)アミノ酸誘導体を有効成分とするニューロパシー性疼痛治療剤
GB0322140D0 (en) * 2003-09-22 2003-10-22 Pfizer Ltd Combinations
WO2005044780A1 (ja) 2003-11-10 2005-05-19 Kyorin Pharmaceutical Co., Ltd. アミノカルボン酸誘導体とその付加塩及びs1p受容体調節剤
US20090215895A1 (en) * 2004-01-30 2009-08-27 Peplin Biolipids Pty Ltd Therapeutic and carrier molecules
GB0405289D0 (en) 2004-03-09 2004-04-21 Novartis Ag Organic compounds
CA2599662A1 (en) 2005-03-01 2006-09-08 Pfizer Limited Use of pde7 inhibitors for the treatment of neuropathic pain
TW200642687A (en) * 2005-03-01 2006-12-16 Pfizer Ltd Combinations comprising α-2-δ ligands
CN101160285A (zh) * 2005-03-17 2008-04-09 辉瑞大药厂 适用于治疗疼痛的n-(n-磺酰氨基甲基)环丙烷甲酰胺衍生物
AP2007004161A0 (en) * 2005-04-28 2007-10-31 Pfizer Ltd Amino acid derivatives
EA200801145A1 (ru) * 2005-12-02 2008-10-30 Пфайзер Лимитед Спироциклические производные хиназолина в качестве ингибиторов pde7

Also Published As

Publication number Publication date
CA2606353C (en) 2011-11-22
CR9472A (es) 2007-12-04
NL1031705C2 (nl) 2007-05-08
AP2007004161A0 (en) 2007-10-31
JP2008539221A (ja) 2008-11-13
TNSN07400A1 (fr) 2009-03-17
JP4173909B1 (ja) 2008-10-29
US20060247291A1 (en) 2006-11-02
EP1879567A1 (en) 2008-01-23
KR100925900B1 (ko) 2009-11-09
SV2008002512A (es) 2008-02-08
MX2007010978A (es) 2007-09-19
WO2006114707A1 (en) 2006-11-02
KR20070116663A (ko) 2007-12-10
AU2006238933B2 (en) 2011-12-01
IL185790A0 (en) 2008-01-06
GT200600178A (es) 2006-11-28
MA29408B1 (fr) 2008-04-01
US7612226B2 (en) 2009-11-03
AR054441A1 (es) 2007-06-27
CN101166524B (zh) 2010-12-22
NL1031705A1 (nl) 2006-11-01
DOP2006000095A (es) 2006-10-15
CA2606353A1 (en) 2006-11-02
EA200701852A1 (ru) 2008-04-28
HK1116417A1 (en) 2008-12-24
JP2009040767A (ja) 2009-02-26
NO20076000L (no) 2008-01-28
UY29498A1 (es) 2006-11-30
BRPI0609879A2 (pt) 2010-05-11
TW200719889A (en) 2007-06-01
PE20061435A1 (es) 2007-02-03
AU2006238933A1 (en) 2006-11-02
CN101166524A (zh) 2008-04-23

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