ZA200607057B - Sulfated oligosaccharide derivatives - Google Patents

Sulfated oligosaccharide derivatives

Info

Publication number
ZA200607057B
ZA200607057B ZA2006/07057A ZA200607057A ZA200607057B ZA 200607057 B ZA200607057 B ZA 200607057B ZA 2006/07057 A ZA2006/07057 A ZA 2006/07057A ZA 200607057 A ZA200607057 A ZA 200607057A ZA 200607057 B ZA200607057 B ZA 200607057B
Authority
ZA
South Africa
Prior art keywords
oligosaccharide derivatives
sulfated oligosaccharide
sulfated
derivatives
oligosaccharide
Prior art date
Application number
ZA2006/07057A
Other languages
English (en)
Inventor
Vito Ferro
Tomislav Karoli
Jon Krueger Fairweather
Ligong Liu
Original Assignee
Progen Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2004901103A external-priority patent/AU2004901103A0/en
Application filed by Progen Ind Ltd filed Critical Progen Ind Ltd
Publication of ZA200607057B publication Critical patent/ZA200607057B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/04—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Transplantation (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
ZA2006/07057A 2004-03-04 2006-08-23 Sulfated oligosaccharide derivatives ZA200607057B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2004901103A AU2004901103A0 (en) 2004-03-04 Sulfated Oligosaccharide Derivatives
PCT/AU2005/000314 WO2005085264A1 (en) 2004-03-04 2005-03-04 Sulfated oligosaccharide derivatives

Publications (1)

Publication Number Publication Date
ZA200607057B true ZA200607057B (en) 2008-04-30

Family

ID=34916868

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2006/07057A ZA200607057B (en) 2004-03-04 2006-08-23 Sulfated oligosaccharide derivatives

Country Status (17)

Country Link
US (2) US7875592B2 (enExample)
EP (1) EP1720889B1 (enExample)
JP (1) JP5139797B2 (enExample)
KR (1) KR101156273B1 (enExample)
CN (3) CN1989146A (enExample)
AU (1) AU2005219456B2 (enExample)
BR (1) BRPI0508144A (enExample)
CA (1) CA2557989C (enExample)
ES (1) ES2531880T3 (enExample)
HK (1) HK1199263A1 (enExample)
IL (1) IL177870A (enExample)
MX (1) MXPA06010049A (enExample)
NO (1) NO338461B1 (enExample)
RU (1) RU2392281C2 (enExample)
TW (1) TWI426080B (enExample)
WO (1) WO2005085264A1 (enExample)
ZA (1) ZA200607057B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2392281C2 (ru) * 2004-03-04 2010-06-20 Проджен Фармасьютикалз Лимитед Сульфатированные производные олигосахаридов
JP2008534519A (ja) * 2005-04-01 2008-08-28 クリストファー・リチャード・パリッシュ グルコサミンオリゴ糖などのｎｏｄ因子を用いる血管新生の調節
ES2584927T7 (es) * 2007-10-16 2020-11-05 Progen Pg500 Series Pty Ltd Derivados de oligosacáridos sulfatados novedosos
JP2011526925A (ja) * 2008-07-01 2011-10-20 ザカロン ファーマシューティカルズ，インク． ヘパラン硫酸阻害剤
EP2149580A1 (en) 2008-07-15 2010-02-03 Istituto Scientifico di Chimica E Biochimica "G Ronzoni Mimetics of sulfated oligosaccharides
CN101591401A (zh) * 2009-02-27 2009-12-02 江南大学 一种制备高活性低分子量肝素的方法
JP5701498B2 (ja) * 2009-12-01 2015-04-15 公益財団法人微生物化学研究会 炎症性細胞からのヘパラナーゼの放出抑制剤、抗炎症剤、及び薬用組成物
CN107362168A (zh) * 2011-06-09 2017-11-21 基亚生物科技股份有限公司 用于抑制肝癌复发、恶化或转移之医药组成物
EP3116887B1 (en) 2014-03-13 2021-02-17 Universität Basel Carbohydrate ligands that bind to igm antibodies against myelin-associated glycoprotein
CN105017341B (zh) * 2014-04-22 2018-05-15 华东师范大学 硫酸化岩藻-半乳四糖及其制备方法和应用
CN105001278B (zh) * 2015-06-19 2018-07-06 天津红日药业股份有限公司 一种磺达肝癸钠二糖中间体片段的合成方法
CN104876979B (zh) * 2015-06-19 2018-10-09 天津红日药业股份有限公司 一种具有抗Xa因子活性的磺酸化五糖化合物
JP6849667B2 (ja) 2015-09-16 2021-03-24 ウニヴェルズィテート バーゼル スフィンゴ糖脂質の糖鎖エピトープに対する抗体に結合する炭水化物リガンド
JP2016199579A (ja) * 2016-07-08 2016-12-01 基亜生物科技股▲ふん▼有限公司Ｍｅｄｉｇｅｎ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐ． 肝癌の再発、悪化または転移の抑制に用いる医薬組成物
WO2018103680A1 (zh) * 2016-12-10 2018-06-14 扬州蓝色生物医药科技有限公司 甘露寡聚糖类化合物及其作为抗rna病毒药物的应用
JP2020503377A (ja) 2016-12-13 2020-01-30 ベータ セラピューティクス プロプライアタリー リミティド ヘパラナーゼ阻害剤及びそれの使用
US11787783B2 (en) 2016-12-13 2023-10-17 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof
WO2018107244A1 (en) 2016-12-15 2018-06-21 Progen Pg500 Series Pty Ltd Composition and uses thereof
US10842804B2 (en) * 2017-03-01 2020-11-24 Medigen Biotechnology Corporation Muparfostat for use in treating patients with hepatitis virus-related hepatocellular carcinoma after surgical resection
KR102377358B1 (ko) 2017-10-16 2022-03-23 삼성전자주식회사 반도체 메모리 소자 및 그 제조 방법
JP7359396B2 (ja) * 2017-12-15 2023-10-11 ジ・オーストラリアン・ナショナル・ユニヴァーシティ 細胞外ヒストンによって媒介される病理を処置及び予防するための化合物
JP6619830B2 (ja) * 2018-02-22 2019-12-11 基亜生物科技股▲ふん▼有限公司Ｍｅｄｉｇｅｎ Ｂｉｏｔｅｃｈｎｏｌｏｇｙ Ｃｏｒｐ． 肝癌の再発、悪化または転移の抑制に用いる医薬組成物
CN109762032A (zh) * 2019-01-16 2019-05-17 天津科技大学 一种磺酸化路易斯x三糖及其合成方法和应用
SG11202109032SA (en) * 2019-02-25 2021-09-29 Univ Australian National Compounds for treating and preventing net associated complications
CN116813675B (zh) * 2023-08-23 2023-11-24 北京远大九和药业有限公司 一种化合物晶型及其制备、组合物和用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989003684A1 (fr) 1987-10-30 1989-05-05 Chugai Seiyaku Kabushiki Kaisha Agent anti-vih
FR2704226B1 (fr) * 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5739115A (en) 1993-10-07 1998-04-14 Glycomed Incorporated Sulfated maltooligosaccharides with heparin-like properties
JPH09503510A (ja) * 1993-10-07 1997-04-08 グリコメド・インコーポレイテッド ヘパリン様特性を有する高硫酸化マルトオリゴ糖
AUPN261895A0 (en) 1995-04-28 1995-05-18 Australian National University, The Preparation and use of sulfated oligosaccharides
RU2193039C2 (ru) * 1995-04-28 2002-11-20 Такара Сузо Ко., Лтд. Соединение сахара
JPH09183789A (ja) * 1995-10-31 1997-07-15 Sanwa Kagaku Kenkyusho Co Ltd 新規な硫酸化及び燐酸化糖誘導体、その製法及び用途
IL120722A (en) * 1996-05-08 1999-07-14 Akzo Nobel Nv Polysulfated tetrasaccharide derivatives and pharmaceutical compositions containing them
AUPO556297A0 (en) 1997-03-11 1997-04-10 Australian National University, The Sulfated oligosaccharides having anticoagulant/ antithrombotic activity
IL126893A (en) * 1997-11-19 2003-05-29 Akzo Nobel Nv Sulfated pentasaccharide derivatives and pharmaceutical compositions containing them
FR2773801B1 (fr) * 1998-01-19 2000-05-12 Sanofi Sa Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant
CN1450075A (zh) * 2002-04-11 2003-10-22 中国科学院生态环境研究中心 一类寡糖及其硫酸化产物和它们的制备方法及含该寡糖的药物组合物
RU2392281C2 (ru) * 2004-03-04 2010-06-20 Проджен Фармасьютикалз Лимитед Сульфатированные производные олигосахаридов

Also Published As

Publication number Publication date
US7875592B2 (en) 2011-01-25
BRPI0508144A (pt) 2007-07-24
WO2005085264A1 (en) 2005-09-15
AU2005219456B2 (en) 2011-04-07
CA2557989C (en) 2013-04-23
HK1199263A1 (en) 2015-06-26
US20110130354A1 (en) 2011-06-02
KR101156273B1 (ko) 2012-06-13
EP1720889B1 (en) 2014-11-26
CN103788141A (zh) 2014-05-14
NO338461B1 (no) 2016-08-15
TW200602351A (en) 2006-01-16
AU2005219456A1 (en) 2005-09-15
CN104119404A (zh) 2014-10-29
CN1989146A (zh) 2007-06-27
IL177870A (en) 2011-08-31
MXPA06010049A (es) 2007-04-10
JP5139797B2 (ja) 2013-02-06
RU2006134972A (ru) 2008-04-10
US20070185037A1 (en) 2007-08-09
NO20064489L (no) 2006-11-27
US8173606B2 (en) 2012-05-08
CN103788141B (zh) 2016-08-17
CA2557989A1 (en) 2005-09-15
EP1720889A4 (en) 2008-03-19
EP1720889A1 (en) 2006-11-15
TWI426080B (zh) 2014-02-11
IL177870A0 (en) 2006-12-31
ES2531880T3 (es) 2015-03-20
RU2392281C2 (ru) 2010-06-20
JP2007526257A (ja) 2007-09-13
KR20070007815A (ko) 2007-01-16

Similar Documents

Publication Publication Date Title
ZA200607057B (en) Sulfated oligosaccharide derivatives
IL205143A (en) Sulphate oligosaccharides
TWI369356B (en) Tetrahydropyridoindole derivatives
EP1878727A4 (en) 2-AMINOQUINAZOLINE DERIVATIVES
IL185674A0 (en) 1-benzylindole-2-carboxamide derivatives
IL192092A0 (en) Aryl-isoxazolo-4-yl-oxadiazole derivatives
IL180481A0 (en) Aryl-pyridine derivatives
HUS2000022I1 (hu) Tiglien-3-on származékok
ZA200610102B (en) Pyrrazolo-pyrimidine derivatives
ZA200802088B (en) 4-Phenyl-6-substitued-pyrimidine-2-carbonitrile derivatives
ZA200802421B (en) 1-Acyldihydropyrazol derivatives
IL182585A0 (en) Imidazo-benzodiazepine derivatives
ZA200804257B (en) Azaindole-2-carboxamide derivatives
IL192235A0 (en) Aryl-isoxazol-4-yl-imidazole derivatives
IL191138A0 (en) Pyrazoloisoquinoline derivatives
ZA200702066B (en) Halogenated benzmide derivatives
GB0414272D0 (en) OsK1 derivatives
IL177204A0 (en) Novel 4-benzimidazol -2-ylpyridazin -3- one derivatives
IL179444A0 (en) 4-phenyl-pyrimidine-2-carbonitrile derivatives
TWI346109B (en) 4-amino-5-cyanopyrimidine derivatives
IL182001A0 (en) 2-acylaminothiazole derivatives
GB0511410D0 (en) Benzotrizepinone derivatives
ZA200706577B (en) Dihydroimidazothiazole derivatives
AU2004901103A0 (en) Sulfated Oligosaccharide Derivatives
HU0401553D0 (en) Sulfated oligosaccharides