KR101156273B1 - 황산화 올리고사카라이드 유도체 - Google Patents

황산화 올리고사카라이드 유도체 Download PDF

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KR101156273B1
KR101156273B1 KR1020067020704A KR20067020704A KR101156273B1 KR 101156273 B1 KR101156273 B1 KR 101156273B1 KR 1020067020704 A KR1020067020704 A KR 1020067020704A KR 20067020704 A KR20067020704 A KR 20067020704A KR 101156273 B1 KR101156273 B1 KR 101156273B1
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sulfono
tri
mannopyranosyl
aryl
tetra
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KR20070007815A (ko
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비토 페로
존 크루거 페어웨더
토미슬라브 카롤리
리공 리우
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프로젠 파마슈티칼즈 리미티드
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    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
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    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
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    • A61P35/04Antineoplastic agents specific for metastasis
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    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
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    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
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    • C07H5/00Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium

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KR1020067020704A 2004-03-04 2005-03-04 황산화 올리고사카라이드 유도체 Expired - Fee Related KR101156273B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2004901103A AU2004901103A0 (en) 2004-03-04 Sulfated Oligosaccharide Derivatives
AU2004901103 2004-03-04
PCT/AU2005/000314 WO2005085264A1 (en) 2004-03-04 2005-03-04 Sulfated oligosaccharide derivatives

Publications (2)

Publication Number Publication Date
KR20070007815A KR20070007815A (ko) 2007-01-16
KR101156273B1 true KR101156273B1 (ko) 2012-06-13

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US (2) US7875592B2 (enExample)
EP (1) EP1720889B1 (enExample)
JP (1) JP5139797B2 (enExample)
KR (1) KR101156273B1 (enExample)
CN (3) CN1989146A (enExample)
AU (1) AU2005219456B2 (enExample)
BR (1) BRPI0508144A (enExample)
CA (1) CA2557989C (enExample)
ES (1) ES2531880T3 (enExample)
HK (1) HK1199263A1 (enExample)
IL (1) IL177870A (enExample)
MX (1) MXPA06010049A (enExample)
NO (1) NO338461B1 (enExample)
RU (1) RU2392281C2 (enExample)
TW (1) TWI426080B (enExample)
WO (1) WO2005085264A1 (enExample)
ZA (1) ZA200607057B (enExample)

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RU2392281C2 (ru) * 2004-03-04 2010-06-20 Проджен Фармасьютикалз Лимитед Сульфатированные производные олигосахаридов
JP2008534519A (ja) * 2005-04-01 2008-08-28 クリストファー・リチャード・パリッシュ グルコサミンオリゴ糖などのnod因子を用いる血管新生の調節
ES2584927T7 (es) * 2007-10-16 2020-11-05 Progen Pg500 Series Pty Ltd Derivados de oligosacáridos sulfatados novedosos
JP2011526925A (ja) * 2008-07-01 2011-10-20 ザカロン ファーマシューティカルズ,インク. ヘパラン硫酸阻害剤
EP2149580A1 (en) 2008-07-15 2010-02-03 Istituto Scientifico di Chimica E Biochimica "G Ronzoni Mimetics of sulfated oligosaccharides
CN101591401A (zh) * 2009-02-27 2009-12-02 江南大学 一种制备高活性低分子量肝素的方法
JP5701498B2 (ja) * 2009-12-01 2015-04-15 公益財団法人微生物化学研究会 炎症性細胞からのヘパラナーゼの放出抑制剤、抗炎症剤、及び薬用組成物
CN107362168A (zh) * 2011-06-09 2017-11-21 基亚生物科技股份有限公司 用于抑制肝癌复发、恶化或转移之医药组成物
EP3116887B1 (en) 2014-03-13 2021-02-17 Universität Basel Carbohydrate ligands that bind to igm antibodies against myelin-associated glycoprotein
CN105017341B (zh) * 2014-04-22 2018-05-15 华东师范大学 硫酸化岩藻-半乳四糖及其制备方法和应用
CN105001278B (zh) * 2015-06-19 2018-07-06 天津红日药业股份有限公司 一种磺达肝癸钠二糖中间体片段的合成方法
CN104876979B (zh) * 2015-06-19 2018-10-09 天津红日药业股份有限公司 一种具有抗Xa因子活性的磺酸化五糖化合物
JP6849667B2 (ja) 2015-09-16 2021-03-24 ウニヴェルズィテート バーゼル スフィンゴ糖脂質の糖鎖エピトープに対する抗体に結合する炭水化物リガンド
JP2016199579A (ja) * 2016-07-08 2016-12-01 基亜生物科技股▲ふん▼有限公司Medigen Biotechnology Corp. 肝癌の再発、悪化または転移の抑制に用いる医薬組成物
WO2018103680A1 (zh) * 2016-12-10 2018-06-14 扬州蓝色生物医药科技有限公司 甘露寡聚糖类化合物及其作为抗rna病毒药物的应用
JP2020503377A (ja) 2016-12-13 2020-01-30 ベータ セラピューティクス プロプライアタリー リミティド ヘパラナーゼ阻害剤及びそれの使用
US11787783B2 (en) 2016-12-13 2023-10-17 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof
WO2018107244A1 (en) 2016-12-15 2018-06-21 Progen Pg500 Series Pty Ltd Composition and uses thereof
US10842804B2 (en) * 2017-03-01 2020-11-24 Medigen Biotechnology Corporation Muparfostat for use in treating patients with hepatitis virus-related hepatocellular carcinoma after surgical resection
KR102377358B1 (ko) 2017-10-16 2022-03-23 삼성전자주식회사 반도체 메모리 소자 및 그 제조 방법
JP7359396B2 (ja) * 2017-12-15 2023-10-11 ジ・オーストラリアン・ナショナル・ユニヴァーシティ 細胞外ヒストンによって媒介される病理を処置及び予防するための化合物
JP6619830B2 (ja) * 2018-02-22 2019-12-11 基亜生物科技股▲ふん▼有限公司Medigen Biotechnology Corp. 肝癌の再発、悪化または転移の抑制に用いる医薬組成物
CN109762032A (zh) * 2019-01-16 2019-05-17 天津科技大学 一种磺酸化路易斯x三糖及其合成方法和应用
SG11202109032SA (en) * 2019-02-25 2021-09-29 Univ Australian National Compounds for treating and preventing net associated complications
CN116813675B (zh) * 2023-08-23 2023-11-24 北京远大九和药业有限公司 一种化合物晶型及其制备、组合物和用途

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WO1996009828A1 (en) * 1994-09-26 1996-04-04 Glycomed Incorporated Highly sulfated maltooligosaccharides with heparin-like properties

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AUPO556297A0 (en) 1997-03-11 1997-04-10 Australian National University, The Sulfated oligosaccharides having anticoagulant/ antithrombotic activity
IL126893A (en) * 1997-11-19 2003-05-29 Akzo Nobel Nv Sulfated pentasaccharide derivatives and pharmaceutical compositions containing them
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RU2392281C2 (ru) * 2004-03-04 2010-06-20 Проджен Фармасьютикалз Лимитед Сульфатированные производные олигосахаридов

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO1996009828A1 (en) * 1994-09-26 1996-04-04 Glycomed Incorporated Highly sulfated maltooligosaccharides with heparin-like properties

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US7875592B2 (en) 2011-01-25
BRPI0508144A (pt) 2007-07-24
WO2005085264A1 (en) 2005-09-15
AU2005219456B2 (en) 2011-04-07
CA2557989C (en) 2013-04-23
HK1199263A1 (en) 2015-06-26
US20110130354A1 (en) 2011-06-02
EP1720889B1 (en) 2014-11-26
CN103788141A (zh) 2014-05-14
NO338461B1 (no) 2016-08-15
TW200602351A (en) 2006-01-16
AU2005219456A1 (en) 2005-09-15
CN104119404A (zh) 2014-10-29
CN1989146A (zh) 2007-06-27
IL177870A (en) 2011-08-31
ZA200607057B (en) 2008-04-30
MXPA06010049A (es) 2007-04-10
JP5139797B2 (ja) 2013-02-06
RU2006134972A (ru) 2008-04-10
US20070185037A1 (en) 2007-08-09
NO20064489L (no) 2006-11-27
US8173606B2 (en) 2012-05-08
CN103788141B (zh) 2016-08-17
CA2557989A1 (en) 2005-09-15
EP1720889A4 (en) 2008-03-19
EP1720889A1 (en) 2006-11-15
TWI426080B (zh) 2014-02-11
IL177870A0 (en) 2006-12-31
ES2531880T3 (es) 2015-03-20
RU2392281C2 (ru) 2010-06-20
JP2007526257A (ja) 2007-09-13
KR20070007815A (ko) 2007-01-16

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