ZA200601386B - Use of RNAI inhibiting PARP activity for the manufacture of a medicament for the treatment of cancer - Google Patents
Use of RNAI inhibiting PARP activity for the manufacture of a medicament for the treatment of cancer Download PDFInfo
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- ZA200601386B ZA200601386B ZA200601386A ZA200601386A ZA200601386B ZA 200601386 B ZA200601386 B ZA 200601386B ZA 200601386 A ZA200601386 A ZA 200601386A ZA 200601386 A ZA200601386 A ZA 200601386A ZA 200601386 B ZA200601386 B ZA 200601386B
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- parp
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- C12Y204/02—Pentosyltransferases (2.4.2)
- C12Y204/0203—NAD+ ADP-ribosyltransferase (2.4.2.30), i.e. tankyrase or poly(ADP-ribose) polymerase
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GBGB0317466.1A GB0317466D0 (en) | 2003-07-25 | 2003-07-25 | Use |
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ZA200601386A ZA200601386B (en) | 2003-07-25 | 2006-02-16 | Use of RNAI inhibiting PARP activity for the manufacture of a medicament for the treatment of cancer |
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US (5) | US8859562B2 (pt) |
EP (1) | EP1649017B2 (pt) |
JP (3) | JP5519097B2 (pt) |
KR (1) | KR101136702B1 (pt) |
CN (3) | CN1856572B (pt) |
AT (1) | ATE516353T1 (pt) |
AU (1) | AU2004261779B2 (pt) |
BR (1) | BRPI0412909B1 (pt) |
CA (1) | CA2533423C (pt) |
DK (1) | DK1649017T4 (pt) |
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GB (2) | GB0317466D0 (pt) |
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NO (1) | NO338398B1 (pt) |
NZ (1) | NZ545307A (pt) |
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PT (1) | PT1649017E (pt) |
WO (1) | WO2005012524A1 (pt) |
ZA (1) | ZA200601386B (pt) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
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US6956035B2 (en) | 2001-08-31 | 2005-10-18 | Inotek Pharmaceuticals Corporation | Isoquinoline derivatives and methods of use thereof |
BRPI0407757A (pt) | 2003-02-28 | 2006-02-14 | Inotek Pharmaceuticals Corp | derivados de benzamida tetracìclica e métodos de uso dos mesmos |
DK1660095T3 (da) | 2003-07-25 | 2010-05-25 | Cancer Rec Tech Ltd | Tricykliske PARP-inhibitorer |
GB0317466D0 (en) * | 2003-07-25 | 2003-08-27 | Univ Sheffield | Use |
NZ547984A (en) * | 2003-12-01 | 2009-03-31 | Kudos Pharm Ltd | DNA damage repair inhibitors for treatment of cancer |
CA2594234A1 (en) * | 2005-01-07 | 2006-07-27 | Arqule, Inc. | Compositions for modulation of parp and methods for screening for same |
WO2006078711A2 (en) | 2005-01-19 | 2006-07-27 | Mgi Gp, Inc. | Diazabenzo[de]anthracen-3-one compounds and methods for inhibiting parp |
CA2598647A1 (en) | 2005-02-25 | 2006-09-08 | Inotek Pharmaceuticals Corporation | Tetracyclic amino and carboxamido compounds and methods of use thereof |
BRPI0615096A2 (pt) | 2005-08-24 | 2009-07-14 | Inotek Pharmaceuticals Corp | análogos de indenoisoquinolinona e métodos de uso dos mesmos |
ES2361566T3 (es) * | 2005-11-25 | 2011-06-20 | Pharma Mar S.A., Sociedad Unipersonal | Uso de inhibidores de parp-1. |
WO2008066624A2 (en) * | 2006-10-20 | 2008-06-05 | Dana-Farber Cancer Institute | Dna damage repair inhibitors and methods for treating cancer |
AU2007340129B2 (en) * | 2006-12-26 | 2012-02-02 | Pharmacyclics Llc | Method of using histone deacetylase inhibitors and monitoring biomarkers in combination therapy |
MX2009009183A (es) | 2007-02-28 | 2009-09-07 | Inotek Pharmaceuticals Corp | Analogos de indenoisoquinolinona y metodos de utilizacion de los mismos. |
GB0707556D0 (en) * | 2007-04-19 | 2007-05-30 | Isis Innovation | Treatment for cancer |
JP5335673B2 (ja) | 2007-06-20 | 2013-11-06 | 学校法人 埼玉医科大学 | 子宮癌、乳癌、及び膀胱癌の予防乃至治療に好適な二本鎖核酸分子、癌細胞増殖抑制剤、並びに医薬 |
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