ZA200509549B - Pharmaceutical composition in the form of a hydrogel for transdermal administration of active substances - Google Patents

Pharmaceutical composition in the form of a hydrogel for transdermal administration of active substances Download PDF

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Publication number
ZA200509549B
ZA200509549B ZA200509549A ZA200509549A ZA200509549B ZA 200509549 B ZA200509549 B ZA 200509549B ZA 200509549 A ZA200509549 A ZA 200509549A ZA 200509549 A ZA200509549 A ZA 200509549A ZA 200509549 B ZA200509549 B ZA 200509549B
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ZA
South Africa
Prior art keywords
weight
composition according
composition
alkyl
active ingredient
Prior art date
Application number
ZA200509549A
Other languages
English (en)
Inventor
Franke Patrick
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33395772&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200509549(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA200509549B publication Critical patent/ZA200509549B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06Anabolic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26Androgens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
ZA200509549A 2003-04-28 2005-11-24 Pharmaceutical composition in the form of a hydrogel for transdermal administration of active substances ZA200509549B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03008856 2003-04-28

Publications (1)

Publication Number Publication Date
ZA200509549B true ZA200509549B (en) 2007-02-28

Family

ID=33395772

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200509549A ZA200509549B (en) 2003-04-28 2005-11-24 Pharmaceutical composition in the form of a hydrogel for transdermal administration of active substances

Country Status (33)

Country Link
EP (2) EP1875905B1 (no)
JP (2) JP4829102B2 (no)
KR (1) KR101093999B1 (no)
CN (1) CN1780610B (no)
AR (1) AR044113A1 (no)
AT (2) ATE385786T1 (no)
AU (1) AU2004233572B2 (no)
BR (1) BRPI0409918A (no)
CA (1) CA2523734C (no)
CL (1) CL2004000884A1 (no)
CO (1) CO5640075A2 (no)
CR (1) CR8059A (no)
CY (1) CY1108069T1 (no)
DE (2) DE502004011164D1 (no)
DK (1) DK1617827T3 (no)
EA (1) EA008686B1 (no)
EC (1) ECSP056186A (no)
ES (2) ES2345458T3 (no)
HK (1) HK1087633A1 (no)
HR (1) HRP20080178T3 (no)
JO (1) JO2492B1 (no)
MX (1) MXPA05011541A (no)
NO (1) NO20055601L (no)
NZ (2) NZ583760A (no)
PE (1) PE20050461A1 (no)
PL (1) PL1617827T3 (no)
PT (1) PT1617827E (no)
RS (1) RS51307B (no)
SI (1) SI1617827T1 (no)
TW (1) TWI343259B (no)
UA (1) UA83036C2 (no)
WO (1) WO2004096191A1 (no)
ZA (1) ZA200509549B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0506141D0 (en) * 2005-03-24 2005-05-04 Transphase Ltd A topical compostion and its uses
GB0506139D0 (en) * 2005-03-24 2005-05-04 Transphase Ltd A transdermal topical composition and its uses
DE102005015128B4 (de) * 2005-03-31 2008-12-11 Bayer Schering Pharma Aktiengesellschaft Wafer enthaltend Steroidhormone
DE102005035879A1 (de) * 2005-07-30 2007-02-01 Paul Hartmann Ag Hydrogel
SE536091C2 (sv) * 2011-04-14 2013-04-30 Pep Tonic Medical Ab Farmaceutisk komposition innehållande oxytocin eller fragment eller varianter därav och åtminstone en icke-jonisk cellulosaeter
PT2702982T (pt) * 2011-04-25 2017-03-17 Park Jun-Hyoung Composição para aplicação tópica para a prevenção da perda de cabelo e estimulação do crescimento capilar
FR2976808B1 (fr) * 2011-06-22 2013-06-28 Urgo Lab Composition filmogene et son utilisation pour le traitement de l'herpes
US9855211B2 (en) * 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
DE102018213754A1 (de) * 2018-08-15 2020-02-20 Henkel Ag & Co. Kgaa "Tris(hydroxymethyl-)aminomethan oder seine Salze als Wirkstoff zur Reduzierung der Schweißsekretion“

Family Cites Families (32)

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Publication number Priority date Publication date Assignee Title
DE1182229B (de) 1960-11-16 1964-11-26 Upjohn Co Verfahren zur Herstellung von 7-Methylsteroiden
US3341557A (en) 1961-06-05 1967-09-12 Upjohn Co 7-methyltestosterones
US3924004A (en) 1971-11-24 1975-12-02 Syntex Corp Fatty alcohol-propylene carbonate-glycol solvent cream vehicle
US4000273A (en) 1973-11-01 1976-12-28 Richardson-Merrell Inc. Method for the control of fertility
JPS5540604A (en) * 1978-09-14 1980-03-22 Mitsui Toatsu Chem Inc Improved local topicum
FR2518879A1 (fr) * 1981-12-30 1983-07-01 Besins Jean Medicament a base d'oestradiol pour le traitement de la pathologie menopausique
JPS5970612A (ja) * 1982-10-13 1984-04-21 Nippon Redarii Kk ゲル軟膏基剤
EP0319555B1 (de) * 1987-05-27 1992-01-29 Kurt Dr. Burghart Transdermal therapeutisch wirkende pharmazeutische zubereitung sowie vorrichtung zum aufbringen der zubereitung
ES2081823T3 (es) * 1988-10-27 1996-03-16 Schering Ag Agente para la aplicacion transdermica, que contiene gestoden.
KR950701508A (ko) * 1992-06-11 1995-04-28 챨스 디 에버트 경피식 약물수송을 조절하기 위한 글리세린의 용도(the use of glycerin in moderating transdermal drug delivery)
US5460620A (en) * 1992-07-31 1995-10-24 Creative Products Resource, Inc. Method of applying in-tandem applicator pads for transdermal delivery of a therapeutic agent
WO1996008255A1 (en) 1994-09-14 1996-03-21 Minnesota Mining And Manufacturing Company Transdermal device for delivery of levonorgestrel
FR2732223B1 (fr) 1995-03-30 1997-06-13 Sanofi Sa Composition pharmaceutique pour administration transdermique
DE19526864A1 (de) 1995-07-22 1997-01-23 Labtec Gmbh Hormonpflaster
JPH09194396A (ja) 1996-01-17 1997-07-29 Pola Chem Ind Inc 貼付剤用マトリックス
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KR970064620A (ko) * 1996-03-05 1997-10-13 임성기 사이클로스포린-함유 외용약제 조성물
US5736128A (en) * 1996-05-14 1998-04-07 Isp Investments Inc. Cosmetic composition for rejuvenation of skin without skin irritation
JP2000513336A (ja) 1996-05-22 2000-10-10 ディバーシファイド ファーマシューティカルズ,インコーポレーテッド 薬物の経皮送達のための組成物、方法及びデバイス
IT1283102B1 (it) * 1996-06-06 1998-04-07 Permatec Nv Composizione terapeutica per la somministrazione transdermica di un principio attivo estrogeno o progestinico o di loro miscele
US5993787A (en) 1996-09-13 1999-11-30 Johnson & Johnson Consumer Products, Inc. Composition base for topical therapeutic and cosmetic preparations
US20020012694A1 (en) 1997-09-17 2002-01-31 Alfred J. Moo-Young Transdermal administration of ment
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EP1087986B1 (en) 1998-06-19 2002-04-10 Akzo Nobel N.V. 7.alpha.-methyl 19-nortestosterone undecanoate with androgenic activity
FR2781666B1 (fr) * 1998-07-30 2000-09-08 Oreal Composition cosmetique solide et ses utilisations
JP2935113B1 (ja) * 1998-09-24 1999-08-16 小林製薬株式会社 インドメタシン経皮吸収剤
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JP2000264899A (ja) * 1999-01-13 2000-09-26 Taisho Pharmaceut Co Ltd ステロイド外用剤
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DE10107663B4 (de) 2001-02-19 2004-09-09 Lts Lohmann Therapie-Systeme Ag Testosteronhaltiges transdermales therapeutisches System, Verfahren zu seiner Herstellung und seine Verwendung

Also Published As

Publication number Publication date
KR20060007403A (ko) 2006-01-24
EA008686B1 (ru) 2007-06-29
DE502004011164D1 (de) 2010-06-24
EP1875905A2 (de) 2008-01-09
SI1617827T1 (sl) 2008-06-30
KR101093999B1 (ko) 2011-12-15
HRP20080178T3 (en) 2008-05-31
UA83036C2 (ru) 2008-06-10
ATE467412T1 (de) 2010-05-15
RS20050809A (en) 2007-09-21
CY1108069T1 (el) 2014-02-12
JP2006524653A (ja) 2006-11-02
PE20050461A1 (es) 2005-08-13
AU2004233572B2 (en) 2010-07-15
ATE385786T1 (de) 2008-03-15
NZ583760A (en) 2011-10-28
EP1875905A3 (de) 2008-06-25
ECSP056186A (es) 2006-04-19
EP1617827A1 (de) 2006-01-25
PL1617827T3 (pl) 2008-07-31
ES2300763T3 (es) 2008-06-16
AR044113A1 (es) 2005-08-24
DK1617827T3 (da) 2008-06-02
NZ543264A (en) 2010-03-26
CO5640075A2 (es) 2006-05-31
AU2004233572A1 (en) 2004-11-11
JP2010241824A (ja) 2010-10-28
CR8059A (es) 2006-05-29
NO20055601D0 (no) 2005-11-25
BRPI0409918A (pt) 2006-04-25
CL2004000884A1 (es) 2005-03-11
RS51307B (sr) 2010-12-31
PT1617827E (pt) 2008-04-30
CA2523734A1 (en) 2004-11-11
MXPA05011541A (es) 2006-05-31
JO2492B1 (en) 2009-10-05
WO2004096191A1 (de) 2004-11-11
HK1087633A1 (en) 2006-10-20
NO20055601L (no) 2006-01-26
EA200501583A1 (ru) 2006-06-30
TW200524644A (en) 2005-08-01
CN1780610A (zh) 2006-05-31
CA2523734C (en) 2009-12-22
EP1875905B1 (de) 2010-05-12
TWI343259B (en) 2011-06-11
JP4829102B2 (ja) 2011-12-07
EP1617827B1 (de) 2008-02-13
CN1780610B (zh) 2010-06-09
ES2345458T3 (es) 2010-09-23
DE502004006196D1 (de) 2008-03-27

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