JPS5540604A - Improved local topicum - Google Patents
Improved local topicumInfo
- Publication number
- JPS5540604A JPS5540604A JP11227278A JP11227278A JPS5540604A JP S5540604 A JPS5540604 A JP S5540604A JP 11227278 A JP11227278 A JP 11227278A JP 11227278 A JP11227278 A JP 11227278A JP S5540604 A JPS5540604 A JP S5540604A
- Authority
- JP
- Japan
- Prior art keywords
- topicum
- polymeric compound
- hpc
- active component
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To prepare a local topicum gel suppressing bleeding of the polymeric compound on the surface of the skin, thereby giving improved feeling in use, and containing a specific cellulosic polymeric compound.
CONSTITUTION: A topicum containing a cellulosic polymeric compound soluble in water and alcohols, preferably hydroxypropylcellulose (HPC). HPC is registered in the Japan PHarmacopoeia and prepared by reacting cellulose with propylene oxide. A topicum containing about 1W5wt% of HPC can suppress the bleeding. The specific cellulosic polymeric compound is particularly useful for topicums comprising a carboxyvinyl polymer as a base. In compounding the gel for an aqueous topicum with an active component poorly soluble in water, addition of propylene carbonate is effective to improve the solubility of the active component.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11227278A JPS5540604A (en) | 1978-09-14 | 1978-09-14 | Improved local topicum |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP11227278A JPS5540604A (en) | 1978-09-14 | 1978-09-14 | Improved local topicum |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5540604A true JPS5540604A (en) | 1980-03-22 |
JPS6218526B2 JPS6218526B2 (en) | 1987-04-23 |
Family
ID=14582543
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP11227278A Granted JPS5540604A (en) | 1978-09-14 | 1978-09-14 | Improved local topicum |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5540604A (en) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5750914A (en) * | 1980-09-12 | 1982-03-25 | Shionogi & Co Ltd | Betamethasone external pharmaceutical |
EP0101178A2 (en) | 1982-07-13 | 1984-02-22 | Pfizer Corporation | Topical anti-inflammatory compositions |
JPS6168413A (en) * | 1984-09-10 | 1986-04-08 | Lion Corp | Gel composition for external use |
JPS61257920A (en) * | 1985-05-13 | 1986-11-15 | Sato Seiyaku Kk | Antimycotic gelatinous agent for external use |
JPS6251617A (en) * | 1985-08-30 | 1987-03-06 | Wako Pure Chem Ind Ltd | Vidarabin gel ointment |
JPS6251619A (en) * | 1985-08-30 | 1987-03-06 | Wako Pure Chem Ind Ltd | Gel pharmaceutical for external use |
US4664909A (en) * | 1980-12-29 | 1987-05-12 | Colgate-Palmolive Company | Stable suspension of powder in alcoholic media |
WO1989010745A1 (en) * | 1988-05-02 | 1989-11-16 | Pomerantz, Edwin | Compositions and in situ methods for forming films on body tissue |
US5840809A (en) * | 1995-07-03 | 1998-11-24 | Daicel Chemical Industries, Ltd. | Epoxidized block copolymer, its production, and its composition |
JP2010241824A (en) * | 2003-04-28 | 2010-10-28 | Bayer Schering Pharma Ag | Pharmaceutical composition in the form of hydrogel for transdermal administration of active substance |
-
1978
- 1978-09-14 JP JP11227278A patent/JPS5540604A/en active Granted
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5750914A (en) * | 1980-09-12 | 1982-03-25 | Shionogi & Co Ltd | Betamethasone external pharmaceutical |
JPH0231052B2 (en) * | 1980-09-12 | 1990-07-11 | Shionogi & Co | |
US4664909A (en) * | 1980-12-29 | 1987-05-12 | Colgate-Palmolive Company | Stable suspension of powder in alcoholic media |
EP0101178A2 (en) | 1982-07-13 | 1984-02-22 | Pfizer Corporation | Topical anti-inflammatory compositions |
JPS6168413A (en) * | 1984-09-10 | 1986-04-08 | Lion Corp | Gel composition for external use |
JPS61257920A (en) * | 1985-05-13 | 1986-11-15 | Sato Seiyaku Kk | Antimycotic gelatinous agent for external use |
JPH0226603B2 (en) * | 1985-05-13 | 1990-06-12 | Sato Pharma | |
JPS6251617A (en) * | 1985-08-30 | 1987-03-06 | Wako Pure Chem Ind Ltd | Vidarabin gel ointment |
JPS6251619A (en) * | 1985-08-30 | 1987-03-06 | Wako Pure Chem Ind Ltd | Gel pharmaceutical for external use |
WO1989010745A1 (en) * | 1988-05-02 | 1989-11-16 | Pomerantz, Edwin | Compositions and in situ methods for forming films on body tissue |
US5840809A (en) * | 1995-07-03 | 1998-11-24 | Daicel Chemical Industries, Ltd. | Epoxidized block copolymer, its production, and its composition |
JP2010241824A (en) * | 2003-04-28 | 2010-10-28 | Bayer Schering Pharma Ag | Pharmaceutical composition in the form of hydrogel for transdermal administration of active substance |
JP4829102B2 (en) * | 2003-04-28 | 2011-12-07 | バイエル ファーマ アクチエンゲゼルシャフト | Pharmaceutical composition in the form of a hydrogel for transdermal administration of the active ingredient |
Also Published As
Publication number | Publication date |
---|---|
JPS6218526B2 (en) | 1987-04-23 |
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