ZA200507067B - Antibodies against human IL-21 receptor and uses therefor - Google Patents
Antibodies against human IL-21 receptor and uses thereforInfo
- Publication number
- ZA200507067B ZA200507067B ZA200507067A ZA200507067A ZA200507067B ZA 200507067 B ZA200507067 B ZA 200507067B ZA 200507067 A ZA200507067 A ZA 200507067A ZA 200507067 A ZA200507067 A ZA 200507067A ZA 200507067 B ZA200507067 B ZA 200507067B
- Authority
- ZA
- South Africa
- Prior art keywords
- receptor
- antibodies against
- against human
- uses therefor
- therefor
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45433603P | 2003-03-14 | 2003-03-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200507067B true ZA200507067B (en) | 2006-12-27 |
Family
ID=33029874
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200507067A ZA200507067B (en) | 2003-03-14 | 2005-09-02 | Antibodies against human IL-21 receptor and uses therefor |
Country Status (20)
Country | Link |
---|---|
US (2) | US7495085B2 (es) |
EP (2) | EP2184298A1 (es) |
JP (1) | JP4914209B2 (es) |
KR (1) | KR20050119120A (es) |
CN (2) | CN1777621A (es) |
AR (1) | AR043616A1 (es) |
AT (1) | ATE456581T1 (es) |
AU (1) | AU2004221876B2 (es) |
BR (1) | BRPI0408315A (es) |
CA (1) | CA2518371A1 (es) |
CL (1) | CL2004000534A1 (es) |
CO (1) | CO5660297A2 (es) |
DE (1) | DE602004025332D1 (es) |
ES (1) | ES2340280T3 (es) |
MX (1) | MXPA05009556A (es) |
NO (1) | NO20054170L (es) |
NZ (1) | NZ542306A (es) |
RU (1) | RU2005131852A (es) |
WO (1) | WO2004083249A2 (es) |
ZA (1) | ZA200507067B (es) |
Families Citing this family (41)
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ZA200507235B (en) * | 2003-03-21 | 2007-03-28 | Wyeth Corp | Treating immunological disorders using agonists of interleukin-21/interleukin-21 receptor |
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KR20070057789A (ko) * | 2004-08-05 | 2007-06-07 | 와이어쓰 | 인터루킨-21 수용체 활성의 상쇄 |
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DK1963369T3 (da) | 2005-11-28 | 2013-06-03 | Zymogenetics Inc | Il-21-antagonister |
CA2632218A1 (en) * | 2005-11-28 | 2007-10-11 | Zymogenetics, Inc. | Il-21 receptor antagonists |
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CA2633157C (en) | 2005-12-09 | 2018-10-09 | Academisch Medisch Centrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of antibody producing cells |
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EP1787997A1 (en) * | 2000-05-11 | 2007-05-23 | Genetics Institute, LLC | MU-1, member of the cytokine receptor family |
CA2407910C (en) * | 2000-06-16 | 2013-03-12 | Steven M. Ruben | Antibodies that immunospecifically bind to blys |
DK1432431T3 (en) | 2001-10-04 | 2017-07-10 | Genetics Inst Llc | Methods and compositions for modulating interleukin-21 activity |
WO2003040313A2 (en) | 2001-11-05 | 2003-05-15 | Zymogenetics, Inc | Il-21 antagonists |
US20040016010A1 (en) | 2002-04-17 | 2004-01-22 | Marion Kasaian | IL-21 receptor knockout animal and methods of use thereof |
WO2004007682A2 (en) | 2002-07-15 | 2004-01-22 | Wyeth | Methods and compositions for modulating t helper (th) cell development and function |
BRPI0408315A (pt) | 2003-03-14 | 2006-03-07 | Wyeth Corp | anticorpo isolado, composição farmacêutica, ácido nucleico isolado, vetor de expressão, célula hospedeira, métodos de produzir um anticorpo, de gerar um anticorpo ou fragmento de ligação de antìgeno, de regular uma resposta imune, de tratar ou prevenir um distúrbio associado com célula imune em um paciente, de tratar ou prevenir um distúrbio hiperproliferativo em um paciente, e, kit de diagnóstico |
ZA200507235B (en) | 2003-03-21 | 2007-03-28 | Wyeth Corp | Treating immunological disorders using agonists of interleukin-21/interleukin-21 receptor |
JP2008501042A (ja) | 2004-05-19 | 2008-01-17 | ワイス | 免疫グロブリン産生の調節とアトピー性疾患 |
KR20070057789A (ko) | 2004-08-05 | 2007-06-07 | 와이어쓰 | 인터루킨-21 수용체 활성의 상쇄 |
GT200600148A (es) | 2005-04-14 | 2006-11-22 | Metodos para el tratamiento y la prevencion de fibrosis | |
WO2009100035A2 (en) | 2008-02-01 | 2009-08-13 | Wyeth | Interleukin-21 (il-21) and il-21 receptor (il-21r) modulation of regulatory t cells and forkhead box p3 (foxp3) |
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2004
- 2004-03-12 BR BRPI0408315-6A patent/BRPI0408315A/pt not_active IP Right Cessation
- 2004-03-12 RU RU2005131852/13A patent/RU2005131852A/ru not_active Application Discontinuation
- 2004-03-12 JP JP2006507081A patent/JP4914209B2/ja not_active Expired - Fee Related
- 2004-03-12 CN CNA2004800105188A patent/CN1777621A/zh active Pending
- 2004-03-12 US US10/798,380 patent/US7495085B2/en not_active Expired - Fee Related
- 2004-03-12 AU AU2004221876A patent/AU2004221876B2/en not_active Ceased
- 2004-03-12 WO PCT/US2004/007444 patent/WO2004083249A2/en active Application Filing
- 2004-03-12 EP EP09178337A patent/EP2184298A1/en not_active Withdrawn
- 2004-03-12 CA CA002518371A patent/CA2518371A1/en not_active Abandoned
- 2004-03-12 ES ES04720349T patent/ES2340280T3/es not_active Expired - Lifetime
- 2004-03-12 NZ NZ542306A patent/NZ542306A/en unknown
- 2004-03-12 MX MXPA05009556A patent/MXPA05009556A/es active IP Right Grant
- 2004-03-12 DE DE602004025332T patent/DE602004025332D1/de not_active Expired - Lifetime
- 2004-03-12 AT AT04720349T patent/ATE456581T1/de not_active IP Right Cessation
- 2004-03-12 KR KR1020057017254A patent/KR20050119120A/ko not_active Application Discontinuation
- 2004-03-12 EP EP04720349A patent/EP1603949B9/en not_active Revoked
- 2004-03-12 CN CN2010101657309A patent/CN102040662A/zh active Pending
- 2004-03-15 AR ARP040100859A patent/AR043616A1/es unknown
- 2004-03-15 CL CL200400534A patent/CL2004000534A1/es unknown
-
2005
- 2005-09-02 ZA ZA200507067A patent/ZA200507067B/xx unknown
- 2005-09-07 NO NO20054170A patent/NO20054170L/no not_active Application Discontinuation
- 2005-09-14 CO CO05093185A patent/CO5660297A2/es not_active Application Discontinuation
-
2009
- 2009-01-14 US US12/353,812 patent/US8143385B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2007525159A (ja) | 2007-09-06 |
US7495085B2 (en) | 2009-02-24 |
BRPI0408315A (pt) | 2006-03-07 |
EP1603949A2 (en) | 2005-12-14 |
AU2004221876B2 (en) | 2011-05-26 |
CN102040662A (zh) | 2011-05-04 |
EP1603949B9 (en) | 2011-02-02 |
AU2004221876A1 (en) | 2004-09-30 |
KR20050119120A (ko) | 2005-12-20 |
CN1777621A (zh) | 2006-05-24 |
ES2340280T3 (es) | 2010-06-01 |
NO20054170L (no) | 2005-12-05 |
ATE456581T1 (de) | 2010-02-15 |
WO2004083249A2 (en) | 2004-09-30 |
MXPA05009556A (es) | 2005-11-16 |
DE602004025332D1 (de) | 2010-03-18 |
EP2184298A1 (en) | 2010-05-12 |
WO2004083249A3 (en) | 2004-12-09 |
US8143385B2 (en) | 2012-03-27 |
US20040265960A1 (en) | 2004-12-30 |
EP1603949B8 (en) | 2010-03-10 |
CO5660297A2 (es) | 2006-07-31 |
JP4914209B2 (ja) | 2012-04-11 |
AR043616A1 (es) | 2005-08-03 |
RU2005131852A (ru) | 2006-04-20 |
CL2004000534A1 (es) | 2005-03-04 |
NZ542306A (en) | 2008-04-30 |
NO20054170D0 (no) | 2005-09-07 |
CA2518371A1 (en) | 2004-09-30 |
EP1603949B1 (en) | 2010-01-27 |
US20100297151A1 (en) | 2010-11-25 |
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