DK3099709T3 - Midler og fremgangsmåder til fremstilling af stabile antistoffer - Google Patents
Midler og fremgangsmåder til fremstilling af stabile antistoffer Download PDFInfo
- Publication number
- DK3099709T3 DK3099709T3 DK15704857.0T DK15704857T DK3099709T3 DK 3099709 T3 DK3099709 T3 DK 3099709T3 DK 15704857 T DK15704857 T DK 15704857T DK 3099709 T3 DK3099709 T3 DK 3099709T3
- Authority
- DK
- Denmark
- Prior art keywords
- procedures
- manufacture
- methods
- stable antibodies
- antibodies
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1018—Orthomyxoviridae, e.g. influenza virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14153480 | 2014-01-31 | ||
| PCT/NL2015/050054 WO2015115892A1 (en) | 2014-01-31 | 2015-01-30 | Means and methods for producing stable antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3099709T3 true DK3099709T3 (da) | 2020-02-03 |
Family
ID=50031190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15704857.0T DK3099709T3 (da) | 2014-01-31 | 2015-01-30 | Midler og fremgangsmåder til fremstilling af stabile antistoffer |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10611829B2 (da) |
| EP (1) | EP3099709B1 (da) |
| JP (1) | JP6747975B2 (da) |
| AU (1) | AU2015211480B2 (da) |
| CA (1) | CA2938193C (da) |
| DK (1) | DK3099709T3 (da) |
| WO (1) | WO2015115892A1 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2927905T3 (es) * | 2013-12-24 | 2022-11-11 | Kling Biotherapeutics B V | Producción de anticuerpos ex vivo |
| KR102037183B1 (ko) * | 2018-02-09 | 2019-10-28 | 엠랩 주식회사 | 스트리밍 미디어에 코멘트를 맵핑하는 시스템 및 방법 |
Family Cites Families (48)
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| US4997764A (en) | 1987-04-23 | 1991-03-05 | New York University | Transformation of human B-lympocytes with Epstein Barr virus and c-myc containing vectors |
| JPH04501052A (ja) | 1988-02-26 | 1992-02-27 | ザ・ウスター・フアウンデーシヨン・フオー・バイオメデイカル・リサーチ | 外来性オリゴヌクレオチドによるｈｔｌｖ―３の抑制 |
| US5866757A (en) | 1992-06-02 | 1999-02-02 | Yeda Research And Development Co. Ltd. | Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems |
| WO1994007367A1 (en) | 1992-09-29 | 1994-04-14 | Apollon, Inc. | Anti-viral oligomers that bind polypurine tracts of single-stranded rna or rna-dna hybrids |
| ATE146819T1 (de) | 1992-10-05 | 1997-01-15 | Hybridon Inc | Therapeutisches anti-hiv oligonukleotid und arzneimittel |
| WO1994017086A1 (en) | 1993-01-25 | 1994-08-04 | Apollon, Inc. | Gene regulation by targeting putative intramolecular triple helix |
| US5550019A (en) | 1993-05-26 | 1996-08-27 | La Jolla Cancer Research Foundation | Methods of identifying compounds which alter apoptosis |
| US5866755A (en) | 1993-06-14 | 1999-02-02 | Basf Aktiengellschaft | Animals transgenic for a tetracycline-regulated transcriptional inhibitor |
| WO1995006409A1 (en) | 1993-09-03 | 1995-03-09 | Systemix, Inc. | Genetically modified human hematopoietic stem cells and their progeny |
| GB9425060D0 (en) | 1994-12-13 | 1995-02-08 | Univ Birmingham | Carcinoma treatment |
| US6001558A (en) | 1997-06-25 | 1999-12-14 | Ortho Clinical Diagnostics, Inc. | Amplification and detection of HIV-1 and/or HIV 2 |
| JP2003509025A (ja) | 1999-09-08 | 2003-03-11 | ジーントロール バイオセラピューティクス， インコーポレイテッド | 細胞生存能力が増強した高レベルサイトカイン産生 |
| EP1083230A1 (en) | 1999-09-10 | 2001-03-14 | Academisch Medisch Centrum Amsterdam | Viral replicons and viruses dependent on inducing agents |
| US7122180B2 (en) | 2000-10-23 | 2006-10-17 | Children's Medical Center Corporation | DNA vectors containing mutated HIV proviruses |
| US20030175950A1 (en) | 2001-05-29 | 2003-09-18 | Mcswiggen James A. | RNA interference mediated inhibition of HIV gene expression using short interfering RNA |
| JP2003012698A (ja) * | 2001-06-26 | 2003-01-15 | Toyota Central Res & Dev Lab Inc | モノクローナル抗体 |
| US20050009180A1 (en) | 2001-12-10 | 2005-01-13 | Lili Yang | Method for the generation of antigen-specific lymphocytes |
| US20030152559A1 (en) | 2001-12-10 | 2003-08-14 | Lili Yang | Method for the generation of antigen-specific lymphocytes |
| SI1458855T1 (sl) | 2001-12-18 | 2012-08-31 | Cancer Rec Tech Ltd | Postopek za pripravo proliferacijskih in diferenciacijskih celičnih linij |
| CA2471392A1 (en) | 2001-12-22 | 2003-08-21 | 4-Antibody Ag | Method for the generation of genetically modified vertebrate precursor lymphocytes and use thereof for the production of heterologous binding proteins |
| US20040248296A1 (en) | 2002-03-20 | 2004-12-09 | Beresford Paul J. | HIV therapeutic |
| GB2398783A (en) | 2003-02-26 | 2004-09-01 | Antonio Lanzavecchia | A method for producing immortalised human B memory lymphocytes |
| NZ542306A (en) | 2003-03-14 | 2008-04-30 | Wyeth Corp | Antibodies against human IL-21 receptor and uses therefor |
| WO2005044854A2 (en) | 2003-11-04 | 2005-05-19 | Chiron Corporation | Antagonist anti-cd40 monoclonal antibodies and methods for their use |
| DE602004028280D1 (de) | 2003-11-19 | 2010-09-02 | Us Gov Health & Human Serv | Verfahren zur induktion der entwicklung und terminalen differenzierung von gedächtnis-b-zellen |
| GB0327384D0 (en) | 2003-11-25 | 2003-12-31 | Queen Mary & Westfield College | Gene therapy |
| US20050238626A1 (en) | 2004-04-01 | 2005-10-27 | Lili Yang | Antigen specific T cell therapy |
| WO2005123923A2 (en) | 2004-06-17 | 2005-12-29 | Wolfgang Hillen | Inducer specific tetracycline repressor proteins and methods of use thereof |
| EP1627563A1 (en) | 2004-08-10 | 2006-02-22 | Academisch Medisch Centrum bij de Universiteit van Amsterdam | Means and methods for producing a stabilized cell of interest |
| EP1647595A1 (en) | 2004-10-15 | 2006-04-19 | Academisch Medisch Centrum bij de Universiteit van Amsterdam | Nucleic acids against viruses, in particular HIV |
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| FI1974017T4 (fi) | 2005-12-09 | 2023-09-14 | Välineitä ja menetelmiä, joilla voidaan vaikuttaa vasta-ainetta tuottavien solujen stabiliteettiin | |
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| CN102482639B (zh) | 2009-04-03 | 2016-01-06 | 医学研究会 | 活化诱导胞苷脱氨酶(aid)突变体及使用方法 |
| JP5781508B2 (ja) | 2009-07-15 | 2015-09-24 | アイム・セラピューティクス・べー・フェー | 高親和性抗体を産生させるための手段および方法 |
| HUE038277T2 (hu) | 2009-07-15 | 2018-10-29 | Aimm Therapeutics Bv | Gram-pozitív baktériumokra specifikus kötõvegyületek |
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| UY34887A (es) | 2012-07-02 | 2013-12-31 | Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware | Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos |
-
2015
- 2015-01-30 WO PCT/NL2015/050054 patent/WO2015115892A1/en active Application Filing
- 2015-01-30 EP EP15704857.0A patent/EP3099709B1/en active Active
- 2015-01-30 AU AU2015211480A patent/AU2015211480B2/en active Active
- 2015-01-30 JP JP2016549244A patent/JP6747975B2/ja active Active
- 2015-01-30 CA CA2938193A patent/CA2938193C/en active Active
- 2015-01-30 DK DK15704857.0T patent/DK3099709T3/da active
- 2015-01-30 US US15/113,563 patent/US10611829B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2015211480A1 (en) | 2016-08-11 |
| AU2015211480B2 (en) | 2020-05-14 |
| CA2938193C (en) | 2023-05-02 |
| NZ723331A (en) | 2021-08-27 |
| BR112016017597A2 (pt) | 2017-08-08 |
| US10611829B2 (en) | 2020-04-07 |
| JP6747975B2 (ja) | 2020-08-26 |
| EP3099709B1 (en) | 2019-12-25 |
| EP3099709A1 (en) | 2016-12-07 |
| JP2017504345A (ja) | 2017-02-09 |
| CA2938193A1 (en) | 2015-09-06 |
| US20170008952A1 (en) | 2017-01-12 |
| WO2015115892A1 (en) | 2015-08-06 |
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