ZA200409228B - New salts. - Google Patents
New salts. Download PDFInfo
- Publication number
- ZA200409228B ZA200409228B ZA200409228A ZA200409228A ZA200409228B ZA 200409228 B ZA200409228 B ZA 200409228B ZA 200409228 A ZA200409228 A ZA 200409228A ZA 200409228 A ZA200409228 A ZA 200409228A ZA 200409228 B ZA200409228 B ZA 200409228B
- Authority
- ZA
- South Africa
- Prior art keywords
- acid
- compound
- salt
- addition salt
- acid addition
- Prior art date
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- 150000003839 salts Chemical class 0.000 title claims description 129
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
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| SE0201661A SE0201661D0 (sv) | 2002-05-31 | 2002-05-31 | New salts |
Publications (1)
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|---|---|
| ZA200409228B true ZA200409228B (en) | 2005-05-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| ZA200409228A ZA200409228B (en) | 2002-05-31 | 2004-11-17 | New salts. |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US7273858B2 (xx) |
| EP (2) | EP1513806B1 (xx) |
| JP (1) | JP4541140B2 (xx) |
| KR (1) | KR20050009726A (xx) |
| CN (2) | CN1656067A (xx) |
| AR (1) | AR039937A1 (xx) |
| AT (1) | ATE425963T1 (xx) |
| AU (1) | AU2003232871B2 (xx) |
| BR (1) | BR0311365A (xx) |
| CA (1) | CA2487509A1 (xx) |
| CY (1) | CY1109085T1 (xx) |
| DE (1) | DE60326720D1 (xx) |
| DK (1) | DK1513806T3 (xx) |
| ES (1) | ES2322048T3 (xx) |
| HK (1) | HK1073102A1 (xx) |
| IL (1) | IL165295A0 (xx) |
| IS (1) | IS7598A (xx) |
| MX (1) | MXPA04011912A (xx) |
| MY (1) | MY133333A (xx) |
| NO (1) | NO329064B1 (xx) |
| NZ (2) | NZ536738A (xx) |
| PL (1) | PL373794A1 (xx) |
| PT (1) | PT1513806E (xx) |
| RU (2) | RU2345064C2 (xx) |
| SA (1) | SA03240440B1 (xx) |
| SE (1) | SE0201661D0 (xx) |
| SI (1) | SI1513806T1 (xx) |
| TW (2) | TWI313173B (xx) |
| UA (1) | UA81246C2 (xx) |
| WO (1) | WO2003101957A1 (xx) |
| ZA (1) | ZA200409228B (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
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| AR035216A1 (es) | 2000-12-01 | 2004-05-05 | Astrazeneca Ab | Derivados de acido mandelico ,derivados farmaceuticamente aceptables, uso de estos derivados para la fabricacion de medicamentos, metodos de tratamiento ,procesos para la preparacion de estos derivados, y compuestos intermediarios |
| AR034517A1 (es) | 2001-06-21 | 2004-02-25 | Astrazeneca Ab | Formulacion farmaceutica |
| SE0201661D0 (sv) * | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | New salts |
| SE0201659D0 (sv) | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | Modified release pharmaceutical formulation |
| US7781424B2 (en) * | 2003-05-27 | 2010-08-24 | Astrazeneca Ab | Modified release pharmaceutical formulation |
| EP1732932B1 (en) * | 2004-04-09 | 2012-03-21 | Hanmi Holdings Co., Ltd. | Crystalline clopidogrel naphthalenesulfonate or hydrate thereof, method for preparing same and pharmaceutical composition containing same |
| WO2005103059A1 (en) * | 2004-04-20 | 2005-11-03 | Sanofi-Aventis | Clopidogrel salt and polymorphic forms thereof |
| TW200827336A (en) * | 2006-12-06 | 2008-07-01 | Astrazeneca Ab | New crystalline forms |
| TW200900033A (en) * | 2007-06-21 | 2009-01-01 | Wen-Qing Li | Automatic brewing machine |
| US20090061000A1 (en) * | 2007-08-31 | 2009-03-05 | Astrazeneca Ab | Pharmaceutical formulation use 030 |
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| HU178398B (en) * | 1979-06-12 | 1982-04-28 | Gyogyszerkutato Intezet | Process for producing new agmatine derivatives of activity against haemagglutination |
| JPS57149217A (en) | 1981-03-11 | 1982-09-14 | Kaken Pharmaceut Co Ltd | Slow-releasing pharmaceutical preparation |
| HU192646B (en) * | 1984-12-21 | 1987-06-29 | Gyogyszerkutato Intezet | Process for preparing new n-alkyl-peptide aldehydes |
| ZA86746B (en) | 1985-02-04 | 1986-09-24 | Merrell Dow Pharma | Novel peptidase inhibitors |
| US5187157A (en) | 1987-06-05 | 1993-02-16 | Du Pont Merck Pharmaceutical Company | Peptide boronic acid inhibitors of trypsin-like proteases |
| US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| EP0362002B1 (en) | 1988-09-01 | 1995-07-26 | Merrell Dow Pharmaceuticals Inc. | HIV protease inhibitors |
| ZA897514B (en) | 1988-10-07 | 1990-06-27 | Merrell Dow Pharma | Novel peptidase inhibitors |
| IT1229491B (it) * | 1988-12-28 | 1991-09-03 | Roussel Maestretti S P A Ora R | Derivati della 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro impiego come sostanze medicinali |
| TW201303B (xx) * | 1990-07-05 | 1993-03-01 | Hoffmann La Roche | |
| CA2075154A1 (en) | 1991-08-06 | 1993-02-07 | Neelakantan Balasubramanian | Peptide aldehydes as antithrombotic agents |
| SE9102462D0 (sv) | 1991-08-28 | 1991-08-28 | Astra Ab | New isosteric peptides |
| US5169638A (en) | 1991-10-23 | 1992-12-08 | E. R. Squibb & Sons, Inc. | Buoyant controlled release powder formulation |
| CZ333492A3 (en) | 1991-11-12 | 1993-09-15 | Lilly Co Eli | Dipeptide of l-azetidine-2-carboxylic acids and l-argininaldehyde, process of its preparation and pharmaceutical preparation in which said dipeptide is comprised |
| SE9103612D0 (sv) | 1991-12-04 | 1991-12-04 | Astra Ab | New peptide derivatives |
| DE69314478T2 (de) | 1992-03-04 | 1999-02-11 | Gyogyszerkutato Intezet Kft., Budapest | Neuartige antikoagulierende peptidderivate und arzneimittel die solche enthalten so wie entsprechendes herstellungsverfahren |
| TW223629B (xx) * | 1992-03-06 | 1994-05-11 | Hoffmann La Roche | |
| SE9301912D0 (sv) | 1993-06-03 | 1993-06-03 | Ab Astra | Process for the production of aminoalkylguandines |
| SE9301916D0 (sv) * | 1993-06-03 | 1993-06-03 | Ab Astra | New peptides derivatives |
| US5780631A (en) * | 1993-06-03 | 1998-07-14 | Astra Aktiebolag | Starting materials in the synthesis of thrombin and kininogenase inhibitors |
| US6984627B1 (en) * | 1993-06-03 | 2006-01-10 | Astrazeneca Ab | Peptide derivatives |
| EP0648780A1 (en) | 1993-08-26 | 1995-04-19 | Bristol-Myers Squibb Company | Heterocyclic thrombin inhibitors |
| TW394760B (en) | 1993-09-07 | 2000-06-21 | Hoffmann La Roche | Novel Carboxamides, process for their preparation and pharmaceutical composition containing the same |
| AU1025795A (en) | 1994-01-27 | 1995-08-03 | Mitsubishi Chemical Corporation | Prolineamide derivatives |
| IL112795A (en) | 1994-03-04 | 2001-01-28 | Astrazeneca Ab | Derivatives of peptides as antithrombotic drugs, their preparation, and pharmaceutical preparations containing them |
| US5707966A (en) * | 1994-03-04 | 1998-01-13 | Eli Lilly And Company | Antithrombotic agents |
| US5705487A (en) * | 1994-03-04 | 1998-01-06 | Eli Lilly And Company | Antithrombotic agents |
| US5561146A (en) | 1994-06-10 | 1996-10-01 | Bristol-Myers Squibb Company | Modified guanidino and amidino thrombin inhibitors |
| DE4421052A1 (de) * | 1994-06-17 | 1995-12-21 | Basf Ag | Neue Thrombininhibitoren, ihre Herstellung und Verwendung |
| US5498724A (en) * | 1994-06-28 | 1996-03-12 | Aktiebolaget Astra | Pyrazoleamidine compounds |
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| CN1198839C (zh) | 1995-02-17 | 2005-04-27 | 艾伯特有限及两合公司 | 作为凝血酶抑制剂的新的二肽脒类 |
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| SE9601556D0 (sv) | 1996-04-24 | 1996-04-24 | Astra Ab | New pharmaceutical formulation of a thrombin inhibitor for parenteral use |
| SE9602263D0 (sv) * | 1996-06-07 | 1996-06-07 | Astra Ab | New amino acid derivatives |
| AU3496297A (en) * | 1996-06-25 | 1998-01-14 | Eli Lilly And Company | Anticoagulant agents |
| SE9602646D0 (sv) * | 1996-07-04 | 1996-07-04 | Astra Ab | Pharmaceutically-useful compounds |
| DE19632772A1 (de) * | 1996-08-14 | 1998-02-19 | Basf Ag | Neue Benzamidine |
| SE9603724D0 (sv) | 1996-10-11 | 1996-10-11 | Astra Ab | New pharmaceutical parenteral formulation of a thrombin inhibitor |
| AR013084A1 (es) * | 1997-06-19 | 2000-12-13 | Astrazeneca Ab | Derivados de amidino utiles como inhibidores de la trombina, composicion farmaceutica, utilizacion de dichos compuestos para la preparacion demedicamentos y proceso para la preparacion de los compuestos mencionados |
| IT1297461B1 (it) | 1997-10-29 | 1999-12-17 | Ciocca Maurizio | Preparazione di compresse a rilascio controllato a base di complessi tra carragenano e farmaci basici solubili |
| SE9704543D0 (sv) * | 1997-12-05 | 1997-12-05 | Astra Ab | New compounds |
| US6251430B1 (en) | 1998-02-04 | 2001-06-26 | Guohua Zhang | Water insoluble polymer based sustained release formulation |
| US6174913B1 (en) * | 1998-06-05 | 2001-01-16 | The University Of North Carolina At Chapel Hill | Naphtho- and dihydrobenzo-thiophene derivatives as cytotoxic antitumor agents |
| SE9802938D0 (sv) | 1998-09-01 | 1998-09-01 | Astra Ab | Improved stability for injection solutions |
| SE9802973D0 (sv) | 1998-09-03 | 1998-09-03 | Astra Ab | Immediate release tablet |
| SE9802974D0 (sv) | 1998-09-03 | 1998-09-03 | Astra Ab | New crystalline forms |
| PT1107791E (pt) | 1998-09-04 | 2007-07-06 | Scios Inc | Composições de hidrogel para a administração com libertação controlada de factores de crescimento |
| SE9804313D0 (sv) * | 1998-12-14 | 1998-12-14 | Astra Ab | New compounds |
| BR0007453A (pt) * | 1999-01-13 | 2001-10-30 | Astrazeneca Ab | Composto, formulação farmacêutica, uso de umcomposto, método de tratamento de uma condiçãoonde a inibição da trombina é requerida e,processo de preparação de um composto |
| SE9902550D0 (sv) | 1999-07-02 | 1999-07-02 | Astra Ab | New crystalline forms |
| SE0001803D0 (sv) | 2000-05-16 | 2000-05-16 | Astrazeneca Ab | New compounds i |
| WO2002014270A1 (en) | 2000-08-16 | 2002-02-21 | Astrazeneca Ab | New amidino derivatives and their use as thrombin inhibitors |
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| SE0102921D0 (sv) * | 2001-08-30 | 2001-08-30 | Astrazeneca Ab | Pharmaceutically useful compounds |
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| AR034517A1 (es) * | 2001-06-21 | 2004-02-25 | Astrazeneca Ab | Formulacion farmaceutica |
| US6811794B2 (en) * | 2001-12-20 | 2004-11-02 | Shire Laboratories, Inc. | Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles |
| SE0201658D0 (sv) * | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | Immediate release pharmaceutical formulation |
| SE0201661D0 (sv) * | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | New salts |
| SE0201659D0 (sv) * | 2002-05-31 | 2002-05-31 | Astrazeneca Ab | Modified release pharmaceutical formulation |
| US7781424B2 (en) * | 2003-05-27 | 2010-08-24 | Astrazeneca Ab | Modified release pharmaceutical formulation |
| SE0303220D0 (sv) * | 2003-11-28 | 2003-11-28 | Astrazeneca Ab | New process |
| GB0503672D0 (en) * | 2005-02-23 | 2005-03-30 | Astrazeneca Ab | New process |
| GB0510546D0 (en) * | 2005-05-24 | 2005-06-29 | Astrazeneca Ab | New process |
| TW200827336A (en) * | 2006-12-06 | 2008-07-01 | Astrazeneca Ab | New crystalline forms |
-
2002
- 2002-05-31 SE SE0201661A patent/SE0201661D0/xx unknown
-
2003
- 2003-05-27 AU AU2003232871A patent/AU2003232871B2/en not_active Ceased
- 2003-05-27 EP EP03728206A patent/EP1513806B1/en not_active Expired - Lifetime
- 2003-05-27 CA CA002487509A patent/CA2487509A1/en not_active Abandoned
- 2003-05-27 CN CNA038124912A patent/CN1656067A/zh active Pending
- 2003-05-27 DE DE60326720T patent/DE60326720D1/de not_active Expired - Lifetime
- 2003-05-27 AT AT03728206T patent/ATE425963T1/de not_active IP Right Cessation
- 2003-05-27 BR BR0311365-5A patent/BR0311365A/pt not_active IP Right Cessation
- 2003-05-27 ES ES03728206T patent/ES2322048T3/es not_active Expired - Lifetime
- 2003-05-27 JP JP2004509651A patent/JP4541140B2/ja not_active Expired - Fee Related
- 2003-05-27 NZ NZ536738A patent/NZ536738A/en not_active IP Right Cessation
- 2003-05-27 MX MXPA04011912A patent/MXPA04011912A/es active IP Right Grant
- 2003-05-27 KR KR10-2004-7019439A patent/KR20050009726A/ko not_active Application Discontinuation
- 2003-05-27 NZ NZ554323A patent/NZ554323A/en not_active IP Right Cessation
- 2003-05-27 DK DK03728206T patent/DK1513806T3/da active
- 2003-05-27 US US10/516,422 patent/US7273858B2/en not_active Expired - Fee Related
- 2003-05-27 IL IL16529503A patent/IL165295A0/xx unknown
- 2003-05-27 RU RU2004133388/04A patent/RU2345064C2/ru not_active IP Right Cessation
- 2003-05-27 UA UA20041109441A patent/UA81246C2/uk unknown
- 2003-05-27 CN CN200910260483A patent/CN101735131A/zh active Pending
- 2003-05-27 WO PCT/SE2003/000859 patent/WO2003101957A1/en active Application Filing
- 2003-05-27 EP EP09151657A patent/EP2055696A1/en not_active Withdrawn
- 2003-05-27 SI SI200331578T patent/SI1513806T1/sl unknown
- 2003-05-27 PL PL03373794A patent/PL373794A1/xx not_active Application Discontinuation
- 2003-05-27 PT PT03728206T patent/PT1513806E/pt unknown
- 2003-05-29 MY MYPI20031981A patent/MY133333A/en unknown
- 2003-05-30 AR ARP030101935A patent/AR039937A1/es unknown
- 2003-05-30 TW TW092114807A patent/TWI313173B/zh active
- 2003-05-30 TW TW097151265A patent/TWI367754B/zh not_active IP Right Cessation
- 2003-12-10 SA SA3240440A patent/SA03240440B1/ar unknown
-
2004
- 2004-11-09 NO NO20044867A patent/NO329064B1/no not_active IP Right Cessation
- 2004-11-17 ZA ZA200409228A patent/ZA200409228B/en unknown
- 2004-12-15 IS IS7598A patent/IS7598A/is unknown
-
2005
- 2005-06-20 HK HK05105118.1A patent/HK1073102A1/xx not_active IP Right Cessation
-
2007
- 2007-08-16 US US11/839,842 patent/US7763597B2/en not_active Expired - Fee Related
-
2008
- 2008-07-09 RU RU2008127541/04A patent/RU2008127541A/ru not_active Application Discontinuation
-
2009
- 2009-05-20 CY CY20091100535T patent/CY1109085T1/el unknown
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