ZA200408990B - Combination of a DPP IV inhibitor and a cardiovascular compound - Google Patents
Combination of a DPP IV inhibitor and a cardiovascular compound Download PDFInfo
- Publication number
- ZA200408990B ZA200408990B ZA200408990A ZA200408990A ZA200408990B ZA 200408990 B ZA200408990 B ZA 200408990B ZA 200408990 A ZA200408990 A ZA 200408990A ZA 200408990 A ZA200408990 A ZA 200408990A ZA 200408990 B ZA200408990 B ZA 200408990B
- Authority
- ZA
- South Africa
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- inhibitor
- dpp
- hypertension
- Prior art date
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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GBGB0212412.1A GB0212412D0 (en) | 2002-05-29 | 2002-05-29 | Combination of organic compounds |
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JP (2) | JP2005532330A (xx) |
CN (2) | CN1655786A (xx) |
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CA (1) | CA2487167A1 (xx) |
CO (1) | CO5621286A2 (xx) |
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RU (2) | RU2336876C2 (xx) |
WO (1) | WO2003099279A1 (xx) |
ZA (1) | ZA200408990B (xx) |
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CN100402026C (zh) * | 2002-06-03 | 2008-07-16 | 诺瓦提斯公司 | 取代的氰基吡咯烷和含有它们的组合制剂用于治疗高脂血症和相关疾病的用途 |
US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
US20040242566A1 (en) | 2003-03-25 | 2004-12-02 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
US20040214804A1 (en) * | 2003-04-25 | 2004-10-28 | Pharmacia Corporation | Combination of an aldosterone receptor antagonist and an anti-obesity agent |
CN1867560A (zh) | 2003-08-13 | 2006-11-22 | 武田药品工株式会社 | 4-嘧啶酮衍生物及其作为肽基肽酶抑制剂的用途 |
US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US7169926B1 (en) | 2003-08-13 | 2007-01-30 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
EP1699777B1 (en) | 2003-09-08 | 2012-12-12 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US7501426B2 (en) | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
US7732446B1 (en) | 2004-03-11 | 2010-06-08 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
CN102127053A (zh) | 2004-03-15 | 2011-07-20 | 武田药品工业株式会社 | 二肽基肽酶抑制剂 |
TW200605867A (en) * | 2004-03-17 | 2006-02-16 | Novartis Ag | Use of organic compounds |
WO2005099695A1 (en) * | 2004-04-19 | 2005-10-27 | Novartis Ag | Drug delivery systems for the prevention and treatment of vascular diseases |
US7687638B2 (en) | 2004-06-04 | 2010-03-30 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
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US20080085914A1 (en) * | 2004-10-08 | 2008-04-10 | David Louis Feldman | Use Of Organic Compounds |
DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
EP2805953B1 (en) | 2004-12-21 | 2016-03-09 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
EP2650011A1 (en) | 2004-12-24 | 2013-10-16 | Spinifex Pharmaceuticals Pty Ltd | Method of treatment or prophylaxis |
DOP2006000008A (es) | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1 |
MY146830A (en) * | 2005-02-11 | 2012-09-28 | Novartis Ag | Combination of organic compounds |
GB0503062D0 (en) * | 2005-02-14 | 2005-03-23 | Novartis Ag | Combination of organic compounds |
WO2006137222A1 (ja) * | 2005-06-24 | 2006-12-28 | Tokyo Medical And Dental University | 薬剤溶出速度制御方法、及び薬剤溶出性ステント被膜用組成物 |
DE102005035891A1 (de) | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
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CN109503584A (zh) | 2006-05-04 | 2019-03-22 | 勃林格殷格翰国际有限公司 | 多晶型 |
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US20100247491A1 (en) * | 2007-02-01 | 2010-09-30 | Christof Westenfelder | Potentiation of Stem Cell Homing and Treatment of Organ Dysfunction or Organ Failure |
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JP2010536880A (ja) | 2007-08-22 | 2010-12-02 | ギリード・コロラド・インコーポレーテッド | 糖尿病の合併症のための療法 |
EP2062874B1 (en) | 2007-11-20 | 2014-12-17 | KRKA, tovarna zdravil, d.d., Novo mesto | Process and intermediates for the preparation of aliskiren |
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SI2189442T1 (sl) | 2008-11-20 | 2015-03-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Postopek in intermediati za pripravo aliskirena |
EA022310B1 (ru) | 2008-12-23 | 2015-12-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Солевые формы органического соединения |
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WO2013171167A1 (en) | 2012-05-14 | 2013-11-21 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome |
WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
WO2014074668A1 (en) | 2012-11-08 | 2014-05-15 | Arena Pharmaceuticals, Inc. | Modulators of gpr119 and the treatment of disorders related thereto |
AU2014299575B9 (en) | 2013-06-26 | 2017-08-17 | Dong-A St Co., Ltd | Composition for preventing or treating renal diseases, containing DPP-IV inhibitor |
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JP2018507914A (ja) | 2015-03-09 | 2018-03-22 | インテクリン・セラピューティクス・インコーポレイテッド | 非アルコール性脂肪肝疾患および/またはリポジストロフィーの処置のための方法 |
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JP2020515639A (ja) | 2017-04-03 | 2020-05-28 | コヒラス・バイオサイエンシズ・インコーポレイテッド | 進行性核上性麻痺の処置のためのPPARγアゴニスト |
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WO1994003055A1 (en) * | 1992-07-31 | 1994-02-17 | The Government Of The United States Of America, Asrepresented By The Secretary Of The Department Of Health And Human Services | Producing increased numbers of hematopoietic cells by administering inhibitors of dipeptidyl peptidase iv |
US6204281B1 (en) * | 1998-07-10 | 2001-03-20 | Novartis Ag | Method of treatment and pharmaceutical composition |
IL141471A0 (en) * | 1998-08-21 | 2002-03-10 | Point Therapeutics Inc | Regulation of substrate activity |
PT1248604E (pt) * | 2000-01-21 | 2007-01-31 | Novartis Ag | Associações compreendendo inibidor de dipeptidilpeptidase-iv |
GB0014969D0 (en) * | 2000-06-19 | 2000-08-09 | Smithkline Beecham Plc | Novel method of treatment |
US20020037829A1 (en) * | 2000-08-23 | 2002-03-28 | Aronson Peter S. | Use of DPPIV inhibitors as diuretic and anti-hypertensive agents |
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2002
- 2002-05-29 GB GBGB0212412.1A patent/GB0212412D0/en not_active Ceased
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2003
- 2003-05-28 WO PCT/EP2003/005639 patent/WO2003099279A1/en active Application Filing
- 2003-05-28 CA CA002487167A patent/CA2487167A1/en not_active Abandoned
- 2003-05-28 NZ NZ536758A patent/NZ536758A/en not_active IP Right Cessation
- 2003-05-28 EP EP03755149A patent/EP1511484A1/en not_active Withdrawn
- 2003-05-28 JP JP2004506803A patent/JP2005532330A/ja not_active Withdrawn
- 2003-05-28 NZ NZ548971A patent/NZ548971A/en not_active IP Right Cessation
- 2003-05-28 AU AU2003242593A patent/AU2003242593A1/en not_active Abandoned
- 2003-05-28 PL PL03372571A patent/PL372571A1/xx not_active Application Discontinuation
- 2003-05-28 BR BR0311397-3A patent/BR0311397A/pt not_active IP Right Cessation
- 2003-05-28 RU RU2004139025/15A patent/RU2336876C2/ru not_active IP Right Cessation
- 2003-05-28 MX MXPA04011785A patent/MXPA04011785A/es active IP Right Grant
- 2003-05-28 CN CNA038121840A patent/CN1655786A/zh active Pending
- 2003-05-28 CN CNA2009100075473A patent/CN101518650A/zh active Pending
- 2003-05-28 US US10/515,864 patent/US20060074058A1/en not_active Abandoned
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2004
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- 2004-11-08 IL IL16510104A patent/IL165101A0/xx unknown
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2007
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2010
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NZ536758A (en) | 2007-02-23 |
EP1511484A1 (en) | 2005-03-09 |
CO5621286A2 (es) | 2006-03-31 |
RU2336876C2 (ru) | 2008-10-27 |
PL372571A1 (en) | 2005-07-25 |
GB0212412D0 (en) | 2002-07-10 |
RU2008119956A (ru) | 2009-11-27 |
NO20045557L (no) | 2005-02-28 |
CN101518650A (zh) | 2009-09-02 |
IL165101A0 (en) | 2005-12-18 |
JP2010090173A (ja) | 2010-04-22 |
CN1655786A (zh) | 2005-08-17 |
MXPA04011785A (es) | 2005-03-31 |
BR0311397A (pt) | 2005-03-15 |
AU2003242593A1 (en) | 2003-12-12 |
CA2487167A1 (en) | 2003-12-04 |
WO2003099279A1 (en) | 2003-12-04 |
JP2005532330A (ja) | 2005-10-27 |
US20070293474A1 (en) | 2007-12-20 |
US20060074058A1 (en) | 2006-04-06 |
NZ548971A (en) | 2008-04-30 |
RU2004139025A (ru) | 2005-09-10 |
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