ZA200408711B - Novel thiophene amidines, composition thereof, and methods of treating complement-mediated diseases and conditions - Google Patents

Novel thiophene amidines, composition thereof, and methods of treating complement-mediated diseases and conditions Download PDF

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Publication number
ZA200408711B
ZA200408711B ZA200408711A ZA200408711A ZA200408711B ZA 200408711 B ZA200408711 B ZA 200408711B ZA 200408711 A ZA200408711 A ZA 200408711A ZA 200408711 A ZA200408711 A ZA 200408711A ZA 200408711 B ZA200408711 B ZA 200408711B
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South Africa
Prior art keywords
compound
methyl
alkyl
phenyl
thiophene
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ZA200408711A
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English (en)
Inventor
Nalin Subasinghe
Kristi Leonard
Heather Rae Hufnagel
Shelley K Ballentine
Wenxi Pan
Sanath Meegalla
Jinsheng Chen
Hui Huang
Ehab Khalil
Farah Ali
Jeremy M Travins
Maxwell D Cummings
Joan Gushue
Mark Wall
Jonathan M Rudolph
Kenneth J Wilson
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Dimensional Pharamaceuticals I
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Publication of ZA200408711B publication Critical patent/ZA200408711B/en

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    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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ZA200408711A 2002-05-28 2003-05-28 Novel thiophene amidines, composition thereof, and methods of treating complement-mediated diseases and conditions ZA200408711B (en)

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US38313002P 2002-05-28 2002-05-28

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US (2) US7138530B2 (zh)
EP (1) EP1549632A4 (zh)
JP (1) JP2005538953A (zh)
KR (1) KR20050009720A (zh)
CN (1) CN100412073C (zh)
AR (1) AR039891A1 (zh)
AU (1) AU2003251384B2 (zh)
BR (1) BR0311419A (zh)
CA (1) CA2484822A1 (zh)
CO (1) CO5640081A2 (zh)
HK (1) HK1081187A1 (zh)
HR (1) HRP20041220A2 (zh)
IL (1) IL164890A0 (zh)
MX (1) MX249034B (zh)
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NO (1) NO20045403L (zh)
NZ (1) NZ537346A (zh)
PL (1) PL372246A1 (zh)
RU (1) RU2359967C2 (zh)
TW (1) TW200406395A (zh)
UA (1) UA80131C2 (zh)
WO (1) WO2003099805A1 (zh)
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EP1814875A4 (en) * 2004-10-20 2010-02-17 Univ California IMPROVED INHIBITORS OF SOLUBLE HYDROLASE EPOXYDE
SI1879573T1 (sl) 2005-05-10 2013-04-30 Incyte Corporation Experimental Station Modulatorji indolamin 2,3-dioksigenaze in postopki za uporabo le-te
KR20080016597A (ko) * 2005-05-13 2008-02-21 바이로켐 파마 인코포레이티드 플라비바이러스 감염의 예방 또는 치료용 화합물 및 그의예방 또는 치료 방법
ES2540561T3 (es) * 2005-12-20 2015-07-10 Incyte Corporation N-hidroxiamidinoheterociclos como moduladores de indolamina 2,3-dioxigenasa
MX335993B (es) * 2005-12-30 2016-01-07 Anacor Pharmaceuticals Inc Moleculas pequeñas que contienen boro.
PL1988779T3 (pl) 2006-02-16 2015-10-30 Anacor Pharmaceuticals Inc Małe cząsteczki zawierające bor jako środki przeciwzapalne
JP5319532B2 (ja) 2006-09-19 2013-10-16 インサイト・コーポレイション インドールアミン２，３−ジオキシゲナーゼのモジュレーターとしてのｎ−ヒドロキシアミジノヘテロサイクル
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