ZA200403573B - Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents - Google Patents

Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents Download PDF

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Publication number
ZA200403573B
ZA200403573B ZA2004/03573A ZA200403573A ZA200403573B ZA 200403573 B ZA200403573 B ZA 200403573B ZA 2004/03573 A ZA2004/03573 A ZA 2004/03573A ZA 200403573 A ZA200403573 A ZA 200403573A ZA 200403573 B ZA200403573 B ZA 200403573B
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South Africa
Prior art keywords
agents
antibody
cells
tra
therapeutic agent
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ZA2004/03573A
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English (en)
Inventor
Ichikawa Kimihisa
Zhou Tong
P Kimberly Robert
KOOPMAN WilliamJ
F Lobuglio Albert
J Buchsbaum Donald
Oshumi Jun
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Uab Res Found
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Publication of ZA200403573B publication Critical patent/ZA200403573B/en

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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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ZA2004/03573A 2001-11-01 2004-05-11 Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents ZA200403573B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34640201P 2001-11-01 2001-11-01
US39147802P 2002-06-24 2002-06-24
PCT/US2002/034420 WO2003038043A2 (en) 2001-11-01 2002-10-25 Combinations of dr5 antibody and other therapeutic agents

Publications (1)

Publication Number Publication Date
ZA200403573B true ZA200403573B (en) 2005-08-31

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ZA2004/03573A ZA200403573B (en) 2001-11-01 2004-05-11 Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents

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EP (1) EP1506285B1 (https=)
JP (1) JP4663232B2 (https=)
KR (1) KR20040081422A (https=)
CN (1) CN100506277C (https=)
AT (1) ATE491019T1 (https=)
AU (1) AU2002360307B2 (https=)
BR (1) BRPI0213846B8 (https=)
CA (1) CA2465314C (https=)
CO (1) CO5650175A2 (https=)
DE (1) DE60238560D1 (https=)
HU (1) HU230378B1 (https=)
IL (2) IL161686A0 (https=)
MX (1) MXPA04004184A (https=)
NO (1) NO333828B1 (https=)
NZ (2) NZ568727A (https=)
PL (1) PL216750B1 (https=)
RO (1) RO123525B1 (https=)
RU (1) RU2313368C2 (https=)
WO (1) WO2003038043A2 (https=)
ZA (1) ZA200403573B (https=)

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AU2003222427B8 (en) 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
US7115717B2 (en) 2001-05-18 2006-10-03 Kirin Beer Kabushiki Kaisha Anti-TRAIL-R antibodies
US7361341B2 (en) 2001-05-25 2008-04-22 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to trail receptors
US7348003B2 (en) 2001-05-25 2008-03-25 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors
EP1409544B1 (en) 2001-07-03 2009-06-17 Genentech, Inc. Human dr4 antibodies and uses thereof
CN100506284C (zh) 2001-10-19 2009-07-01 脉管生物生长有限公司 多核苷酸构建体、药物组合物以及靶向的下调血管生成和抗癌的治疗方法
KR20090046973A (ko) * 2002-11-27 2009-05-11 아이알엠 엘엘씨 암세포에서 세포자멸사를 유도하기 위한 방법 및 조성물
AU2008201431B2 (en) * 2002-11-27 2011-11-24 Irm, Llc Methods and compositions for inducing Apoptosis in cancer cells
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JP2007508332A (ja) * 2003-10-17 2007-04-05 ノボ　ノルディスク　アクティーゼルスカブ 併用療法
KR20070010046A (ko) * 2004-04-06 2007-01-19 제넨테크, 인크. Ｄｒ5 항체 및 그의 용도
CN101061238B (zh) 2004-08-06 2013-11-20 健泰科生物技术公司 使用生物标志的测定法和方法
MX2007001469A (es) 2004-08-06 2007-03-26 Genentech Inc Ensayos y metodos que utilizan biomarcadores.
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