NZ568727A - Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents - Google Patents

Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents

Info

Publication number
NZ568727A
NZ568727A NZ568727A NZ56872702A NZ568727A NZ 568727 A NZ568727 A NZ 568727A NZ 568727 A NZ568727 A NZ 568727A NZ 56872702 A NZ56872702 A NZ 56872702A NZ 568727 A NZ568727 A NZ 568727A
Authority
NZ
New Zealand
Prior art keywords
agents
antibody
cells
tra
apoptosis
Prior art date
Application number
NZ568727A
Other languages
English (en)
Inventor
Tong Zhou
Kimihisa Ichikawa
Robert P Kimberley
William J Koopman
Jun Oshumi
Albert F Lobuglio
Donald J Buchsbaum
Original Assignee
Uab Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uab Research Foundation filed Critical Uab Research Foundation
Publication of NZ568727A publication Critical patent/NZ568727A/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
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  • Molecular Biology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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NZ568727A 2001-11-01 2002-10-25 Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents NZ568727A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34640201P 2001-11-01 2001-11-01
US39147802P 2002-06-24 2002-06-24

Publications (1)

Publication Number Publication Date
NZ568727A true NZ568727A (en) 2009-08-28

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NZ568727A NZ568727A (en) 2001-11-01 2002-10-25 Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents
NZ533164A NZ533164A (en) 2001-11-01 2002-10-25 Combinations of antibodies selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and other therapeutic agents

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Country Link
EP (1) EP1506285B1 (https=)
JP (1) JP4663232B2 (https=)
KR (1) KR20040081422A (https=)
CN (1) CN100506277C (https=)
AT (1) ATE491019T1 (https=)
AU (1) AU2002360307B2 (https=)
BR (1) BRPI0213846B8 (https=)
CA (1) CA2465314C (https=)
CO (1) CO5650175A2 (https=)
DE (1) DE60238560D1 (https=)
HU (1) HU230378B1 (https=)
IL (2) IL161686A0 (https=)
MX (1) MXPA04004184A (https=)
NO (1) NO333828B1 (https=)
NZ (2) NZ568727A (https=)
PL (1) PL216750B1 (https=)
RO (1) RO123525B1 (https=)
RU (1) RU2313368C2 (https=)
WO (1) WO2003038043A2 (https=)
ZA (1) ZA200403573B (https=)

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TWI318983B (en) 2000-05-02 2010-01-01 Uab Research Foundation An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof
AU2003222427B8 (en) 2000-11-17 2010-04-29 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
US7115717B2 (en) 2001-05-18 2006-10-03 Kirin Beer Kabushiki Kaisha Anti-TRAIL-R antibodies
US7361341B2 (en) 2001-05-25 2008-04-22 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to trail receptors
US7348003B2 (en) 2001-05-25 2008-03-25 Human Genome Sciences, Inc. Methods of treating cancer using antibodies that immunospecifically bind to TRAIL receptors
EP1409544B1 (en) 2001-07-03 2009-06-17 Genentech, Inc. Human dr4 antibodies and uses thereof
CN100506284C (zh) 2001-10-19 2009-07-01 脉管生物生长有限公司 多核苷酸构建体、药物组合物以及靶向的下调血管生成和抗癌的治疗方法
KR20090046973A (ko) * 2002-11-27 2009-05-11 아이알엠 엘엘씨 암세포에서 세포자멸사를 유도하기 위한 방법 및 조성물
AU2008201431B2 (en) * 2002-11-27 2011-11-24 Irm, Llc Methods and compositions for inducing Apoptosis in cancer cells
US20060228331A1 (en) 2003-10-10 2006-10-12 Novo Nordisk A/S IL-21 Derivatives and variants
JP2007508332A (ja) * 2003-10-17 2007-04-05 ノボ　ノルディスク　アクティーゼルスカブ 併用療法
KR20070010046A (ko) * 2004-04-06 2007-01-19 제넨테크, 인크. Ｄｒ5 항체 및 그의 용도
CN101061238B (zh) 2004-08-06 2013-11-20 健泰科生物技术公司 使用生物标志的测定法和方法
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