RS60558B1 - Pentaaza makrociklični prstenasti kompleksi koji poseduju oralnu bioraspoloživost - Google Patents
Pentaaza makrociklični prstenasti kompleksi koji poseduju oralnu bioraspoloživostInfo
- Publication number
- RS60558B1 RS60558B1 RS20200860A RSP20200860A RS60558B1 RS 60558 B1 RS60558 B1 RS 60558B1 RS 20200860 A RS20200860 A RS 20200860A RS P20200860 A RSP20200860 A RS P20200860A RS 60558 B1 RS60558 B1 RS 60558B1
- Authority
- RS
- Serbia
- Prior art keywords
- oral bioavailability
- macrocyclic ring
- pentaaza macrocyclic
- ring complexes
- complexes possessing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic System
- C07F1/08—Copper compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
- C07F15/02—Iron compounds
- C07F15/025—Iron compounds without a metal-carbon linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
- C07F15/04—Nickel compounds
- C07F15/045—Nickel compounds without a metal-carbon linkage
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562203761P | 2015-08-11 | 2015-08-11 | |
| EP16835928.9A EP3334744B1 (en) | 2015-08-11 | 2016-08-11 | Pentaaza macrocyclic ring complexes possessing oral bioavailability |
| PCT/US2016/046599 WO2017027728A1 (en) | 2015-08-11 | 2016-08-11 | Pentaaza macrocyclic ring complexes possessing oral bioavailability |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS60558B1 true RS60558B1 (sr) | 2020-08-31 |
Family
ID=57984526
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20200860A RS60558B1 (sr) | 2015-08-11 | 2016-08-11 | Pentaaza makrociklični prstenasti kompleksi koji poseduju oralnu bioraspoloživost |
Country Status (29)
| Country | Link |
|---|---|
| US (5) | US10597415B2 (sr) |
| EP (2) | EP3738967A1 (sr) |
| JP (3) | JP7041959B2 (sr) |
| KR (1) | KR20180064380A (sr) |
| CN (3) | CN113416170A (sr) |
| AU (3) | AU2016306568B2 (sr) |
| CA (1) | CA2994845A1 (sr) |
| CL (1) | CL2018000371A1 (sr) |
| CO (1) | CO2018002544A2 (sr) |
| CY (1) | CY1123960T1 (sr) |
| DK (1) | DK3334744T3 (sr) |
| EA (1) | EA201890471A1 (sr) |
| ES (1) | ES2807528T3 (sr) |
| HK (1) | HK1257313A1 (sr) |
| HR (1) | HRP20201092T1 (sr) |
| HU (1) | HUE049926T2 (sr) |
| IL (3) | IL297735B1 (sr) |
| LT (1) | LT3334744T (sr) |
| MX (2) | MX2018001605A (sr) |
| MY (1) | MY196401A (sr) |
| PH (1) | PH12018500296A1 (sr) |
| PL (1) | PL3334744T3 (sr) |
| PT (1) | PT3334744T (sr) |
| RS (1) | RS60558B1 (sr) |
| SG (1) | SG10202002859QA (sr) |
| SI (1) | SI3334744T1 (sr) |
| UA (1) | UA126788C2 (sr) |
| WO (1) | WO2017027728A1 (sr) |
| ZA (2) | ZA201801546B (sr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2056675T (lt) | 2006-10-12 | 2019-05-27 | Galera Labs, Llc | Burnos gleivinės mukozito gydymo būdai |
| WO2013048965A1 (en) | 2011-09-26 | 2013-04-04 | Galera Therapeutics, Llc | Methods for treatment of diseases |
| EA201890471A1 (ru) | 2015-08-11 | 2018-10-31 | ГАЛЕРА ЛЭБЗ, ЭлЭлСи | Комплексные соединения, содержащие макроциклическое кольцо пентаазы, обладающие пероральной биодоступностью |
| CN109906081A (zh) | 2016-09-01 | 2019-06-18 | 加莱拉实验室有限责任公司 | 利用五氮杂大环络合物和抗坏血酸类化合物的联合癌症疗法 |
| WO2018152353A2 (en) | 2017-02-15 | 2018-08-23 | Galera Labs, Llc | Pentaaza macrocyclic ring complexes for local intestinal delivery |
| CA3059581A1 (en) * | 2017-04-13 | 2018-10-18 | Galera Labs, Llc | Combination cancer immunotherapy with pentaaza macrocyclic ring complex |
| EA201992431A1 (ru) | 2017-10-13 | 2020-03-13 | ГАЛЕРА ЛЭБЗ, ЭлЭлСи | Комбинированная иммунотерапия рака с использованием пента-аза-макроциклического кольцевого комплекса |
| JP2022551494A (ja) * | 2019-10-10 | 2022-12-09 | ガレラ・ラブス・リミテッド・ライアビリティ・カンパニー | マンガン含有配位錯体の水性製剤の製造方法、製剤および処置方法 |
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2016
- 2016-08-11 EA EA201890471A patent/EA201890471A1/ru unknown
- 2016-08-11 MX MX2018001605A patent/MX2018001605A/es unknown
- 2016-08-11 KR KR1020187006846A patent/KR20180064380A/ko not_active Application Discontinuation
- 2016-08-11 CN CN202110688812.XA patent/CN113416170A/zh active Pending
- 2016-08-11 WO PCT/US2016/046599 patent/WO2017027728A1/en active Application Filing
- 2016-08-11 CN CN202110688814.9A patent/CN113402560A/zh active Pending
- 2016-08-11 CA CA2994845A patent/CA2994845A1/en active Pending
- 2016-08-11 HU HUE16835928A patent/HUE049926T2/hu unknown
- 2016-08-11 MY MYPI2018700525A patent/MY196401A/en unknown
- 2016-08-11 SG SG10202002859QA patent/SG10202002859QA/en unknown
- 2016-08-11 PT PT168359289T patent/PT3334744T/pt unknown
- 2016-08-11 LT LTEP16835928.9T patent/LT3334744T/lt unknown
- 2016-08-11 AU AU2016306568A patent/AU2016306568B2/en active Active
- 2016-08-11 EP EP20168046.9A patent/EP3738967A1/en active Pending
- 2016-08-11 US US15/751,495 patent/US10597415B2/en active Active
- 2016-08-11 DK DK16835928.9T patent/DK3334744T3/da active
- 2016-08-11 CN CN201680058867.XA patent/CN108350009B/zh active Active
- 2016-08-11 UA UAA201802349A patent/UA126788C2/uk unknown
- 2016-08-11 RS RS20200860A patent/RS60558B1/sr unknown
- 2016-08-11 EP EP16835928.9A patent/EP3334744B1/en active Active
- 2016-08-11 ES ES16835928T patent/ES2807528T3/es active Active
- 2016-08-11 IL IL297735A patent/IL297735B1/en unknown
- 2016-08-11 PL PL16835928T patent/PL3334744T3/pl unknown
- 2016-08-11 JP JP2018506866A patent/JP7041959B2/ja active Active
- 2016-08-11 SI SI201630852T patent/SI3334744T1/sl unknown
- 2016-08-25 US US15/246,830 patent/US9738670B2/en active Active
- 2016-08-25 US US15/246,788 patent/US9738669B2/en active Active
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2018
- 2018-02-04 IL IL257346A patent/IL257346B/en unknown
- 2018-02-07 MX MX2022010230A patent/MX2022010230A/es unknown
- 2018-02-09 PH PH12018500296A patent/PH12018500296A1/en unknown
- 2018-02-09 CL CL2018000371A patent/CL2018000371A1/es unknown
- 2018-03-06 ZA ZA2018/01546A patent/ZA201801546B/en unknown
- 2018-03-09 CO CONC2018/0002544A patent/CO2018002544A2/es unknown
- 2018-12-21 HK HK18116470.5A patent/HK1257313A1/zh unknown
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2020
- 2020-03-04 ZA ZA2020/01373A patent/ZA202001373B/en unknown
- 2020-03-09 US US16/812,740 patent/US11066433B2/en active Active
- 2020-07-13 HR HRP20201092TT patent/HRP20201092T1/hr unknown
- 2020-07-21 CY CY20201100665T patent/CY1123960T1/el unknown
- 2020-12-15 AU AU2020289730A patent/AU2020289730B2/en active Active
-
2021
- 2021-07-19 US US17/378,852 patent/US20210347796A1/en active Pending
- 2021-10-25 IL IL287546A patent/IL287546B2/en unknown
- 2021-10-28 JP JP2021176312A patent/JP2022023183A/ja active Pending
-
2023
- 2023-02-10 AU AU2023200738A patent/AU2023200738A1/en active Pending
- 2023-10-27 JP JP2023184571A patent/JP2024012401A/ja active Pending
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