ZA200401108B - Biologically active peptides - Google Patents

Biologically active peptides Download PDF

Info

Publication number
ZA200401108B
ZA200401108B ZA200401108A ZA200401108A ZA200401108B ZA 200401108 B ZA200401108 B ZA 200401108B ZA 200401108 A ZA200401108 A ZA 200401108A ZA 200401108 A ZA200401108 A ZA 200401108A ZA 200401108 B ZA200401108 B ZA 200401108B
Authority
ZA
South Africa
Prior art keywords
peptide
amino acid
acid sequence
group
seq
Prior art date
Application number
ZA200401108A
Other languages
English (en)
Inventor
Wai M Wong
Gang Lin
Original Assignee
Pepharm R & D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pepharm R & D Ltd filed Critical Pepharm R & D Ltd
Publication of ZA200401108B publication Critical patent/ZA200401108B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4716Muscle proteins, e.g. myosin, actin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • C07K14/805Haemoglobins; Myoglobins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1024Tetrapeptides with the first amino acid being heterocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA200401108A 2001-07-13 2004-02-11 Biologically active peptides ZA200401108B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US90449201A 2001-07-13 2001-07-13

Publications (1)

Publication Number Publication Date
ZA200401108B true ZA200401108B (en) 2006-05-31

Family

ID=25419251

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200401108A ZA200401108B (en) 2001-07-13 2004-02-11 Biologically active peptides
ZA200509838A ZA200509838B (en) 2001-07-13 2005-12-05 Biologically active peptides

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA200509838A ZA200509838B (en) 2001-07-13 2005-12-05 Biologically active peptides

Country Status (24)

Country Link
EP (3) EP1947109A3 (da)
JP (3) JP4213581B2 (da)
KR (2) KR100889993B1 (da)
AT (2) ATE414099T1 (da)
AU (1) AU2002319423B2 (da)
BR (1) BR0210252A (da)
CA (2) CA2707767C (da)
DE (2) DE60229883D1 (da)
DK (2) DK1790655T3 (da)
ES (2) ES2316586T3 (da)
HK (2) HK1066552A1 (da)
IL (2) IL159827A0 (da)
MX (1) MXPA03011190A (da)
MY (1) MY138219A (da)
NO (2) NO332061B1 (da)
NZ (3) NZ544079A (da)
PL (2) PL208666B1 (da)
PT (2) PT1790655E (da)
RU (2) RU2305107C2 (da)
SA (1) SA04240478B1 (da)
SG (2) SG142165A1 (da)
UA (1) UA83989C2 (da)
WO (1) WO2003006492A2 (da)
ZA (2) ZA200401108B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1210298C (zh) 2001-07-13 2005-07-13 一泰医药研究(深圳)有限公司 序列号1的生物活性肽
WO2004055042A1 (en) * 2002-12-18 2004-07-01 Pepharm R & D Limited Biologically active peptide conjugates
TWI322815B (en) * 2003-06-26 2010-04-01 Cms Peptides Patent Holding Company Ltd Biologically active peptide comprising tyrosyl-seryl-valine (ysv)
TWI353252B (en) * 2004-04-28 2011-12-01 Cms Peptides Patent Holding Company Ltd Biologically active peptide vapeehptllteaplnpk der
CN1799623B (zh) * 2005-01-05 2011-01-26 康哲医药研究(深圳)有限公司 生物活性肽在制备用于防治关节炎的药物中的用途
RU2423375C2 (ru) * 2005-07-26 2011-07-10 СиЭмЭс ПЕПТАЙДЗ ПЭЙТЕНТ ХОЛДИНГ КОМПАНИ ЛИМИТЕД Новые биологически активные пептиды и их новое применение
GB0918579D0 (en) 2009-10-22 2009-12-09 Imp Innovations Ltd Gadd45beta targeting agents
RU2615908C1 (ru) * 2016-05-16 2017-04-11 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Способ моделирования лимфогенного и гематогенного метастазирования мышиной меланомы В16 у белых нелинейных крыс

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242821A (en) 1989-07-10 1993-09-07 Valio, Finnish Co-Operative Dairies' Association Lactococcus promoter and signal sequences for expression in bacteria
IT1231156B (it) 1989-07-19 1991-11-19 Eniricerche Spa Espressione e secrezione di interleuchina 1 beta umana matura in bacillus subtilis e mezzi e metodi per il suo ottenimento.
WO1991009613A1 (en) * 1989-12-22 1991-07-11 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Synthetic peptides as modulators of functional responses of intact cells
US5556744A (en) * 1992-05-29 1996-09-17 The Trustees Of The University Of Pennsylvania Methods and compositions for diagnosing and treating certain HIV infected patients
DE69433299T2 (de) 1993-06-15 2004-09-09 E.I. Du Pont De Nemours And Co., Wilmington Rekombinante spinnerseide analoge
JP3286420B2 (ja) 1993-09-28 2002-05-27 株式会社ユニシアジェックス 内燃機関の吸排気弁駆動制御装置
AU2631695A (en) 1994-06-17 1996-01-15 Nederlandse Organisatie Voor Toegepast- Natuurwetenschappelijk Onderzoek Tno Method for introduction of genetic material into microorganisms and transformants obtained therewith
US6184208B1 (en) 1994-06-29 2001-02-06 Immunotech Developments Inc. Peptide, a method for its preparation and a pharmaceutical composition containing the peptide
US5958416A (en) * 1994-12-16 1999-09-28 Regents Of The University Of Minnesota Heat shock protein peptides and methods for modulating autoimmune central nervous system disease
IL115199A (en) 1995-09-07 2005-05-17 Opperbas Holding Bv Composition comprising a polynucleic acid molecule in a liposome and method using said composition
CA2232240C (en) 1995-10-24 2007-01-16 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Peptide for inhibiting growth of smooth muscle cells
GB9606016D0 (en) * 1996-03-22 1996-05-22 Smithkline Beecham Plc Novel use
US5861483A (en) 1996-04-03 1999-01-19 Pro-Neuron, Inc. Inhibitor of stem cell proliferation and uses thereof
SE9603468D0 (sv) * 1996-09-23 1996-09-23 Astra Ab New compounds
GB9710762D0 (en) * 1997-05-23 1997-07-23 Cancer Res Inst Royal Binding complexes
WO1998054339A1 (en) 1997-05-27 1998-12-03 Hanil Synthetic Fiber Co., Ltd. PROCESS FOR PREPARING RECOMBINANT PROTEINS USING HIGHLY EFFICIENT EXPRESSION VECTOR FROM $i(SACCHAROMYCES CEREVISIAE)
KR19990024297A (ko) 1997-08-07 1999-04-06 오종석 인체 구강내 치태형성을 억제하는 신규한 유산균
US6100388A (en) 1998-03-16 2000-08-08 Biogaia Biologies Ab Lactobacilli harboring aggregation gene as a vaccine delivery vehicle
US6245427B1 (en) 1998-07-06 2001-06-12 DüZGüNES NEJAT Non-ligand polypeptide and liposome complexes as intracellular delivery vehicles
WO2000013025A1 (en) * 1998-08-31 2000-03-09 University Of Washington Stable isotope metabolic labeling for analysis of biopolymers
US6413530B1 (en) * 1999-04-21 2002-07-02 University Of Florida Research Foundation, Inc. Pesticidal peptides
FR2794370B1 (fr) * 1999-06-03 2003-10-17 Biovector Therapeutics Fragments proteiques polyepitopiques, leur obtention et leurs utilisations notamment en vaccination
WO2001032853A1 (en) * 1999-10-29 2001-05-10 Institute For Applied Biomedicine B cell clonal toxins and methods for using the same

Also Published As

Publication number Publication date
UA83989C2 (ru) 2008-09-10
NO20040134L (no) 2004-03-10
ZA200509838B (en) 2007-11-28
NZ544079A (en) 2007-10-26
IL184227A0 (en) 2007-10-31
CA2707767A1 (en) 2003-01-23
MXPA03011190A (es) 2004-10-28
ES2316586T3 (es) 2009-04-16
DK1790655T3 (da) 2010-08-23
SG142165A1 (en) 2008-05-28
KR100889993B1 (ko) 2009-03-25
SG185137A1 (en) 2012-11-29
DE60236330D1 (de) 2010-06-17
CA2452417C (en) 2013-08-20
RU2425053C2 (ru) 2011-07-27
KR100889992B1 (ko) 2009-03-25
EP1790655A3 (en) 2007-10-10
NO20073914L (no) 2004-03-10
HK1066552A1 (en) 2005-03-24
NZ553507A (en) 2008-07-31
EP1790655A2 (en) 2007-05-30
HK1098767A1 (en) 2007-07-27
JP4213581B2 (ja) 2009-01-21
EP1947109A2 (en) 2008-07-23
EP1478659B1 (en) 2008-11-12
RU2004104335A (ru) 2005-03-27
ATE414099T1 (de) 2008-11-15
JP2008263993A (ja) 2008-11-06
CA2452417A1 (en) 2003-01-23
IL184227A (en) 2010-06-16
MY138219A (en) 2009-05-29
RU2007108896A (ru) 2008-09-20
NO332061B1 (no) 2012-06-11
BR0210252A (pt) 2004-09-14
WO2003006492A2 (en) 2003-01-23
PL208666B1 (pl) 2011-05-31
JP4316651B2 (ja) 2009-08-19
EP1790655B1 (en) 2010-05-05
ES2345842T3 (es) 2010-10-04
IL159827A0 (en) 2004-06-20
JP2004533846A (ja) 2004-11-11
PT1790655E (pt) 2010-07-09
KR20070070258A (ko) 2007-07-03
PL368059A1 (en) 2005-03-21
SA04240478B1 (ar) 2007-07-31
EP1947109A3 (en) 2008-10-01
RU2305107C2 (ru) 2007-08-27
KR20040019058A (ko) 2004-03-04
NZ529879A (en) 2007-12-21
WO2003006492A3 (en) 2003-12-31
PL211884B1 (pl) 2012-07-31
DE60229883D1 (de) 2008-12-24
JP2007312785A (ja) 2007-12-06
ATE466871T1 (de) 2010-05-15
DK1478659T3 (da) 2009-01-05
PT1478659E (pt) 2009-01-02
CA2707767C (en) 2013-09-03
EP1478659A2 (en) 2004-11-24
AU2002319423B2 (en) 2008-02-14

Similar Documents

Publication Publication Date Title
CN100366742C (zh) Il-2选择性激动剂和拮抗剂
EP1315513B1 (en) "pseudo"-native chemical ligation
RU2292352C2 (ru) Ингибитор и стимулятор пролиферации стволовой клетки и их использование
TW458984B (en) Novel mutant hIL-4 proteins as antagonists or partial agonists of human interleukin 4
EA021867B1 (ru) Иммуномодулирующие полипептиды, полученные из il-2, и их применение для лечения рака и хронических инфекций
HU218007B (hu) Eljárás random bio-oligomer könyvtár előállítására valamint, alkalmazására
EP0335423A2 (en) Modified human G-CSF
US10875903B2 (en) Bifunctional fusion proteins to inhibit angiogenesis in tumor microenvironment and to activate adaptive immune responses and the genes and uses thereof
CN101432428A (zh) 重组人干扰素样蛋白
EA003940B1 (ru) Усеченный по амино-концу хемокин rantes и способы его использования
JPS62174026A (ja) 白血球減少症治療剤
ZA200401108B (en) Biologically active peptides
CN111620932A (zh) 一种多肽及在促进nk细胞增殖和提高其对肿瘤细胞杀伤力方面的应用
CN111718399A (zh) 一种多肽及用于nk细胞培养、制备nk细胞培养基的用途
CA2301499A1 (en) T-cell membrane protein (tirc7), peptides and antibodies derived therefrom and uses thereof
CN102131518B (zh) 包含白介素-11类似物的生物聚合物缀合物
CN102775502A (zh) α干扰素融合蛋白
EP0138616A2 (en) Nona- and dodecapeptides for augmenting natural killer cell activity, processes for making them and pharmaceutical compositions comprising them
CN106928335A (zh) 用于肿瘤的Her-2多肽、组合物及制备方法和应用
JP2000264900A (ja) 新規生理活性ペプチド
CN111499723B (zh) 一种嵌合抗原受体及其应用
CN101142234A (zh) 结合红细胞生成素受体的新肽
CN102168057B (zh) 表达多活性肽的工程菌及制备混合多肽的方法
JPH0474197A (ja) 新規な免疫調整生理活性ペプチド
RU2601126C2 (ru) Способ получения биологически активных пептидов