UA83989C2 - Выделенный пептид, который стимулирует противоопухолевый иммунный ответ, фармацевтическая композиция на его основе и ее применение - Google Patents

Выделенный пептид, который стимулирует противоопухолевый иммунный ответ, фармацевтическая композиция на его основе и ее применение

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Publication number
UA83989C2
UA83989C2 UA2004021049A UA2004021049A UA83989C2 UA 83989 C2 UA83989 C2 UA 83989C2 UA 2004021049 A UA2004021049 A UA 2004021049A UA 2004021049 A UA2004021049 A UA 2004021049A UA 83989 C2 UA83989 C2 UA 83989C2
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UA
Ukraine
Prior art keywords
pharmaceutical composition
immune response
tumor immune
isolated peptide
composition based
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UA2004021049A
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English (en)
Ukrainian (uk)
Inventor
Вей Минг Вонг
Конг ЛAM
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Си-Эм-Эс Пептидес Патент Холдинг Компани Лимитед
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Publication of UA83989C2 publication Critical patent/UA83989C2/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4716Muscle proteins, e.g. myosin, actin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795Porphyrin- or corrin-ring-containing peptides
    • C07K14/805Haemoglobins; Myoglobins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1024Tetrapeptides with the first amino acid being heterocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Изобретение относится к выделенному пептиду, который стимулирует противоопухолевый иммунный ответ и имеет аминокислотную последовательность Tyr-Ser-Leu, фармацевтической композиции, которая состоит из эффективного количества указанного пептида, и применению указанной фармацевтической композиции для лечения млекопитающих, у которых диагностирован рак, в частности рак печени или меланома.
UA2004021049A 2001-07-13 2002-07-11 Выделенный пептид, который стимулирует противоопухолевый иммунный ответ, фармацевтическая композиция на его основе и ее применение UA83989C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90449201A 2001-07-13 2001-07-13
PCT/GB2002/003203 WO2003006492A2 (en) 2001-07-13 2002-07-11 Biologically active peptides

Publications (1)

Publication Number Publication Date
UA83989C2 true UA83989C2 (ru) 2008-09-10

Family

ID=25419251

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2004021049A UA83989C2 (ru) 2001-07-13 2002-07-11 Выделенный пептид, который стимулирует противоопухолевый иммунный ответ, фармацевтическая композиция на его основе и ее применение

Country Status (24)

Country Link
EP (3) EP1947109A3 (ru)
JP (3) JP4213581B2 (ru)
KR (2) KR100889992B1 (ru)
AT (2) ATE466871T1 (ru)
AU (1) AU2002319423B2 (ru)
BR (1) BR0210252A (ru)
CA (2) CA2452417C (ru)
DE (2) DE60229883D1 (ru)
DK (2) DK1790655T3 (ru)
ES (2) ES2316586T3 (ru)
HK (2) HK1066552A1 (ru)
IL (2) IL159827A0 (ru)
MX (1) MXPA03011190A (ru)
MY (1) MY138219A (ru)
NO (2) NO332061B1 (ru)
NZ (3) NZ544079A (ru)
PL (2) PL211884B1 (ru)
PT (2) PT1790655E (ru)
RU (2) RU2305107C2 (ru)
SA (1) SA04240478B1 (ru)
SG (2) SG185137A1 (ru)
UA (1) UA83989C2 (ru)
WO (1) WO2003006492A2 (ru)
ZA (2) ZA200401108B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
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CN1213062C (zh) 2001-07-13 2005-08-03 一泰医药研究(深圳)有限公司 序列号13的生物活性肽
US20060167229A1 (en) * 2002-12-18 2006-07-27 Wai Ming Wong Biologically active peptide conjugates
TWI322815B (en) * 2003-06-26 2010-04-01 Cms Peptides Patent Holding Company Ltd Biologically active peptide comprising tyrosyl-seryl-valine (ysv)
TWI353252B (en) 2004-04-28 2011-12-01 Cms Peptides Patent Holding Company Ltd Biologically active peptide vapeehptllteaplnpk der
CN1799623B (zh) * 2005-01-05 2011-01-26 康哲医药研究(深圳)有限公司 生物活性肽在制备用于防治关节炎的药物中的用途
EP1909815A4 (en) 2005-07-26 2011-05-18 Cms Peptides Patent Holding Company Ltd NEW BIOLOGICALLY ACTIVE PEPTIDES AND THEIR NEW USES
GB0918579D0 (en) * 2009-10-22 2009-12-09 Imp Innovations Ltd Gadd45beta targeting agents
RU2615908C1 (ru) * 2016-05-16 2017-04-11 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Способ моделирования лимфогенного и гематогенного метастазирования мышиной меланомы В16 у белых нелинейных крыс

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US5556744A (en) * 1992-05-29 1996-09-17 The Trustees Of The University Of Pennsylvania Methods and compositions for diagnosing and treating certain HIV infected patients
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Also Published As

Publication number Publication date
NO20073914L (no) 2004-03-10
BR0210252A (pt) 2004-09-14
EP1790655A2 (en) 2007-05-30
HK1066552A1 (en) 2005-03-24
RU2004104335A (ru) 2005-03-27
ATE466871T1 (de) 2010-05-15
PL208666B1 (pl) 2011-05-31
DE60236330D1 (de) 2010-06-17
WO2003006492A2 (en) 2003-01-23
DE60229883D1 (de) 2008-12-24
JP4316651B2 (ja) 2009-08-19
CA2707767A1 (en) 2003-01-23
ES2345842T3 (es) 2010-10-04
KR100889992B1 (ko) 2009-03-25
CA2707767C (en) 2013-09-03
EP1790655B1 (en) 2010-05-05
CA2452417C (en) 2013-08-20
NO332061B1 (no) 2012-06-11
JP4213581B2 (ja) 2009-01-21
EP1947109A3 (en) 2008-10-01
SA04240478B1 (ar) 2007-07-31
PL211884B1 (pl) 2012-07-31
WO2003006492A3 (en) 2003-12-31
KR20070070258A (ko) 2007-07-03
PL368059A1 (en) 2005-03-21
RU2007108896A (ru) 2008-09-20
NZ544079A (en) 2007-10-26
ZA200401108B (en) 2006-05-31
CA2452417A1 (en) 2003-01-23
PT1478659E (pt) 2009-01-02
IL184227A (en) 2010-06-16
ATE414099T1 (de) 2008-11-15
EP1947109A2 (en) 2008-07-23
AU2002319423B2 (en) 2008-02-14
EP1478659B1 (en) 2008-11-12
HK1098767A1 (en) 2007-07-27
EP1790655A3 (en) 2007-10-10
RU2425053C2 (ru) 2011-07-27
DK1790655T3 (da) 2010-08-23
RU2305107C2 (ru) 2007-08-27
EP1478659A2 (en) 2004-11-24
KR20040019058A (ko) 2004-03-04
KR100889993B1 (ko) 2009-03-25
SG185137A1 (en) 2012-11-29
IL184227A0 (en) 2007-10-31
DK1478659T3 (da) 2009-01-05
JP2004533846A (ja) 2004-11-11
SG142165A1 (en) 2008-05-28
JP2008263993A (ja) 2008-11-06
JP2007312785A (ja) 2007-12-06
MXPA03011190A (es) 2004-10-28
MY138219A (en) 2009-05-29
NO20040134L (no) 2004-03-10
ZA200509838B (en) 2007-11-28
IL159827A0 (en) 2004-06-20
ES2316586T3 (es) 2009-04-16
NZ553507A (en) 2008-07-31
PT1790655E (pt) 2010-07-09
NZ529879A (en) 2007-12-21

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