ZA200308525B - Aromatic sulfone hydroxamates and their use of protease inhibitors. - Google Patents

Aromatic sulfone hydroxamates and their use of protease inhibitors. Download PDF

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Publication number
ZA200308525B
ZA200308525B ZA200308525A ZA200308525A ZA200308525B ZA 200308525 B ZA200308525 B ZA 200308525B ZA 200308525 A ZA200308525 A ZA 200308525A ZA 200308525 A ZA200308525 A ZA 200308525A ZA 200308525 B ZA200308525 B ZA 200308525B
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South Africa
Prior art keywords
alkyl
alkoxy
group
substituted
halogen
Prior art date
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ZA200308525A
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English (en)
Inventor
Thomas E Barta
Daniel P Becker
Louis J Bedell
Terri L Boehm
Jeffery N Carroll
Gary A De Crescenzo
Yvette M Fobian
John N Freskos
Susan L Hockerman
Darren J Kassab
Stephen A Kolodziej
Joseph J Mcdonald
Deborah A Mischke
Monica Norton
Joseph G Rico
John Jeffrey Talley
Clara I Villamil
Lijuan Jane Wang
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Pharmacia Corp
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Publication of ZA200308525B publication Critical patent/ZA200308525B/en

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    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
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    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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ZA200308525A 2001-05-11 2003-01-31 Aromatic sulfone hydroxamates and their use of protease inhibitors. ZA200308525B (en)

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AR040928A1 (es) 2005-04-27
WO2002092588A2 (en) 2002-11-21
US20040010019A1 (en) 2004-01-15
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US6890928B2 (en) 2005-05-10
US6689794B2 (en) 2004-02-10
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NO20034995D0 (no) 2003-11-10
KR20040018368A (ko) 2004-03-03
ECSP034839A (es) 2003-12-24
US20040110805A1 (en) 2004-06-10
US20050101641A1 (en) 2005-05-12
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CZ20032913A3 (cs) 2004-05-12
CA2446586A1 (en) 2002-11-21
IL158454A0 (en) 2004-05-12
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BR0209525A (pt) 2004-03-09
HRP20030901A2 (en) 2005-10-31
AP2003002908A0 (en) 2003-12-31
PL367487A1 (en) 2005-02-21
MXPA03010326A (es) 2004-07-30
CR7146A (es) 2008-02-11
IS7003A (is) 2003-10-29
EP1385836A2 (en) 2004-02-04
YU85403A (sh) 2006-03-03

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