ZA200306432B - Bipiperidinyl-derivatives and their use as chemokine receptors inhibitors. - Google Patents
Bipiperidinyl-derivatives and their use as chemokine receptors inhibitors. Download PDFInfo
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- ZA200306432B ZA200306432B ZA200306432A ZA200306432A ZA200306432B ZA 200306432 B ZA200306432 B ZA 200306432B ZA 200306432 A ZA200306432 A ZA 200306432A ZA 200306432 A ZA200306432 A ZA 200306432A ZA 200306432 B ZA200306432 B ZA 200306432B
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- South Africa
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- phenyl
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Classifications
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- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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Landscapes
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| GBGB0108876.4A GB0108876D0 (en) | 2001-04-09 | 2001-04-09 | Organic Compounds |
Publications (1)
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| ZA200306432B true ZA200306432B (en) | 2004-06-04 |
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| CN (1) | CN100469767C (es) |
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| CA2452597A1 (en) | 2001-07-02 | 2003-01-16 | Astrazeneca Ab | Piperidine derivatives useful as modulators of chemokine receptor activity |
| GB0120461D0 (en) | 2001-08-22 | 2001-10-17 | Astrazeneca Ab | Novel compounds |
| AR036366A1 (es) | 2001-08-29 | 2004-09-01 | Schering Corp | Derivados de piperidina utiles como antagonistas de ccr5, composiciones farmaceuticas, el uso de dichos derivados para la fabricación de un medicamento y un kit |
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| SE0202838D0 (sv) * | 2002-09-24 | 2002-09-24 | Astrazeneca Ab | Chemical compounds |
| SI1556045T1 (sl) * | 2002-10-04 | 2007-02-28 | Ucb Sa | Derivati 4-aminopiperidina, postopek izdelave in uporaba v medicini |
| GB0223223D0 (en) * | 2002-10-07 | 2002-11-13 | Novartis Ag | Organic compounds |
| US7452992B2 (en) | 2002-12-13 | 2008-11-18 | Smithkline Beecham Corporation | Heterocyclic compounds as CCR5 antagonists |
| SE0300957D0 (sv) | 2003-04-01 | 2003-04-01 | Astrazeneca Ab | Chemical compounds |
| US20070043079A1 (en) * | 2003-04-18 | 2007-02-22 | Hiromu Habashita | Heterocyclic compound containing nitrogen atom and use thereof |
| FR2854158B1 (fr) | 2003-04-25 | 2006-11-17 | Sanofi Synthelabo | Derives de 2-acylamino-4-phenylethiazole, leur preparation et leur application en therapeutique |
| MXPA05013474A (es) * | 2003-06-13 | 2006-03-09 | Schering Ag | Derivados de quinolilamida como antagonistas de ccr-5. |
| CN1898231B (zh) | 2003-11-03 | 2010-10-27 | 先灵公司 | 用作趋化因子受体抑制剂的双六氢吡啶衍生物 |
| US7498346B2 (en) * | 2003-12-11 | 2009-03-03 | Genzyme Corporation | Chemokine receptor binding compounds |
| US7381738B2 (en) | 2004-02-19 | 2008-06-03 | Bristol-Myers Squibb Company | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity |
| US7288563B2 (en) | 2004-02-19 | 2007-10-30 | Bristol-Myers Squibb Company | Substituted bicycloalkylamine derivatives as modulators of chemokine receptor activity |
| US7479496B2 (en) | 2004-02-19 | 2009-01-20 | Bristol-Myers Squibb Company | Substituted spiro azabicyclics as modulators of chemokine receptor activity |
| US7230022B2 (en) | 2004-02-19 | 2007-06-12 | Bristol-Myers Squibb Company | Substituted fused bicyclic amines as modulators of chemokine receptor activity |
| EP1844037A1 (en) * | 2005-01-20 | 2007-10-17 | Pfizer Limited | Chemical compounds |
| AU2006270548A1 (en) | 2005-07-21 | 2007-01-25 | Astrazeneca Ab | Novel piperidine derivatives |
| US20080108586A1 (en) * | 2006-09-06 | 2008-05-08 | Incyte Corporation | Combination therapy for human immunodeficiency virus infection |
| EP2088860A4 (en) * | 2006-12-06 | 2010-12-22 | Genzyme Corp | COMPOUNDS FOR BINDING TO A CHEMOKINE RECEPTOR |
| CA2756870A1 (en) | 2009-03-31 | 2010-10-07 | Arqule, Inc. | Substituted indolo-pyridinone compounds |
| WO2012122499A2 (en) | 2011-03-09 | 2012-09-13 | Pestell Richard G | Prostate cancer cell lines, gene signatures and uses thereof |
| WO2013173312A1 (en) * | 2012-05-14 | 2013-11-21 | Pestell Richard G | Using modulators of ccr5 for treating cancer |
| MX2016008114A (es) | 2013-12-19 | 2017-01-20 | Bayer Pharma AG | Piperidiniltetrahidroquinolinas sustituidas. |
| US20160318866A1 (en) | 2013-12-19 | 2016-11-03 | Bayer Pharma Aktiengesellschaft | Substituted bipiperidinyl derivatives |
| CA2934134A1 (en) | 2013-12-19 | 2015-06-25 | Bayer Pharma Aktiengesellschaft | Substituted bipiperidinyl derivatives as adrenoreceptor alpha 2c antagonists |
| JOP20200052A1 (ar) | 2013-12-19 | 2017-06-16 | Bayer Pharma AG | بيبريدينيل تتراهيدرو كوينولينات مستبدلة واستخدامها كمعضدات مستقبل أدريني ألفا- 2c |
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| US5952349A (en) * | 1996-07-10 | 1999-09-14 | Schering Corporation | Muscarinic antagonists for treating memory loss |
| ID21045A (id) * | 1996-09-10 | 1999-04-08 | Thomae Gmbh Dr K | Asam amino termodifikasi, obat-obatan yang mengandung senyawa ini dan proses pembuatannya |
| DE19637043A1 (de) * | 1996-09-12 | 1998-03-19 | Boehringer Mannheim Gmbh | Neue Aminoalkoholderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel und Reagenzien |
| DE19643331A1 (de) * | 1996-10-21 | 1998-04-23 | Thomae Gmbh Dr K | 1-(4-Piperidinyl)-piperidinylene, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung |
| US6391865B1 (en) * | 1999-05-04 | 2002-05-21 | Schering Corporation | Piperazine derivatives useful as CCR5 antagonists |
| DE60021371T2 (de) * | 1999-05-04 | 2006-04-27 | Schering Corp. | Piperidinderivate verwendbar als ccr5 antagonisten |
| EP1192133B1 (en) * | 1999-06-11 | 2006-11-02 | Merck & Co., Inc. | N-cyclopentyl modulators of chemokine receptor activity |
| CA2413418A1 (en) * | 2000-06-21 | 2001-12-27 | Joseph B. Santella | Piperidine amides as modulators of chemokine receptor activity |
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- 2002-04-08 CN CNB028079507A patent/CN100469767C/zh not_active Expired - Fee Related
- 2002-04-08 ES ES02730122T patent/ES2335393T3/es not_active Expired - Lifetime
- 2002-04-08 RU RU2003130642/04A patent/RU2296751C2/ru not_active IP Right Cessation
- 2002-04-08 PL PL02363011A patent/PL363011A1/xx not_active Application Discontinuation
- 2002-04-08 JP JP2002579437A patent/JP4366079B2/ja not_active Expired - Fee Related
- 2002-04-08 EP EP02730122A patent/EP1379504B1/en not_active Expired - Lifetime
- 2002-04-08 CZ CZ20032723A patent/CZ20032723A3/cs unknown
- 2002-04-08 WO PCT/EP2002/003871 patent/WO2002081449A1/en not_active Application Discontinuation
- 2002-04-08 BR BR0208741-3A patent/BR0208741A/pt not_active IP Right Cessation
- 2002-04-08 PT PT02730122T patent/PT1379504E/pt unknown
-
2003
- 2003-08-19 ZA ZA200306432A patent/ZA200306432B/en unknown
- 2003-09-11 EC EC2003004765A patent/ECSP034765A/es unknown
- 2003-09-26 NO NO20034324A patent/NO20034324D0/no not_active Application Discontinuation
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