ZA200303636B - Use of rosuvastatin (ZD-4522) in the treatment of heterozygous familial hypercholesterolemia. - Google Patents

Use of rosuvastatin (ZD-4522) in the treatment of heterozygous familial hypercholesterolemia. Download PDF

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Publication number
ZA200303636B
ZA200303636B ZA200303636A ZA200303636A ZA200303636B ZA 200303636 B ZA200303636 B ZA 200303636B ZA 200303636 A ZA200303636 A ZA 200303636A ZA 200303636 A ZA200303636 A ZA 200303636A ZA 200303636 B ZA200303636 B ZA 200303636B
Authority
ZA
South Africa
Prior art keywords
patient
treatment
substance
composition
dihydroxyhept
Prior art date
Application number
ZA200303636A
Other languages
English (en)
Inventor
Ali Raza
Howard Gerard Hutchinson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9903629&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200303636(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ZA200303636B publication Critical patent/ZA200303636B/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200303636A 2000-11-22 2003-05-12 Use of rosuvastatin (ZD-4522) in the treatment of heterozygous familial hypercholesterolemia. ZA200303636B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0028429.9A GB0028429D0 (en) 2000-11-22 2000-11-22 Therapy

Publications (1)

Publication Number Publication Date
ZA200303636B true ZA200303636B (en) 2004-08-12

Family

ID=9903629

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200303636A ZA200303636B (en) 2000-11-22 2003-05-12 Use of rosuvastatin (ZD-4522) in the treatment of heterozygous familial hypercholesterolemia.

Country Status (35)

Country Link
US (1) US6858618B2 (de)
EP (1) EP1339409B1 (de)
JP (2) JP5062940B2 (de)
KR (1) KR100815042B1 (de)
CN (1) CN1268339C (de)
AR (1) AR031766A1 (de)
AT (1) ATE394103T1 (de)
AU (2) AU2002214165B9 (de)
BG (1) BG66009B1 (de)
BR (1) BR0115511A (de)
CA (1) CA2429263C (de)
CY (1) CY1110428T1 (de)
CZ (1) CZ301583B6 (de)
DE (1) DE60133921D1 (de)
DK (1) DK1339409T3 (de)
EE (1) EE05507B1 (de)
ES (1) ES2305118T3 (de)
GB (1) GB0028429D0 (de)
HK (1) HK1056691A1 (de)
HU (1) HUP0301380A3 (de)
IL (2) IL155919A0 (de)
IS (1) IS6819A (de)
MX (1) MXPA03004336A (de)
MY (1) MY134902A (de)
NO (1) NO326245B1 (de)
NZ (1) NZ525754A (de)
PL (1) PL365386A1 (de)
PT (1) PT1339409E (de)
RU (1) RU2294744C2 (de)
SI (1) SI1339409T1 (de)
SK (1) SK6212003A3 (de)
TW (1) TWI238720B (de)
UA (1) UA75614C2 (de)
WO (1) WO2002041895A1 (de)
ZA (1) ZA200303636B (de)

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GB0003305D0 (en) 2000-02-15 2000-04-05 Zeneca Ltd Pyrimidine derivatives
MXPA05011296A (es) * 2003-04-25 2006-01-24 Gilead Sciences Inc Conjugados de fosfonato inhibidores de la cinasa.
US7452901B2 (en) * 2003-04-25 2008-11-18 Gilead Sciences, Inc. Anti-cancer phosphonate analogs
US20050261237A1 (en) * 2003-04-25 2005-11-24 Boojamra Constantine G Nucleoside phosphonate analogs
US7407965B2 (en) * 2003-04-25 2008-08-05 Gilead Sciences, Inc. Phosphonate analogs for treating metabolic diseases
US20090247488A1 (en) * 2003-04-25 2009-10-01 Carina Cannizzaro Anti-inflammatory phosphonate compounds
ATE490788T1 (de) 2003-04-25 2010-12-15 Gilead Sciences Inc Antivirale phosphonate analoge
US7470724B2 (en) * 2003-04-25 2008-12-30 Gilead Sciences, Inc. Phosphonate compounds having immuno-modulatory activity
WO2005023778A2 (en) * 2003-08-28 2005-03-17 Teva Pharmaceutical Industries Ltd. Process for preparation of rosuvastatin calcium
GB0322552D0 (en) 2003-09-26 2003-10-29 Astrazeneca Uk Ltd Therapeutic treatment
WO2005044308A1 (en) * 2003-10-24 2005-05-19 Gilead Sciences, Inc. Phosphonate analogs of antimetabolites
TW200526596A (en) 2003-11-24 2005-08-16 Teva Pharma Crystalline ammonium salts of rosuvastatin
EP1689723B1 (de) * 2003-12-02 2011-04-27 Teva Pharmaceutical Industries, Ltd. Referenzstandard zur charakterisierung von rosuvastatin
US7851624B2 (en) * 2003-12-24 2010-12-14 Teva Pharamaceutical Industries Ltd. Triol form of rosuvastatin and synthesis of rosuvastatin
US20070179166A1 (en) * 2003-12-24 2007-08-02 Valerie Niddam-Hildesheim Process for preparation of statins with high syn to anti ratio
WO2005115377A1 (en) * 2004-05-26 2005-12-08 Kgk Synergize Inc Functional foods comprising flavonoids and tocotrienols and methods thereof
WO2006017357A1 (en) * 2004-07-13 2006-02-16 Teva Pharmaceutical Industries Ltd. A process for the preparation of rosuvastatin involving a tempo-mediated oxidation step
ES2720618T3 (es) 2004-07-27 2019-07-23 Gilead Sciences Inc Análogos de fosfonato de compuestos de inhibidores de VIH
WO2006091771A2 (en) * 2005-02-22 2006-08-31 Teva Pharmaceutical Industries Ltd. Preparation of rosuvastatin
US20070037979A1 (en) * 2005-02-22 2007-02-15 Valerie Niddam-Hildesheim Preparation of rosuvastatin
US20070167625A1 (en) * 2005-02-22 2007-07-19 Anna Balanov Preparation of rosuvastatin
WO2007022488A2 (en) * 2005-08-16 2007-02-22 Teva Pharmaceutical Industries Ltd. Crystalline rosuvastatin intermediate
US8383614B2 (en) * 2008-01-31 2013-02-26 The Trustees Of The University Of Pennsylvania Hypercholestrolemia and tendinous injuries
US9427437B2 (en) 2008-01-31 2016-08-30 The Trustees Of The University Of Pennsylvania Hypercholesterolemia and tendinous injuries
EP2298745B1 (de) 2008-05-27 2014-09-03 Changzhou Pharmaceutical Factory Verfahren zur herstellung von rosuvastatin-calcium und dessen zwischenprodukten
UA103329C2 (ru) 2008-07-08 2013-10-10 Гилиад Сайенсиз, Инк. Соли соединений-ингибиторов вич
RU2018128393A (ru) 2012-09-17 2019-03-14 Мадригал Фармасьютикалз, Инк. Способ синтеза аналогов гормонов щитовидной железы и их полиморфов
US9132117B2 (en) 2013-06-17 2015-09-15 Kgk Synergize, Inc Compositions and methods for glycemic control of subjects with impaired fasting glucose
US10600502B2 (en) 2016-12-20 2020-03-24 Astrazeneca Uk Ltd. Systems and methods for dispensing a statin medication over the counter
PL3661937T3 (pl) 2017-08-01 2021-12-20 Gilead Sciences, Inc. Formy krystaliczne ((s)-((((2r,5r)-5-(6-amino-9h-puryn-9-ylo)-4-fluoro-2,5-dihydrofuran-2-ylo)oksy)metylo)(fenoksy)fosforylo)-l-alaninianu etylu (gs-9131) do leczenia zakażeń wirusowych
MX2021014552A (es) 2019-05-27 2022-02-11 Immatics Us Inc Vectores viricos y uso de los mismos en terapias celulares adoptivas.
DE102020111571A1 (de) 2020-03-11 2021-09-16 Immatics US, Inc. Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
US20220008519A1 (en) 2020-07-09 2022-01-13 Costa Rican Social Security Fund / Caja Costarricense de Seguro Social (CCSS) Treatment of severe acute respiratory syndrome-related coronavirus infection with klotho
US20220056411A1 (en) 2020-08-21 2022-02-24 Immatics US, Inc. Methods for isolating cd8+ selected t cells
TW202245775A (zh) * 2021-02-01 2022-12-01 美商瑪德瑞高製藥公司 用於治療肝病症或脂質病症之瑞舒伐他汀(Rosuvastatin)和瑞司美替隆(Resmetirom)的治療組合

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2648897B2 (ja) * 1991-07-01 1997-09-03 塩野義製薬株式会社 ピリミジン誘導体
US6369103B1 (en) * 1994-01-18 2002-04-09 Bristol-Myers Squibb Company Method for preventing or reducing risk of onset of cardiovascular events employing an HMG CoA reductase inhibitor
GB0001621D0 (en) * 2000-01-26 2000-03-15 Astrazeneca Ab Pharmaceutical compositions
ATE367802T1 (de) * 2000-09-20 2007-08-15 Jagotec Ag Verfahren zur sprühtrocknung von zusammensetzungen enthaltend fenofibrat

Also Published As

Publication number Publication date
EE200300239A (et) 2003-08-15
HUP0301380A3 (en) 2007-03-28
CY1110428T1 (el) 2015-04-29
CZ301583B6 (cs) 2010-04-21
EP1339409A1 (de) 2003-09-03
AU2002214165B9 (en) 2013-07-04
UA75614C2 (uk) 2006-05-15
PL365386A1 (en) 2005-01-10
SI1339409T1 (sl) 2008-08-31
IS6819A (is) 2003-05-19
BG107811A (bg) 2004-03-31
PT1339409E (pt) 2008-07-07
KR100815042B1 (ko) 2008-03-18
GB0028429D0 (en) 2001-01-10
BG66009B1 (bg) 2010-10-29
IL155919A (en) 2009-09-01
ES2305118T3 (es) 2008-11-01
DK1339409T3 (da) 2008-09-08
EE05507B1 (et) 2012-02-15
CN1268339C (zh) 2006-08-09
AU1416502A (en) 2002-06-03
US20040072852A1 (en) 2004-04-15
CA2429263A1 (en) 2002-05-30
HK1056691A1 (en) 2004-02-27
JP2010031047A (ja) 2010-02-12
CA2429263C (en) 2009-03-17
MY134902A (en) 2007-12-31
JP5062940B2 (ja) 2012-10-31
IL155919A0 (en) 2003-12-23
NO20032292L (no) 2003-07-17
WO2002041895A1 (en) 2002-05-30
NZ525754A (en) 2004-10-29
DE60133921D1 (de) 2008-06-19
AR031766A1 (es) 2003-10-01
BR0115511A (pt) 2003-12-30
ATE394103T1 (de) 2008-05-15
MXPA03004336A (es) 2003-08-19
CZ20031406A3 (cs) 2003-09-17
EP1339409B1 (de) 2008-05-07
RU2294744C2 (ru) 2007-03-10
SK6212003A3 (en) 2003-11-04
JP2004522714A (ja) 2004-07-29
TWI238720B (en) 2005-09-01
HUP0301380A2 (hu) 2003-10-28
CN1630520A (zh) 2005-06-22
KR20030048479A (ko) 2003-06-19
AU2002214165B2 (en) 2006-12-14
US6858618B2 (en) 2005-02-22
NO20032292D0 (no) 2003-05-21
NO326245B1 (no) 2008-10-27

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