ZA200302321B - A novel strain of Streptomyces for controlling plant diseases. - Google Patents
A novel strain of Streptomyces for controlling plant diseases. Download PDFInfo
- Publication number
- ZA200302321B ZA200302321B ZA200302321A ZA200302321A ZA200302321B ZA 200302321 B ZA200302321 B ZA 200302321B ZA 200302321 A ZA200302321 A ZA 200302321A ZA 200302321 A ZA200302321 A ZA 200302321A ZA 200302321 B ZA200302321 B ZA 200302321B
- Authority
- ZA
- South Africa
- Prior art keywords
- strain
- metabolite
- streptomyces
- composition
- daltons
- Prior art date
Links
- 241000187747 Streptomyces Species 0.000 title abstract description 10
- 201000010099 disease Diseases 0.000 title description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title description 11
- 239000002207 metabolite Substances 0.000 claims abstract description 47
- 238000000034 method Methods 0.000 claims abstract description 34
- 239000000203 mixture Substances 0.000 claims abstract description 30
- 241000187180 Streptomyces sp. Species 0.000 claims abstract description 23
- 239000000126 substance Substances 0.000 claims abstract description 18
- 239000000575 pesticide Substances 0.000 claims abstract description 9
- 208000031888 Mycoses Diseases 0.000 claims abstract description 8
- 206010017533 Fungal infection Diseases 0.000 claims abstract description 6
- 230000000694 effects Effects 0.000 claims description 22
- 238000009631 Broth culture Methods 0.000 claims description 12
- 241000233866 Fungi Species 0.000 claims description 12
- 238000009472 formulation Methods 0.000 claims description 7
- 239000006228 supernatant Substances 0.000 claims description 7
- 241000123650 Botrytis cinerea Species 0.000 claims description 6
- 235000013399 edible fruits Nutrition 0.000 claims description 5
- 241000213004 Alternaria solani Species 0.000 claims description 4
- 241000684075 Rhizoctonia sp. Species 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 4
- 125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 claims description 4
- 244000000004 fungal plant pathogen Species 0.000 claims description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 2
- 241000031556 Phytophthora sp. Species 0.000 claims description 2
- 241000966613 Sclerotinia sp. Species 0.000 claims description 2
- 239000007900 aqueous suspension Substances 0.000 claims description 2
- 239000004495 emulsifiable concentrate Substances 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 239000004563 wettable powder Substances 0.000 claims 1
- 230000000843 anti-fungal effect Effects 0.000 abstract description 19
- 230000003115 biocidal effect Effects 0.000 abstract description 19
- 239000003242 anti bacterial agent Substances 0.000 abstract description 13
- 244000000003 plant pathogen Species 0.000 abstract description 13
- 229940088710 antibiotic agent Drugs 0.000 abstract description 9
- 230000000855 fungicidal effect Effects 0.000 abstract description 6
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 63
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 60
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 46
- 238000004128 high performance liquid chromatography Methods 0.000 description 22
- 239000002904 solvent Substances 0.000 description 22
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 18
- 244000052769 pathogen Species 0.000 description 17
- 230000035784 germination Effects 0.000 description 15
- 230000001717 pathogenic effect Effects 0.000 description 15
- 241000196324 Embryophyta Species 0.000 description 14
- 150000001875 compounds Chemical class 0.000 description 14
- 229920001817 Agar Polymers 0.000 description 12
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 description 12
- 239000008272 agar Substances 0.000 description 12
- 238000003556 assay Methods 0.000 description 12
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 10
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 9
- 240000003768 Solanum lycopersicum Species 0.000 description 9
- 238000000855 fermentation Methods 0.000 description 9
- 230000004151 fermentation Effects 0.000 description 9
- 229940121375 antifungal agent Drugs 0.000 description 8
- 238000000746 purification Methods 0.000 description 8
- 241001468228 Streptomyces mashuensis Species 0.000 description 7
- 238000004166 bioassay Methods 0.000 description 7
- 244000005700 microbiome Species 0.000 description 7
- 239000000725 suspension Substances 0.000 description 7
- 238000011282 treatment Methods 0.000 description 7
- 238000002211 ultraviolet spectrum Methods 0.000 description 7
- 241001157812 Alternaria brassicicola Species 0.000 description 5
- 241000233622 Phytophthora infestans Species 0.000 description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 5
- 238000000338 in vitro Methods 0.000 description 5
- 230000000361 pesticidal effect Effects 0.000 description 5
- 239000002952 polymeric resin Substances 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 229920003002 synthetic resin Polymers 0.000 description 5
- 108020004465 16S ribosomal RNA Proteins 0.000 description 4
- 241000223600 Alternaria Species 0.000 description 4
- 235000017060 Arachis glabrata Nutrition 0.000 description 4
- 244000105624 Arachis hypogaea Species 0.000 description 4
- 235000010777 Arachis hypogaea Nutrition 0.000 description 4
- 235000018262 Arachis monticola Nutrition 0.000 description 4
- 241001518731 Monilinia fructicola Species 0.000 description 4
- 230000001580 bacterial effect Effects 0.000 description 4
- 238000009792 diffusion process Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 239000002609 medium Substances 0.000 description 4
- 235000020232 peanut Nutrition 0.000 description 4
- 238000012163 sequencing technique Methods 0.000 description 4
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 4
- UHPMCKVQTMMPCG-UHFFFAOYSA-N 5,8-dihydroxy-2-methoxy-6-methyl-7-(2-oxopropyl)naphthalene-1,4-dione Chemical compound CC1=C(CC(C)=O)C(O)=C2C(=O)C(OC)=CC(=O)C2=C1O UHPMCKVQTMMPCG-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- 241000223218 Fusarium Species 0.000 description 3
- 101710084218 Master replication protein Proteins 0.000 description 3
- 101000708578 Milk vetch dwarf virus (isolate N) Para-Rep C3 Proteins 0.000 description 3
- 101710112078 Para-Rep C2 Proteins 0.000 description 3
- 241000233639 Pythium Species 0.000 description 3
- 241001361634 Rhizoctonia Species 0.000 description 3
- 241000813090 Rhizoctonia solani Species 0.000 description 3
- 230000002745 absorbent Effects 0.000 description 3
- 239000002250 absorbent Substances 0.000 description 3
- 230000003321 amplification Effects 0.000 description 3
- 230000008485 antagonism Effects 0.000 description 3
- 230000001276 controlling effect Effects 0.000 description 3
- 238000010790 dilution Methods 0.000 description 3
- 239000012895 dilution Substances 0.000 description 3
- 230000001747 exhibiting effect Effects 0.000 description 3
- 230000002538 fungal effect Effects 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 238000011068 loading method Methods 0.000 description 3
- 238000003199 nucleic acid amplification method Methods 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- 239000001965 potato dextrose agar Substances 0.000 description 3
- 230000010076 replication Effects 0.000 description 3
- 239000000741 silica gel Substances 0.000 description 3
- 229910002027 silica gel Inorganic materials 0.000 description 3
- 239000002689 soil Substances 0.000 description 3
- 241000894007 species Species 0.000 description 3
- BTUZNIQVZBANAX-SWQYCTROSA-N (13Z,17Z,21Z,29Z)-48-(8-aminooctan-2-yl)-8,10,16,20,24,26,28,32,36,38,40,42,44,46-tetradecahydroxy-9,15,17,19,21,25,31,33,39,41,47-undecamethyl-23-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1-oxacyclooctatetraconta-13,17,21,29-tetraen-2-one Chemical compound CC1CCC(CC(C(C(C(C(CC(CC(C(C(OC(=O)CCCCCC(C(C(CC/C=C\C(C(/C(=C\C(C(/C(=C\C(C(C(C(CC(/C=C\C(C1O)C)O)O)C)O)O[C@@H]2[C@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)/C)O)C)/C)O)C)O)C)O)C(C)CCCCCCN)C)O)O)O)C)O)C)O)O BTUZNIQVZBANAX-SWQYCTROSA-N 0.000 description 2
- 241000186361 Actinobacteria <class> Species 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 2
- 235000014466 Douglas bleu Nutrition 0.000 description 2
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 description 2
- 238000005481 NMR spectroscopy Methods 0.000 description 2
- 241000233616 Phytophthora capsici Species 0.000 description 2
- 240000001416 Pseudotsuga menziesii Species 0.000 description 2
- 235000005386 Pseudotsuga menziesii var menziesii Nutrition 0.000 description 2
- 238000003559 RNA-seq method Methods 0.000 description 2
- 241000221662 Sclerotinia Species 0.000 description 2
- 241001518705 Sclerotinia minor Species 0.000 description 2
- 241000810757 Streptomyces geldanamycininus Species 0.000 description 2
- 241000187391 Streptomyces hygroscopicus Species 0.000 description 2
- 241001655322 Streptomycetales Species 0.000 description 2
- 238000012459 agar diffusion assay Methods 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- WFDXOXNFNRHQEC-GHRIWEEISA-N azoxystrobin Chemical compound CO\C=C(\C(=O)OC)C1=CC=CC=C1OC1=CC(OC=2C(=CC=CC=2)C#N)=NC=N1 WFDXOXNFNRHQEC-GHRIWEEISA-N 0.000 description 2
- 239000012681 biocontrol agent Substances 0.000 description 2
- 230000000853 biopesticidal effect Effects 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 238000012512 characterization method Methods 0.000 description 2
- 239000000356 contaminant Substances 0.000 description 2
- YPHMISFOHDHNIV-FSZOTQKASA-N cycloheximide Chemical compound C1[C@@H](C)C[C@H](C)C(=O)[C@@H]1[C@H](O)CC1CC(=O)NC(=O)C1 YPHMISFOHDHNIV-FSZOTQKASA-N 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 239000003480 eluent Substances 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 238000000099 in vitro assay Methods 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 238000004811 liquid chromatography Methods 0.000 description 2
- 238000004895 liquid chromatography mass spectrometry Methods 0.000 description 2
- 238000001972 liquid chromatography-electrospray ionisation mass spectrometry Methods 0.000 description 2
- 238000001819 mass spectrum Methods 0.000 description 2
- 239000013642 negative control Substances 0.000 description 2
- 239000013641 positive control Substances 0.000 description 2
- TVDSBUOJIPERQY-UHFFFAOYSA-N prop-2-yn-1-ol Chemical compound OCC#C TVDSBUOJIPERQY-UHFFFAOYSA-N 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 238000004007 reversed phase HPLC Methods 0.000 description 2
- 238000007790 scraping Methods 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 230000004763 spore germination Effects 0.000 description 2
- 229960005322 streptomycin Drugs 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 108700012359 toxins Proteins 0.000 description 2
- 229930188428 trichomycin Natural products 0.000 description 2
- 238000000825 ultraviolet detection Methods 0.000 description 2
- RZLRMVZBGPHYJA-XXJPCBNGSA-N (1s,2e,5s,8s,9s,10e,14r,15r,16s)-5-hydroxy-15-[[(2r,3r,4r,5r,6r)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-8-[(2s,3r,4s,6r)-3-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5,9,14-trimethyl-13,17-dioxabicyclo[14.1.0]heptadeca-2,10-diene-4,12-dione Chemical compound O[C@@H]1[C@@H](OC)C[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)/C=C/C(=O)O[C@H](C)[C@@H](CO[C@H]2[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O2)OC)[C@@H]2O[C@H]2/C=C/C(=O)[C@@](C)(O)CC1 RZLRMVZBGPHYJA-XXJPCBNGSA-N 0.000 description 1
- ZGEGCLOFRBLKSE-UHFFFAOYSA-N 1-Heptene Chemical class CCCCCC=C ZGEGCLOFRBLKSE-UHFFFAOYSA-N 0.000 description 1
- 125000001494 2-propynyl group Chemical group [H]C#CC([H])([H])* 0.000 description 1
- 238000005084 2D-nuclear magnetic resonance Methods 0.000 description 1
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- 241000212251 Alternaria dauci Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 231100000699 Bacterial toxin Toxicity 0.000 description 1
- 241001465180 Botrytis Species 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 241001123536 Colletotrichum acutatum Species 0.000 description 1
- 241000723247 Cylindrocarpon Species 0.000 description 1
- RZLRMVZBGPHYJA-UHFFFAOYSA-N Cynanformoside B Natural products OC1C(OC)CC(C)OC1OC1C(C)C=CC(=O)OC(C)C(COC2C(C(OC)C(O)C(C)O2)OC)C2OC2C=CC(=O)C(C)(O)CC1 RZLRMVZBGPHYJA-UHFFFAOYSA-N 0.000 description 1
- 238000010442 DNA editing Methods 0.000 description 1
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 description 1
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- JRZJKWGQFNTSRN-UHFFFAOYSA-N Geldanamycin Natural products C1C(C)CC(OC)C(O)C(C)C=C(C)C(OC(N)=O)C(OC)CCC=C(C)C(=O)NC2=CC(=O)C(OC)=C1C2=O JRZJKWGQFNTSRN-UHFFFAOYSA-N 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 241000970986 Kitasatospora herbaricolor Species 0.000 description 1
- HRHKSTOGXBBQCB-UHFFFAOYSA-N Mitomycin E Natural products O=C1C(N)=C(C)C(=O)C2=C1C(COC(N)=O)C1(OC)C3N(C)C3CN12 HRHKSTOGXBBQCB-UHFFFAOYSA-N 0.000 description 1
- NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical class C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 description 1
- VZUNGTLZRAYYDE-UHFFFAOYSA-N N-methyl-N'-nitro-N-nitrosoguanidine Chemical compound O=NN(C)C(=N)N[N+]([O-])=O VZUNGTLZRAYYDE-UHFFFAOYSA-N 0.000 description 1
- VXVAFQMBYKUOIZ-UHFFFAOYSA-N Neutramycin Natural products COC(=O)C=CC#CC#CCO VXVAFQMBYKUOIZ-UHFFFAOYSA-N 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- -1 Phenyl-Hexyl Chemical group 0.000 description 1
- 241000233614 Phytophthora Species 0.000 description 1
- 241000233629 Phytophthora parasitica Species 0.000 description 1
- 241000948155 Phytophthora sojae Species 0.000 description 1
- 235000016761 Piper aduncum Nutrition 0.000 description 1
- 235000017804 Piper guineense Nutrition 0.000 description 1
- 244000203593 Piper nigrum Species 0.000 description 1
- 235000008184 Piper nigrum Nutrition 0.000 description 1
- 241000221535 Pucciniales Species 0.000 description 1
- 241001385948 Pythium sp. Species 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 241000221696 Sclerotinia sclerotiorum Species 0.000 description 1
- 229920005654 Sephadex Polymers 0.000 description 1
- 239000012507 Sephadex™ Substances 0.000 description 1
- 239000005838 Streptomyces K61 (formerly S. griseoviridis) Substances 0.000 description 1
- 241000187758 Streptomyces ambofaciens Species 0.000 description 1
- 241000936803 Streptomyces coeruleofuscus Species 0.000 description 1
- 241000499056 Streptomyces griseocarneus Species 0.000 description 1
- 241000191251 Streptomyces griseoviridis Species 0.000 description 1
- 239000005865 Streptomyces lydicus WYEC 108 Substances 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 108020004566 Transfer RNA Proteins 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- KIPLYOUQVMMOHB-MXWBXKMOSA-L [Ca++].CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C([O-])[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c1c(O)cccc1[C@@]3(C)O.CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C([O-])[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c1c(O)cccc1[C@@]3(C)O Chemical compound [Ca++].CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C([O-])[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c1c(O)cccc1[C@@]3(C)O.CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C([O-])[C@]2(O)C(=O)C(C(N)=O)=C1O)C(=O)c1c(O)cccc1[C@@]3(C)O KIPLYOUQVMMOHB-MXWBXKMOSA-L 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- PBCJIPOGFJYBJE-UHFFFAOYSA-N acetonitrile;hydrate Chemical compound O.CC#N PBCJIPOGFJYBJE-UHFFFAOYSA-N 0.000 description 1
- 238000010306 acid treatment Methods 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000011543 agarose gel Substances 0.000 description 1
- 230000009418 agronomic effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000012871 anti-fungal composition Substances 0.000 description 1
- 239000012223 aqueous fraction Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 239000000688 bacterial toxin Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000002021 butanolic extract Substances 0.000 description 1
- 239000002034 butanolic fraction Substances 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 238000001460 carbon-13 nuclear magnetic resonance spectrum Methods 0.000 description 1
- 231100000357 carcinogen Toxicity 0.000 description 1
- 239000003183 carcinogenic agent Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 229930002875 chlorophyll Natural products 0.000 description 1
- 235000019804 chlorophyll Nutrition 0.000 description 1
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- QTQAWLPCGQOSGP-GBTDJJJQSA-N geldanamycin Chemical compound N1C(=O)\C(C)=C/C=C\[C@@H](OC)[C@H](OC(N)=O)\C(C)=C/[C@@H](C)[C@@H](O)[C@H](OC)C[C@@H](C)CC2=C(OC)C(=O)C=C1C2=O QTQAWLPCGQOSGP-GBTDJJJQSA-N 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000010829 isocratic elution Methods 0.000 description 1
- 238000009630 liquid culture Methods 0.000 description 1
- 230000036244 malformation Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- HRHKSTOGXBBQCB-VFWICMBZSA-N methylmitomycin Chemical compound O=C1C(N)=C(C)C(=O)C2=C1[C@@H](COC(N)=O)[C@@]1(OC)[C@H]3N(C)[C@H]3CN12 HRHKSTOGXBBQCB-VFWICMBZSA-N 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000002703 mutagenesis Methods 0.000 description 1
- 231100000350 mutagenesis Toxicity 0.000 description 1
- 229950003438 neutramycin Drugs 0.000 description 1
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
- 229960000988 nystatin Drugs 0.000 description 1
- VQOXZBDYSJBXMA-NQTDYLQESA-N nystatin A1 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 VQOXZBDYSJBXMA-NQTDYLQESA-N 0.000 description 1
- YTJSFYQNRXLOIC-UHFFFAOYSA-N octadecylsilane Chemical group CCCCCCCCCCCCCCCCCC[SiH3] YTJSFYQNRXLOIC-UHFFFAOYSA-N 0.000 description 1
- 125000002347 octyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000000238 one-dimensional nuclear magnetic resonance spectroscopy Methods 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 229950004406 porfiromycin Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 210000003705 ribosome Anatomy 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000028070 sporulation Effects 0.000 description 1
- 239000007362 sporulation medium Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 229940063650 terramycin Drugs 0.000 description 1
- WROMPOXWARCANT-UHFFFAOYSA-N tfa trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F.OC(=O)C(F)(F)F WROMPOXWARCANT-UHFFFAOYSA-N 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N61/00—Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/20—Bacteria; Substances produced thereby or obtained therefrom
- A01N63/28—Streptomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/04—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/671,943 US6524577B1 (en) | 2000-09-27 | 2000-09-27 | Strain of Streptomyces for controlling plant diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200302321B true ZA200302321B (en) | 2004-06-25 |
Family
ID=24696512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200302321A ZA200302321B (en) | 2000-09-27 | 2003-03-25 | A novel strain of Streptomyces for controlling plant diseases. |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US6524577B1 (fr) |
| EP (1) | EP1322170B1 (fr) |
| JP (1) | JP5148802B2 (fr) |
| KR (1) | KR100908635B1 (fr) |
| AT (1) | ATE292385T1 (fr) |
| AU (2) | AU9485401A (fr) |
| BR (2) | BR0114192B1 (fr) |
| CA (1) | CA2423124C (fr) |
| CR (1) | CR6933A (fr) |
| DE (1) | DE60109948T2 (fr) |
| ES (1) | ES2238483T3 (fr) |
| IL (1) | IL155087A0 (fr) |
| MX (1) | MXPA03002573A (fr) |
| NZ (1) | NZ525481A (fr) |
| TW (1) | TWI251465B (fr) |
| WO (1) | WO2002026041A2 (fr) |
| ZA (1) | ZA200302321B (fr) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7294501B2 (en) * | 2003-12-08 | 2007-11-13 | Universite De Sherbrooke | Geldanamycin-producing strains, uses thereof and methods of producing same |
| CN100497595C (zh) * | 2006-09-21 | 2009-06-10 | 广东省农业科学院植物保护研究所 | 一种土壤放线菌发酵液的提取物及其制备方法和应用 |
| KR100876431B1 (ko) | 2007-04-27 | 2008-12-29 | 임태헌 | 스트렙토마이세스 ｓｐ. ＭＧ121 균주, 및 이를 포함하는식물병 방제제 |
| US7913117B2 (en) * | 2007-08-10 | 2011-03-22 | International Business Machines Corporation | Providing removable storage management services using removable storage error information |
| US20090199473A1 (en) * | 2008-02-13 | 2009-08-13 | Watson Jr William J | Horticultural Growth Medium |
| WO2012016140A2 (fr) * | 2010-07-30 | 2012-02-02 | Bioworks, Inc. | Stimulation de la croissance et lutte contre des maladies végétales bactériennes et fongiques des plantes par streptomyces scopuliridis |
| CA2822296A1 (fr) | 2010-12-21 | 2012-06-28 | Bayer Cropscience Lp | Mutants « papier de verre » de bacillus et leurs procedes d'utilisation pour stimuler la croissance vegetale, promouvoir la sante vegetale et lutter contre des maladies et des nuisibles |
| EP2548973A1 (fr) * | 2011-07-20 | 2013-01-23 | Centre National de la Recherche Scientifique | Nouvelle composition de souche d'actinomycète et son utilisation |
| FR2980334B1 (fr) | 2011-09-26 | 2015-05-29 | Polyor Sarl | Renforecement azote d'engrais foliaires therapeutiques |
| US10681914B2 (en) | 2012-05-29 | 2020-06-16 | Neozyme International, Inc. | Non-toxic plant agent compositions and methods and uses thereof |
| US10557234B2 (en) | 2012-05-29 | 2020-02-11 | Neozyme International, Inc. | Papermaking additive compositions and methods and uses thereof |
| US10334856B2 (en) | 2012-05-29 | 2019-07-02 | Neozyme International, Inc. | Non-toxic pest control compositions and methods and uses thereof |
| US10306889B2 (en) | 2012-05-30 | 2019-06-04 | Bayer Cropscience Ag | Compositions comprising a biological control agent and an insecticide |
| BR122019010603B1 (pt) | 2012-05-30 | 2020-06-30 | Bayer Cropscience Ag | composição compreendendo um agente de controle biológico e um fungicida, seus usos, semente resistente a fitopatógenos, e método para reduzir o dano total das plantas e partes de plantas |
| WO2013178662A1 (fr) | 2012-05-30 | 2013-12-05 | Bayer Cropscience Ag | Compositions comprenant un agent de lutte biologique et un insecticide |
| CN104507319B (zh) | 2012-05-30 | 2018-08-03 | 拜尔农作物科学股份公司 | 包含生物防治剂和选自脂质膜合成抑制剂、黑素生物合成抑制剂、核酸合成抑制剂或信号转导抑制剂的杀真菌剂的组合物 |
| CN104507317B (zh) | 2012-05-30 | 2019-11-15 | 拜尔农作物科学股份公司 | 包含生物防治剂和杀真菌剂的组合物、及其用途、试剂盒 |
| JP6285423B2 (ja) | 2012-05-30 | 2018-02-28 | バイエル・クロップサイエンス・アクチェンゲゼルシャフト | 生物農薬および殺虫剤を含む組成物 |
| EP2854551A1 (fr) | 2012-05-30 | 2015-04-08 | Bayer Cropscience AG | Compositions contenant un agent de lutte biologique et un fongicide appartenant au groupe constitué des inhibiteurs des complexes i ou ii de la chaîne respiratoire |
| CN104470359B (zh) | 2012-05-30 | 2017-05-24 | 拜尔农作物科学股份公司 | 包括一种生物防治剂和一种杀虫剂的组合物 |
| AU2013269662B2 (en) | 2012-05-30 | 2016-12-15 | Bayer Cropscience Ag | Compositions comprising a biological control agent and an insecticide |
| ES2698061T3 (es) | 2012-05-30 | 2019-01-30 | Bayer Cropscience Ag | Composición que comprende un agente de control biológico y fluopicolida |
| US20150289514A1 (en) | 2012-05-30 | 2015-10-15 | Bayer Cropscience Ag | Composition comprising a biological control agent and a fungicide selected from inhibitors of the respiratory chain at complex iii |
| ES2689879T3 (es) | 2012-05-30 | 2018-11-16 | Bayer Cropscience Ag | Composición que comprende un agente de control biológico y un fungicida seleccionado de inhibidores de la biosíntesis del ergosterol |
| KR101715120B1 (ko) * | 2013-07-31 | 2017-03-13 | 한국화학연구원 | 스트렙토마이세스 스코풀리리디스 kr-001 균주 대량생산용 배지 조성물 |
| JP6273279B2 (ja) | 2012-08-14 | 2018-01-31 | コーリア リサーチ インスティテュート オブ ケミカル テクノロジー | ストレプトマイセス・スコプリリディスｋｒ−００１株またはその培養液を活性成分として含む雑草防除用組成物 |
| BR112015018693A2 (pt) | 2013-02-11 | 2017-07-18 | Bayer Cropscience Lp | composições compreendendo um agente de controle biológico à base de streptomyces e um inseticida |
| KR20150119022A (ko) | 2013-02-11 | 2015-10-23 | 바이엘 크롭사이언스 엘피 | 고제로틴 및 생물학적 방제제를 포함하는 조성물 |
| WO2015048627A1 (fr) * | 2013-09-30 | 2015-04-02 | Bayer Cropscience Lp, A Delaware Limited Partnership | Souches de streptomyces microflavus et leurs procédés d'utilisation pour le traitement et la prévention de la maladie du dragon jaune |
| EP2865267A1 (fr) | 2014-02-13 | 2015-04-29 | Bayer CropScience AG | Combinaisons de composés actifs comprenant des composés phénylamidine et agents de lutte biologique |
| EP2865265A1 (fr) | 2014-02-13 | 2015-04-29 | Bayer CropScience AG | Combinaisons de composés actifs comprenant des composés phénylamidine et agents de lutte biologique |
| WO2015160618A1 (fr) | 2014-04-16 | 2015-10-22 | Bayer Cropscience Lp | Compositions comprenant de la ningnanmycine et un agent de lutte biologique |
| AR100101A1 (es) * | 2014-04-16 | 2016-09-07 | Bayer Cropscience Lp | Cepas de streptomyces microflavus y métodos de uso de las mismas para controlar enfermedades y plagas en plantas |
| MX2017003452A (es) | 2014-09-17 | 2017-07-28 | Bayer Cropscience Lp | Composiciones que comprenden celulas recombinantes de bacillus y otro agente de control biologico. |
| CN104962501B (zh) * | 2015-07-20 | 2018-08-10 | 云南大学 | 一种抗蔬菜水果灰霉病的菌株、拮抗剂的制备及应用 |
| CN106342900B (zh) * | 2016-08-28 | 2019-09-10 | 佛山市艳晖生物科技有限公司 | 一种泾阳链霉菌可湿性粉剂及其制备方法 |
| CN111356761B (zh) * | 2017-09-11 | 2023-04-28 | 联邦科学和工业研究组织 | 用于植物病原体的生物防治的方法和组合物 |
| EP3878282A4 (fr) | 2018-11-02 | 2022-08-10 | Nihon Nohyaku Co., Ltd. | Composition d'agent de lutte contre les nuisibles et son procédé d'utilisation |
| CN112760248B (zh) * | 2020-12-30 | 2022-08-05 | 西南大学 | 一种可防治桃褐腐病的林肯链霉菌及其应用 |
| CN113957003B (zh) * | 2021-08-30 | 2022-12-30 | 中国热带农业科学院海口实验站 | 一种抗真菌的吸水链霉菌及其应用 |
| CN114176096B (zh) * | 2021-11-10 | 2024-01-19 | 河北兴柏农业科技股份有限公司 | 一种阿佛曼链霉菌活性孢子杀虫剂及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5373501A (en) | 1976-12-11 | 1978-06-30 | Kitasato Inst | Novel antibiotics amm2282 and process for preparing same |
| EP0263502A3 (fr) * | 1986-10-09 | 1990-05-02 | Ciba-Geigy Ag | Antibiotique-oligopeptide |
| JPH0737478B2 (ja) | 1987-05-29 | 1995-04-26 | クミアイ化学工業株式会社 | 新規生理活性物質ｋｓａ−９３４２又はその塩、及びその製造法 |
| FI82878C (fi) | 1988-04-14 | 1991-05-10 | Kemira Oy | Fungistatiskt foerfarande. |
| WO1994006788A1 (fr) * | 1992-09-15 | 1994-03-31 | Novo Nordisk A/S | Compose fongicide |
| US5527526A (en) | 1993-06-30 | 1996-06-18 | Idaho Research Foundation, Inc. | Use of streptomyces bacteria to control plant pathogens |
| US5403584A (en) | 1993-06-30 | 1995-04-04 | Idaho Research Foundation, Inc. | Use of Streptomyces WYEC 108 to control plant pathogens |
| KR100197077B1 (ko) | 1997-02-05 | 1999-06-15 | 서형원 | 항균성 미생물제제, 그 제조방법 및 처리방법 |
-
2000
- 2000-09-27 US US09/671,943 patent/US6524577B1/en not_active Expired - Lifetime
-
2001
- 2001-09-26 TW TW090124009A patent/TWI251465B/zh not_active IP Right Cessation
- 2001-09-27 DE DE60109948T patent/DE60109948T2/de not_active Expired - Lifetime
- 2001-09-27 AU AU9485401A patent/AU9485401A/xx active Pending
- 2001-09-27 NZ NZ525481A patent/NZ525481A/en not_active IP Right Cessation
- 2001-09-27 WO PCT/US2001/030393 patent/WO2002026041A2/fr active IP Right Grant
- 2001-09-27 IL IL15508701A patent/IL155087A0/xx not_active IP Right Cessation
- 2001-09-27 AT AT01975536T patent/ATE292385T1/de not_active IP Right Cessation
- 2001-09-27 EP EP01975536A patent/EP1322170B1/fr not_active Expired - Lifetime
- 2001-09-27 ES ES01975536T patent/ES2238483T3/es not_active Expired - Lifetime
- 2001-09-27 AU AU2001294854A patent/AU2001294854B8/en not_active Ceased
- 2001-09-27 JP JP2002529877A patent/JP5148802B2/ja not_active Expired - Fee Related
- 2001-09-27 KR KR1020037004428A patent/KR100908635B1/ko not_active IP Right Cessation
- 2001-09-27 US US09/966,982 patent/US6852317B2/en not_active Expired - Fee Related
- 2001-09-27 CA CA2423124A patent/CA2423124C/fr not_active Expired - Fee Related
- 2001-09-27 MX MXPA03002573A patent/MXPA03002573A/es active IP Right Grant
- 2001-09-27 BR BRPI0114192-9B1A patent/BR0114192B1/pt not_active IP Right Cessation
- 2001-09-27 BR BRBR122013013171-0A patent/BR122013013171B1/pt not_active IP Right Cessation
-
2003
- 2003-03-25 CR CR6933A patent/CR6933A/es not_active Application Discontinuation
- 2003-03-25 ZA ZA200302321A patent/ZA200302321B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60109948T2 (de) | 2006-02-02 |
| EP1322170B1 (fr) | 2005-04-06 |
| WO2002026041A3 (fr) | 2002-08-08 |
| ATE292385T1 (de) | 2005-04-15 |
| IL155087A0 (en) | 2003-10-31 |
| CA2423124C (fr) | 2012-05-22 |
| JP2004512834A (ja) | 2004-04-30 |
| US6852317B2 (en) | 2005-02-08 |
| US20030031741A1 (en) | 2003-02-13 |
| BR122013013171B1 (pt) | 2015-04-07 |
| AU2001294854B2 (en) | 2006-02-09 |
| AU2001294854B8 (en) | 2006-05-11 |
| CA2423124A1 (fr) | 2002-04-04 |
| WO2002026041A9 (fr) | 2003-11-13 |
| KR20030034222A (ko) | 2003-05-01 |
| DE60109948D1 (de) | 2005-05-12 |
| KR100908635B1 (ko) | 2009-07-21 |
| US6524577B1 (en) | 2003-02-25 |
| BR0114192A (pt) | 2004-03-23 |
| BR0114192B1 (pt) | 2014-07-15 |
| EP1322170A2 (fr) | 2003-07-02 |
| ES2238483T3 (es) | 2005-09-01 |
| MXPA03002573A (es) | 2004-08-12 |
| CR6933A (es) | 2008-11-26 |
| JP5148802B2 (ja) | 2013-02-20 |
| TWI251465B (en) | 2006-03-21 |
| AU9485401A (en) | 2002-04-08 |
| WO2002026041A2 (fr) | 2002-04-04 |
| NZ525481A (en) | 2004-10-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1322170B1 (fr) | Souche de streptomyces destinee a lutter contre des maladies vegetales | |
| AU2001294854A1 (en) | A novel strain of streptomyces for controlling plant diseases | |
| US6280719B1 (en) | Antifungal biocontrol agents, a process for preparing and treating the same | |
| US6586231B2 (en) | Strain of bacillus for controlling plant diseases | |
| US6077506A (en) | Strain of bacillus for controlling plant disease | |
| US5968503A (en) | Use of streptomyces bacteria to control plant pathogens and degrade turf thatch | |
| US5589381A (en) | Bacillus licheniformis producing antifungal agents and uses thereof for control of phytopathogenic fungi | |
| CA2216794C (fr) | Utilisation de bacteries streptomyces dans la lutte contre les agents pathogenes vegetaux et dans la degradation du chaume du gazon | |
| JP2002539820A (ja) | 植物の病気を制御するためのＢａｃｉｌｌｕｓｐｕｍｉｌｕｓ菌株 | |
| MXPA01004814A (es) | Composiciones y metodos para controlar plagas de plantas | |
| PL198772B1 (pl) | Biologicznie czysta kultura Bacillus subtilis, jej metabolit i supernatant z hodowli szczepu, kompozycje do ochrony roślin i owoców przed szkodnikami, sposób ochrony lub leczenia roślin i owoców, agrastatyny, sposób izolowania supernatantu o aktywności owadobójczej | |
| AU2001257595A1 (en) | Streptomyces strain with insecticidal activity and method of using as an insecticide | |
| NZ522369A (en) | Supernatants and metabolites that have insecticidal activity from a Streptomyces strain | |
| KR20040080699A (ko) | 고추 역병균에 항균활성을 갖는 신규 레체발리에리아에어로콜로니제네스 ｖｋ-ａ9 균주 및 이 균주로부터생산되는 신규 항생물질의 제조방법 |