ZA200210102B - HMG-CoA reductase inhibitors and their use as medicaments for the treatment of cholesterol related diseases. - Google Patents
HMG-CoA reductase inhibitors and their use as medicaments for the treatment of cholesterol related diseases. Download PDFInfo
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- ZA200210102B ZA200210102B ZA200210102A ZA200210102A ZA200210102B ZA 200210102 B ZA200210102 B ZA 200210102B ZA 200210102 A ZA200210102 A ZA 200210102A ZA 200210102 A ZA200210102 A ZA 200210102A ZA 200210102 B ZA200210102 B ZA 200210102B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21159400P | 2000-06-15 | 2000-06-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200210102B true ZA200210102B (en) | 2004-03-12 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| ZA200210102A ZA200210102B (en) | 2000-06-15 | 2002-12-12 | HMG-CoA reductase inhibitors and their use as medicaments for the treatment of cholesterol related diseases. |
Country Status (20)
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| EP (1) | EP1294696A2 (zh) |
| JP (1) | JP2004503541A (zh) |
| KR (1) | KR20030010720A (zh) |
| CN (1) | CN1436174A (zh) |
| AR (1) | AR028732A1 (zh) |
| AU (1) | AU2001266860A1 (zh) |
| BR (1) | BR0111571A (zh) |
| CA (1) | CA2412979A1 (zh) |
| CZ (1) | CZ20023931A3 (zh) |
| EC (1) | ECSP024386A (zh) |
| HU (1) | HUP0302955A3 (zh) |
| IL (1) | IL152718A0 (zh) |
| MX (1) | MXPA02012415A (zh) |
| NO (1) | NO20026011L (zh) |
| PE (1) | PE20011364A1 (zh) |
| PL (1) | PL362477A1 (zh) |
| UY (1) | UY26776A1 (zh) |
| WO (1) | WO2001096311A2 (zh) |
| ZA (1) | ZA200210102B (zh) |
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| US20110196039A9 (en) * | 1994-10-05 | 2011-08-11 | Kaesemeyer Wayne H | Controlled release arginine formulations |
| BR0113200A (pt) * | 2000-08-15 | 2003-09-16 | Pfizer Prod Inc | Combinação terapêutica |
| TR200400600T3 (tr) * | 2001-06-06 | 2004-06-21 | Bristol-Myers Squibb Company | Kiral diol sülfonlar ve dihidroksi asit HMG COA redüktaz inhibitörlerinin hazırlanmsı için işlem |
| DE60219793T2 (de) | 2001-07-11 | 2008-01-24 | Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield | Verfahren zur Behandlung von Cytokin-Vermittelten Erkrankungen |
| MXPA04002330A (es) | 2001-09-14 | 2005-04-08 | Japan Tobacco Inc | Compuestos biarilo ligados. |
| GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205170D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205176D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| AU2003225102A1 (en) * | 2002-04-23 | 2003-11-10 | Bristol-Myers Squibb Company | Modified-release vasopeptidase inhibitor formulation, combinations and method |
| US20050192245A1 (en) * | 2002-07-18 | 2005-09-01 | Sankyo Company, Limited | Medicinal composition for treating arteriosclerosis |
| IL166312A0 (en) * | 2002-07-18 | 2006-01-15 | Sankyo Co | A pharmaceutical composition containing an adp receptor antagonist and an acat inhibitor |
| AU2003250701A1 (en) * | 2002-07-31 | 2004-02-16 | Wayne R. Danter | Protein tyrosine kinase inhibitors |
| GB0220885D0 (en) * | 2002-09-09 | 2002-10-16 | Novartis Ag | Organic compounds |
| ES2298563T3 (es) * | 2002-10-09 | 2008-05-16 | Critical Outcome Technologies, Inc. | Inhibidores de proteinas tirosina cinasas. |
| FR2848452B1 (fr) * | 2002-12-12 | 2007-04-06 | Aventis Pharma Sa | Application des inhibiteurs de recapture intestinale des acides biliaires pour la prevention et le traitement de la maladie d'alzheimer |
| GEP20084406B (en) | 2003-05-30 | 2008-06-25 | Ranbaxy Lab Ltd | Substituted pyrrole derivatives and their use as hmg-co inhibitors |
| US20070161700A1 (en) | 2004-12-28 | 2007-07-12 | Kowa Company, Ltd. | Inhibitor for the formation of y-secretase complex |
| EP1729761A4 (en) * | 2004-03-05 | 2008-09-03 | Eisai Co Ltd | TREATMENT OF CADASIL WITH CHOLINESTERASE INHIBITORS |
| KR20060133008A (ko) * | 2004-04-14 | 2006-12-22 | 워너-램버트 캄파니 엘엘씨 | 알츠하이머병을 치료하기 위한 치료용 조합물 |
| ATE493973T1 (de) * | 2004-06-04 | 2011-01-15 | Teva Pharma | Irbesartan enthaltende pharmazeutische zusammensetzung |
| WO2006110882A2 (en) * | 2005-04-12 | 2006-10-19 | Psivida Inc. | Hmgcoa reductase inhibitor codrugs and uses thereof |
| WO2007016306A2 (en) * | 2005-08-01 | 2007-02-08 | Psivida Inc. | HMGCoA REDUCTASE INHIBITOR CODRUGS AND USES THEREOF |
| AU2006313430B2 (en) * | 2005-11-08 | 2012-09-06 | Ranbaxy Laboratories Limited | Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt |
| WO2007091338A1 (ja) * | 2006-02-07 | 2007-08-16 | Mochida Pharmaceutical Co., Ltd. | 脳卒中再発予防用組成物 |
| NZ594178A (en) * | 2006-02-27 | 2013-02-22 | Targeted Molecular Diagnostics Llc | An ex vivo method of predicting toxicity to tyrosine kinase inhibitors |
| CA2645281A1 (en) * | 2006-03-29 | 2007-10-04 | Kowa Co., Ltd. | Triglyceride-lowering agent and hyperinsulinism-ameliorating agent |
| WO2008059519A2 (en) * | 2006-09-25 | 2008-05-22 | Glenmark Pharmaceuticals Limited | A process for the preparation of intermediates of rosuvastatin |
| US8034815B2 (en) | 2007-01-11 | 2011-10-11 | Critical Outcome Technologies, Inc. | Compounds and method for treatment of cancer |
| US8404275B2 (en) | 2007-07-01 | 2013-03-26 | Vitalis Llc | Combination tablet with chewable outer layer |
| KR100900044B1 (ko) * | 2007-07-05 | 2009-06-01 | 한국식품연구원 | 3-하이드록시-3-메틸글루타릴 보조효소 ａ 환원효소 저해용펩타이드 및 이를 함유하는 고콜레스테롤로 인한 심장질환 및 심혈관계 질환 치료제 |
| TWI432195B (zh) | 2007-10-03 | 2014-04-01 | Kowa Co | 神經細胞死亡抑制劑 |
| EP2225226B1 (en) | 2007-12-26 | 2016-08-17 | Critical Outcome Technologies, Inc. | Compounds and their use in a method for treatment of cancer |
| CA2730890C (en) | 2008-07-17 | 2018-05-15 | Critical Outcome Technologies Inc. | Thiosemicarbazone inhibitor compounds and cancer treatment methods |
| KR101104335B1 (ko) * | 2009-03-06 | 2012-01-16 | 가톨릭대학교 산학협력단 | 알카노일화된 히알루론산으로 형성된 나노입자 및 그 제조방법 |
| EP3235818A3 (en) | 2010-04-01 | 2018-03-14 | Critical Outcome Technologies, Inc. | Compounds for the treatment of hiv |
| US9056134B2 (en) * | 2010-07-21 | 2015-06-16 | Nucitec S.A. De C.V. | Single daily dosage form for prevention and treatment of metabolic syndrome |
| US8877221B2 (en) | 2010-10-27 | 2014-11-04 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same |
| US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
| US8865900B2 (en) | 2011-01-18 | 2014-10-21 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Methyltetrazole sulfides and sulfones |
| CN103313983B (zh) | 2011-01-18 | 2016-06-29 | 中化帝斯曼制药有限公司荷兰公司 | 在碱存在下制备他汀类化合物的方法 |
| MX2013008285A (es) | 2011-01-18 | 2013-09-13 | Dsm Sinochem Pharm Bv | Procedimiento para la preparacion de diolsulfonas. |
| US9308190B2 (en) | 2011-06-06 | 2016-04-12 | Warsaw Orthopedic, Inc. | Methods and compositions to enhance bone growth comprising a statin |
| CN104105478A (zh) | 2011-10-28 | 2014-10-15 | 维塔利斯公司 | 抗发红组合物 |
| MX363563B (es) | 2011-12-09 | 2019-03-27 | Dsm Sinochem Pharm Nl Bv | Proceso para la preparación de un tioprecursor de estatinas. |
| MX359424B (es) | 2011-12-09 | 2018-09-12 | Dsm Sinochem Pharm Nl Bv | Proceso para la preparación de un precursor de estatina. |
| JP6041985B2 (ja) * | 2012-06-08 | 2016-12-14 | ミレ ファイン ケミカル カンパニー リミテッド | 結晶型ｔ−ブチル２−［（４Ｒ，６Ｓ）−６−ホルミル−２，２−ジメチル−１，３−ジオキサン−４−イル］アセテート及びその製造方法 |
| US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
| US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
| CN112159403B (zh) | 2020-09-30 | 2022-04-15 | 复旦大学 | 一种用于合成他汀类药物的关键中间体的制备方法 |
| CN114213350B (zh) * | 2021-12-29 | 2024-03-19 | 江苏福瑞康泰药业有限公司 | 一种他汀类药物中间体的制备方法 |
| CN114437052B (zh) * | 2021-12-31 | 2024-03-29 | 江苏阿尔法集团福瑞药业(宿迁)有限公司 | 一种利用连续流微通道反应器合成他汀类药物中间体的方法 |
| CN114601039A (zh) * | 2022-03-16 | 2022-06-10 | 江苏省农业科学院 | 一种提高热应激下绵羊发情率和受胎率的方法 |
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| US5506219A (en) * | 1988-08-29 | 1996-04-09 | E. R. Squibb & Sons, Inc. | Pyridine anchors for HMG-CoA reductase inhibitors |
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- 2001-06-12 AU AU2001266860A patent/AU2001266860A1/en not_active Abandoned
- 2001-06-12 PL PL01362477A patent/PL362477A1/xx not_active Application Discontinuation
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- 2001-06-12 KR KR1020027017087A patent/KR20030010720A/ko not_active Application Discontinuation
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Also Published As
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|---|---|
| NO20026011D0 (no) | 2002-12-13 |
| HUP0302955A2 (hu) | 2003-12-29 |
| WO2001096311A3 (en) | 2002-07-11 |
| US20020028826A1 (en) | 2002-03-07 |
| WO2001096311A2 (en) | 2001-12-20 |
| HUP0302955A3 (en) | 2005-08-29 |
| AU2001266860A1 (en) | 2001-12-24 |
| CN1436174A (zh) | 2003-08-13 |
| KR20030010720A (ko) | 2003-02-05 |
| CZ20023931A3 (cs) | 2003-03-12 |
| MXPA02012415A (es) | 2003-06-06 |
| PL362477A1 (en) | 2004-11-02 |
| PE20011364A1 (es) | 2002-02-27 |
| UY26776A1 (es) | 2002-01-31 |
| EP1294696A2 (en) | 2003-03-26 |
| CA2412979A1 (en) | 2001-12-20 |
| JP2004503541A (ja) | 2004-02-05 |
| BR0111571A (pt) | 2003-07-01 |
| AR028732A1 (es) | 2003-05-21 |
| IL152718A0 (en) | 2003-06-24 |
| ECSP024386A (es) | 2003-03-10 |
| NO20026011L (no) | 2003-02-12 |
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