ZA200206153B - Proteins comprising conserved regions of Neisseria meningitidis surface antigent NhhA. - Google Patents
Proteins comprising conserved regions of Neisseria meningitidis surface antigent NhhA.Info
- Publication number
- ZA200206153B ZA200206153B ZA200206153A ZA200206153A ZA200206153B ZA 200206153 B ZA200206153 B ZA 200206153B ZA 200206153 A ZA200206153 A ZA 200206153A ZA 200206153 A ZA200206153 A ZA 200206153A ZA 200206153 B ZA200206153 B ZA 200206153B
- Authority
- ZA
- South Africa
- Prior art keywords
- antigent
- nhha
- proteins
- neisseria meningitidis
- conserved regions
- Prior art date
Links
- 241000588650 Neisseria meningitidis Species 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17791700P | 2000-01-25 | 2000-01-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200206153B true ZA200206153B (en) | 2003-11-03 |
Family
ID=22650445
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200206153A ZA200206153B (en) | 2000-01-25 | 2002-08-01 | Proteins comprising conserved regions of Neisseria meningitidis surface antigent NhhA. |
Country Status (18)
Country | Link |
---|---|
US (4) | US7947291B2 (pl) |
EP (2) | EP1252182B1 (pl) |
JP (3) | JP2003523208A (pl) |
KR (1) | KR100698561B1 (pl) |
CN (2) | CN102417537A (pl) |
AU (1) | AU2818101A (pl) |
BR (1) | BR0107857A (pl) |
CA (1) | CA2398139A1 (pl) |
CZ (1) | CZ304379B6 (pl) |
ES (1) | ES2389719T3 (pl) |
HU (1) | HUP0300696A3 (pl) |
IL (2) | IL150822A0 (pl) |
MX (1) | MXPA02007184A (pl) |
NO (1) | NO332229B1 (pl) |
NZ (1) | NZ520445A (pl) |
PL (1) | PL216780B1 (pl) |
WO (1) | WO2001055182A1 (pl) |
ZA (1) | ZA200206153B (pl) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2210945B1 (en) * | 1998-01-14 | 2013-06-26 | Novartis Vaccines and Diagnostics S.r.l. | Neisseria meningitidis antigens |
AU761780B2 (en) | 1998-05-01 | 2003-06-12 | Glaxosmithkline Biologicals Sa | Neisseria meningitidis antigens and compositions |
US7368261B1 (en) * | 1999-04-30 | 2008-05-06 | Novartis Vaccines And Diagnostics Srl | Conserved Neisserial antigens |
ES2563677T3 (es) * | 1999-05-19 | 2016-03-15 | Glaxosmithkline Biologicals Sa | Composiciones de combinaciones de Neisseria |
GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
WO2001055182A1 (en) * | 2000-01-25 | 2001-08-02 | The University Of Queensland | PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA |
NZ521396A (en) | 2000-02-28 | 2004-06-25 | Chiron S | Fusion proteins comprising two or more Neisseria polypeptides |
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
PT1524993E (pt) * | 2002-08-02 | 2013-06-12 | Glaxosmithkline Biolog Sa | Composições de vacina de neisseria compreendendo uma combinação de antigénios |
GB0220199D0 (en) * | 2002-08-30 | 2002-10-09 | Univ Utrecht | Mutant protein and refolding method |
EP2353608B1 (en) | 2002-10-11 | 2019-12-18 | Novartis Vaccines and Diagnostics S.r.l. | Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages |
GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
WO2007042326A2 (en) * | 2005-10-14 | 2007-04-19 | Intercell Ag | Neisseria meningitidis antigens |
ES2337309T5 (es) | 2006-06-12 | 2013-07-30 | Glaxosmithkline Biologicals S.A. | Vacuna |
CA2747340A1 (en) | 2008-12-17 | 2010-06-24 | Novartis Ag | Meningococcal vaccines including hemoglobin receptor |
RU2555757C2 (ru) | 2009-03-24 | 2015-07-10 | Новартис Аг | Комбинации менингококкового фактор н-связывающего белка и пневмококковых сахаридных конъюгатов |
CA2756522C (en) | 2009-03-24 | 2018-06-26 | Novartis Ag | Adjuvanting meningococcal factor h binding protein |
WO2011024071A1 (en) | 2009-08-27 | 2011-03-03 | Novartis Ag | Adjuvant comprising aluminium, oligonucleotide and polycation |
JP2013502918A (ja) | 2009-08-27 | 2013-01-31 | ノバルティス アーゲー | 髄膜炎菌fHBP配列を含むハイブリッドポリペプチド |
CN102724988B (zh) | 2009-09-30 | 2014-09-10 | 诺华股份有限公司 | 脑膜炎球菌fHBP多肽的表达 |
WO2011051893A1 (en) | 2009-10-27 | 2011-05-05 | Novartis Ag | Modified meningococcal fhbp polypeptides |
CN102869378A (zh) | 2010-03-10 | 2013-01-09 | 葛兰素史密丝克莱恩生物有限公司 | 免疫原性组合物 |
ES2663872T3 (es) | 2010-03-11 | 2018-04-17 | Glaxosmithkline Biologicals S.A. | Composición inmunogénica o vacuna contra infección o enfermedad bacteriana gramnegativa, por ejemplo, por Neisseria |
CN102802662A (zh) | 2010-03-18 | 2012-11-28 | 诺华有限公司 | 用于脑膜炎球菌血清组b的含佐剂疫苗 |
WO2011161653A1 (en) | 2010-06-25 | 2011-12-29 | Novartis Ag | Combinations of meningococcal factor h binding proteins |
CA2806613A1 (en) * | 2010-07-30 | 2012-02-02 | Griffith University | Recombinant neisseria meningitidis pora porin proteins |
GB201015132D0 (en) | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
ES2759484T3 (es) | 2010-09-10 | 2020-05-11 | Glaxosmithkline Biologicals Sa | Meningococo que sobreexpresa NadA y/o NHBA y vesículas de la membrana externa derivadas del mismo |
WO2012054879A1 (en) * | 2010-10-22 | 2012-04-26 | Duke University | Compositions and methods for the treatment of septic arthritis, osteomyelitis, and bacteremia |
EP2707009A1 (en) | 2011-05-12 | 2014-03-19 | Novartis AG | Antipyretics to enhance tolerability of vesicle-based vaccines |
US10596246B2 (en) | 2011-12-29 | 2020-03-24 | Glaxosmithkline Biological Sa | Adjuvanted combinations of meningococcal factor H binding proteins |
ES2654613T3 (es) | 2012-02-02 | 2018-02-14 | Glaxosmithkline Biologicals Sa | Promotores para una expresión aumentada de proteínas en meningococos |
ES2750366T3 (es) | 2012-03-08 | 2020-03-25 | Glaxosmithkline Biologicals Sa | Ensayo de potencia in vitro para vacunas meningocócicas basadas en proteína |
CA2876138C (en) | 2012-06-14 | 2023-09-19 | Novartis Ag | Vaccines for serogroup x meningococcus |
CN104602705A (zh) | 2012-09-06 | 2015-05-06 | 诺华股份有限公司 | 血清组b脑膜炎球菌和d/t/p的联合疫苗 |
BR112016019735A2 (pt) | 2014-02-28 | 2017-10-17 | Glaxosmithkline Biologicals Sa | fhbp, polipeptídeo, plasmídeo ou outro ácido nucleico, célula hospedeira, vesículas de membrana, e, composição imunogênica |
BR112019010227A2 (pt) | 2016-11-25 | 2019-10-08 | Glaxosmithkline Biologicals Sa | conjugado imunogênico, processo para preparação de conjugado imunogênico, composição imunogênica, vacina, e, uso de nomv |
EP3544637B1 (en) | 2016-11-25 | 2020-11-11 | GlaxoSmithKline Biologicals S.A. | Native omv-antigen conjugates and use thereof |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4843000A (en) | 1979-12-26 | 1989-06-27 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay |
US4849338A (en) | 1982-07-16 | 1989-07-18 | Syntex (U.S.A.) Inc. | Simultaneous calibration heterogeneous immunoassay |
US4550081A (en) | 1980-05-19 | 1985-10-29 | The Board Of Trustees Of The Leland Stanford Jr. University | Non-reverting salmonella |
US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
US4603112A (en) | 1981-12-24 | 1986-07-29 | Health Research, Incorporated | Modified vaccinia virus |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
EP0273116A3 (en) | 1986-10-09 | 1990-05-02 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Gonococcal and meningococcal polypeptides, vaccines and diagnostics |
US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
US5785973A (en) | 1988-02-01 | 1998-07-28 | Praxis Biologics, Inc. | Synthetic peptides representing a T-cell epitope as a carrier molecule for conjugate vaccines |
WO1989009385A1 (fr) | 1988-03-24 | 1989-10-05 | Zach, Johann | Dispositif manometrique ou dynamometrique |
ES2070312T5 (es) * | 1988-12-19 | 2003-05-16 | American Cyanamid Co | Vacuna de proteina de membrana exterior meningococica de clase 1. |
AU649066B2 (en) | 1990-07-25 | 1994-05-12 | Syngene, Inc. | Circular extension for generating multiple nucleic acid complements |
US5422252A (en) | 1993-06-04 | 1995-06-06 | Becton, Dickinson And Company | Simultaneous amplification of multiple targets |
US5646259A (en) | 1995-03-24 | 1997-07-08 | St. Louis University | DNA encoding haemophilus adhesion proteins |
DK0862656T3 (da) | 1995-11-21 | 2001-04-09 | Univ Yale | Unimolekylær segmentamplifikation og -detektering |
GB9611673D0 (en) * | 1996-06-05 | 1996-08-07 | Peptide Therapeutics Ltd | Meningococcal vaccine |
AU9363798A (en) | 1997-11-06 | 1999-05-31 | Chiron S.P.A. | Neisserial antigens |
GB9726398D0 (en) * | 1997-12-12 | 1998-02-11 | Isis Innovation | Polypeptide and coding sequences |
EP2210945B1 (en) | 1998-01-14 | 2013-06-26 | Novartis Vaccines and Diagnostics S.r.l. | Neisseria meningitidis antigens |
AU761780B2 (en) | 1998-05-01 | 2003-06-12 | Glaxosmithkline Biologicals Sa | Neisseria meningitidis antigens and compositions |
GB9810276D0 (en) * | 1998-05-13 | 1998-07-15 | Smithkline Beecham Biolog | Novel compounds |
WO2000061165A1 (en) * | 1999-04-13 | 2000-10-19 | Smithkline Beecham Corporation | Conserved adhesin motif and methods of use thereof |
US7368261B1 (en) * | 1999-04-30 | 2008-05-06 | Novartis Vaccines And Diagnostics Srl | Conserved Neisserial antigens |
EP1605061A1 (en) * | 1999-04-30 | 2005-12-14 | Chiron Corporation | Neisseria genomic sequences and methods of their use |
GB9916529D0 (en) | 1999-07-14 | 1999-09-15 | Chiron Spa | Antigenic peptides |
WO2001055182A1 (en) * | 2000-01-25 | 2001-08-02 | The University Of Queensland | PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA |
PT1524993E (pt) * | 2002-08-02 | 2013-06-12 | Glaxosmithkline Biolog Sa | Composições de vacina de neisseria compreendendo uma combinação de antigénios |
EP1706481A2 (en) * | 2003-12-23 | 2006-10-04 | GlaxoSmithKline Biologicals S.A. | Vaccine |
-
2001
- 2001-01-25 WO PCT/AU2001/000069 patent/WO2001055182A1/en active IP Right Grant
- 2001-01-25 EP EP01946868A patent/EP1252182B1/en not_active Expired - Lifetime
- 2001-01-25 KR KR1020027009512A patent/KR100698561B1/ko not_active IP Right Cessation
- 2001-01-25 NZ NZ520445A patent/NZ520445A/en not_active IP Right Cessation
- 2001-01-25 CZ CZ2002-2482A patent/CZ304379B6/cs not_active IP Right Cessation
- 2001-01-25 CN CN2011102811093A patent/CN102417537A/zh active Pending
- 2001-01-25 MX MXPA02007184A patent/MXPA02007184A/es active IP Right Grant
- 2001-01-25 BR BR0107857-7A patent/BR0107857A/pt active Search and Examination
- 2001-01-25 HU HU0300696A patent/HUP0300696A3/hu unknown
- 2001-01-25 EP EP10184045A patent/EP2395013A3/en not_active Withdrawn
- 2001-01-25 AU AU28181/01A patent/AU2818101A/en not_active Abandoned
- 2001-01-25 ES ES01946868T patent/ES2389719T3/es not_active Expired - Lifetime
- 2001-01-25 CN CN01807183A patent/CN1419564A/zh active Pending
- 2001-01-25 JP JP2001561034A patent/JP2003523208A/ja active Pending
- 2001-01-25 US US09/771,382 patent/US7947291B2/en not_active Expired - Fee Related
- 2001-01-25 IL IL15082201A patent/IL150822A0/xx unknown
- 2001-01-25 CA CA002398139A patent/CA2398139A1/en not_active Abandoned
- 2001-01-25 PL PL356819A patent/PL216780B1/pl not_active IP Right Cessation
-
2002
- 2002-07-18 IL IL150822A patent/IL150822A/en not_active IP Right Cessation
- 2002-07-22 NO NO20023487A patent/NO332229B1/no not_active IP Right Cessation
- 2002-08-01 ZA ZA200206153A patent/ZA200206153B/xx unknown
-
2007
- 2007-10-31 US US11/933,411 patent/US8383790B2/en not_active Expired - Fee Related
- 2007-10-31 US US11/933,245 patent/US8367070B2/en not_active Expired - Fee Related
-
2011
- 2011-09-30 JP JP2011218296A patent/JP2012051902A/ja active Pending
-
2013
- 2013-02-01 US US13/757,124 patent/US20130136762A1/en not_active Abandoned
- 2013-09-11 JP JP2013188798A patent/JP2014024849A/ja active Pending
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