PL356819A1 - Białka zawierające konserwowane obszary powierzchniowego antygenu NhhA z Neisseria meningitidis - Google Patents

Białka zawierające konserwowane obszary powierzchniowego antygenu NhhA z Neisseria meningitidis

Info

Publication number
PL356819A1
PL356819A1 PL01356819A PL35681901A PL356819A1 PL 356819 A1 PL356819 A1 PL 356819A1 PL 01356819 A PL01356819 A PL 01356819A PL 35681901 A PL35681901 A PL 35681901A PL 356819 A1 PL356819 A1 PL 356819A1
Authority
PL
Poland
Prior art keywords
nhha
proteins
surface antigen
neisseria meningitidis
conserved regions
Prior art date
Application number
PL01356819A
Other languages
English (en)
Other versions
PL216780B1 (pl
Inventor
Ian Richard Anselm Peak
Michael Paul Jennings
Original Assignee
University Of Queensland Of Santa Lucia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Queensland Of Santa Lucia filed Critical University Of Queensland Of Santa Lucia
Publication of PL356819A1 publication Critical patent/PL356819A1/pl
Publication of PL216780B1 publication Critical patent/PL216780B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL356819A 2000-01-25 2001-01-25 Wyizolowane białka zawierające konserwatywne obszary antygenu powierzchniowego NhhA z Neisseria meningitidis, białka fuzyjne, kompozycja farmaceutyczna, przeciwciało monoklonalne lub wiążący antygen fragment przeciwciała monoklonalnego, wyizolowany kwas nukleinowy, konstrukt ekspresyjny, komórka gospodarza, sposób wytwarzania rekombinowanego białka, sposób wykrywania N. meningitidis w próbce biologicznej, sposób diagnozowania zakażenia N. meningitidis oraz sposób wykrywania N. meningitidis w próbce biologicznej uzyskanej od pacjenta oraz zastosowanie wyizolowanego białka, białka fuzyjnego i konstruktu ekspresyjnego PL216780B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17791700P 2000-01-25 2000-01-25
PCT/AU2001/000069 WO2001055182A1 (en) 2000-01-25 2001-01-25 PROTEINS COMPRISING CONSERVED REGIONS OF NEISSERIA MENINGITIDIS SURFACE ANTIGEN NhhA

Publications (2)

Publication Number Publication Date
PL356819A1 true PL356819A1 (pl) 2004-07-12
PL216780B1 PL216780B1 (pl) 2014-05-30

Family

ID=22650445

Family Applications (1)

Application Number Title Priority Date Filing Date
PL356819A PL216780B1 (pl) 2000-01-25 2001-01-25 Wyizolowane białka zawierające konserwatywne obszary antygenu powierzchniowego NhhA z Neisseria meningitidis, białka fuzyjne, kompozycja farmaceutyczna, przeciwciało monoklonalne lub wiążący antygen fragment przeciwciała monoklonalnego, wyizolowany kwas nukleinowy, konstrukt ekspresyjny, komórka gospodarza, sposób wytwarzania rekombinowanego białka, sposób wykrywania N. meningitidis w próbce biologicznej, sposób diagnozowania zakażenia N. meningitidis oraz sposób wykrywania N. meningitidis w próbce biologicznej uzyskanej od pacjenta oraz zastosowanie wyizolowanego białka, białka fuzyjnego i konstruktu ekspresyjnego

Country Status (18)

Country Link
US (4) US7947291B2 (pl)
EP (2) EP1252182B1 (pl)
JP (3) JP2003523208A (pl)
KR (1) KR100698561B1 (pl)
CN (2) CN102417537A (pl)
AU (1) AU2818101A (pl)
BR (1) BR0107857A (pl)
CA (1) CA2398139A1 (pl)
CZ (1) CZ304379B6 (pl)
ES (1) ES2389719T3 (pl)
HU (1) HUP0300696A3 (pl)
IL (2) IL150822A0 (pl)
MX (1) MXPA02007184A (pl)
NO (1) NO332229B1 (pl)
NZ (1) NZ520445A (pl)
PL (1) PL216780B1 (pl)
WO (1) WO2001055182A1 (pl)
ZA (1) ZA200206153B (pl)

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JP2006506467A (ja) 2002-08-02 2006-02-23 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン組成物
SI2351579T1 (sl) 2002-10-11 2017-05-31 Glaxosmithkline Biologicals Sa Polipeptidna cepiva za široko zaščito proti hipervirulentnim meningokoknim linijam
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AU2010288239B2 (en) 2009-08-27 2014-01-16 Novartis Ag Adjuvant comprising aluminium, oligonucleotide and polycation
EP2470204B1 (en) 2009-08-27 2015-12-16 GlaxoSmithKline Biologicals SA Hybrid polypeptides including meningococcal fhbp sequences
WO2011039631A2 (en) 2009-09-30 2011-04-07 Novartis Ag Expression of meningococcal fhbp polypeptides
BR112012010531A2 (pt) 2009-10-27 2019-09-24 Novartis Ag "polipeptídeos de modificação meningocócica fhbp"
JP2013521770A (ja) 2010-03-10 2013-06-13 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン組成物
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CA2793510A1 (en) 2010-03-18 2012-02-16 Novartis Ag Adjuvanted vaccines for serogroup b meningococcus
WO2011161653A1 (en) 2010-06-25 2011-12-29 Novartis Ag Combinations of meningococcal factor h binding proteins
JP2013541322A (ja) * 2010-07-30 2013-11-14 グリフィス・ユニバーシティ 組換え髄膜炎菌（ナイセリア・メニンギティディス）ＰｏｒＡポーリンタンパク質
BR112013005626B1 (pt) 2010-09-10 2022-07-26 Glaxosmithkline Biologicals Sa Meningococo, processo para a preparação de uma cepa meningocócica, vesículas de membrana externa, composição farmacêutica imunogênica, e, uso de uma composição
GB201015132D0 (en) 2010-09-10 2010-10-27 Univ Bristol Vaccine composition
WO2012054879A1 (en) * 2010-10-22 2012-04-26 Duke University Compositions and methods for the treatment of septic arthritis, osteomyelitis, and bacteremia
WO2012153302A1 (en) 2011-05-12 2012-11-15 Novartis Ag Antipyretics to enhance tolerability of vesicle-based vaccines
BR112014016223A8 (pt) 2011-12-29 2017-07-04 Novartis Ag combinações adjuvantes de proteínas de ligação de fator h meningocócico
ES2654613T3 (es) 2012-02-02 2018-02-14 Glaxosmithkline Biologicals Sa Promotores para una expresión aumentada de proteínas en meningococos
EP2823312B1 (en) 2012-03-08 2019-08-07 GlaxoSmithKline Biologicals SA In vitro potency assay for protein-based meningococcal vaccines
NZ630133A (en) 2012-06-14 2016-10-28 Novartis Ag Vaccines for serogroup x meningococcus
AU2013311702A1 (en) 2012-09-06 2015-02-19 Novartis Ag Combination vaccines with serogroup B meningococcus and D/T/P
HUE052293T2 (hu) 2014-02-28 2021-04-28 Glaxosmithkline Biologicals Sa Módosított fHbp meningococcus-polipeptidek
PT3544637T (pt) 2016-11-25 2021-02-03 Glaxosmithkline Biologicals Sa Conjugados omv-antigénio nativos e sua utilização
WO2018096007A2 (en) 2016-11-25 2018-05-31 Glaxosmithkline Biologicals S.A. Immunogenic conjugates and use thereof

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Also Published As

Publication number Publication date
CZ20022482A3 (cs) 2003-01-15
WO2001055182A1 (en) 2001-08-02
KR100698561B1 (ko) 2007-03-21
EP2395013A3 (en) 2012-03-21
US20020160016A1 (en) 2002-10-31
US7947291B2 (en) 2011-05-24
US20130136762A1 (en) 2013-05-30
NZ520445A (en) 2004-02-27
PL216780B1 (pl) 2014-05-30
CN102417537A (zh) 2012-04-18
IL150822A0 (en) 2003-02-12
NO20023487L (no) 2002-09-24
EP1252182B1 (en) 2012-06-20
BR0107857A (pt) 2002-10-29
IL150822A (en) 2011-06-30
HUP0300696A2 (hu) 2003-07-28
EP2395013A2 (en) 2011-12-14
CA2398139A1 (en) 2001-08-02
CZ304379B6 (cs) 2014-04-09
HUP0300696A3 (en) 2004-10-28
NO332229B1 (no) 2012-08-06
EP1252182A4 (en) 2005-03-02
JP2014024849A (ja) 2014-02-06
ES2389719T3 (es) 2012-10-30
AU2818101A (en) 2001-08-07
CN1419564A (zh) 2003-05-21
US20090068229A1 (en) 2009-03-12
EP1252182A1 (en) 2002-10-30
KR20020065938A (ko) 2002-08-14
JP2012051902A (ja) 2012-03-15
MXPA02007184A (es) 2004-02-26
NO20023487D0 (no) 2002-07-22
ZA200206153B (en) 2003-11-03
US8383790B2 (en) 2013-02-26
US8367070B2 (en) 2013-02-05
JP2003523208A (ja) 2003-08-05
US20090068216A1 (en) 2009-03-12

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Legal Events

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LAPS Decisions on the lapse of the protection rights

Effective date: 20140125