ZA200205482B - Aminosulfonylbiphenyl derivatives. - Google Patents

Aminosulfonylbiphenyl derivatives.

Info

Publication number
ZA200205482B
ZA200205482B ZA200205482A ZA200205482A ZA200205482B ZA 200205482 B ZA200205482 B ZA 200205482B ZA 200205482 A ZA200205482 A ZA 200205482A ZA 200205482 A ZA200205482 A ZA 200205482A ZA 200205482 B ZA200205482 B ZA 200205482B
Authority
ZA
South Africa
Prior art keywords
aminosulfonylbiphenyl
derivatives
aminosulfonylbiphenyl derivatives
Prior art date
Application number
ZA200205482A
Other languages
English (en)
Inventor
Dieter Dorsch
Werner Mederski
Sabine Bernotat-Danielowski
Johannes Gleitz
James Vickers
Horst Juraszyk
Christos Tsaklakidis
Guido Melzer
Christopher Barnes
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA200205482B publication Critical patent/ZA200205482B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46—Y being a hydrogen or a carbon atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA200205482A 2000-02-23 2002-07-09 Aminosulfonylbiphenyl derivatives. ZA200205482B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10008329A DE10008329A1 (de) 2000-02-23 2000-02-23 Aminosulfonylbiphenylderivate

Publications (1)

Publication Number Publication Date
ZA200205482B true ZA200205482B (en) 2003-12-31

Family

ID=7632028

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200205482A ZA200205482B (en) 2000-02-23 2002-07-09 Aminosulfonylbiphenyl derivatives.

Country Status (19)

Country Link
US (1) US20030135055A1 (es)
EP (1) EP1257530A1 (es)
JP (1) JP2003524651A (es)
KR (1) KR20020091092A (es)
CN (1) CN1404467A (es)
AU (1) AU2001254661A1 (es)
BR (1) BR0108607A (es)
CA (1) CA2399018A1 (es)
CZ (1) CZ20022783A3 (es)
DE (1) DE10008329A1 (es)
HK (1) HK1052499A1 (es)
HU (1) HUP0300008A2 (es)
MX (1) MXPA02008207A (es)
NO (1) NO20023998D0 (es)
PL (1) PL356565A1 (es)
RU (1) RU2002123337A (es)
SK (1) SK11992002A3 (es)
WO (1) WO2001062717A1 (es)
ZA (1) ZA200205482B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7030141B2 (en) 2001-11-29 2006-04-18 Christopher Franklin Bigge Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade
DE10204072A1 (de) * 2002-01-31 2003-08-14 Morphochem Ag Komb Chemie Neue Verbindungen, die Faktor Xa-Aktivität inhibieren
AU2004309357B2 (en) * 2003-12-22 2010-10-07 Merck Sharp & Dohme Corp. Alpha-hydroxy amides as bradykinin antagonists or inverse agonists
MX2007008290A (es) 2005-01-07 2008-02-15 Synta Pharmaceuticals Corp Compuestos para inflamacion y usos inmuno-relacionados.
WO2007087441A2 (en) 2006-01-25 2007-08-02 Synta Pharmaceuticals Corp. Substituted aromatic compounds for inflammation and immune-related uses
TW200806292A (en) 2006-01-25 2008-02-01 Synta Pharmaceuticals Corp Vinyl-phenyl derivatives for inflammation and immune-related uses
US8044242B2 (en) 2006-03-09 2011-10-25 Bristol-Myers Squibb Company 2-(aryloxy) acetamide factor VIIa inhibitors useful as anticoagulants
KR20090064478A (ko) 2006-11-13 2009-06-18 화이자 프로덕츠 인크. 디아릴, 디피리디닐 및 아릴-피리디닐 유도체, 및 이들의 용도
ES2494294T3 (es) 2007-02-09 2014-09-15 Metabasis Therapeutics, Inc. Antagonistas del receptor de glucagón
KR101599089B1 (ko) * 2008-08-13 2016-03-02 메타베이시스 테라퓨틱스, 인크. 글루카곤 길항제
EP3154956A4 (en) 2014-06-12 2018-01-17 Ligand Pharmaceuticals, Inc. Glucagon antagonists

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0946528B1 (en) * 1996-12-23 2003-04-09 Bristol-Myers Squibb Pharma Company OXYGEN OR SULFUR CONTAINING 5-MEMBERED HETEROAROMATICS AS FACTOR Xa INHIBITORS
KR20010082515A (ko) * 1998-02-17 2001-08-30 우에노 도시오 아미디노 유도체 및 그 유도체를 유효 성분으로서함유하는 약제
EP1189879A1 (en) * 1999-05-24 2002-03-27 Cor Therapeutics, Inc. INHIBITORS OF FACTOR Xa
CA2374793A1 (en) * 1999-05-24 2000-11-30 Penglie Zhang Inhibitors of factor xa

Also Published As

Publication number Publication date
NO20023998L (no) 2002-08-22
CA2399018A1 (en) 2001-08-30
CN1404467A (zh) 2003-03-19
HK1052499A1 (zh) 2003-09-19
PL356565A1 (en) 2004-06-28
NO20023998D0 (no) 2002-08-22
JP2003524651A (ja) 2003-08-19
AU2001254661A1 (en) 2001-09-03
KR20020091092A (ko) 2002-12-05
BR0108607A (pt) 2002-11-19
WO2001062717A1 (de) 2001-08-30
DE10008329A1 (de) 2001-08-30
US20030135055A1 (en) 2003-07-17
SK11992002A3 (sk) 2003-01-09
MXPA02008207A (es) 2002-11-29
HUP0300008A2 (hu) 2003-06-28
CZ20022783A3 (cs) 2002-11-13
EP1257530A1 (de) 2002-11-20
RU2002123337A (ru) 2004-01-10

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