ZA200203942B - Isoxazolecarboxamide derivatives. - Google Patents

Isoxazolecarboxamide derivatives. Download PDF

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Publication number
ZA200203942B
ZA200203942B ZA200203942A ZA200203942A ZA200203942B ZA 200203942 B ZA200203942 B ZA 200203942B ZA 200203942 A ZA200203942 A ZA 200203942A ZA 200203942 A ZA200203942 A ZA 200203942A ZA 200203942 B ZA200203942 B ZA 200203942B
Authority
ZA
South Africa
Prior art keywords
phenyl
carboxamide
piperazinyl
propyl
trifluoroethoxy
Prior art date
Application number
ZA200203942A
Other languages
English (en)
Inventor
Amedeo Leonardi
Gianni Motta
Elena Poggesi
Carlo Riva
Original Assignee
Recordati Chem Pharm
Chemical & Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm, Chemical & Pharmaceutical Co filed Critical Recordati Chem Pharm
Publication of ZA200203942B publication Critical patent/ZA200203942B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA200203942A 1999-10-18 2002-05-17 Isoxazolecarboxamide derivatives. ZA200203942B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999MI002173A IT1314191B1 (it) 1999-10-18 1999-10-18 Derivati isossazolcarbossamidici

Publications (1)

Publication Number Publication Date
ZA200203942B true ZA200203942B (en) 2003-01-02

Family

ID=11383797

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200203942A ZA200203942B (en) 1999-10-18 2002-05-17 Isoxazolecarboxamide derivatives.

Country Status (25)

Country Link
EP (1) EP1226131B1 (es)
JP (1) JP2003512362A (es)
KR (1) KR20020038944A (es)
CN (1) CN1139579C (es)
AR (1) AR029400A1 (es)
AT (1) ATE256670T1 (es)
AU (1) AU757614B2 (es)
BR (1) BR0014851A (es)
CA (1) CA2385472A1 (es)
DE (1) DE60007347T2 (es)
DK (1) DK1226131T3 (es)
ES (1) ES2210033T3 (es)
HK (1) HK1044940A1 (es)
HU (1) HUP0203184A3 (es)
IL (1) IL148837A0 (es)
IT (1) IT1314191B1 (es)
MX (1) MXPA02003432A (es)
MY (1) MY120400A (es)
NO (1) NO20021803L (es)
NZ (1) NZ517884A (es)
PL (1) PL356990A1 (es)
PT (1) PT1226131E (es)
RU (1) RU2002113096A (es)
WO (1) WO2001029015A2 (es)
ZA (1) ZA200203942B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101022082B1 (ko) 2005-10-11 2011-03-17 에프. 호프만-라 로슈 아게 아이소옥사졸 유도체
CA2628667A1 (en) 2005-11-09 2007-05-18 F. Hoffmann-La Roche Ag 3-aryl-isoxazole-4-carbonyl-benzofuran derivatives
JP5015172B2 (ja) 2005-12-23 2012-08-29 エフ.ホフマン−ラ ロシュ アーゲー アリール−イソオキサゾロ−4−イル−オキサジアゾール誘導体
PL1968973T3 (pl) 2005-12-27 2012-03-30 Hoffmann La Roche Pochodne aryloizoksazol-4-iloimidazolu
RU2426732C2 (ru) 2006-01-17 2011-08-20 Ф. Хоффманн-Ля Рош Аг АРИЛ-ИЗОКСАЗОЛ-4-ИЛ-ИМИДАЗО[1,2-a]ПИРИДИН, ПРИГОДНЫЙ ДЛЯ ЛЕЧЕНИЯ БОЛЕЗНИ АЛЬЦГЕЙМЕРА ЧЕРЕЗ ПОСРЕДСТВО GABA-РЕЦЕПТОРОВ
AU2007267183B2 (en) 2006-05-31 2011-10-20 F. Hoffmann-La Roche Ag Aryl-4-ethynyl-isoxazole derivatives
JP5416103B2 (ja) 2007-06-22 2014-02-12 エフ.ホフマン−ラ ロシュ アーゲー イソオキサゾール−イミダゾール誘導体
US7943619B2 (en) 2007-12-04 2011-05-17 Hoffmann-La Roche Inc. Isoxazolo-pyridazine derivatives
KR101175859B1 (ko) 2007-12-04 2012-08-24 에프. 호프만-라 로슈 아게 이속사졸로-피라진 유도체
US7902201B2 (en) 2007-12-04 2011-03-08 Hoffmann-La Roche Inc. Isoxazolo-pyrazine derivatives
WO2010081851A1 (en) 2009-01-14 2010-07-22 Genoscience Pharma Piperidin-4-ylpiperazine compounds for the treatment of hcv infection
TW201033201A (en) 2009-02-19 2010-09-16 Hoffmann La Roche Isoxazole-isoxazole and isoxazole-isothiazole derivatives
US8389550B2 (en) 2009-02-25 2013-03-05 Hoffmann-La Roche Inc. Isoxazoles / O-pyridines with ethyl and ethenyl linker
US8222246B2 (en) 2009-04-02 2012-07-17 Hoffmann-La Roche Inc. Substituted isoxazoles
US20100280019A1 (en) 2009-04-30 2010-11-04 Roland Jakob-Roetne Isoxazoles
MX2011011273A (es) 2009-05-05 2011-11-04 Hoffmann La Roche Derivados de isoxazol-pirazol.
US8410104B2 (en) 2009-05-05 2013-04-02 Hoffmann-La Roche Inc. Pyridazines
WO2010127976A1 (en) 2009-05-05 2010-11-11 F. Hoffmann-La Roche Ag Isoxazole-pyridine derivatives
JP5478716B2 (ja) 2009-05-05 2014-04-23 エフ.ホフマン−ラ ロシュ アーゲー 認識障害の処置において使用するためのgabaa受容体逆アゴニストとしてのイソオキサゾール−チアゾール誘導体
KR101354416B1 (ko) 2009-05-07 2014-02-19 에프. 호프만-라 로슈 아게 감마-아미노부티르산 조절제로서 이속사졸-피리딘 유도체
US8785435B2 (en) 2011-10-20 2014-07-22 Hoffmann-La Roche Inc. Solid forms
CN113121540B (zh) * 2020-01-15 2024-01-26 鲁南制药集团股份有限公司 一种西格列汀游离碱的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1254469B (it) * 1992-02-25 1995-09-25 Recordati Chem Pharm Derivati benzopiranici e benzotiopiranici
IT1266582B1 (it) * 1993-07-30 1997-01-09 Recordati Chem Pharm Derivati (di)azacicloesanici e diazacicloeptanici
DE4425146A1 (de) * 1994-07-15 1996-01-18 Basf Ag Verwendung heterocyclischer Verbindungen

Also Published As

Publication number Publication date
IT1314191B1 (it) 2002-12-06
DK1226131T3 (da) 2004-04-19
AU2834701A (en) 2001-04-30
KR20020038944A (ko) 2002-05-24
EP1226131A2 (en) 2002-07-31
AU757614B2 (en) 2003-02-27
NO20021803L (no) 2002-06-17
IL148837A0 (en) 2002-09-12
ES2210033T3 (es) 2004-07-01
PT1226131E (pt) 2004-05-31
HUP0203184A3 (en) 2004-12-28
HUP0203184A2 (hu) 2003-01-28
AR029400A1 (es) 2003-06-25
RU2002113096A (ru) 2003-11-10
CA2385472A1 (en) 2001-04-26
DE60007347D1 (de) 2004-01-29
CN1379767A (zh) 2002-11-13
JP2003512362A (ja) 2003-04-02
BR0014851A (pt) 2002-06-11
EP1226131B1 (en) 2003-12-17
HK1044940A1 (zh) 2002-11-08
WO2001029015A2 (en) 2001-04-26
NZ517884A (en) 2003-08-29
WO2001029015A3 (en) 2001-11-01
ATE256670T1 (de) 2004-01-15
ITMI992173A0 (it) 1999-10-18
MXPA02003432A (es) 2002-08-20
CN1139579C (zh) 2004-02-25
NO20021803D0 (no) 2002-04-17
DE60007347T2 (de) 2004-09-02
ITMI992173A1 (it) 2001-04-18
PL356990A1 (en) 2004-07-12
MY120400A (en) 2005-10-31

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