ZA200108527B - Preventives/remedies/progression inhibitors for simplex retinopathy or preproliferating retinopathy. - Google Patents

Preventives/remedies/progression inhibitors for simplex retinopathy or preproliferating retinopathy. Download PDF

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Publication number
ZA200108527B
ZA200108527B ZA200108527A ZA200108527A ZA200108527B ZA 200108527 B ZA200108527 B ZA 200108527B ZA 200108527 A ZA200108527 A ZA 200108527A ZA 200108527 A ZA200108527 A ZA 200108527A ZA 200108527 B ZA200108527 B ZA 200108527B
Authority
ZA
South Africa
Prior art keywords
compound
angiotensin
antagonistic activity
retinopathy
composition according
Prior art date
Application number
ZA200108527A
Other languages
English (en)
Inventor
Shizue Nakagawa
Yasutaka Nagisa
Hitoshi Ikeda
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ZA200108527B publication Critical patent/ZA200108527B/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200108527A 1999-04-28 2001-10-17 Preventives/remedies/progression inhibitors for simplex retinopathy or preproliferating retinopathy. ZA200108527B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12149899 1999-04-28

Publications (1)

Publication Number Publication Date
ZA200108527B true ZA200108527B (en) 2002-10-17

Family

ID=14812676

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200108527A ZA200108527B (en) 1999-04-28 2001-10-17 Preventives/remedies/progression inhibitors for simplex retinopathy or preproliferating retinopathy.

Country Status (23)

Country Link
US (2) US7064141B1 (cs)
EP (1) EP1197223B1 (cs)
KR (1) KR100865059B1 (cs)
CN (1) CN1172719C (cs)
AT (1) ATE289204T1 (cs)
AU (1) AU774799B2 (cs)
BR (1) BR0010084A (cs)
CA (1) CA2371554C (cs)
CZ (1) CZ301913B6 (cs)
DE (1) DE60018186T2 (cs)
DK (1) DK1197223T3 (cs)
ES (1) ES2233362T3 (cs)
HU (1) HU226948B1 (cs)
MX (1) MXPA01010923A (cs)
NO (1) NO327446B1 (cs)
NZ (1) NZ514855A (cs)
PL (1) PL196895B1 (cs)
PT (1) PT1197223E (cs)
RU (1) RU2239454C2 (cs)
SI (1) SI1197223T1 (cs)
SK (1) SK286859B6 (cs)
WO (1) WO2000066161A1 (cs)
ZA (1) ZA200108527B (cs)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1452176A4 (en) * 2001-12-03 2009-01-21 Takeda Pharmaceutical AGENTS FOR IMPROVING THE STATE OF RESISTANCE OF INSULIN
JP4484427B2 (ja) * 2001-12-03 2010-06-16 武田薬品工業株式会社 インスリン抵抗性改善剤
TW200304812A (en) * 2002-03-08 2003-10-16 Sankyo Co An eye drop containing a tetrazole derivative
US8980870B2 (en) 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations
DE10335027A1 (de) * 2003-07-31 2005-02-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verwendung von Angiotensin II Rezeptor Antagonisten
EP2517728B1 (en) * 2003-04-15 2015-01-28 Daiichi Sankyo Company, Limited Olmesartan medoxomil for preventing or treating angiogenic eye diseases
US20050038093A1 (en) * 2003-05-02 2005-02-17 Boehringer Ingelheim International Gmbh Treating diabetic retinopathy with angiotensin II receptor blockers
DK1784181T3 (da) 2004-08-31 2013-09-02 Newsouth Innovations Pty Ltd VEGF-hæmning
AU2005300787B2 (en) * 2004-11-05 2011-05-26 Boehringer Ingelheim International Gmbh Bilayer tablet comprising telmisartan and amlodipine
PT1872783E (pt) * 2005-04-21 2012-01-16 Santen Pharmaceutical Co Ltd Agente terapêutico para distúrbio queratoconjuntivo
CN101312962A (zh) * 2005-12-06 2008-11-26 参天制药株式会社 角膜结膜病变的治疗剂
EP2124903B1 (en) * 2007-03-28 2019-06-12 Takeda Pharmaceutical Company Limited Solid pharmaceutical composition comprising a benzimidazole-7-carboxylate derivative and a ph control agent

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9027211D0 (en) 1990-12-14 1991-02-06 Smithkline Beecham Plc Medicaments
US5614519A (en) 1991-02-06 1997-03-25 Karl Thomae Gmbh (1-(2,3 or 4-N-morpholinoalkyl)-imidazol-4-yl)-benizimidazol-1-yl-methyl]-biphenyls useful as angiotensin-II antagonists
DE4201554A1 (de) * 1992-01-22 1993-07-29 Thomae Gmbh Dr K Benzimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
GB9110635D0 (en) * 1991-05-16 1991-07-03 Glaxo Group Ltd Chemical compounds
IL104755A0 (en) * 1992-02-17 1993-06-10 Ciba Geigy Ag Treatment of glaucoma
GB9223860D0 (en) * 1992-11-13 1993-01-06 Glaxo Group Ltd Chemical compounds
CZ154994A3 (en) 1993-07-02 1995-09-13 Senju Pharma Co Visual hypotensive agent
JPH0789957A (ja) 1993-09-22 1995-04-04 Nissan Chem Ind Ltd ビフェニルメチルアミン誘導体
AU1423795A (en) 1994-02-08 1995-08-29 Novartis Ag Treatment of normotensive glaucoma with angiotensin ii antagonists
JPH09210183A (ja) * 1996-01-31 1997-08-12 Suzuki Motor Corp 動力伝達装置
HU228263B1 (en) * 1996-03-29 2013-02-28 Smithkline Beecham Corp Eprosartan dihydrate and a process for its production and formulation
PL193365B1 (pl) * 1996-04-05 2007-02-28 Takeda Pharmaceutical Kompozycja farmaceutyczna do zapobiegania lub zwalczania chorób związanych z angiotensyną II oraz zastosowanie związków do wytwarzania leku do zapobiegania lub zwalczania chorób związanych z angiotensyną II
TW416953B (en) 1996-09-25 2001-01-01 Takeda Chemical Industries Ltd Tricyclic compounds for eliciting a prostaglandin I2 receptor agonistic effect, their production and use
EP0855392A3 (de) 1997-01-22 2000-01-05 Hoechst Aktiengesellschaft Fünfgliedrige Heterocyclen mit Biphenylsulfonylsubstitution, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
WO1999000383A1 (en) * 1997-06-27 1999-01-07 Smithkline Beecham Corporation Eprosartan monohydrate
IT1292437B1 (it) * 1997-06-30 1999-02-08 Zambon Spa Processo di orto-metallazione utile per la sintesi di 1 - tetrazol- 5-il) benzeni 2-sostituiti
ES2273433T3 (es) * 1997-08-06 2007-05-01 Smithkline Beecham Corporation Complejo por neutralizacion de cargas con arginilo de eprosartan y procedimiento para su produccion y formulacion.
CN1291888A (zh) 1998-03-04 2001-04-18 武田药品工业株式会社 Aⅱ拮抗剂的缓释制剂、其制备和用途
CA2678722C (en) 1998-07-10 2013-08-27 Novartis Ag Antihypertensive combination of valsartan and a calcium channel blocker
FR2783422A1 (fr) 1998-09-21 2000-03-24 Sanofi Sa Composition pharmaceutique contenant un antagoniste des recepteurs at1 de l'angiotensine ii et un antiagregant plaquettaire
JP2000159671A (ja) 1998-12-01 2000-06-13 Takeda Chem Ind Ltd 血管新生阻害剤

Also Published As

Publication number Publication date
NO20015257L (no) 2001-10-26
PL350554A1 (en) 2002-12-16
EP1197223B1 (en) 2005-02-16
PT1197223E (pt) 2005-04-29
SK15452001A3 (sk) 2002-04-04
SK286859B6 (sk) 2009-06-05
HU226948B1 (en) 2010-03-29
EP1197223A1 (en) 2002-04-17
CZ301913B6 (cs) 2010-07-28
WO2000066161A1 (fr) 2000-11-09
EP1197223A4 (en) 2003-10-29
DE60018186T2 (de) 2005-12-29
NZ514855A (en) 2004-01-30
ATE289204T1 (de) 2005-03-15
RU2239454C2 (ru) 2004-11-10
AU774799B2 (en) 2004-07-08
AU4143400A (en) 2000-11-17
ES2233362T3 (es) 2005-06-16
PL196895B1 (pl) 2008-02-29
KR100865059B1 (ko) 2008-10-23
CN1172719C (zh) 2004-10-27
CN1348385A (zh) 2002-05-08
HUP0200890A3 (en) 2002-12-28
BR0010084A (pt) 2002-01-15
MXPA01010923A (es) 2002-06-21
CA2371554A1 (en) 2000-11-09
US7064141B1 (en) 2006-06-20
CZ20013804A3 (cs) 2002-04-17
KR20020015315A (ko) 2002-02-27
DK1197223T3 (da) 2005-05-30
DE60018186D1 (de) 2005-03-24
SI1197223T1 (cs) 2005-08-31
HUP0200890A2 (hu) 2002-11-28
CA2371554C (en) 2009-06-09
NO327446B1 (no) 2009-06-29
US20060189669A1 (en) 2006-08-24
NO20015257D0 (no) 2001-10-26

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