YU47580B - Postupak za dobijanje novih derivata benzonitrila - Google Patents
Postupak za dobijanje novih derivata benzonitrilaInfo
- Publication number
- YU47580B YU47580B YU234088A YU234088A YU47580B YU 47580 B YU47580 B YU 47580B YU 234088 A YU234088 A YU 234088A YU 234088 A YU234088 A YU 234088A YU 47580 B YU47580 B YU 47580B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- integer
- straight
- alkyl group
- carbon atoms
- group containing
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- JFDZBHWFFUWGJE-UHFFFAOYSA-N benzonitrile Chemical class N#CC1=CC=CC=C1 JFDZBHWFFUWGJE-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000001153 fluoro group Chemical group F* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 150000008359 benzonitriles Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/41—Y being a hydrogen or an acyclic carbon atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
POSTUPAK ZA DOBIJANJE NOVIH DERIVATA BENZONITRILA opšte formule u kojoj je n ceo broj 0, 1 ili 2, Y je CH2 m, CHOH, CHOCH3, CHNHR ili CHF, m je ceo broj 0 ili 1 i R je vodonik, metil ili etil, Z je vodonik ili zasićena ili nezasićena, prava ili račvasta alkil grupa koja sadrži 1-3 atoma ugljenika, A je grupa gde je Ra prava ili račvasta hidroksialkil ili alkil grupa koja sadrži 1-5 atoma ugljenika i opciono je supstituisana sa jednim ili više atoma fluora. Rc je zasićena ili nezasićena, prava ili račvasta alkil grupa koja sadrži 1-4 atoma ugljenika i opciono je supstituisana sa jednim ili više atoma fluora, Ra' je isti kao Ra i nezavisno od Ra" Ra" je isto kao Ra i nezavisno od Ra" p je ceo broj, 1 ili 2, s je ceo broj 2, 3, 4 ili 5 po potrebi u obliku racemske smeše ili u obliku steroizomerne komponente, i njihovih farmaceutski prihvatljivih soli, naznačen time, što obuhvata oksidaciju jedinjenja formule u kojoj Y, Z i A imaju gore data značenja, a p je jednako 0. Prijava sadrži još 10 zavisnih zahteva.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8705150A SE8705150D0 (sv) | 1987-12-23 | 1987-12-23 | Novel antiarrhythmic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU234088A YU234088A (en) | 1990-06-30 |
| YU47580B true YU47580B (sh) | 1995-10-24 |
Family
ID=20370706
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU234088A YU47580B (sh) | 1987-12-23 | 1988-12-23 | Postupak za dobijanje novih derivata benzonitrila |
| YU00196/90A YU19690A (en) | 1987-12-23 | 1990-02-02 | Process for obtaining new derivatives of benzonitryl |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU00196/90A YU19690A (en) | 1987-12-23 | 1990-02-02 | Process for obtaining new derivatives of benzonitryl |
Country Status (33)
| Country | Link |
|---|---|
| US (2) | US5034411A (sh) |
| EP (2) | EP0322390B1 (sh) |
| JP (2) | JPH0637458B2 (sh) |
| KR (2) | KR900700441A (sh) |
| CN (3) | CN1033804A (sh) |
| AR (1) | AR247729A1 (sh) |
| AT (2) | ATE81848T1 (sh) |
| AU (4) | AU625872B2 (sh) |
| DD (2) | DD277274A5 (sh) |
| DE (2) | DE3875600T2 (sh) |
| DK (2) | DK404889A (sh) |
| EG (1) | EG18681A (sh) |
| ES (2) | ES2045189T3 (sh) |
| FI (2) | FI92192C (sh) |
| GR (2) | GR3006241T3 (sh) |
| HU (3) | HUT54346A (sh) |
| IE (2) | IE883860L (sh) |
| IL (2) | IL103741A (sh) |
| IS (1) | IS1558B (sh) |
| LT (4) | LTIP1688A (sh) |
| LV (1) | LV10250A (sh) |
| MX (1) | MX174084B (sh) |
| MY (1) | MY103945A (sh) |
| NO (2) | NO171724C (sh) |
| NZ (1) | NZ227381A (sh) |
| PH (2) | PH26828A (sh) |
| PL (2) | PL157747B1 (sh) |
| PT (2) | PT89311B (sh) |
| RU (3) | RU2024503C1 (sh) |
| SE (1) | SE8705150D0 (sh) |
| WO (3) | WO1989005794A1 (sh) |
| YU (2) | YU47580B (sh) |
| ZA (2) | ZA889424B (sh) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8705150D0 (sv) * | 1987-12-23 | 1987-12-23 | Haessle Ab | Novel antiarrhythmic agents |
| SE9003902D0 (sv) * | 1990-12-07 | 1990-12-07 | Astra Ab | Solid dosage forms of a drug |
| SE8902236D0 (sv) * | 1989-06-20 | 1989-06-20 | Haessle Ab | Novel polystyrenesulfonate |
| SE8902235D0 (sv) * | 1989-06-20 | 1989-06-20 | Haessle Ab | Novel cyclodextrin inclusion complexes |
| SE8902237D0 (sv) * | 1989-06-20 | 1989-06-20 | Haessle Ab | Novel stereoisomers |
| US5084463A (en) * | 1989-12-11 | 1992-01-28 | American Home Products Corporation | N-quinolinyl alkyl-substituted 1-aryloxy-2-propanolamine and propylamine derivatives possessing class III antiarrhythmic activity |
| US5619274A (en) * | 1990-09-10 | 1997-04-08 | Starsight Telecast, Inc. | Television schedule information transmission and utilization system and process |
| UA26190C2 (uk) * | 1992-07-28 | 1999-07-19 | Сейфтек Ай Лімітед | Шприц |
| US5679706A (en) * | 1994-09-30 | 1997-10-21 | Bristol-Myers Squibb Company | Combination of a potassium channel activator and an antiarrhythmic agent |
| US6143569A (en) * | 1998-08-31 | 2000-11-07 | The United States Of America As Represented By The Secretary Of The Navy | Chelators exhibiting triple fluorescence |
| GB0123961D0 (en) * | 2001-10-05 | 2001-11-28 | Astrazeneca Ab | Process and intermediates |
| WO2004113305A2 (en) | 2003-06-16 | 2004-12-29 | Vertex Pharmaceuticals Incorporated | Diamino substituted quinazoline derivatives as promoters of smn2 |
| WO2005007215A2 (en) * | 2003-07-09 | 2005-01-27 | Glucolight Corporation | Method and apparatus for tissue oximetry |
| RU2631231C1 (ru) * | 2016-12-01 | 2017-09-19 | Научно-производственная ассоциация "Технопарк Авиационных Технологий" | Способ получения заготовки лопатки газотурбинного двигателя для линейной сварки трением |
| CN115417973B (zh) * | 2022-11-03 | 2023-03-24 | 广东粤港澳大湾区黄埔材料研究院 | 抗菌聚氨酯材料及其制备方法和应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3149147A (en) * | 1961-03-16 | 1964-09-15 | Smith Kline French Lab | Novel substituted phenylalkylamines |
| FR152F (sh) * | 1962-01-24 | |||
| GB1069345A (en) * | 1963-07-19 | 1967-05-17 | Ici Ltd | New alkanolamine derivatives |
| DE1593771A1 (de) * | 1967-04-06 | 1970-04-30 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von 1-Phenoxy-2-amino-alkanen |
| BE757005A (fr) * | 1969-10-02 | 1971-04-02 | Bristol Myers Co | Phenethanolamines substituees et procede pour leur preparation |
| GB1457876A (en) * | 1972-12-15 | 1976-12-08 | Ici Ltd | Alkanolamine derivatives device for use in |
| SE404793B (sv) * | 1973-05-25 | 1978-10-30 | Boehringer Sohn Ingelheim | Forfarande for framstellning av vissa angivna nitrilsubstituerade 1-fenoxi-2-hydroxi-3-lagalkylaminopropaner |
| GB1433920A (en) * | 1973-10-01 | 1976-04-28 | Ici Ltd | Alkanolamine derivatives |
| FR2280376A1 (fr) * | 1974-08-02 | 1976-02-27 | Sogeras | Nouveaux derives du piperidine-4 ethanol |
| DE2503222A1 (de) * | 1975-01-27 | 1976-07-29 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten |
| SE421123B (sv) * | 1976-08-25 | 1981-11-30 | Boehringer Sohn Ingelheim | Forfarande for framstellning av vissa angivna nitrilsubstituerade 1-fenoxi-2-hydroxi-3-alkylaminopropaner |
| US4283534A (en) * | 1979-04-11 | 1981-08-11 | Basf Aktiengesellschaft | Reductive alkylation of nitrogen heterocycles |
| US4544654A (en) * | 1984-03-20 | 1985-10-01 | Schering A.G. | Substituted sulfonamidobenzamides, antiarrhythmic agents and compositions thereof |
| US4614746A (en) * | 1985-03-21 | 1986-09-30 | American Cyanamid Company | 5-fluorobenzonitrile derivatives for increasing the lean meat to fat ratio and/or enhancing the growth rate of warm-blooded animals |
| FI862343A (fi) * | 1985-06-17 | 1986-12-18 | Warner Lambert Co | Foerfarande foer framstaellning av terapeutiskt verkande 1,4-dihydropyridinfoereningar. |
| EG18188A (en) * | 1986-05-01 | 1992-09-30 | Pfizer Ltd | Process for preparation anti-arhythmia agents |
| SE8705150D0 (sv) * | 1987-12-23 | 1987-12-23 | Haessle Ab | Novel antiarrhythmic agents |
| SE8902237D0 (sv) * | 1989-06-20 | 1989-06-20 | Haessle Ab | Novel stereoisomers |
| SE8902236D0 (sv) * | 1989-06-20 | 1989-06-20 | Haessle Ab | Novel polystyrenesulfonate |
-
1987
- 1987-12-23 SE SE8705150A patent/SE8705150D0/xx unknown
-
1988
- 1988-12-15 ZA ZA889424A patent/ZA889424B/xx unknown
- 1988-12-19 NZ NZ227381A patent/NZ227381A/en unknown
- 1988-12-20 JP JP50046888A patent/JPH0637458B2/ja not_active Expired - Lifetime
- 1988-12-20 AU AU28241/89A patent/AU625872B2/en not_active Ceased
- 1988-12-20 AT AT88850427T patent/ATE81848T1/de not_active IP Right Cessation
- 1988-12-20 WO PCT/SE1988/000691 patent/WO1989005794A1/en active IP Right Grant
- 1988-12-20 AU AU28244/89A patent/AU625774B2/en not_active Ceased
- 1988-12-20 AT AT88850428T patent/ATE82257T1/de not_active IP Right Cessation
- 1988-12-20 ES ES88850428T patent/ES2045189T3/es not_active Expired - Lifetime
- 1988-12-20 WO PCT/SE1988/000692 patent/WO1989005795A1/en active Application Filing
- 1988-12-20 AU AU28244/89A patent/AU2824489A/en active Granted
- 1988-12-20 HU HU89361A patent/HUT54346A/hu unknown
- 1988-12-20 HU HU913679A patent/HU913679D0/hu unknown
- 1988-12-20 HU HU89359A patent/HU205895B/hu not_active IP Right Cessation
- 1988-12-20 ES ES88850427T patent/ES2043891T3/es not_active Expired - Lifetime
- 1988-12-20 DE DE8888850427T patent/DE3875600T2/de not_active Expired - Fee Related
- 1988-12-20 JP JP1500469A patent/JPH02502726A/ja active Pending
- 1988-12-20 EP EP88850428A patent/EP0322390B1/en not_active Expired - Lifetime
- 1988-12-20 DE DE8888850428T patent/DE3875934T2/de not_active Expired - Fee Related
- 1988-12-20 EP EP88850427A patent/EP0322389B1/en not_active Expired - Lifetime
- 1988-12-21 IS IS3425A patent/IS1558B/is unknown
- 1988-12-21 IL IL10374188A patent/IL103741A/en not_active IP Right Cessation
- 1988-12-21 PH PH37960A patent/PH26828A/en unknown
- 1988-12-21 PH PH37959A patent/PH25526A/en unknown
- 1988-12-21 IL IL8874988A patent/IL88749A/en not_active IP Right Cessation
- 1988-12-22 MX MX014310A patent/MX174084B/es unknown
- 1988-12-22 AR AR88312835A patent/AR247729A1/es active
- 1988-12-22 IE IE883860A patent/IE883860L/xx unknown
- 1988-12-22 PT PT89311A patent/PT89311B/pt not_active IP Right Cessation
- 1988-12-22 WO PCT/SE1988/000697 patent/WO1989005806A1/en unknown
- 1988-12-22 PT PT89312A patent/PT89312B/pt not_active IP Right Cessation
- 1988-12-22 MY MYPI88001510A patent/MY103945A/en unknown
- 1988-12-22 IE IE883859A patent/IE883859L/xx unknown
- 1988-12-22 EG EG653/88A patent/EG18681A/xx active
- 1988-12-22 US US07/289,630 patent/US5034411A/en not_active Expired - Fee Related
- 1988-12-22 AU AU29103/89A patent/AU2910389A/en not_active Abandoned
- 1988-12-23 YU YU234088A patent/YU47580B/sh unknown
- 1988-12-23 PL PL1988276698A patent/PL157747B1/pl unknown
- 1988-12-23 CN CN88108941A patent/CN1033804A/zh active Pending
- 1988-12-23 PL PL1988287936A patent/PL159551B1/pl unknown
- 1988-12-28 DD DD88324296A patent/DD277274A5/de not_active IP Right Cessation
-
1989
- 1989-06-12 ZA ZA894441A patent/ZA894441B/xx unknown
- 1989-06-19 DD DD89329730A patent/DD295353A5/de not_active IP Right Cessation
- 1989-06-22 CN CN89104335A patent/CN1048214A/zh active Pending
- 1989-08-17 DK DK404889A patent/DK404889A/da unknown
- 1989-08-17 DK DK404789A patent/DK404789A/da not_active Application Discontinuation
- 1989-08-22 RU SU894614813A patent/RU2024503C1/ru active
- 1989-08-22 KR KR1019890701579A patent/KR900700441A/ko not_active Application Discontinuation
- 1989-08-22 FI FI893936A patent/FI92192C/sv not_active IP Right Cessation
- 1989-08-22 NO NO893375A patent/NO171724C/no unknown
- 1989-08-22 NO NO893376A patent/NO171784C/no unknown
- 1989-08-22 FI FI893937A patent/FI893937A/fi not_active Application Discontinuation
- 1989-08-22 RU SU894614909A patent/RU1836342C/ru active
- 1989-08-23 KR KR1019890701592A patent/KR900700442A/ko not_active Application Discontinuation
-
1990
- 1990-02-02 YU YU00196/90A patent/YU19690A/xx unknown
-
1991
- 1991-01-18 US US07/643,161 patent/US5155133A/en not_active Expired - Fee Related
- 1991-04-22 RU SU914895329A patent/RU1836343C/ru active
-
1992
- 1992-11-12 GR GR920402579T patent/GR3006241T3/el unknown
-
1993
- 1993-01-28 GR GR930400159T patent/GR3006912T3/el unknown
- 1993-06-30 LV LV930851A patent/LV10250A/xx unknown
- 1993-12-28 LT LTIP1688A patent/LTIP1688A/xx not_active Application Discontinuation
- 1993-12-28 LT LTIP1687A patent/LTIP1687A/xx not_active Application Discontinuation
- 1993-12-30 LT LTIP1720A patent/LTIP1720A/xx not_active Application Discontinuation
- 1993-12-31 LT LTIP1752A patent/LTIP1752A/xx not_active Application Discontinuation
-
1994
- 1994-05-31 CN CN94105497A patent/CN1097736A/zh active Pending
Also Published As
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