GB1457876A - Alkanolamine derivatives device for use in - Google Patents

Alkanolamine derivatives device for use in

Info

Publication number
GB1457876A
GB1457876A GB5751773A GB5751773A GB1457876A GB 1457876 A GB1457876 A GB 1457876A GB 5751773 A GB5751773 A GB 5751773A GB 5751773 A GB5751773 A GB 5751773A GB 1457876 A GB1457876 A GB 1457876A
Authority
GB
United Kingdom
Prior art keywords
propanol
phenoxy
alkanolamine derivatives
derivatives
ssisobutyramidoethylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5751773A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB4347873A external-priority patent/GB1455116A/en
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Priority to GB5751773A priority Critical patent/GB1457876A/en
Priority to FI1764/74A priority patent/FI65987C/en
Priority to SE7407702A priority patent/SE417198B/en
Priority to DK311174A priority patent/DK311174A/da
Priority to NO742118A priority patent/NO140496C/en
Priority to US05/526,921 priority patent/US3959369A/en
Priority to IE2438/74A priority patent/IE40267B1/en
Priority to ZA00747665A priority patent/ZA747665B/en
Priority to CA215,068A priority patent/CA1034591A/en
Priority to IN2679/CAL/74A priority patent/IN141235B/en
Priority to IL46183A priority patent/IL46183A/en
Priority to AU76205/74A priority patent/AU487577B2/en
Priority to MW48/74A priority patent/MW4874A1/en
Priority to LU71449A priority patent/LU71449A1/xx
Priority to BE151408A priority patent/BE823238R/en
Priority to NL7416114A priority patent/NL7416114A/en
Priority to DE19742458908 priority patent/DE2458908C2/en
Priority to ES432848A priority patent/ES432848A2/en
Priority to YU03299/74A priority patent/YU329974A/en
Priority to CH1657074A priority patent/CH614925A5/en
Priority to DD182977A priority patent/DD119416A6/xx
Priority to JP49143019A priority patent/JPS5089334A/ja
Priority to FR7441011A priority patent/FR2254325B2/fr
Priority to ZM775A priority patent/ZM775A1/en
Priority to US05/664,044 priority patent/US4041075A/en
Publication of GB1457876A publication Critical patent/GB1457876A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/06—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton
    • C07C275/14—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an acyclic and saturated carbon skeleton being further substituted by nitrogen atoms not being part of nitro or nitroso groups

Abstract

Novel 1-amidoaryloxy-3-amidoalkylamino-2-propanol derivatives of the formula: <IMAGE> wherein the symbols have the meanings given in the Patent Claim, for example 1-o-(N-ss-hydroxyethylcarbamoylmethoxy)-phenoxy-3-ssisobutyramidoethylamino-2-propanol, are prepared by reacting an appropriate 2,3-epoxy-1-phenoxypropane or a 3-halogeno-1-phenoxy-2-propanol with an amine HNR<6>-A-NR<7>-XYR<1>. The compounds exert a blocking action on the adrenergic ss-receptors and can be used for the treatment of cardiac disorders.
GB5751773A 1972-12-15 1973-12-12 Alkanolamine derivatives device for use in Expired GB1457876A (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
GB5751773A GB1457876A (en) 1972-12-15 1973-12-12 Alkanolamine derivatives device for use in
FI1764/74A FI65987C (en) 1973-12-12 1974-06-10 FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA ALKANOLAMINDERIVAT
SE7407702A SE417198B (en) 1972-12-15 1974-06-11 ANALOGY PROCEDURE FOR PREPARING ALKANOLAMINE DERIVATIVES
DK311174A DK311174A (en) 1973-12-12 1974-06-11
NO742118A NO140496C (en) 1973-12-12 1974-06-11 ANALOGICAL PROCEDURE FOR THE PREPARATION OF PHYSIOLOGICALLY ACTIVE ALKANOLAMINES
US05/526,921 US3959369A (en) 1973-12-12 1974-11-25 Alkanolamine derivatives
IE2438/74A IE40267B1 (en) 1973-12-12 1974-11-27 Alkanolamine derivatives
ZA00747665A ZA747665B (en) 1973-12-12 1974-12-02 Alkanolamine derivatives
CA215,068A CA1034591A (en) 1973-12-12 1974-12-02 Alkanolamine derivatives
IN2679/CAL/74A IN141235B (en) 1973-12-06 1974-12-04
IL46183A IL46183A (en) 1973-12-12 1974-12-04 3-aminoalkylamino-1-phenoxy-2propanol derivatives,their preparation and pharmaceutical compositions comprising them
AU76205/74A AU487577B2 (en) 1973-12-12 1974-12-09 Alkanolamine derivatives
MW48/74A MW4874A1 (en) 1973-12-12 1974-12-09 Alkanolamine derivatives
LU71449A LU71449A1 (en) 1972-12-15 1974-12-10
NL7416114A NL7416114A (en) 1972-12-15 1974-12-11 ALKANOLAMINE DERIVATIVES AND METHODS FOR PREPARING AND APPLYING THEM.
BE151408A BE823238R (en) 1973-12-12 1974-12-11 ALKANOLAMINES
FR7441011A FR2254325B2 (en) 1972-12-15 1974-12-12
DD182977A DD119416A6 (en) 1973-12-12 1974-12-12
ES432848A ES432848A2 (en) 1973-12-12 1974-12-12 Alkanolamine derivatives
YU03299/74A YU329974A (en) 1973-12-12 1974-12-12 Process for preparing alkanol amine derivatives
CH1657074A CH614925A5 (en) 1972-12-15 1974-12-12 Process for the preparation of alkanolamine derivatives
DE19742458908 DE2458908C2 (en) 1972-12-15 1974-12-12 Alkanolamine derivatives and pharmaceutical compositions containing them
JP49143019A JPS5089334A (en) 1973-12-12 1974-12-12
ZM775A ZM775A1 (en) 1973-12-12 1975-01-16 Alkanolamine derivatives
US05/664,044 US4041075A (en) 1973-12-12 1976-03-04 Phenoxy-alkanolamine derivatives

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB5797072 1972-12-15
GB4347873A GB1455116A (en) 1972-12-15 1973-09-17 Pharmaceutical compositions
GB5751773A GB1457876A (en) 1972-12-15 1973-12-12 Alkanolamine derivatives device for use in

Publications (1)

Publication Number Publication Date
GB1457876A true GB1457876A (en) 1976-12-08

Family

ID=27259797

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5751773A Expired GB1457876A (en) 1972-12-15 1973-12-12 Alkanolamine derivatives device for use in

Country Status (7)

Country Link
CH (1) CH614925A5 (en)
DE (1) DE2458908C2 (en)
FR (1) FR2254325B2 (en)
GB (1) GB1457876A (en)
LU (1) LU71449A1 (en)
NL (1) NL7416114A (en)
SE (1) SE417198B (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0322390A2 (en) * 1987-12-23 1989-06-28 Aktiebolaget Hässle Novel antiarrhythmic agents I
WO1990015792A1 (en) * 1989-06-20 1990-12-27 Aktiebolaget Hässle Novel cyclodextrin inclusion complexes
EP0404747A1 (en) * 1989-06-20 1990-12-27 Aktiebolaget Hässle Novel polystyrenesulfonate
EP0404748A1 (en) * 1989-06-20 1990-12-27 Aktiebolaget Hässle Novel stereoisomers
US5043444A (en) * 1989-07-28 1991-08-27 Chemie Linz Gesellschaft M.B.H. Process for the preparation of asymmetrically substituted ureas
US5149523A (en) * 1989-06-20 1992-09-22 Aktiebolaget Hassle Polystyrenesulfonate-drug complex and solid dosage forms thereof

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1540463A (en) * 1976-10-07 1979-02-14 Ici Ltd Alkanolamine derivatives
FI76551C (en) * 1980-11-06 1988-11-10 Sandoz Ag FOERFARANDE FOER FRAMSTAELLNING AV NYA TERAPEUTISKT ANVAENDBARA 3-AMINOPROPOXIFENYLDERIVAT.
ATE19510T1 (en) * 1981-12-17 1986-05-15 Haessle Ab PARA-SUBSTITUTED 3-PHENOXY-1CARBONYLAMINOALKYLAMINOPROPAN-2-OLS WITH BLOCKING EFFECTS ON BETA-RECEPTORS.

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034411A (en) * 1987-12-23 1991-07-23 Aktiebolaget Hassle Novel 4-cyanophenyl derivatives with action against cardiac arrhythmia
EP0322390A2 (en) * 1987-12-23 1989-06-28 Aktiebolaget Hässle Novel antiarrhythmic agents I
WO1989005795A1 (en) * 1987-12-23 1989-06-29 Aktiebolaget Hässle Novel antiarrhythmic agents ii
WO1989005806A1 (en) * 1987-12-23 1989-06-29 Ab Hässle Novel antiarrhythmic agents iii
US5155133A (en) * 1987-12-23 1992-10-13 Aktiebolaget Hassle Antiarrhythmic compounds and pharmaceutical compositions and methods thereof
EP0322390A3 (en) * 1987-12-23 1989-09-06 Aktiebolaget Hassle Novel antiarrhythmic agents i
EP0322389A2 (en) * 1987-12-23 1989-06-28 Aktiebolaget Hässle Novel antiarrhythmic agents II
EP0322389A3 (en) * 1987-12-23 1989-09-06 Aktiebolaget Hassle Novel antiarrhythmic agents ii
WO1989005794A1 (en) * 1987-12-23 1989-06-29 Aktiebolaget Hässle Novel antiarrhythmic agents i
EP0404747A1 (en) * 1989-06-20 1990-12-27 Aktiebolaget Hässle Novel polystyrenesulfonate
WO1990015794A1 (en) * 1989-06-20 1990-12-27 Aktiebolaget Hässle Novel stereoisomers
WO1990015793A1 (en) * 1989-06-20 1990-12-27 Aktiebolaget Hässle Novel polystyrenesulfonate
EP0404748A1 (en) * 1989-06-20 1990-12-27 Aktiebolaget Hässle Novel stereoisomers
US5149523A (en) * 1989-06-20 1992-09-22 Aktiebolaget Hassle Polystyrenesulfonate-drug complex and solid dosage forms thereof
WO1990015792A1 (en) * 1989-06-20 1990-12-27 Aktiebolaget Hässle Novel cyclodextrin inclusion complexes
US5043444A (en) * 1989-07-28 1991-08-27 Chemie Linz Gesellschaft M.B.H. Process for the preparation of asymmetrically substituted ureas

Also Published As

Publication number Publication date
CH614925A5 (en) 1979-12-28
SE7407702L (en) 1975-06-13
FR2254325B2 (en) 1977-11-25
LU71449A1 (en) 1976-04-13
FR2254325A2 (en) 1975-07-11
SE417198B (en) 1981-03-02
DE2458908C2 (en) 1983-12-08
NL7416114A (en) 1975-06-16
DE2458908A1 (en) 1975-09-11

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