PT89311A - Processo para a preparacao de novos aminoalcoxi-p-benzonitrilos substituidos utilizaveis como agentes antiarritmicos e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de novos aminoalcoxi-p-benzonitrilos substituidos utilizaveis como agentes antiarritmicos e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT89311A PT89311A PT89311A PT8931188A PT89311A PT 89311 A PT89311 A PT 89311A PT 89311 A PT89311 A PT 89311A PT 8931188 A PT8931188 A PT 8931188A PT 89311 A PT89311 A PT 89311A
- Authority
- PT
- Portugal
- Prior art keywords
- arithital
- aminoalcoxy
- benzonitrils
- agents
- preparation
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/24—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/25—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/41—Y being a hydrogen or an acyclic carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8705150A SE8705150D0 (sv) | 1987-12-23 | 1987-12-23 | Novel antiarrhythmic agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT89311A true PT89311A (pt) | 1989-12-29 |
| PT89311B PT89311B (pt) | 1993-08-31 |
Family
ID=20370706
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT89312A PT89312B (pt) | 1987-12-23 | 1988-12-22 | Processo para a preparacao de novos benzonitrilos substituidos na posicao para utilizaveis como agentes antiarritmicos e de composicoes farmaceuticas que os contem |
| PT89311A PT89311B (pt) | 1987-12-23 | 1988-12-22 | Processo para a preparacao de novos aminoalcoxi-p-benzonitrilos substituidos utilizaveis como agentes antiarritmicos e de composicoes farmaceuticas que os contem |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT89312A PT89312B (pt) | 1987-12-23 | 1988-12-22 | Processo para a preparacao de novos benzonitrilos substituidos na posicao para utilizaveis como agentes antiarritmicos e de composicoes farmaceuticas que os contem |
Country Status (33)
| Country | Link |
|---|---|
| US (2) | US5034411A (pt) |
| EP (2) | EP0322390B1 (pt) |
| JP (2) | JPH0637458B2 (pt) |
| KR (2) | KR900700441A (pt) |
| CN (3) | CN1033804A (pt) |
| AR (1) | AR247729A1 (pt) |
| AT (2) | ATE82257T1 (pt) |
| AU (4) | AU625774B2 (pt) |
| DD (2) | DD277274A5 (pt) |
| DE (2) | DE3875934T2 (pt) |
| DK (2) | DK404789A (pt) |
| EG (1) | EG18681A (pt) |
| ES (2) | ES2045189T3 (pt) |
| FI (2) | FI893937A (pt) |
| GR (2) | GR3006241T3 (pt) |
| HU (3) | HUT54346A (pt) |
| IE (2) | IE883860L (pt) |
| IL (2) | IL103741A (pt) |
| IS (1) | IS1558B (pt) |
| LT (4) | LTIP1687A (pt) |
| LV (1) | LV10250A (pt) |
| MX (1) | MX174084B (pt) |
| MY (1) | MY103945A (pt) |
| NO (2) | NO171784C (pt) |
| NZ (1) | NZ227381A (pt) |
| PH (2) | PH26828A (pt) |
| PL (2) | PL159551B1 (pt) |
| PT (2) | PT89312B (pt) |
| RU (3) | RU2024503C1 (pt) |
| SE (1) | SE8705150D0 (pt) |
| WO (3) | WO1989005794A1 (pt) |
| YU (2) | YU47580B (pt) |
| ZA (2) | ZA889424B (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8705150D0 (sv) * | 1987-12-23 | 1987-12-23 | Haessle Ab | Novel antiarrhythmic agents |
| SE9003902D0 (sv) * | 1990-12-07 | 1990-12-07 | Astra Ab | Solid dosage forms of a drug |
| SE8902237D0 (sv) * | 1989-06-20 | 1989-06-20 | Haessle Ab | Novel stereoisomers |
| SE8902235D0 (sv) * | 1989-06-20 | 1989-06-20 | Haessle Ab | Novel cyclodextrin inclusion complexes |
| SE8902236D0 (sv) * | 1989-06-20 | 1989-06-20 | Haessle Ab | Novel polystyrenesulfonate |
| US5084463A (en) * | 1989-12-11 | 1992-01-28 | American Home Products Corporation | N-quinolinyl alkyl-substituted 1-aryloxy-2-propanolamine and propylamine derivatives possessing class III antiarrhythmic activity |
| US5619274A (en) * | 1990-09-10 | 1997-04-08 | Starsight Telecast, Inc. | Television schedule information transmission and utilization system and process |
| UA26190C2 (uk) * | 1992-07-28 | 1999-07-19 | Сейфтек Ай Лімітед | Шприц |
| US5679706A (en) * | 1994-09-30 | 1997-10-21 | Bristol-Myers Squibb Company | Combination of a potassium channel activator and an antiarrhythmic agent |
| US6143569A (en) * | 1998-08-31 | 2000-11-07 | The United States Of America As Represented By The Secretary Of The Navy | Chelators exhibiting triple fluorescence |
| GB0123961D0 (en) * | 2001-10-05 | 2001-11-28 | Astrazeneca Ab | Process and intermediates |
| US7465738B2 (en) | 2003-06-16 | 2008-12-16 | Vertex Pharmaceuticals Incorporated | Compounds useful as promoters of SMN2 |
| US7356365B2 (en) * | 2003-07-09 | 2008-04-08 | Glucolight Corporation | Method and apparatus for tissue oximetry |
| RU2631231C1 (ru) * | 2016-12-01 | 2017-09-19 | Научно-производственная ассоциация "Технопарк Авиационных Технологий" | Способ получения заготовки лопатки газотурбинного двигателя для линейной сварки трением |
| CN115417973B (zh) * | 2022-11-03 | 2023-03-24 | 广东粤港澳大湾区黄埔材料研究院 | 抗菌聚氨酯材料及其制备方法和应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3149147A (en) * | 1961-03-16 | 1964-09-15 | Smith Kline French Lab | Novel substituted phenylalkylamines |
| FR152F (pt) * | 1962-01-24 | |||
| GB1069345A (en) * | 1963-07-19 | 1967-05-17 | Ici Ltd | New alkanolamine derivatives |
| DE1593771A1 (de) * | 1967-04-06 | 1970-04-30 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung von 1-Phenoxy-2-amino-alkanen |
| BE757005A (fr) * | 1969-10-02 | 1971-04-02 | Bristol Myers Co | Phenethanolamines substituees et procede pour leur preparation |
| GB1457876A (en) * | 1972-12-15 | 1976-12-08 | Ici Ltd | Alkanolamine derivatives device for use in |
| SE404793B (sv) * | 1973-05-25 | 1978-10-30 | Boehringer Sohn Ingelheim | Forfarande for framstellning av vissa angivna nitrilsubstituerade 1-fenoxi-2-hydroxi-3-lagalkylaminopropaner |
| GB1433920A (en) * | 1973-10-01 | 1976-04-28 | Ici Ltd | Alkanolamine derivatives |
| FR2280376A1 (fr) * | 1974-08-02 | 1976-02-27 | Sogeras | Nouveaux derives du piperidine-4 ethanol |
| DE2503222A1 (de) * | 1975-01-27 | 1976-07-29 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten |
| SE421123B (sv) * | 1976-08-25 | 1981-11-30 | Boehringer Sohn Ingelheim | Forfarande for framstellning av vissa angivna nitrilsubstituerade 1-fenoxi-2-hydroxi-3-alkylaminopropaner |
| US4283534A (en) * | 1979-04-11 | 1981-08-11 | Basf Aktiengesellschaft | Reductive alkylation of nitrogen heterocycles |
| US4544654A (en) * | 1984-03-20 | 1985-10-01 | Schering A.G. | Substituted sulfonamidobenzamides, antiarrhythmic agents and compositions thereof |
| US4614746A (en) * | 1985-03-21 | 1986-09-30 | American Cyanamid Company | 5-fluorobenzonitrile derivatives for increasing the lean meat to fat ratio and/or enhancing the growth rate of warm-blooded animals |
| FI862343A (fi) * | 1985-06-17 | 1986-12-18 | Warner Lambert Co | Foerfarande foer framstaellning av terapeutiskt verkande 1,4-dihydropyridinfoereningar. |
| EG18188A (en) * | 1986-05-01 | 1992-09-30 | Pfizer Ltd | Process for preparation anti-arhythmia agents |
| SE8705150D0 (sv) * | 1987-12-23 | 1987-12-23 | Haessle Ab | Novel antiarrhythmic agents |
| SE8902237D0 (sv) * | 1989-06-20 | 1989-06-20 | Haessle Ab | Novel stereoisomers |
| SE8902236D0 (sv) * | 1989-06-20 | 1989-06-20 | Haessle Ab | Novel polystyrenesulfonate |
-
1987
- 1987-12-23 SE SE8705150A patent/SE8705150D0/xx unknown
-
1988
- 1988-12-15 ZA ZA889424A patent/ZA889424B/xx unknown
- 1988-12-19 NZ NZ227381A patent/NZ227381A/en unknown
- 1988-12-20 AT AT88850428T patent/ATE82257T1/de not_active IP Right Cessation
- 1988-12-20 AU AU28244/89A patent/AU625774B2/en not_active Ceased
- 1988-12-20 AU AU28241/89A patent/AU625872B2/en not_active Ceased
- 1988-12-20 ES ES88850428T patent/ES2045189T3/es not_active Expired - Lifetime
- 1988-12-20 HU HU89361A patent/HUT54346A/hu unknown
- 1988-12-20 HU HU913679A patent/HU913679D0/hu unknown
- 1988-12-20 JP JP50046888A patent/JPH0637458B2/ja not_active Expired - Lifetime
- 1988-12-20 EP EP88850428A patent/EP0322390B1/en not_active Expired - Lifetime
- 1988-12-20 JP JP1500469A patent/JPH02502726A/ja active Pending
- 1988-12-20 DE DE8888850428T patent/DE3875934T2/de not_active Expired - Fee Related
- 1988-12-20 ES ES88850427T patent/ES2043891T3/es not_active Expired - Lifetime
- 1988-12-20 WO PCT/SE1988/000691 patent/WO1989005794A1/en active IP Right Grant
- 1988-12-20 EP EP88850427A patent/EP0322389B1/en not_active Expired - Lifetime
- 1988-12-20 AU AU28244/89A patent/AU2824489A/en active Granted
- 1988-12-20 AT AT88850427T patent/ATE81848T1/de not_active IP Right Cessation
- 1988-12-20 DE DE8888850427T patent/DE3875600T2/de not_active Expired - Fee Related
- 1988-12-20 WO PCT/SE1988/000692 patent/WO1989005795A1/en active Application Filing
- 1988-12-20 HU HU89359A patent/HU205895B/hu not_active IP Right Cessation
- 1988-12-21 IL IL10374188A patent/IL103741A/en not_active IP Right Cessation
- 1988-12-21 IL IL8874988A patent/IL88749A/en not_active IP Right Cessation
- 1988-12-21 IS IS3425A patent/IS1558B/is unknown
- 1988-12-21 PH PH37960A patent/PH26828A/en unknown
- 1988-12-21 PH PH37959A patent/PH25526A/en unknown
- 1988-12-22 IE IE883860A patent/IE883860L/xx unknown
- 1988-12-22 AU AU29103/89A patent/AU2910389A/en not_active Abandoned
- 1988-12-22 MY MYPI88001510A patent/MY103945A/en unknown
- 1988-12-22 PT PT89312A patent/PT89312B/pt not_active IP Right Cessation
- 1988-12-22 WO PCT/SE1988/000697 patent/WO1989005806A1/en unknown
- 1988-12-22 PT PT89311A patent/PT89311B/pt not_active IP Right Cessation
- 1988-12-22 EG EG653/88A patent/EG18681A/xx active
- 1988-12-22 US US07/289,630 patent/US5034411A/en not_active Expired - Fee Related
- 1988-12-22 IE IE883859A patent/IE883859L/xx unknown
- 1988-12-22 MX MX014310A patent/MX174084B/es unknown
- 1988-12-22 AR AR88312835A patent/AR247729A1/es active
- 1988-12-23 PL PL1988287936A patent/PL159551B1/pl unknown
- 1988-12-23 CN CN88108941A patent/CN1033804A/zh active Pending
- 1988-12-23 PL PL1988276698A patent/PL157747B1/pl unknown
- 1988-12-23 YU YU234088A patent/YU47580B/sh unknown
- 1988-12-28 DD DD88324296A patent/DD277274A5/de not_active IP Right Cessation
-
1989
- 1989-06-12 ZA ZA894441A patent/ZA894441B/xx unknown
- 1989-06-19 DD DD89329730A patent/DD295353A5/de not_active IP Right Cessation
- 1989-06-22 CN CN89104335A patent/CN1048214A/zh active Pending
- 1989-08-17 DK DK404789A patent/DK404789A/da not_active Application Discontinuation
- 1989-08-17 DK DK404889A patent/DK404889A/da unknown
- 1989-08-22 FI FI893937A patent/FI893937A/fi not_active Application Discontinuation
- 1989-08-22 NO NO893376A patent/NO171784C/no unknown
- 1989-08-22 RU SU894614813A patent/RU2024503C1/ru active
- 1989-08-22 KR KR1019890701579A patent/KR900700441A/ko not_active Application Discontinuation
- 1989-08-22 FI FI893936A patent/FI92192C/sv not_active IP Right Cessation
- 1989-08-22 NO NO893375A patent/NO171724C/no unknown
- 1989-08-22 RU SU894614909A patent/RU1836342C/ru active
- 1989-08-23 KR KR1019890701592A patent/KR900700442A/ko not_active Application Discontinuation
-
1990
- 1990-02-02 YU YU00196/90A patent/YU19690A/xx unknown
-
1991
- 1991-01-18 US US07/643,161 patent/US5155133A/en not_active Expired - Fee Related
- 1991-04-22 RU SU914895329A patent/RU1836343C/ru active
-
1992
- 1992-11-12 GR GR920402579T patent/GR3006241T3/el unknown
-
1993
- 1993-01-28 GR GR930400159T patent/GR3006912T3/el unknown
- 1993-06-30 LV LV930851A patent/LV10250A/xx unknown
- 1993-12-28 LT LTIP1687A patent/LTIP1687A/xx not_active Application Discontinuation
- 1993-12-28 LT LTIP1688A patent/LTIP1688A/xx not_active Application Discontinuation
- 1993-12-30 LT LTIP1720A patent/LTIP1720A/xx not_active Application Discontinuation
- 1993-12-31 LT LTIP1752A patent/LTIP1752A/xx not_active Application Discontinuation
-
1994
- 1994-05-31 CN CN94105497A patent/CN1097736A/zh active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19930216 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19950831 |