YU47116B - Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata - Google Patents

Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata

Info

Publication number
YU47116B
YU47116B YU211087A YU211087A YU47116B YU 47116 B YU47116 B YU 47116B YU 211087 A YU211087 A YU 211087A YU 211087 A YU211087 A YU 211087A YU 47116 B YU47116 B YU 47116B
Authority
YU
Yugoslavia
Prior art keywords
carbon atoms
alkyl
halogen
alkoxy
substituted
Prior art date
Application number
YU211087A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU211087A (en
Inventor
R.A. Bergman
H. Bundgaard
P.L. Lindberg
G.E. Sunden
Original Assignee
Aktiebolaget Hassle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE8604998A external-priority patent/SE8604998D0/xx
Priority claimed from SE8605551A external-priority patent/SE8605551D0/xx
Priority claimed from SE8704049A external-priority patent/SE8704049D0/xx
Application filed by Aktiebolaget Hassle filed Critical Aktiebolaget Hassle
Publication of YU211087A publication Critical patent/YU211087A/xx
Publication of YU47116B publication Critical patent/YU47116B/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
YU211087A 1986-11-21 1987-11-20 Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata YU47116B (sh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE8604998A SE8604998D0 (sv) 1986-11-21 1986-11-21 Novel pharmacological compounds
SE8605551A SE8605551D0 (sv) 1986-12-23 1986-12-23 Novel pharmacological compounds
SE8704049A SE8704049D0 (sv) 1987-10-16 1987-10-16 Novel pharmacological compounds

Publications (2)

Publication Number Publication Date
YU211087A YU211087A (en) 1988-12-31
YU47116B true YU47116B (sh) 1994-12-28

Family

ID=27355365

Family Applications (1)

Application Number Title Priority Date Filing Date
YU211087A YU47116B (sh) 1986-11-21 1987-11-20 Postupak za dobijanje novih n-supstituisanih benzimidazolskih derivata

Country Status (24)

Country Link
EP (3) EP0279149B1 (enrdf_load_html_response)
JP (1) JPH02500744A (enrdf_load_html_response)
KR (1) KR890700125A (enrdf_load_html_response)
AT (1) ATE84032T1 (enrdf_load_html_response)
AU (1) AU612129B2 (enrdf_load_html_response)
DE (1) DE3783356T2 (enrdf_load_html_response)
DK (1) DK365488A (enrdf_load_html_response)
EG (1) EG18379A (enrdf_load_html_response)
ES (1) ES2052603T3 (enrdf_load_html_response)
FI (1) FI892454A7 (enrdf_load_html_response)
GR (1) GR3007385T3 (enrdf_load_html_response)
HU (1) HU204814B (enrdf_load_html_response)
IE (2) IE61178B1 (enrdf_load_html_response)
IL (1) IL84504A (enrdf_load_html_response)
IS (1) IS1565B (enrdf_load_html_response)
LV (1) LV10954B (enrdf_load_html_response)
MY (1) MY101784A (enrdf_load_html_response)
NO (1) NO173998C (enrdf_load_html_response)
NZ (2) NZ234564A (enrdf_load_html_response)
PL (1) PL157655B1 (enrdf_load_html_response)
PT (1) PT86186B (enrdf_load_html_response)
RU (1) RU2062778C1 (enrdf_load_html_response)
WO (1) WO1988003921A1 (enrdf_load_html_response)
YU (1) YU47116B (enrdf_load_html_response)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8801907D0 (sv) * 1988-05-20 1988-05-20 Haessle Ab Novel pharmacological compounds
WO1990003373A1 (en) * 1988-09-20 1990-04-05 Hisamitsu Pharmaceutical Co., Inc. NOVEL DIBENZ[b,e]OXEPIN DERIVATIVES
SE8804629D0 (sv) * 1988-12-22 1988-12-22 Ab Haessle New therapeutically active compounds
EG19302A (en) * 1988-12-22 1994-11-30 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
US5049674A (en) * 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
SE9002206D0 (sv) 1990-06-20 1990-06-20 Haessle Ab New compounds
ES2140391T3 (es) * 1990-06-20 2000-03-01 Astra Ab Derivados de dialcoxi-piridinil-bencimidazol, procedimiento para su preparacion y su uso farmaceutico.
US5312824A (en) * 1990-10-17 1994-05-17 Takeda Chemical Industries, Ltd. Certain 2-[(4-difluoromethoxy-2-pyridyl)-methylthio or methylsulfinyl-5-benzimidazoles useful for treating peptic ulcers
SE9103776D0 (sv) * 1991-12-19 1991-12-19 Astra Ab New compounds
EP0604657B1 (en) * 1992-05-21 2000-01-12 Otsuka Pharmaceutical Factory, Inc. Phosphonic diester derivative
AU6556894A (en) * 1993-05-18 1994-12-12 Upjohn Company, The Bisphosphonate esters for treating gastric disorders
US6875872B1 (en) 1993-05-28 2005-04-05 Astrazeneca Compounds
SE508669C2 (sv) * 1996-04-26 1998-10-26 Astra Ab Nytt förfarande
JP2002510293A (ja) * 1997-05-30 2002-04-02 ドクター・レディーズ・リサーチ・ファウンデーション 抗潰瘍剤として新規なベンゾイミダゾール誘導体、それらの製造方法、及びそれらを含有する薬学的組成物
NZ505515A (en) * 1997-12-31 2003-03-28 Univ Kansas Water soluble prodrugs of secondary and tertiary amine containing drugs and methods of making thereof
ZA9810765B (en) * 1998-05-28 1999-08-06 Ranbaxy Lab Ltd Stable oral pharmaceutical composition containing a substituted pyridylsulfinyl benzimidazole.
US6420384B2 (en) 1999-12-17 2002-07-16 Ariad Pharmaceuticals, Inc. Proton pump inhibitors
WO2002030920A1 (fr) * 2000-10-12 2002-04-18 Takeda Chemical Industries, Ltd. Composes derives de benzimidazole, leur procede de production et leur utilisation
EP1437352A4 (en) * 2001-09-25 2004-12-08 Takeda Chemical Industries Ltd BENZIMIDAZOLE COMPOUND, METHOD FOR THE PRODUCTION AND USE THEREOF
KR100822981B1 (ko) * 2002-07-19 2008-04-16 윈스턴 파마슈티컬즈, 엘엘씨 벤즈이미다졸 유도체 및 이들의 프로톤 펌프 억제제의프로드럭으로서의 이용
GB0400781D0 (en) * 2004-01-14 2004-02-18 Novartis Ag Organic compounds
EP1781619B1 (en) * 2004-08-27 2011-08-17 Laboratorios Del Dr. Esteve, S.A. Sigma receptor inhibitors
CA2616512A1 (en) * 2005-07-28 2007-02-08 Intervet International B.V. Novel benzimidazole (thio) carbamates with antiparasitic activity and the synthesis thereof
US10272070B2 (en) 2014-10-14 2019-04-30 The Board of Trustees of the Leland Stanford Junio r University Method for treating neurodegenerative diseases
KR20180094989A (ko) 2015-12-15 2018-08-24 더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 주니어 유니버시티 노화 관련 인지장애 및 신경염증의 예방 및/또는 치료 방법
CA3108773A1 (en) 2018-08-06 2020-02-13 The Board Of Trustees Of The Leland Stanford Junior University 2-arylbenzimidazoles as ppargc1a activators for treating neurodegenerative diseases
CA3150303A1 (en) * 2019-08-20 2021-02-25 Ono Pharmaceutical Co., Ltd. Salt and crystal form of compound having agonistic activity to s1p5 receptor

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (enrdf_load_html_response) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
JPS5836312B2 (ja) * 1978-08-21 1983-08-08 日本電信電話株式会社 通信用平衡ケ−ブル線路の障害位置測定方式
JPS5687818A (en) * 1979-12-19 1981-07-16 Ishikawajima Harima Heavy Ind Co Ltd Reflex type position detector
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
JPS57137860A (en) * 1981-02-20 1982-08-25 Sumitomo Electric Ind Ltd Optical tachometer
JPS5999597A (ja) * 1982-11-30 1984-06-08 株式会社東芝 光学測定装置
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
JPS6020051U (ja) * 1983-07-19 1985-02-12 三洋電機株式会社 カセツト収納装置
AU568441B2 (en) 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds

Also Published As

Publication number Publication date
PL268927A1 (en) 1989-01-23
EP0279149A2 (en) 1988-08-24
EP0332647A1 (en) 1989-09-20
WO1988003921A1 (en) 1988-06-02
KR890700125A (ko) 1989-03-02
NO173998B (no) 1993-11-22
JPH02500744A (ja) 1990-03-15
EP0279149B1 (en) 1992-12-30
EP0510719A1 (en) 1992-10-28
NZ222495A (en) 1991-04-26
IL84504A (en) 1994-10-07
MY101784A (en) 1992-01-17
IE873125L (en) 1988-05-21
DK365488D0 (da) 1988-07-01
HUT51269A (en) 1990-04-28
DK365488A (da) 1988-07-01
ES2052603T3 (es) 1994-07-16
NO883229D0 (no) 1988-07-20
EG18379A (en) 1992-11-30
IS1565B (is) 1994-12-13
RU2062778C1 (ru) 1996-06-27
IS3284A7 (is) 1988-05-22
AU8330287A (en) 1988-06-16
LV10954B (en) 1996-08-20
PT86186B (pt) 1990-08-31
GR3007385T3 (enrdf_load_html_response) 1993-07-30
HU204814B (en) 1992-02-28
NO883229L (no) 1988-09-16
PL157655B1 (pl) 1992-06-30
FI892454L (fi) 1989-05-19
IE940326L (en) 1988-05-21
AU612129B2 (en) 1991-07-04
FI892454A0 (fi) 1989-05-19
ATE84032T1 (de) 1993-01-15
NZ234564A (en) 1991-04-26
PT86186A (en) 1987-12-01
DE3783356T2 (de) 1993-04-15
FI892454A7 (fi) 1989-05-19
LV10954A (lv) 1995-12-20
NO173998C (no) 1994-03-02
IE61178B1 (en) 1994-10-05
EP0279149A3 (en) 1988-08-31
DE3783356D1 (de) 1993-02-11
YU211087A (en) 1988-12-31

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