YU45690B - Postopek za pripravo 9-(2-hidroksietoksimetil)-gvanina - Google Patents
Postopek za pripravo 9-(2-hidroksietoksimetil)-gvaninaInfo
- Publication number
- YU45690B YU45690B YU219084A YU219084A YU45690B YU 45690 B YU45690 B YU 45690B YU 219084 A YU219084 A YU 219084A YU 219084 A YU219084 A YU 219084A YU 45690 B YU45690 B YU 45690B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- hydroxyethoxymethyl
- guanine
- procedure
- preparing
- acyl
- Prior art date
Links
- MKUXAQIIEYXACX-UHFFFAOYSA-N aciclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCO)C=N2 MKUXAQIIEYXACX-UHFFFAOYSA-N 0.000 title abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
POSTOPEK ZA PRIPRAVO 9-(2-HIDROKSIETOKSIMETIL)-GVANINA, s formulo označen s tem, da spojino s splošno formulo I v kateri sta R in R' enaka ali različna in pomenita vodik, C1 - C8 - acil ali benzil in R1 (C1-C8) acil, hidroliziramo ob milih bazičnih pogojih. Prijava vsebuje še 8 patentnih zahtevkov.
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU219084A YU45690B (sh) | 1984-12-22 | 1984-12-22 | Postopek za pripravo 9-(2-hidroksietoksimetil)-gvanina |
US06/807,724 US4701526A (en) | 1984-12-22 | 1985-12-11 | Process for preparing 9-(2-hydroxyethoxymethyl)-guanine, and intermediates useful in said process |
DE19853544461 DE3544461A1 (de) | 1984-12-22 | 1985-12-16 | Verfahren zur herstellung von 9-(2-hydroxyaethoxymethyl)-guanin, neue, in diesem verfahren verwendbare zwischenprodukte und verfahren zur herstellung dieser neuen zwischenprodukte |
SU853990801A SU1454253A3 (ru) | 1984-12-22 | 1985-12-19 | Способ получени 9-(2-оксиэтоксиметил)гуанина |
AT0368385A AT386826B (de) | 1984-12-22 | 1985-12-19 | Verfahren zur herstellung von 9-(2hydroxy|thoxymethyl) -guanin |
JP60285863A JPS61155386A (ja) | 1984-12-22 | 1985-12-20 | 9―(2―ヒドロキシエトキシメチル)―グアニンの製法 |
PL1985256987A PL147434B1 (en) | 1984-12-22 | 1985-12-20 | Method of obtaining 9-/2-hydroxyetoxymethyl/guanine |
DD85284916A DD246301A5 (de) | 1984-12-22 | 1985-12-20 | Verfahren zur herstellung von 9-(2-hydroxyaethoxy-methyl)granin |
CS859666A CS272215B2 (en) | 1984-12-22 | 1985-12-20 | Method of 9-/-hydroxyethoxymethyl/guanine production |
HU854923A HU196207B (en) | 1984-12-22 | 1985-12-20 | Process for preparing 9-/2-hydroxy-ethoxy/-methyl-guanine |
CS865215A CS272219B2 (en) | 1984-12-22 | 1986-07-09 | Method of new guanine derivatives production |
US07/109,372 US4826981A (en) | 1984-12-22 | 1987-10-19 | Process for preparing 9-(2-hydroxyethoxymethyl)-guanine |
JP3258637A JPH0714937B2 (ja) | 1984-12-22 | 1991-09-11 | グリオキサール−n2 −グアニン付加物およびその製法 |
JP3258636A JPH0714936B2 (ja) | 1984-12-22 | 1991-09-11 | グリオキサール−n2 −アセチルグアニン付加物およびその製法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU219084A YU45690B (sh) | 1984-12-22 | 1984-12-22 | Postopek za pripravo 9-(2-hidroksietoksimetil)-gvanina |
Publications (2)
Publication Number | Publication Date |
---|---|
YU219084A YU219084A (en) | 1987-08-31 |
YU45690B true YU45690B (sh) | 1992-07-20 |
Family
ID=25557168
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU219084A YU45690B (sh) | 1984-12-22 | 1984-12-22 | Postopek za pripravo 9-(2-hidroksietoksimetil)-gvanina |
Country Status (10)
Country | Link |
---|---|
US (1) | US4701526A (sh) |
JP (3) | JPS61155386A (sh) |
AT (1) | AT386826B (sh) |
CS (1) | CS272215B2 (sh) |
DD (1) | DD246301A5 (sh) |
DE (1) | DE3544461A1 (sh) |
HU (1) | HU196207B (sh) |
PL (1) | PL147434B1 (sh) |
SU (1) | SU1454253A3 (sh) |
YU (1) | YU45690B (sh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4916225A (en) * | 1986-11-25 | 1990-04-10 | Institut Organicheskogo Sinteza Akademii Nauk Latviiskoi Ssr | 9-substituted guanines |
EP0289992B1 (en) * | 1987-05-04 | 1994-04-27 | Kemijski Institut | Process for preparing purine derivates |
GB8724765D0 (en) * | 1987-10-22 | 1987-11-25 | Beecham Group Plc | Process |
JPH0219546A (ja) * | 1988-07-01 | 1990-01-23 | Nippon Tungsten Co Ltd | 織機用ウォータージェットノズル |
ES2047457B1 (es) * | 1992-08-03 | 1994-10-01 | Union Quimico Farma | Procedimiento para obtener aciclovir. |
DE19839013B4 (de) | 1998-08-27 | 2004-08-26 | Degussa Ag | Verfahren zur Hestellung von Guanin |
DE19857949A1 (de) | 1998-12-16 | 2000-06-21 | Degussa | Verfahren zur Herstellung von Guanin unter Druck |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4199574A (en) * | 1974-09-02 | 1980-04-22 | Burroughs Wellcome Co. | Methods and compositions for treating viral infections and guanine acyclic nucleosides |
US4146715A (en) * | 1975-08-27 | 1979-03-27 | Burroughs Wellcome Co. | 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines |
YU41079B (en) * | 1976-08-27 | 1986-12-31 | Wellcome Found | Process for the synthesis of substituted purine compounds |
BE863525A (fr) * | 1977-02-14 | 1978-07-31 | Bristol Myers Co | Heterocyclopyrimidines |
IL64501A (en) * | 1980-12-22 | 1985-07-31 | Astra Laekemedel Ab | 9-substituted 4-hydroxybutyl guanine derivatives,their preparation and antiviral use |
-
1984
- 1984-12-22 YU YU219084A patent/YU45690B/sh unknown
-
1985
- 1985-12-11 US US06/807,724 patent/US4701526A/en not_active Expired - Fee Related
- 1985-12-16 DE DE19853544461 patent/DE3544461A1/de not_active Withdrawn
- 1985-12-19 SU SU853990801A patent/SU1454253A3/ru active
- 1985-12-19 AT AT0368385A patent/AT386826B/de not_active IP Right Cessation
- 1985-12-20 JP JP60285863A patent/JPS61155386A/ja active Granted
- 1985-12-20 PL PL1985256987A patent/PL147434B1/pl unknown
- 1985-12-20 DD DD85284916A patent/DD246301A5/de unknown
- 1985-12-20 CS CS859666A patent/CS272215B2/cs unknown
- 1985-12-20 HU HU854923A patent/HU196207B/hu not_active IP Right Cessation
-
1991
- 1991-09-11 JP JP3258637A patent/JPH0714937B2/ja not_active Expired - Lifetime
- 1991-09-11 JP JP3258636A patent/JPH0714936B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CS272215B2 (en) | 1991-01-15 |
YU219084A (en) | 1987-08-31 |
JPH05255328A (ja) | 1993-10-05 |
JPS61155386A (ja) | 1986-07-15 |
DD246301A5 (de) | 1987-06-03 |
HUT41028A (en) | 1987-03-30 |
HU196207B (en) | 1988-10-28 |
ATA368385A (de) | 1988-03-15 |
AT386826B (de) | 1988-10-25 |
JPH05255329A (ja) | 1993-10-05 |
JPH0714937B2 (ja) | 1995-02-22 |
CS966685A2 (en) | 1990-03-14 |
US4701526A (en) | 1987-10-20 |
PL147434B1 (en) | 1989-06-30 |
JPH0529228B2 (sh) | 1993-04-28 |
PL256987A1 (en) | 1988-03-03 |
DE3544461A1 (de) | 1986-07-03 |
SU1454253A3 (ru) | 1989-01-23 |
JPH0714936B2 (ja) | 1995-02-22 |
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