ES8605531A1 - Procedimiento para preparar glucopiranosidos. - Google Patents

Procedimiento para preparar glucopiranosidos.

Info

Publication number
ES8605531A1
ES8605531A1 ES542416A ES542416A ES8605531A1 ES 8605531 A1 ES8605531 A1 ES 8605531A1 ES 542416 A ES542416 A ES 542416A ES 542416 A ES542416 A ES 542416A ES 8605531 A1 ES8605531 A1 ES 8605531A1
Authority
ES
Spain
Prior art keywords
pct
didesoxyhexose
diamino
derivatives
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES542416A
Other languages
English (en)
Other versions
ES542416A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19843415100 external-priority patent/DE3415100A1/de
Priority claimed from DE19843415102 external-priority patent/DE3415102A1/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES542416A0 publication Critical patent/ES542416A0/es
Publication of ES8605531A1 publication Critical patent/ES8605531A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
    • C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
    • C07H5/06—Aminosugars
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/416—2,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04—Phosphates; Phosphites; Polyphosphates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR GLUCOPIRANOSIDOS. COMPRENDE: A) DILUIR A UN COMPUESTO DE FORMULA (II) EN UN DISOLVENTE INERTE COMO UN ETER CICLICO TETRAHIDROFURANO; B) HACER REACCIONAR A (II) DE A) CON BUTIL-LITIO, EN HEXANO Y C70JC; Y C) TRATAR AL PRODUCTO DE B) CON FOSFOROCLORIDATO PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: RII1, H, ALQUILO INFERIOR Y OTROS; R2 Y R3 UN ACILO INSUSTITUIDO O SUSTITUIDO; R4, FOSFATO, PIROFOSFATO FOSFORILETANOLAMINA Y OTROS; R5, H O GLICOSILO; RI4, H O UN GRUPO PROTECTOR; Y RI5, GRUPO PROTECTOR O GLICOSILO. SE UTILIZAN COMO INMUNOESTIMULANTES.
ES542416A 1984-04-21 1985-04-19 Procedimiento para preparar glucopiranosidos. Expired ES8605531A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19843415100 DE3415100A1 (de) 1984-04-21 1984-04-21 Neue 2,3-diamino-2,3-didesoxyhexosederivate, verfahren zu ihrer herstellung und ihre verwendung
DE19843415102 DE3415102A1 (de) 1984-04-21 1984-04-21 Neue 2,3-diamino-2,3-didesoxyhexosederivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
ES542416A0 ES542416A0 (es) 1986-03-16
ES8605531A1 true ES8605531A1 (es) 1986-03-16

Family

ID=25820628

Family Applications (1)

Application Number Title Priority Date Filing Date
ES542416A Expired ES8605531A1 (es) 1984-04-21 1985-04-19 Procedimiento para preparar glucopiranosidos.

Country Status (16)

Country Link
US (1) US4698331A (es)
EP (1) EP0180608B1 (es)
AT (1) ATE54920T1 (es)
AU (1) AU580061B2 (es)
CA (1) CA1264739A (es)
DE (1) DE3578866D1 (es)
DK (1) DK600585D0 (es)
ES (1) ES8605531A1 (es)
FI (1) FI81807C (es)
GR (1) GR850955B (es)
HU (1) HU197584B (es)
IL (1) IL75042A (es)
NZ (1) NZ211846A (es)
PH (1) PH23127A (es)
PT (1) PT80320B (es)
WO (1) WO1985004881A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8601551A (nl) * 1985-06-28 1987-01-16 Sandoz Ag Nieuwe saccharides, hun bereiding en farmaceutische samenstellingen, die hen bevatten.
DE3731953A1 (de) 1987-09-23 1989-04-06 Sandoz Ag Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung
US5219843A (en) * 1987-09-23 1993-06-15 Sandoz Ltd. Saccharide derivatives
US7038039B2 (en) * 2000-02-10 2006-05-02 Mitsui Chemicals, Inc. Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78246B (es) * 1981-01-23 1984-09-26 Ciba Geigy Ag
US4384998A (en) * 1981-03-30 1983-05-24 Merck & Co., Inc. Synthesis of thienamycin from D-glucose
DE3220426A1 (de) * 1982-05-29 1983-12-01 Behringwerke Ag, 3550 Marburg Chemische verbindung, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der malaria
JPS60501259A (ja) * 1983-05-06 1985-08-08 ウイスコンシン・アルムニ・リサ−チ・フアンデ−シヨン 免疫刺激活性をもつ単糖類化合物
US4481196A (en) * 1983-08-31 1984-11-06 Fujisawa Pharmaceutical Co., Ltd. Glycoside phosphate derivatives, pharmaceutical composition of the same and method of use
DE3347163A1 (de) * 1983-12-27 1985-07-04 Behringwerke Ag, 3550 Marburg Verwendung von oligosacchariden zur chemotherapie oder chemoprophylaxe der malaria
US4481198A (en) * 1984-02-13 1984-11-06 Wisconsin Alumni Research Foundation Vitamin D metabolism inhibitor

Also Published As

Publication number Publication date
US4698331A (en) 1987-10-06
HUT42099A (en) 1987-06-29
IL75042A0 (en) 1985-08-30
NZ211846A (en) 1989-07-27
ES542416A0 (es) 1986-03-16
IL75042A (en) 1989-05-15
DK600585A (da) 1985-12-20
AU4238085A (en) 1985-11-15
DE3578866D1 (de) 1990-08-30
GR850955B (es) 1985-11-25
CA1264739A (en) 1990-01-23
ATE54920T1 (de) 1990-08-15
EP0180608A1 (en) 1986-05-14
AU580061B2 (en) 1988-12-22
EP0180608B1 (en) 1990-07-25
PT80320B (en) 1987-02-16
PT80320A (en) 1985-05-01
HU197584B (en) 1989-04-28
FI855132A (fi) 1985-12-20
FI855132A0 (fi) 1985-12-20
DK600585D0 (da) 1985-12-20
FI81807C (fi) 1990-12-10
PH23127A (en) 1989-05-05
FI81807B (fi) 1990-08-31
WO1985004881A1 (en) 1985-11-07

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